Many Obstacles (many + obstacle)

Distribution by Scientific Domains


Selected Abstracts


Causes of blindness among hospital outpatients in Ecuador

CLINICAL & EXPERIMENTAL OPHTHALMOLOGY, Issue 2 2006
Helene Cass MB BS MPH
Abstract Background:, There is a lack of published information on the causes of blindness in Ecuador and the Latin American region in general. This study is designed to enumerate the proportions of ocular conditions contributing to blindness in an outpatient population of an ophthalmology hospital in the coastal region of Ecuador. Methods:, All cases presenting to an ophthalmology outpatient clinic over a 3-week period during September 2004 were reviewed (n = 802). Visual acuity was measured using a Snellen acuity chart and those who met the criteria for blindness were included in the study (n = 118). Blindness was defined under the World Health Organization protocol as visual acuity of <3/60. Both unilateral and bilateral blindness were included in the study. The diagnosis of ocular pathology contributing to blindness was recorded. Results:, Among those considered to have unilateral blindness (n = 88), cataract was the most common cause (43%). This was followed by corneal pathologies (17%) and glaucoma (15%). Among those considered to have bilateral blindness (n = 30), refraction was the most common cause (37%), followed by cataract (23%) and glaucoma (17%). Conclusion:, The major causes of blindness found in this study reflected those in estimated data for the region. More studies are needed to improve the quality and quantity of epidemiological data on blindness in Ecuador and Latin America. Many obstacles to successful implementation of prevention of blindness programmes in South America still need to be overcome. [source]


Synthesis, Structure, and Properties of Single-Walled Carbon Nanotubes

ADVANCED MATERIALS, Issue 45 2009
Weiya Zhou
Abstract Great interest in single-walled carbon nanotubes (SWCNTs) derives from their remarkable electrical, thermal, optical, and mechanical properties together with their lower density, which promise extensive and unique applications. Much progress has been achieved in the fundamental and applied investigations of SWCNTs over the past decade. At the same time, many obstacles still remain, hampering further development in this field. To clarify the emerging problems and to provide a comprehensive understanding of the field, we review the recent progress of research on the synthesis, structure, and properties of SWCNTs, in particular the SWCNT non-woven film, SWCNT rings, boron,nitrogen (B,N) co-doped SWCNTs (BCN-SWNTs), and individual SWCNTs. Some long-standing problems and topics warranting further investigations in the near future are addressed. [source]


Work redesign: Eight obstacles and opportunities

HUMAN RESOURCE MANAGEMENT, Issue 4 2005
Michael A. Campion
Successful work-design initiatives must overcome many obstacles in order to have their intended impact. This article outlines eight obstacles to work redesign: (1) influences on multiple outcomes, (2) trade-offs between different approaches, (3) difficulty in choosing appropriate units of analysis, (4) difficulty in predicting the nature of the job, (5) complications from individual differences, (6) job enlargement occurring without job enrichment, (7) creating new jobs as part of growth or downsizing, and (8) differences between longterm and short- term effects. This article examines the nature of these eight obstacles, reviews prior research on this topic, and outlines suggestions for managing these obstacles in practice. © 2005 Wiley Periodicals, Inc. [source]


Strategies for enhancing the adoption of school-based prevention programs: Lessons learned from the Blueprints for Violence Prevention replications of the Life Skills Training program

JOURNAL OF COMMUNITY PSYCHOLOGY, Issue 3 2003
Abigail A. Fagan
Widespread implementation of effective programs is unlikely to affect the incidence of violent crime unless there is careful attention given to the quality of implementation, including identification of the problems associated with the process of implementation and strategies for overcoming these obstacles. Here we describe the results of a process evaluation focused on discovering common implementation obstacles faced by schools implementing the Life Skills Training (LST) drug prevention program. The evaluation was conducted by the Center for the Study and Prevention of Violence (CSPV) under the Blueprints for Violence Prevention Initiative in conjunction with the designer of the LST program, Dr. Gilbert Botvin and his dissemination agency, National Health Promotion Associates (NHPA), and was funded by the Office of Juvenile Justice and Delinquency Prevention (OJJDP). This evaluation revealed that the 70 sites involved in the project faced many obstacles when implementing this science-based program in the "real" classroom setting, outside the rigorous controls of a research trial. Nonetheless, the schools were very successful in delivering the program in its entirety and with a high level of fidelity to the program model, and we attribute much of this success to the high level of independent monitoring provided by CSPV, as well as our ongoing efforts to work with schools to identify and overcome problems associated with implementation. © 2003 Wiley Periodicals, Inc. J Comm Psychol 31: 235,253, 2003. [source]


The challenge of using the low back pain guidelines: a qualitative research

JOURNAL OF EVALUATION IN CLINICAL PRACTICE, Issue 4 2007
Rachel Dahan MD MClSc
Abstract Purpose, Current low back pain (LBP) clinical guidelines have helped to summarize the scientific evidence and research, but have failed to provide tools and guide family physicians (FPs). The purpose of this study is to identify barriers and facilitators for the implementation of LBP guidelines from family FPs' perspective. Methods, A qualitative focus group study of FPs in the north of Israel. Purposeful sampling was used to recruit participants, all of them board-certified FPs. Four focus groups were created, and discussions were taped, transcribed and analysed for major themes. Results, Focus groups findings have expanded the understanding of the intellectual and mental challenges faced by Israeli FPs caring for LBP patients and highlighted the many obstacles to implementing LBP guidelines. Physicians' decision-making, pertaining to LBP, functions on three levels simultaneously: the physicians' agenda based on familiarity with the guidelines; their need to remain grounded in the context of the specific patient,doctor relationship; and the constraints and demands of the physician's workplace, medical system and environment. Conclusions, Despite an overall positive attitude towards LBP guideline implementation, FPs found it hard to come to terms with the conflicting dimensions of LBP patient care. The patient,doctor interaction determined the outcome of the encounter, whether it complied with the guidelines and whether the encounter leads to a healing process or to a vicious circle of unnecessary utilization of services. [source]


