Home About us Contact
|
Home About us Contact | ||
|
|
||
Many Problems (many + problem)
Selected AbstractsSector Programme Approaches: Will They Work in Agriculture?DEVELOPMENT POLICY REVIEW, Issue 3 2001Mick Foster This article explores why sector-wide approaches, in which donor funds support a single sector plan under government leadership, have performed less well in agriculture than in the social sectors. Many problems stem from the more limited, more contested and shrinking role of the state in the agricultural sector. It is also argued that sector programmes have worked best where the key constraints on sector development are the responsibility of a single ministry, whereas agricultural development requires co-ordinated interventions across sectors. The sector approach may have a limited role in delivering better focused agricultural services, but fundamental policy questions need to be resolved first. This is more likely if support for reforms is channelled through central economic ministries and other bodies outside the agriculture ministry. [source] A dose,response perspective on college drinking and related problemsADDICTION, Issue 2 2010Paul J. Gruenewald ABSTRACT Aims In order to examine the degree to which heavy drinking contributes to risks for problems among college drinkers this paper develops and tests a dose,response model of alcohol use that relates frequencies of drinking specific quantities of alcohol to the incidence of drinking problems. Methods A mathematical model was developed that enabled estimation of dose,response relationships between drinking quantities and drinking problems using self-report data from 8698 college drinkers across 14 campuses in California, USA. The model assumes that drinking risks are a direct monotone function of the amount consumed per day and additive across drinking days. Drinking problems accumulate across drinking occasions and are the basis for cumulative reports of drinking problems reported by college drinkers. Results Statistical analyses using the model showed that drinking problems were related to every drinking level, but increased fivefold at three drinks and more gradually thereafter. Problems were associated most strongly with occasions on which three drinks were consumed, and more than half of all reported problems were related to occasions on which four or fewer drinks were consumed. There were some important differences in dose,responsiveness between men and women and between different groups of ,light', ,moderate' and ,heavier' drinkers. Conclusion Many problems among college students are associated with drinking relatively small amounts of alcohol (two to four drinks). Programs to reduce college drinking problems should emphasize risks associated with low drinking levels. [source] A Comparative Literature Survey of Islamic Finance and BankingFINANCIAL MARKETS, INSTITUTIONS & INSTRUMENTS, Issue 4 2001Tarek S. Zaher There has been large-scale growth in Islamic finance and banking in Muslim countries and around the world during the last twenty years. This growth is influenced by factors including the introduction of broad macroeconomic and structural reforms in financial systems, the liberalization of capital movements, privatization, the global integration of financial markets, and the introduction of innovative and new Islamic products. Islamic finance is now reaching new levels of sophistication. However, a complete Islamic financial system with its identifiable instruments and markets is still very much at an early stage of evolution. Many problems and challenges relating to Islamic instruments, financial markets, and regulations must be addressed and resolved. In this paper, we provide a comprehensive comparative review of the literature on the Islamic financial system. Specifically, we discuss the basic features of the Islamic finance and banking. We also introduce Islamic financial instruments in order to compare them to existing Western financial instruments and discuss the legal problems that investors in these instruments may encounter. The paper also gives a preliminary empirical assessment of the performance of Islamic banking and finance, and highlights the regulations, challenges and problems in the Islamic banking market. [source] The UCLan community engagement and service user support (Comensus) project: valuing authenticity, making space for emergenceHEALTH EXPECTATIONS, Issue 4 2007Soo Downe BA (Hons) RM MSc PhD Abstract Objective, To develop and evaluate service user, carer and community involvement in health and social care education. Background, Despite the high policy profile of involvement issues, there appear to be no published accounts of schemes that have used a systematic whole-faculty approach to community engagement in health and social care higher education. Focus of this paper, The set up and early development of a faculty-wide community engagement project. Setting and participants, Staff from the faculty of health in one University, local service users and carers and community group project workers and local National Health Service (NHS) and public sector staff. Design, Participatory action research including document review, field notes, questionnaires and interviews. Analysis, Thematic analysis. The emerging themes were tested by seeking disconfirming data, and through verification with stake-holders. Results, Prior to the study, there were examples of community engagement in the participating faculty, but they occurred in specific departments, and scored low on the ,ladder of involvement'. Some previous attempts at engagement were perceived to have failed, resulting in resistance from staff and the community. Despite this, an advisory group was successfully formed, and project framing and development evolved with all stake-holders over the subsequent year. The four themes identified in this phase were: building