Modest Evidence (modest + evidence)

Distribution by Scientific Domains


Selected Abstracts


Projected Alcohol Dose Influences on the Activation of Alcohol Expectancies in College Drinkers

ALCOHOLISM, Issue 7 2009
Jennifer P. Read
Background:, Alcohol expectancies have been linked to drinking behavior in college students, and vary according to a number of factors, including projected dose of alcohol. Research using Multidimensional Scaling (MDS) suggests that drinking may be influenced by activation of differing expectancy dimensions in memory, yet studies have not examined expectancy activation according to projected alcohol doses. Methods:, The present study used Individual Differences Scaling (INDSCAL) to map expectancy networks of college students (n = 334) who imagined varied drinking at high and low alcohol doses. Expectancy activation was modeled by dose, as well as by gender and by drinking patterns (typical quantity, blood alcohol content, heavy episodic drinking, and alcohol consequences). Expectancies were organized along positive,negative and arousal,sedation dimensions. Anticipation of a high dose of alcohol was associated with greater emphasis on the arousal,sedation dimension, whereas anticipation of a lower dose was associated with greater emphasis on the positive,negative dimension. Results:, Across heavy, medium, and light drinkers, expectancy dimensions were most distinguishable at higher doses; activation patterns were more similar across drinking groups at lighter doses. Modest evidence for the influence of gender on activation patterns was observed. Findings were consistent across alcohol involvement indices. Conclusions:, These data suggest that both dimensionality and context should be considered in the refinement of interventions designed to alter expectancies in order to decrease hazardous drinking. [source]


Does partnership at work increase trust?

INDUSTRIAL RELATIONS JOURNAL, Issue 2 2008
An analysis based on the 2004 Workplace Employment Relations Survey
ABSTRACT In the late 1990s, partnership at work was embraced with some enthusiasm by a number of stakeholders in employment relations and incorporated in the 1999 Employment Relations Act. The implementation of the Information and Consultation Regulations has also been extensively signalled. We might therefore expect to see some evidence of partnership-related practices in Britain. The 2004 Workplace Employment Relations Survey (WERS 2004) provides an opportunity to explore the extent of partnership practice, and also, for the first time, to explore its link to trust relations. This article reports evidence from WERS 2004 suggesting that partnership practice remains relatively undeveloped and that it is only weakly related to trust between management and employee representatives and to employees' trust in management. Direct forms of participation generally have a more positive association with trust than representative forms. There is also modest evidence that trust may be associated with certain workplace outcomes. The case for partnership and more particularly representative partnership as a basis for mutuality and trust is not supported by this evidence. [source]


Constraints on union organising in the United Kingdom

INDUSTRIAL RELATIONS JOURNAL, Issue 1 2008
Edmund Heery
ABSTRACT Despite increased investment by unions in organising, across much of the developed world there is at best modest evidence of a recovery of union membership. This has led to a research interest in the barriers to successful union organising and it is with this critical issue that the following article is concerned. It uses survey and interview data from trainee organisers in Britain to identify the internal and external constraints they have encountered while working on organising campaigns. The findings point to a broad range of organising constraints both within and beyond trade unions. Experience of constraints varies and is shown partly to be a function of the characteristics of organisers, the nature of the organising task in which they are engaged and the systems in place to manage their work. [source]


The Effect of Later Life Parental Divorce on Adult-Child/Older-Parent Solidarity: A Test of the Buffering Hypothesis,

JOURNAL OF APPLIED SOCIAL PSYCHOLOGY, Issue 6 2003
Paul A. Nakonezny
The present study examined the effect of later life parental divorce on solidarity in the relationship between the adult child and older parent. This examination was achieved by testing the buffering hypothesis. A cross-sectional quasiexperimental pre-post treatment design was used (Cook & Campbell, 1979), with retrospective pretests and data from 100 adult-child/older-parent dyads. The ANOVA results show that the mother/adult-child relationship with a higher degree of predivorce solidarity responded to later life parental divorce with less disruption of affectional solidarity and associational solidarity than those with a lower degree of predivorce solidarity. Thus, the current research provides modest evidence (for the mother/adult-child relationship) to support the buffering hypothesis. We found no evidence of a buffering effect for the father-child relationship. [source]


Welfare Reform and Teenage Pregnancy, Childbirth, and School Dropout

JOURNAL OF MARRIAGE AND FAMILY, Issue 1 2004
Lingxin Hao
This study estimates the effect of welfare reform on adolescent behaviors using a difference-in-differences approach. After defining the prereform and reform cohorts and considering the life course development of adolescent behavior by following each cohort from age 14 to age 16, we compare the welfare-target and nontarget populations in the two cohorts. The difference-in-differences estimates are obtained using an event history model. Our analysis suggests that welfare reform has not reduced teenage fertility and school dropout. We find modest evidence that welfare reform is associated with higher risk of teenage births for girls in welfare families and higher risk of school dropout for girls in poor families. A combination of a difference-in-differences approach and a life course perspective can be a useful way to delineate the effect of societal-level change on family phenomena. [source]


