Measuring Range (measuring + range)

Distribution by Scientific Domains


Selected Abstracts


High-sensitivity surface micromachinable accelerometer using a ferroelectric substrate and its characterization

IEEJ TRANSACTIONS ON ELECTRICAL AND ELECTRONIC ENGINEERING, Issue 3 2007
Seiji Aoyagi Member
Abstract The present study reports the fabrication and characterization of a high-sensitivity surface micromachinable accelerometer using a ferroelectric material having a large dielectric constant, such as bulk PZT (,r = 2600). The measurement principle is the detection of capacitance change with respect to the dielectric mass movement in the fringe electrical field. Considering the practical fabrication, a ferroelectric material is used for the substrate instead of the suspended proof mass. Since capacitance is increased not mechanically but electrically, high sensitivity can be expected while maintaining mechanical stiffness, which has the advantage of preventing touch down of the proof mass and widening the allowable measuring range of acceleration. A fabricated sensor is characterized. A high sensitivity of several sub-pF/g is confirmed, which is hundreds of times higher compared to that of a sensor fabricated using the Parylene polymer (,r = 3.15). This sensitivity is an order higher compared to those of other reported capacitive microaccelerometers, which have comparable proof mass sizes and comparable detectable acceleration ranges to the newly fabricated sensor. Copyright © 2007 Institute of Electrical Engineers of Japan© 2007 Institute of Electrical Engineers of Japan. Published by John Wiley & Sons, Inc. [source]


Improved performance characteristics of the von Willebrand factor ristocetin cofactor activity assay using a novel automated assay protocol

JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Issue 10 2010
A. HILLARP
Summary.,Background, objectives and methods:,An accurate, sensitive and precise assay for reliable determination of the ristocetin cofactor activity of von Willebrand factor (VWF:RCo) in plasma and von Willebrand Factor (VWF)-containing concentrates has been evaluated. The assay is based on a commercially available automated protocol with modifications including a combination of adding additional ristocetin and the use of two calibration curves for the high and low measuring ranges. Results:,Addition of extra ristocetin resulted in improved measurement of VWF recoveries from various VWF-containing concentrates that were underestimated using the standard automated protocol. The modifications resulted in improved assay performance over an extended measuring range (2.00,0.03 IU mL,1). Accuracy was tested using VWF deficiency plasma spiked with the 1st international standard (IS) for VWF concentrate. Seven dilutions, ranging from 1.80 to 0.05 IU mL,1, were analyzed and resulted in measured concentrations between 80% and 100% of the assigned potency of the standard. Linearity was determined from the regression plot of the same concentrate dilutions and resulted in a correlation coefficient of 0.998. The repeatability, expressed as coefficient of variation, was 2% in the normal range (0.90 IU mL,1) and 8% at the level of 0.05 IU mL,1. The corresponding reproducibility results were 2% and 15% at the normal and low measuring ranges, respectively. Conclusions:,Analysis of patients with von Willebrand disease (VWD) indicates that the modified automated BCS® protocol has a superior discrimination power compared with the standard protocol. This is especially true in samples with low VWF, as in patients with type 3 VWD. [source]


Multi-sensor track-to-track fusion via linear minimum variance sense estimators

ASIAN JOURNAL OF CONTROL, Issue 3 2008
Li-Wei Fong
Abstract An integrated approach that consists of sensor-based filtering algorithms, local processors, and a global processor is employed to describe the distributed fusion problem when several sensors execute surveillance over a certain area. For the sensor tracking systems, each filtering algorithm utilized in the reference Cartesian coordinate system is presented for target tracking, with the radar measuring range, bearing, and elevation angle in the spherical coordinate system (SCS). For the local processors, each track-to-track fusion algorithm is used to merge two tracks representing the same target. The number of 2-combinations of a set with N distinct sensors is considered for central track fusion. For the global processor, the data fusion algorithms, simplified maximum likelihood (SML) estimator and covariance matching method (CMM), based on linear minimum variance (LMV) estimation fusion theory, are developed for use in a centralized track-to-track fusion situation. The resulting global fusers can be implemented in a parallel structure to facilitate estimation fusion calculation. Simulation results show that the proposed SML estimator has a more robust capability of improving tracking accuracy than the CMM and the LMV estimators. Copyright © 2008 John Wiley and Sons Asia Pte Ltd and Chinese Automatic Control Society [source]


Improved performance characteristics of the von Willebrand factor ristocetin cofactor activity assay using a novel automated assay protocol

JOURNAL OF THROMBOSIS AND HAEMOSTASIS, Issue 10 2010
A. HILLARP
Summary.,Background, objectives and methods:,An accurate, sensitive and precise assay for reliable determination of the ristocetin cofactor activity of von Willebrand factor (VWF:RCo) in plasma and von Willebrand Factor (VWF)-containing concentrates has been evaluated. The assay is based on a commercially available automated protocol with modifications including a combination of adding additional ristocetin and the use of two calibration curves for the high and low measuring ranges. Results:,Addition of extra ristocetin resulted in improved measurement of VWF recoveries from various VWF-containing concentrates that were underestimated using the standard automated protocol. The modifications resulted in improved assay performance over an extended measuring range (2.00,0.03 IU mL,1). Accuracy was tested using VWF deficiency plasma spiked with the 1st international standard (IS) for VWF concentrate. Seven dilutions, ranging from 1.80 to 0.05 IU mL,1, were analyzed and resulted in measured concentrations between 80% and 100% of the assigned potency of the standard. Linearity was determined from the regression plot of the same concentrate dilutions and resulted in a correlation coefficient of 0.998. The repeatability, expressed as coefficient of variation, was 2% in the normal range (0.90 IU mL,1) and 8% at the level of 0.05 IU mL,1. The corresponding reproducibility results were 2% and 15% at the normal and low measuring ranges, respectively. Conclusions:,Analysis of patients with von Willebrand disease (VWD) indicates that the modified automated BCS® protocol has a superior discrimination power compared with the standard protocol. This is especially true in samples with low VWF, as in patients with type 3 VWD. [source]