accessibility; being ,proper' service users/carers;moving from suspicion to trust: mutually respectful partnerships as a basis for sustainable change; and responses to challenge and emergence. Conclusions, Successful and sustainable engagement requires authenticity. Many problems and solutions arising from authentic engagement are emergent, and potentially challenging to organizations. [source] Health status impairment and costs associated with COPD exacerbation managed in hospitalINTERNATIONAL JOURNAL OF CLINICAL PRACTICE, Issue 7 2007J. F. O'Reilly Summary Exacerbations of chronic obstructive pulmonary disease (COPD) have serious health consequences for patients and are strongly associated with unscheduled healthcare resource use. This study used a preference-based quality of life measure questionnaire (EQ-5D) to evaluate the impact of exacerbation on health status and utility during a patient's admission to hospital and short-term follow-up. Costs of admission were calculated. In total, 149 patients consented to take part in the study representing 222 admissions to hospital. At admission patients reported high levels of problems for all dimensions of the EQ-5D. Mean utility (,0.077) and Visual Analogue Scale (25.9) values indicated great impairment, with 61% of patients having a negative utility value representing a health state equivalent to ,worse than death' at admission. Many problems were still reported at discharge. By 3 months follow-up patients had deteriorated, with percentages of patients reporting problems in mobility (98%) and usual activity (88%) almost back up to admission levels. Health status and utility values were similar regardless of lung function at admission and at discharge. Approximately half of the patients in each category had a negative utility value at admission representing a health state ,worse than death', with similar levels of improvement by discharge. The mean cost of an admission was £2130.34 (SD 1326.09) with only a mean of £110.37 (5%) because of medication. No differences were noted by lung function category. In conclusion, all COPD patients requiring admission for an exacerbation suffer a serious deterioration in health status which, although improves during admission, notably deteriorates by 3 months postdischarge. [source] Modular solvers for image restoration problems using the discrepancy principleNUMERICAL LINEAR ALGEBRA WITH APPLICATIONS, Issue 5 2002Peter Blomgren Abstract Many problems in image restoration can be formulated as either an unconstrained non-linear minimization problem, usually with a Tikhonov -like regularization, where the regularization parameter has to be determined; or as a fully constrained problem, where an estimate of the noise level, either the variance or the signal-to-noise ratio, is available. The formulations are mathematically equivalent. However, in practice, it is much easier to develop algorithms for the unconstrained problem, and not always obvious how to adapt such methods to solve the corresponding constrained problem. In this paper, we present a new method which can make use of any existing convergent method for the unconstrained problem to solve the constrained one. The new method is based on a Newton iteration applied to an extended system of non-linear equations, which couples the constraint and the regularized problem, but it does not require knowledge of the Jacobian of the irregularity functional. The existing solver is only used as a black box solver, which for a fixed regularization parameter returns an improved solution to the unconstrained minimization problem given an initial guess. The new modular solver enables us to easily solve the constrained image restoration problem; the solver automatically identifies the regularization parameter, during the iterative solution process. We present some numerical results. The results indicate that even in the worst case the constrained solver requires only about twice as much work as the unconstrained one, and in some instances the constrained solver can be even faster. Copyright © 2002 John Wiley & Sons, Ltd. [source] Reason for Visit: Is Migrant Health Care That Different?THE JOURNAL OF RURAL HEALTH, Issue 2 2008George F. Henning MD ABSTRACT:,Purpose:The purpose of this pilot study was to determine the reasons for which migrant agricultural workers in Pennsylvania seek health care.Methods:Participants were individuals 14 years of age and over, actively involved in agricultural labor and presenting for medical care at 6 migrant health care centers. Bilingual health care providers randomly selected and interviewed the participants.Findings:The most commonly reported reason for visiting the health care provider was for physical examination. The most frequent acute problems were related to the musculoskeletal and integumentary systems. Frequently cited problems in the medical history were hypertension, musculoskeletal/back pain, and gastrointestinal conditions. Most medications being taken were for cardiovascular or pain-related problems.Conclusions:These results suggest that migrant workers present with medical problems that are similar to those of the general primary care population. Many problems were recurrent and represented common chronic medical conditions. [source] Chemosensitivity of human pancreatic carcinoma cells is enhanced by IkB, super-repressorCANCER SCIENCE, Issue 5 2003Toshiyuki Sato Pancreatic cancer has an unfavorable prognosis; surgery and chemotherapy at present have only limited value. To improve the prognosis of pancreatic cancer, effective non-surgical therapy is necessary. NF- kB is reported to be related to resistance to apopto-sis, but its role in Chemosensitivity remains controversial. We examined the effects on Chemosensitivity of inhibition by induction of the super-repressor IkB, in pancreatic cancer cell lines, BxPC-3, Capan-1 and Panc-1. IkB, protein was