Minor Constituents (minor + constituent)

Distribution by Scientific Domains


Selected Abstracts


Synthesis of (,)-Epicatechin 3-(3- O -Methylgallate) and (+)-Catechin 3-(3- O -Methylgallate), and Their Anti-Inflammatory Activity

CHEMISTRY & BIODIVERSITY, Issue 4 2009
Takashi Iijima
Abstract A concise synthesis of (,)-epicatechin 3-(3- O -methylgallate) (1; ECG3,Me), which is a minor constituent of tea, and (+)-catechin 3-(3- O -methylgallate) (2; CG3,Me) via condensation of equimolar amount of catechin and gallate derivatives has been achieved. The anti-inflammatory effect of the synthetic compounds on 12- O -tetradecanoylphorbol-13-acetate (TPA)-induced inflammation of mouse ears was examined. Compounds 1 and 2 suppressed the TPA-induced inflammation of mouse ears by 50 and 43%, respectively, at a dose of 200,,g. Their activities are stronger than those of indomethacin and glycyrrhetinic acid, the normally used anti-inflammatory agents. [source]


Chemical composition of the volatiles of Hemidesmus indicus R. Br.

FLAVOUR AND FRAGRANCE JOURNAL, Issue 3 2001
S. Nagarajan
Abstract The fragrant roots of Hemidesmus indicus (Indian sarsaparilla) is used in Indian native medicine and herbal tea preparations. The volatiles obtained by steam distillation (yield, 0.25%) contained 2-hydroxy-4-methoxybenzaldehyde (91%) and (,) ledol (4.5%), which are isolable in pure form, as the major constituents. The GC,MS analysis of the residual oil showed the presence of over 40 minor constituents. Among them, nerolidol (1.2%), borneol (0.3%), linalyl acetate (0.2%), dihydrocarvyl acetate (0.1%), salicylaldehyde (0.1%), isocaryophyllene (0.1%), ,-terpinyl acetate (traces) and 1,8-cineol (traces) are important as aromatic and bio-active principles. Copyright © 2001 John Wiley & Sons, Ltd. [source]


Antiatherogenic properties of lipid minor constituents from seed oils

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, Issue 12 2003
Haralabos C Karantonis
Abstract A number of lines of evidence suggest that seed oils exhibit a protective effect against atherogenesis. Most of the protective compounds are still unidentified. In this study, polar lipids of seed oil samples from sesame, corn and sunflower were successively fractionated by high-performance liquid chromatography. Each isolated lipid compound was tested in vitro for its ability to inhibit platelet-activating factor (PAF) and thrombin-induced washed rabbit platelet aggregation or to cause platelet aggregation. A significant number of lipids that exerted the above biological activities were detected. The most biologically active compounds were subjected to biological, chemical and spectroscopic analyses, and their structural data are presented. These results give a different explanation for the antiatherogenic action that seed oils exert. Given that PAF plays a pivotal role in atherogenesis, the fact that these oils contain PAF antagonists suggests their high nutritional value. Copyright © 2003 Society of Chemical Industry [source]


Proximate biochemical variations in eggs of the prawn Macrobrachium americanum (Bate, 1869) during its embryonic development

AQUACULTURE RESEARCH, Issue 5 2009
Marcelo García-Guerrero
Abstract Eggs of seven females were sampled to analyse the lipid, protein and carbohydrate content during the embryonic development of the prawn Macrobrachium americanum. Sampling was performed from recently spawned eggs to hatching. A hundred of eggs were sampled every 48 h during the trial. Proteins, lipids and carbohydrates were quantified. Proteins were the most abundant component, followed by lipids and carbohydrates as only minor constituents. Lipid decreased significantly from 42% to 23% of the total composition, while proteins increased from 55% to 76% and carbohydrates varied inconsistently. The change in total energy per egg through time during the embryonic development is represented by the equation y=,0.0133x+0.334; r2=0.94 (y represents the energy content and x represents days). The main energy provider was lipids whose energy consumption is described by the equation y=,0.0158x+0.203; r2=0.96. [source]