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Microfluidic Reactors (microfluidic + reactor)
Selected AbstractsA Microfluidic Approach for the Formation of Conductive Nanowires and Hollow Hybrid StructuresADVANCED MATERIALS, Issue 20 2010Josep Puigmartí-Luis A facile fabrication process for micro- and nanometer-scale hybrid structures employing a microfluidic reactor is described. The unique properties of hydrodynamic flow focusing are exploited to promote the formation of well-defined structures with dissimilar morphology and structure in a fast and simple way. The hybrid nanowires are potential candidates for nanometer-sized sensors due to their electrical conductivity and their ease of functionalization. [source] A Microfluidic Approach to the Rapid Screening of Palladium-Catalysed Aminocarbonylation ReactionsADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 18 2009Philip Abstract The evaluation and selection of the most appropriate catalyst for a chemical transformation is an important process in many areas of synthetic chemistry. Conventional catalyst screening involving batch reactor systems can be both time-consuming and expensive, resulting in a large number of individual chemical reactions. Continuous flow microfluidic reactors are increasingly viewed as a powerful alternative format for reacting and processing larger numbers of small-scale reactions in a rapid, more controlled and safer fashion. In this study we demonstrate the use of a planar glass microfluidic reactor for performing the three-component palladium-catalysed aminocarbonylation reaction of iodobenzene, benzylamine and carbon monoxide to form N -benzylbenzamide, and screen a series of palladium catalysts over a range of temperatures. N -Benzylbenzamide product yields for this reaction were found to be highly dependent on the nature of the catalyst and reaction temperature. The majority of catalysts gave good to high yields under typical flow conditions at high temperatures (150,°C), however the palladium(II) chloride-Xantphos complex [PdCl2(Xantphos)] proved to be far superior as a catalyst at lower temperatures (75,120,°C). The utilised method was found to be an efficent and reliable way for screening a large number of palladium-catalysed carbonylation reactions and may prove useful in screening other gas/liquid phase reactions. [source] Radiolabelling with short-lived PET (positron emission tomography) isotopes using microfluidic reactorsJOURNAL OF CHEMICAL TECHNOLOGY & BIOTECHNOLOGY, Issue 3 2009Philip W Miller Abstract This mini-review covers the issues concerning the application of microfluidics towards radiolabelling with short-lived isotopes used for PET (positron emission tomography), and surveys the literature in this area. The application of microfluidic reactors to radiolabelling reactions is currently receiving a great deal of interest because of the potential advantages they have over conventional labelling systems. The volume and variety of radiolabelling reactions for PET is expected to grow markedly over the coming years due to increased demands for PET scanning. High demands and expectations for radiolabelled compounds will have to be met by exploiting new types of chemistry and technologies, such as microfluidics, to improve the production and development of PET tracers. Copyright © 2008 Society of Chemical Industry [source] | ||||||||||