transduced by infection of adenovirus vector AxCAhlkB,N. Sensitivity to VP-16 and doxorubicin was increased significantly by IkB, induction in all three pancreatic cell lines. To investigate molecular events during IkB, induction, we examined the changes in expression of drug-resistance-related genes by real-time RT-PCR and those in apoptosis-related genes by cDNA microarray. There was no common change of gene expression before and after IkB, induction among the three pancreatic cancer cell lines, except for mdm2. Further examination of other genes is necessary for a better understanding of the molecular mechanisms of enhancement of Chemosensitivity through IkB, induction. However, we have confirmed that IkB, induction leads to an increase of Chemosensitivity of pancreatic cancer. Many problems remain before clinical application of this adenoviral system will be feasible, but our results may ultimately lead to an improved therapy of pancreatic cancer. (Cancer Sci 2003; 94: 467,472) [source] Using parallelization and hardware concurrency to improve the performance of a genetic algorithmCONCURRENCY AND COMPUTATION: PRACTICE & EXPERIENCE, Issue 4 2007Vijay Tirumalai Abstract Genetic algorithms (GAs) are powerful tools for solving many problems requiring the search of a solution space having both local and global optima. The main drawback for GAs is the long execution time normally required for convergence to a solution. This paper discusses three different techniques that can be applied to GAs to improve overall execution time. A serial software implementation of a GA designed to solve a task scheduling problem is used as the basis for this research. The execution time of this implementation is then improved by exploiting the natural parallelism present in the algorithm using a multiprocessor. Additional performance improvements are provided by implementing the original serial software GA in dedicated reconfigurable hardware using a pipelined architecture. Finally, an advanced hardware implementation is presented in which both pipelining and duplicated hardware modules are used to provide additional concurrency leading to further performance improvements. Copyright © 2006 John Wiley & Sons, Ltd. [source] Evolution and persistence of the ciliumCYTOSKELETON, Issue 12 2007Peter Satir Abstract The origin of cilia, a fundamental eukaryotic organelle, not present in prokaryotes, poses many problems, including the origins of motility and sensory function, the origins of nine-fold symmetry, of basal bodies, and of transport and selective mechanisms involved in ciliogenesis. We propose the basis of ciliary origin to be a self-assembly RNA enveloped virus that contains unique tubulin and tektin precursors. The virus becomes the centriole and basal body, which would account for the self-assembly and self-replicative properties of these organelles, in contrast to previous proposals of spirochaete origin or endogenous differentiation, which do not readily account for the centriole or its properties. The viral envelope evolves into a sensory bud. The host cell supplies the transport machinery and molecular motors to construct the axoneme. Polymerization of cytoplasmic microtubules in the 9 + 0 axoneme completes the 9 + 2 pattern. Cell Motil. Cytoskeleton 2007. © 2007 Wiley-Liss, Inc. [source] A Stark Examination of Prison Culture and Prison MinistryDIALOG, Issue 3 2008R.N. Ristad Abstract:, This article offers an insightful examination of prison ministry from the inside, from someone who has been involved with this ministry for over forty-five years. The author discusses four major issues that are particularly costly, both in terms of personal human costs and also financial costs. First, society's misconceptions about prison violence, and the complex, varied ways prisoners experience violence. Second, the false sense of security the current practices of institutionalization create, and the consequences they have on the inmates. Third, the risk factors that can predispose children to ending up in prison, and the lack of care and attention those children often receive. And fourth, the way in which the criminalization of drug abuse has exacerbated many problems with the current prison system. The author concludes his article with some suggestions for reforming the prison system. [source] Adults with self-reported learning disabilities in Slovenia: Findings from the international adult literacy survey on the incidence and correlates of learning disabilities in SloveniaDYSLEXIA, Issue 4 2003Lidija Magajna This study of adults with self-reported learning disabilities (SRLD) in Slovenia is part of a larger secondary analysis of the data from the International Literacy Survey project (IALS). The purpose of the study was to examine the characteristics of 79 (2.68%) individuals who reported experiencing learning disabilities and compare them to the general population on a variety of indicators of educational background, employment status, and reading and writing activities at work and at home. The proficiency scores of the SRLD individuals were lower in all three literacy domains (prose, document and quantitative literacy). In prose literacy 77.9% of SRLD adults performed at Level 1 and only 7.8% reached the level necessary for a modern technological society. Experiencing learning disabilities was not related to gender or age, however, results showed significant differences between the levels achieved by older and younger people with SRLD. In SRLD groups aged 40 years and above, no one achieved more than the second level of literacy in any domain. Learning disabilities were reported more frequently in rural areas. SRLD groups achieve significantly lower educational attainment, and lower employment status, with a preference for manual labour or craft. These findings are of critical importance. SRLD people report that poorer literacy skills are an