Promoting directional axon growth from neural progenitors grafted into the injured spinal cord

JOURNAL OF NEUROSCIENCE RESEARCH, Issue 6 2010
Joseph F. Bonner
Abstract Spinal cord injury (SCI) is a devastating condition characterized by disruption of axonal connections, failure of axonal regeneration, and loss of motor and sensory function. The therapeutic promise of neural stem cells has been focused on cell replacement, but many obstacles remain in obtaining neuronal integration following transplantation into the injured CNS. This study investigated the neurotransmitter identity and axonal growth potential of neural progenitors following grafting into adult rats with a dorsal column lesion. We found that using a combination of neuronal and glial restricted progenitors (NRP and GRP) produced graft-derived glutamatergic and GABAergic neurons within the injury site, with minimal axonal extension. Administration of brain-derived neurotrophic factor (BDNF) with the graft promoted modest axonal growth from grafted cells. In contrast, injecting a lentiviral vector expressing BDNF rostral into the injured area generated a neurotrophin gradient and promoted directional growth of axons for up to 9 mm. Animals injected with BDNF lentivirus (at 2.5 and 5.0 mm) showed significantly more axons and significantly longer axons than control animals injected with GFP lentivirus. However, only the 5.0-mm-BDNF group showed a preference for extension in the rostral direction. We concluded that NRP/GRP grafts can be used to produce excitatory and inhibitory neurons, and neurotrophin gradients can guide axonal growth from graft-derived neurons toward putative targets. Together they can serve as a building block for neuronal cell replacement of local circuits and formation of neuronal relays. © 2009 Wiley-Liss, Inc. [source]


Generating Peace: A Study of Nonformal Youth Organizations

PEACE & CHANGE, Issue 3 2003
Leonisa Ardizzone
Youth today encounter many obstacles,including poverty, violence, and marginalization,that often result in feelings of hopelessness and despair leading to harmful behaviors. This sometimes has led to the scapegoating of youth in society. However, many youth have chosen to confront these media-propagated stereotypes by becoming involved positively in their communities. Utilizing a conceptual framework and philosophy of education that incorporates structural violence theory and peace education pedagogy, this article explores the impact involvement has on inner-city youth who have chosen to address issues of direct and structural violence as peacebuilders. The empirical research conducted established that involvement in a prosocial organization had an impact on personal growth, on interest in learning, in a desire to "get their word out," and in reinforcing an ethic of social responsibility. This research supports the creation of bottom-up education programs that incorporate the voices of youth in their design and development. [source]


Performance Management, Evaluation and Learning in ,Modern' Local Government

PUBLIC ADMINISTRATION, Issue 2 2001
Ian Sanderson
Public sector reforms throughout OECD member states are producing a new model of ,public governance' embodying a more modest role for the state and a strong emphasis on performance management. In the UK, the development of performance management in the context of the ,new public management' has been primarily ,top-down' with a dominant concern for enhancing control and ,upwards account-ability' rather than promoting learning and improvement. The development of performance management and evaluation in local government in the UK has been conditioned by external pressures, especially reforms imposed by central government, which have encouraged an ,instrumental,managerial' focus on performance measurement. The new Labour government's programme of ,modernizing local government' places considerable emphasis on performance review and evaluation as a driver of continuous improvement in promoting Best Value. However, recent research has indicated that the capacity for evaluation in local government is uneven and many obstacles to evaluation exist in organizational cultures. Local authorities need to go beyond the development of review systems and processes to ensure that the capacity for evaluation and learning is embedded as an attribute of ,culture' in order to achieve the purpose of Best Value. [source]


On the Outskirts of Physics: Eva von Bahr as an Outsider Within in Early 20th Century Swedish Experimental Physics

CENTAURUS, Issue 1 2009
Staffan Wennerholm
Abstract Eva von Bahr (1874,1962) got her doctorate in experimental physics at the Physics Institute at Uppsala University in 1908. Subsequently she became the first woman assistant professor in physics in Sweden. In the face of many obstacles, she worked as a physicist for six years in Uppsala and Berlin. In 1914 she took a position as a school teacher. This article explores von Bahr's trajectory through academic experimental physics. It is argued that network connections with male scientists enabled her work. Her associations were a mix between institutional relationships and informal connections, resulting in what is labeled a ,hybrid of connections'. Furthermore it is argued that von Bahr became an ,outsider within' in academic experimental physics. Her connections created openings, but these coexisted with hindrances. It is argued that von Bahr oscillated between being an insider and an outsider which created a fractured identity. Her position and identity was a mix between membership and non-membership. Through examining von Bahr's career this article aims to bring together historical research on women in science and theoretical work in science studies. Furthermore, the article argues the analytical value of feminist perspectives on scientific collaborations as a way to a deeper understanding of the network structures of science. [source]