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Mild Synthesis (mild + synthesis)

Distribution by Scientific Domains
Chemistry100%

Selected Abstracts

Mild Synthesis of ,-Amino-,,,-difluoro Ketones from Acylsilanes and Trifluoromethyltrimethylsilane in a One-Pot Imino Aldol Reaction,

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 20 2005
Sylvain Jonet
Abstract ,-Amino-,,,-difluoro ketones have been very conveniently prepared in a one-pot procedure from acylsilanes, trifluoromethyltrimethylsilane and imines. The key intermediate in this reaction is a difluoroenoxysilane. The Lewis acid promoted imino aldol reaction was performed with BF3·OEt2 or under very mild conditions using a catalytic amount of Yb(OTf)3. The reaction with chiral benzylimines occurred in good yield with 52,78,% de. Palladium-catalyzed hydrogenolysis furnished an unprotected ,-amino-,,,-difluoro ketone or a ,-amino-,,,-difluoro alcohol. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005) [source]

A Mild Synthesis of ,,,,-[Iminobismethylene]bis [6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol].

CHEMINFORM, Issue 21 2007
Yihui Bai
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]

Copper-Mediated Cross-Coupling of H-Phosphonates with Vinyliodonium Salts: A Novel Very Mild Synthesis of 2-Arylvinylphosphonates.

CHEMINFORM, Issue 27 2005
Sabine Thielges
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

A Mild Synthesis of Unsymmetrical Bis-Alkoxysilanes Through Catalyzed Alcoholysis of Hydridosilanes.

CHEMINFORM, Issue 7 2005
Colleen N. Scott
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

A Straightforward and Mild Synthesis of Functionalized 3-Alkynoates.

CHEMINFORM, Issue 42 2004
Andres Suarez
Abstract For Abstract see ChemInform Abstract in Full Text. [source]