obstacle to their progression in employment. In the Slovene sample, the SRLD group stands out for low scores in quantitative literacy. Results show that they are less active, pick up information only auditorily or in short written form. They need more frequent help from relatives in literacy activities. Interpretation of the IALS data on SRLD presents many problems. These include amongst others, problems in terminology, different background factors, and the validity of self-report measures. However, the study also raises many interesting challenges for future research and policy. Increasing the availability of support, assistance and counselling for adolescents and adults with learning disabilities remains a very important goal for dyslexia and LD policies in Slovenia. Copyright © 2003 John Wiley & Sons, Ltd. [source] Relating information-needs to the cancer experience.EUROPEAN JOURNAL OF CANCER CARE, Issue 1 2000This paper is based on a phenomenological study that used narratives to explore lived cancer experiences. The aim of the study was to determine the important issues for people with cancer that arose out of their cancer experience, and to place their information-needs within the stages of the cancer trajectory. The literature highlights the importance of information-giving; however, many problems are encountered with its provision. People with cancer frequently express dissatisfaction with the information given to them and experience difficulty in retaining and processing information. Six individuals were invited to tell the story of their cancer experience through in-depth interviews and narrative analysis uncovered thematic aspects of the lived experience. One interview in particular stood out as capturing the essence of a lived experience. Jenny's narrative had a beginning, a middle and an end, features that are traditionally associated with stories. This paper focuses on her story in depth, and illustrates the extent to which cancer can impinge on normal coping mechanisms. A diagnosis of cancer cannot be isolated from the other events in an individual's life, and themes emerged which showed that cancer impacts on different aspects of an individual's self-identity, including body image, family, social and work relationships. The cancer experience invariably begins before the point of diagnosis and information-needs clearly change over time. [source] Development of an Improved Technique for the Perfusion of the Isolated Caudal Lobe of Sheep LiverEXPERIMENTAL PHYSIOLOGY, Issue 5 2000A. M. Ali The study was designed to develop an improved technique for perfusing the isolated caudal lobe of sheep liver. Twenty caudal lobes were perfused for 3-4 h, in a non-recirculating mode, with Krebs-Henseleit bicarbonate buffer. The perfusion system was designed to give a constant flow. The hepatic viability and functional normality of the perfused lobe were assessed by measuring the perfusion flow rate, pH, K+ efflux, O2 uptake, substrate uptake, gluconeogenesis from propionate and amino acids, and ureagenesis from ammonia and amino acids. Liver tissue was sampled for histological examination, as well as for the determination of liver glycogen and wet: dry weight ratio. The perfusion flow rate and pH were both stable throughout the perfusion. The potassium concentration in the effluent perfusate did not increase during the perfusion, suggesting that there was no loss of viability or hypoxia. The perfused lobe extracted more than 50% of the O2 supply. The rate of oxygen consumption was comparable to the rate reported in vivo. The initial glycogen content was reduced by about 40% after 4 h perfusion. The wet: dry weight ratio was 3.6, consistent with the absence of tissue oedema. Urea production was stimulated when NH4Cl (0.3 mM) was added to the medium but there was no significant increase in urea release when alanine (0.15 mM), glutamine (0.2 mM) or lysine (0.2 mM) was added. Urea production, however, increased by about 171% when a physiological mixture of amino acids was added. Propionate (0.5 mM), alanine and glutamine stimulated glucose production but not lysine or the complete amino acid mixture. Glutamine release was lower than that reported in the rat liver. Changing the direction of flow also revealed an apparent difference between livers from sheep and rats in their metabolism of ammonia. The improved technique offers a simple practical and inexpensive approach to many problems in ruminant physiology and nutritional biochemistry. [source] Memetic evolutionary training for recurrent neural networks: an application to time-series predictionEXPERT SYSTEMS, Issue 2 2006M. Delgado Abstract: Artificial neural networks are bio-inspired mathematical models that have been widely used to solve complex problems. The training of a neural network is an important issue to deal with, since traditional gradient-based algorithms become easily trapped in local optimal solutions, therefore increasing the time taken in the experimental step. This problem is greater in recurrent neural networks, where the gradient propagation across the recurrence makes the training difficult for long-term dependences. On the other hand, evolutionary algorithms are search and optimization techniques which have been proved to solve many problems effectively. In the case of recurrent neural networks, the training using evolutionary algorithms has provided promising results. In this work, we propose two hybrid evolutionary algorithms as an alternative to improve the training of dynamic recurrent neural networks. The experimental section makes a comparative study of the algorithms proposed, to train Elman recurrent neural networks in time-series prediction problems. [source] Analysis of microbial community functional diversity using sole-carbon-source utilisation profiles , a critiqueFEMS MICROBIOLOGY ECOLOGY, Issue 1 2002Juliet Preston-Mafham Abstract