Mind-Body Interventions During Pregnancy

JOURNAL OF OBSTETRIC, GYNECOLOGIC & NEONATAL NURSING, Issue 2 2008
Amy E. Beddoe
ABSTRACT Objective:, To examine published evidence on the effectiveness of mind-body interventions during pregnancy on perceived stress, mood, and perinatal outcomes. Data sources:, Computerized searches of PubMed, Cinahl, PsycINFO, and the Cochrane Library. Study Selection:, Twelve out of 64 published intervention studies between 1980 and February 2007 of healthy, adult pregnant women met criteria for review. Data extraction and synthesis:, Studies were categorized by type of mind-body modality used. Progressive muscle relaxation was the most common intervention. Other studies used a multimodal psychoeducation approach or a yoga and meditation intervention. The research contained methodological problems, primarily absence of a randomized control group or failure to adequately control confounding variables. Nonetheless, there was modest evidence for the efficacy of mind-body modalities during pregnancy. Treatment group outcomes included higher birthweight, shorter length of labor, fewer instrument-assisted births, and reduced perceived stress and anxiety. Conclusions:, There is evidence that pregnant women have health benefits from mind-body therapies used in conjunction with conventional prenatal care. Further research is necessary to build on these studies in order to predict characteristics of subgroups that might benefit from mind-body practices and examine cost effectiveness of these interventions on perinatal outcomes. [source]


Maternal periconceptional vitamin use, genetic variation of infant reduced folate carrier (A80G), and risk of spina bifida

AMERICAN JOURNAL OF MEDICAL GENETICS, Issue 1 2002
Gary M. Shaw
Abstract Women who consume folic acid in early pregnancy reduced their risks for delivering offspring with neural tube defects (NTDs). The underlying process by which folic acid facilitated this risk reduction is unknown. Investigating genetic variation that influences cellular absorption, transport, and metabolism of folate will help fill this data gap. We focused our studies on a candidate gene that is involved in folate transport, the reduced folate carrier 1 (RFC1). Using data from a California population,based case control interview study (1989,1991 birth cohorts), we investigated whether spina bifida risk was influenced by an interaction between a polymorphism of infant RFC1 at nucleotide 80 (A80G) and maternal periconceptional use of vitamins containing folic acid. Allelic variants of RFC1 were determined by genotyping 133 live-born spina bifida case infants and 188 control infants. The percentages of case infants with the A80/A80, G80/G80, and G80/A80 genotypes were 27.2%, 28.0%, and 44.7%, respectively. The percentages of control infants were similar: 26.1%, 29.3%, and 44.7%. Odds ratios of 1.0 (95% confidence interval 0.5,2.0) for the G80/G80 genotype and 1.1 (0.6,2.0) for the G80/A80 genotype were observed relative to the A80/A80 genotype. Among mothers who did not use vitamins, spina bifida risk was 2.4 (0.8,6.9) for infants with genotype G80/G80 compared to those with A80/A80 genotype. Among mothers who did use vitamins, the risk was 0.5 (0.1,3.1) for infants with the G80/G80 genotype. Although this study did not find an increased spina bifida risk for infants who were heterozygous or homozygous for RFC1 A80G, it did reveal modest evidence for a gene-nutrient interaction between infant homozygosity for the RFC1 G80/G80 genotype and maternal periconceptional intake of vitamins containing folic acid on the risk of spina bifida. © 2002 Wiley-Liss, Inc. [source]


Model Specification and Risk Premia: Evidence from Futures Options

THE JOURNAL OF FINANCE, Issue 3 2007
MARK BROADIE
ABSTRACT This paper examines model specification issues and estimates diffusive and jump risk premia using S&P futures option prices from 1987 to 2003. We first develop a time series test to detect the presence of jumps in volatility, and find strong evidence in support of their presence. Next, using the cross section of option prices, we find strong evidence for jumps in prices and modest evidence for jumps in volatility based on model fit. The evidence points toward economically and statistically significant jump risk premia, which are important for understanding option returns. [source]


Association of the IL2RA/CD25 gene with juvenile idiopathic arthritis

ARTHRITIS & RHEUMATISM, Issue 1 2009
Anne Hinks
Objective IL2RA/CD25, the gene for interleukin-2 receptor ,, is emerging as a general susceptibility gene for autoimmune diseases because of its role in the development and function of regulatory T cells and the association of single-nucleotide polymorphisms (SNPs) within this gene with type 1 diabetes mellitus (DM), Graves' disease, rheumatoid arthritis (RA), and multiple sclerosis (MS). The aim of this study was to determine whether SNPs within the IL2RA/CD25 gene are associated with juvenile idiopathic arthritis (JIA). Methods Three SNPs within the IL2RA/CD25 gene, that previously showed evidence of an association with either RA, MS, or type 1 DM, were selected for genotyping in UK JIA cases (n = 654) and controls (n = 3,849). Data for 1 SNP (rs2104286) were also available from North American JIA cases (n = 747) and controls (n = 1,161). Association analyses were performed using Plink software. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated. Results SNP rs2104286 within the IL2RA/CD25 gene was significantly associated with UK JIA cases (OR for the allele 0.76 [95% CI 0.66,0.88], P for trend = 0.0002). A second SNP (rs41295061) also showed modest evidence for association with JIA (OR 0.80 [95% CI 0.63,1.0], P = 0.05). Association with rs2104286 was convincingly replicated in the North American JIA cohort (OR 0.84 [95% CI 0.65,0.99], P for trend = 0.05). Meta-analysis of the 2 cohorts yielded highly significant evidence of association with JIA (OR 0.76 [95% CI 0.62,0.88], P = 4.9 × 10,5). Conclusion These results provide strong evidence that the IL2RA/CD25 gene represents a JIA susceptibility locus. Further investigation of the gene using both genetic and functional approaches is now required. [source]