Information on functional diversity (metabolic potential) is essential for understanding the role of microbial communities in different environments. Variations of the commercially available BIOLOG bacterial identification system plates are now widely used to assess functional diversity of microorganisms from environmental samples, based on utilisation patterns of a wide range (up to 95) of single carbon sources. There are many problems as well as benefits of using the approach, but the former are often disregarded. Here the basis of the approach is summarised, including type of plate to use, treatment of samples, replication, incubation conditions, monitoring of plates, and statistical analysis. The pros and cons of its use are critically assessed, inherent biases and limitations are pointed out and methodological difficulties are considered. Possible ways of overcoming some of the difficulties are suggested. [source] MINIREVIEW: On the use of metaphor to understand, explain, or rationalize redundant genes in yeastFEMS YEAST RESEARCH, Issue 3 2008Stephen Cooper Abstract The proposal that yeast, and cells in general, contains redundant genes that enable cells to survive mutational change has been supported by experiments and a strong metaphor. The redundant gene proposal is analyzed, and it is noted that there are many problems with the redundant gene model. An alternative metaphor is suggested to explain the genetic composition of a yeast culture. [source] DIFFERENTIAL SUBURBAN DEVELOPMENT IN THE PRAGUE URBAN REGIONGEOGRAFISKA ANNALER SERIES B: HUMAN GEOGRAPHY, Issue 2 2007Martin Ou ABSTRACT. Numerous authors have asserted that suburbanization contributes to many problems in both suburban and inner city localities. Research of suburban development demonstrates variations in spatial patterns, the intensity of spatial processes, and the social and economic status of new suburbanites. While some forms of suburban development could cause serious problems throughout the urban region, other forms could be perceived as processes improving the quality of life in suburbia. This paper seeks to investigate different types of suburban development in the Prague urban region over the past fifteen years of transformation. The focus of my interest is residential suburbanization, which is one of the most significant spatial processes today in the settlement systems of post-socialist countries. The theoretical part of the contribution deals with the differentiation of spatial processes changing the suburban zone. Here I discuss the concepts of several processes of suburban development and their distinctive impact on both suburban and inner city localities. The empirical part of the contribution is based on an analysis of migration flows in the various localities of the Prague urban region in the period 1995 to 2003. I attempt to describe the magnitude and spatial patterns of suburbanization and the composition of migrants to suburbia. The paper concludes with a discussion about the possible future development of suburbanization in the Prague urban region. [source] Deliberation, Legitimacy, and Multilateral DemocracyGOVERNANCE, Issue 1 2003Loren A. King Is deliberation essential to legitimate democratic governance? Deliberation may have epistemic value, improving the quality of information and arguments. Deliberation may be transformative, shaping beliefs and opinions. Or deliberation may be part of a conception of justice that constrains authority, by requiring that procedures be justified in terms of reasons acceptable to those burdened by authoritative decisions. Although appealing, the epistemic and transformative arguments are limited by the scale and complexity of many problems for which democratic solutions are sought. But the reason,giving argument is persuasive whenever collective decisions allow burdens to be imposed on others. [source] Quantification of immunohistochemistry,issues concerning methods, utility and semiquantitative assessment IHISTOPATHOLOGY, Issue 4 2006R A Walker Immunohistochemistry is no longer a technique used only for research but is employed increasingly for diagnosis and for the assessment of therapeutic biomarkers. The latter, in particular, often require a semiquantitative evaluation of the extent of their presence. There are many factors that can affect this that relate to the method: fixation of tissue, duration and type of antigen retrieval, antibody specificity, antibody dilution and detection systems. Other complexities relate to assessment. Different scoring systems are used for either the same or different antigens. Cut-off levels for assessing whether a tissue is ,positive' or ,negative' can vary for the same antigen. Whilst there are quality assurance schemes for the methodology that have improved standards of staining, there are no similar schemes that relate to interpretation, although errors here can create as many problems. There have been improvements in automated analysis but availability is limited and it is still predominantly a research tool. In order for quantification of immunohistochemistry to be a reliable and reputable tool, there must be easy to use, reproducible, standardized protocols for assessment which are international. Improvements in automated analysis with wider applicability could lead to standardization. [source] Knowledge and Language: History, the Humanities, the SciencesHISTORY, Issue 285 2002Arthur Marwick Knowledge is not, as Marxisant post-modernists insist, mere ideology or expression of bourgeois power. The high standards enjoyed in the developed countries are fundamentally due to the expansion in human knowledge over the centuries. Decent living conditions, freedom and empowerment for the deprived millions everywhere depend upon the continuing expansion, and, above all, diffusion of knowledge. History is but one domain of knowledge among many, with its own autonomous methods and principles; though very different in detail, these are in spirit similar to those governing the natural sciences. There is a fundamental distinction between the domains of knowledge and the creative arts. ,Language' has a number of significations. In the most fundamental one, it is a human faculty which enables us to communicate, but which raises many problems for historians; none the less language does not control us: we can control language. Usages in foreign languages can often be revealing, while scientists have to master a special language, mathematics. Historians should be aware of other disciplines, and ready to borrow from them. There are many fascinating interdisciplinary problems to which historians can contribute, but these do not call for abstruse cultural theory; what they do call for is an extra-cool application of historical methodology. A case in point is that of the possible relationship between total war and the arts. Does total war affect artistic language or just content and philosophy? [source] Multichannel surface electromyography in ergonomics: Potentialities and limitsHUMAN FACTORS AND ERGONOMICS IN MANUFACTURING & SERVICE INDUSTRIES, Issue 4 2010Marco Gazzoni Abstract The prevention of work-related musculoskeletal disorders is one of the main goals in ergonomics. Among others, surface electromyography (sEMG) is an important tool for the evaluation of risks related to work activity. Three main issues have been approached in ergonomics via sEMG: 1) the analysis of muscle activation, 2) the analysis of exerted forces and torques, and 3) the analysis of muscle fatigue. Many studies have been carried out in static conditions. In ergonomics, however, it is more relevant to study muscle activity and fatigue during real tasks that are, in general, dynamic. From isometric to dynamic contractions, the complexity of the interpretation of sEMG signals increases considerably. Changes in sEMG signals are related to the continuous modifications in force output, muscle fiber length, and relative position of surface electrodes and sources. To increase the reliability of the information extracted from sEMG, multichannel detection systems have been applied, showing the possibility of overcoming some limits of the standard technique. Some illustrative laboratory and field studies are reported in this work to illustrate the potentialities and the open problems in the use of multichannel sEMG in ergonomics. Case 1 is a laboratory study investigating the myoelectric manifestations of fatigue in the biceps brachii (BB) during dynamic elbow flexion/extension. Case 2 is a laboratory study investigating the myoelectric manifestations of fatigue during a repetitive lifting task. Case 3 is a field study, carried out in an automotive plant, investigating muscle activation during the welding of a car door. Many factors play a leading role in the correct interpretation of information provided by sEMG. Even though multichannel sEMG provides information able to improve the estimation of force and/or fatigue during working tasks, many problems related to the signal acquisition and interpretation are still open. Further improvements are necessary to develop multichannel sEMG into an effective tool supporting other methodologies for the evaluation of work-related risks. © 2010 Wiley Periodicals, Inc. [source] Assessing the results of scenarios of climate and land use changes on the hydrology of an Italian catchment: modelling studyHYDROLOGICAL PROCESSES, Issue 19 2010Daniela R. D'Agostino Abstract Hydrological models are recognized as valid scientific tools to study water quantity and quality and provide support for the integrated management and planning of water resources at different scales. In common with many catchments in the Mediterranean, the study catchment has many problems such as the increasing gap between water demand and supply, water quality deterioration, scarcity of available data, lack of measurements and specific information. The application of hydrological models to investigate hydrological processes in this type of catchments is of particular relevance for water planning strategies to address the possible impact of climate and land use changes on water resources. The distributed catchment scale model (DiCaSM) was selected to study the impact of climate and land use changes on the hydrological cycle and the water balance components in the Apulia region, southern Italy, specifically in the Candelaro catchment (1780 km2). The results obtained from this investigation proved the ability of DiCaSM to quantify the different components of the catchment water balance and to successfully simulate the stream flows. In addition, the model was run with the climate change scenarios for southern Italy, i.e. reduced winter rainfall by 5,10%, reduced summer rainfall by 15,20%, winter temperature rise by 1·25,1·5 °C and summer temperature rise by 1·5,1·75 °C. The results indicated that by 2050, groundwater recharge in the Candelaro catchment would decrease by 21,31% and stream flows by 16,23%. The model results also showed that the projected durum wheat yield up to 2050 is likely to decrease between 2·2% and 10·4% due to the future reduction in rainfall and increase in temperature. In the current study, the reliability of the DiCaSM was assessed when applied to the Candelaro catchment; those parameters that may cause uncertainty in model output were investigated using a generalized likelihood uncertainty estimation (GLUE) methodology. The results showed that DiCaSM provided a small level of uncertainty and subsequently, a higher confidence level. Copyright © 2010 John Wiley & Sons, Ltd. [source] Semi-coupled air/water immersed boundary approach for curvilinear dynamic overset grids with application to ship hydrodynamicsINTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN FLUIDS, Issue 6 2008Juntao Huang Abstract For many problems in ship hydrodynamics, the effects of air flow on the water flow are negligible (the frequently called free surface conditions), but the air flow around the ship is still of interest. A method is presented where the water flow is decoupled from the air solution, but the air flow uses the unsteady water flow as a boundary condition. The authors call this a semi-coupled air/water flow approach. The method can be divided into two steps. At each time step the free surface water flow is computed first with a single-phase method assuming constant pressure and zero stress on the interface. The second step is to compute the air flow assuming the free surface as a moving immersed boundary (IB). The IB method developed for Cartesian grids (Annu. Rev. Fluid Mech. 2005; 37:239,261) is extended to curvilinear grids, where no-slip and continuity conditions are used to enforce velocity and pressure boundary conditions for the air flow. The forcing points close to the IB can be computed and corrected under a sharp interface condition, which makes the computation very stable. The overset implementation is similar to that of the single-phase solver (Comput. Fluids 2007; 36:1415,1433), with the difference that points in water are set as IB points even if they are fringe points. Pressure,velocity coupling through pressure implicit with splitting of operators or projection methods is used for water computations, and a projection method is used for the air. The method on each fluid is a single-phase method, thus avoiding ill-conditioned numerical systems caused by large differences of fluid properties between air and water. The computation is only slightly slower than the single-phase version, with complete absence of spurious velocity oscillations near the free surface, frequently present in fully coupled approaches. Validations are performed for laminar Couette flow over a wavy boundary by comparing with the analytical solution, and for the surface combatant model David Taylor Model Basin (DTMB) 5512 by comparing with Experimental Fluid Dynamics (EFD) and the results of two-phase level set computations. Complex flow computations are demonstrated for the ONR Tumblehome DTMB 5613 with superstructure subject to waves and wind, including 6DOF motions and broaching in SS7 irregular waves and wind. Copyright © 2008 John Wiley & Sons, Ltd. [source] Qualitative Analysis of Medicare Claims in the Last 3 Years of Life: A Pilot StudyJOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 1 2005Amber E. Barnato MD Objectives: To study end-of-life care of a representative sample of older people using qualitative interpretation of administrative claims by clinicians and to explore whether this method yields insights into patient care, including continuity, errors, and cause of death. Design: Random, stratified sampling of decedents and all their Medicare-covered healthcare claims in the 3 years before death from a 5% sample of elderly fee-for-service beneficiaries, condensation of all claims into a chronological clinical summary, and abstraction by two independent clinicians using a standardized form. Setting: United States. Participants: One hundred Medicare fee-for-service older people without disability or end-stage renal disease entitlement who died in 1996 to 1999 and had at least 36 months of continuous Part A and Part B enrollment before death. Measurements: Qualitative narrative of the patient's medical course; clinician assessment of care continuity and apparent medical errors; cause, trajectory, and place of death. Results: The qualitative narratives developed by the independent abstracters were highly concordant. Clinicians felt that 75% of cases lacked continuity of care that could have improved the quality of life and the way the person died, and 13% of cases had a medical error identified by both abstracters. Abstracters disagreed about assignment of a single cause of death in 28% of cases, and abstracters and the computer algorithm disagreed in 43% of cases. Conclusion: Qualitative claims analysis illuminated many problems in the care of chronically ill older people at the end of life and suggested that traditional vital statistics assignation of a single cause of death may distort policy priorities. This novel approach to claims review is feasible and deserves further study. [source] Hard-modelled trilinear decomposition (HTD) for an enhanced kinetic multicomponent analysisJOURNAL OF CHEMOMETRICS, Issue 5 2002Yorck-Michael Neuhold Abstract We present a novel approach for kinetic, spectral and chromatographic resolution of trilinear data sets acquired from slow chemical reaction processes via repeated chromatographic analysis with diode array detection. The method is based on fitting rate constants of distinct chemical model reactions (hard-modelled, integrated rate laws) by a Newton,Gauss,Levenberg/Marquardt (NGL/M) optimization in combination with principal component analysis (PCA) and/or evolving factor analysis (EFA), both known as powerful methods from bilinear data analysis. We call our method hard-modelled trilinear decomposition (HTD). Compared with classical bilinear hard-modelled kinetic data analysis, the additional chromatographic resolution leads to two major advantages: (1) the differentiation of indistinguishable rate laws, as they can occur in consecutive first-order reactions; and (2) the circumvention of many problems due to rank deficiencies in the kinetic concentration profiles. In this paper we present the theoretical background of the algorithm and discuss selected chemical rate laws. Copyright © 2002 John Wiley & Sons, Ltd. [source] Rehabilitation and guidance as reported by women and men who had undergone coronary bypass surgeryJOURNAL OF CLINICAL NURSING, Issue 4 2007Kirsi Koivunen RN Aims and objectives., The purpose of this study was to describe the experience of rehabilitation reported by coronary artery disease patients who had undergone coronary artery bypass surgery. A further purpose was to describe the kind of guidance on rehabilitation that they were given during this period. Methods., The data consisted of thematic questionnaires completed by six women and eight men who had undergone coronary artery bypass surgery. They had recorded their experiences on these questionnaires at one-month intervals for a year after the surgery. The data were analysed using the method of content analysis. Results., On the basis of the results, women had experienced the most balanced period of physical, mental and social rehabilitation during the six months following surgery. Their recovery, however, suffered a setback after the first six months. On the basis of the results, men attained a better balance of physical, mental and social rehabilitation only after the six-month period following surgery. Even men had various problems in their rehabilitation, but their recovery proceeded more smoothly than that of women. Women hoped for more guidance throughout the process of rehabilitation. The support and help from wives had a positive impact on the process of men's recovery. Peer support was another significant source support. Conclusions., A person undergoing rehabilitation needs special guidance from health care professionals, especially when his/her rehabilitation does not proceed optimally. The findings suggest that, especially, the guidance of women should be improved because women seemed to suffer from many problems during their process of rehabilitation, including loneliness, insecurity, uncertainty, fears, depression and anxiety. Relevance to clinical practice., Expanding the role of practical nurses to provide both preventive and rehabilitation guidance should be seen as an important strategy in health care. Individual needs, gender differences and support from families and peers should be taken into consideration when planning and implementing guidance. [source] 97 Sensitivity of cyanobacteria to a potential biological control agent, bacterium SG-3JOURNAL OF PHYCOLOGY, Issue 2003K. Wilkinson Cyanobacteria cause many problems in freshwater ecosystems. For example, the production of off-flavor compounds by cyanobacteria causes serious problems in catfish aquaculture. Control of cyanobacteria is generally limited to treatment with copper compounds, which are non-selective and sometimes ineffective at controlling certain species of cyanobacteria. Biological control could provide selective management by removing unwanted species while leaving desirable algae species. A bacterium (SG-3) (NRRL B-30043) lyses a number of planktonic species of cyanobacteria including bloom-forming species of Anabaena and Oscillatoria. We tested SG-3 for activity against 10 isolates, representing seven species, of mat-forming cyanobacteria within the genera Oscillatoria, Lyngbya, and Phormidium. Plugs (0.5 cm diameter) were cut from mats of the cyanobacterium, inoculated with liquid cultures of SG-3, and incubated as static cultures. The reduction in dry weights ranged from ,0.5% to 90% compared to the untreated controls and appeared to be species specific. For example, dry weight reductions of Oscillatoria deflexoides and O. amoena ranged from 80 to 90% whereas the reduction of O. limosa tended to be lower at 36 to 72%. Although results varied among and within species, they indicate that this bacterium could have potential for use as a biological control for mat-forming cyanobacteria. Light microscopic observations indicate the bacteria do not penetrate the cyanobacteria cells. Currently, we are studying the possible causes of the observed cell lysis. [source] Surveys for Beet Necrotic Yellow Vein Virus (the Cause of Rhizomania), other Viruses, and Soil-borne Fungi Infecting Sugar Beet in SyriaJOURNAL OF PHYTOPATHOLOGY, Issue 11-12 2002A. M. Mouhanna Abstract Production of sugar beet, the most important source of sugar in Syria, has suffered from many problems in the past, especially from diseases. No previous surveys have been made in Syria for viral diseases and soil-borne fungi of sugar beet. In 1998, samples were collected from plants showing symptoms of virus infection (yellowing, wilting, necrosis and mosaic). Root samples (341) were collected from crops of autumn-sown seed from 115 localities in seven provinces, 173 root samples from spring-sown crops and 39 leaf samples were collected during both seasons. The root samples were tested for the presence of viruses by double antibody sandwich-enzyme-linked immunosorbent assay (ELISA) and triple antibody sandwich-ELISA, and for soil-borne fungi by red plate (Rose Bengal) dishes. We have shown for the first time the presence of Beet necrotic yellow vein virus, Beet soil-borne virus, Beet yellows virus and Beet mild yellowing virus in Syrian sugar beet fields in which Rhizoctonia sp. and Fusarium sp. were also widely distributed. [source] The Supreme Court in the Nineteenth CenturyJOURNAL OF SUPREME COURT HISTORY, Issue 1 2002William H. Rehnquist At the beginning of the nineteenth century, we find a Court which has not yet found its role, and whose principal impact is deciding which litigant wins in a particular lawsuit. Chief Justice John Marshall, appointed in 1801, changes that; he and his successor, Roger B. Taney, are the dominant figures in the Courts over which they preside. From 1801 until 1864-sixty-three years-the nation had only two Chief Justices; during the same time, it had fifteen presidents. In the latter part of the nineteenth century, the Chief Justices are less dominant and influential, sharing their authority with several notable Associate Justices. By the end of the century, the Court is beginning to wrestle with the many problems facing the nation after a little more than a century of existence. [source] | |||||||||||||||||||||||||||||||||||||||||||||||||