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Selected AbstractsWhat motivates men age , 50 years to participate in a screening program for melanoma?CANCER, Issue 4 2006Monika Janda PhD Abstract BACKGROUND. The screening behavior and screening outcomes of men age ,50 years was investigated within a randomized controlled trial of a community-based intervention of screening for melanoma, consisting of a community education program, an education program for medical practitioners, and the provision of dedicated skin-screening clinics. METHODS. Data from cross-sectional telephone surveys before (559 completed interviews), at the end (591 completed interview), and at 2 years after the intervention (445 completed interviews) were analyzed. In addition, the authors analyzed data from skin-screening clinics within the intervention program (3355 men age ,50 years participated). RESULTS. During the intervention period men age ,50 years increased both their screening behavior and intention to screen. Those men age ,50 years who reported a past history of removal of a mole as well as other risk factors for skin cancer and positive attitudes toward screening were more likely to participate in skin screening across time. Men age ,50 years accounted for 20.5% of all skin-screening clinic attendees, 31.3% of those referred for a suspicious lesion, 48.5% of melanomas, and 45% of all keratinocyte carcinomas diagnosed within the screening program, respectively. CONCLUSIONS. The intervention program successfully motivated men age ,50 years to attend screening for skin cancer, resulting in the highest yield of skin cancer within this subgroup of the population. Messages addressing skin cancer risk factors and attitudes toward skin cancer and screening could be used to target a screening program for melanoma toward men age ,50 years. Cancer 2006. © 2006 American Cancer Society. [source] A comparative, cross-national analysis of partner-killing by women in cohabiting and marital relationships in Australia and the United StatesAGGRESSIVE BEHAVIOR, Issue 3 2004Jenny Mouzos Abstract Using a national-level United States database, T. K. Shackelford [Partner-killing by women in cohabiting relationships and marital relationships. Homicide Studies 5: 253-266, 2001] calculated rates of partner-killing by women by relationship type (cohabiting or marital), by partner ages, and by the age difference between partners. Men in cohabiting relationships were 10 times more likely to be killed by their partners than were married men. Within marriages, the risk of being killed by a partner decreased with a man's age. Within cohabiting relationships, in contrast, middle-aged men were at greatest risk of being killed by their partners. The risk that a man will be killed by his partner generally increased with greater age difference between partners. We sought to replicate the findings of Shackelford [2001] using national-level data held as part of the National Homicide Monitoring Program (NHMP) at the Australian Institute of Criminology in Australia. The NHMP holds data on over 3,500 homicides that occurred in Australia between 1989 and 2000. Despite the higher rate of partner-killing in the United States, and despite other cultural differences between the two countries (for example, the prominent gun culture in the United States), we replicated the key patterns with the Australian data. Aggr. Behav. 30:206,216, 2004. © 2004 Wiley-Liss, Inc. [source] Envisioning Fatherhood: A Social Psychological Perspective on Young Men without Kids,FAMILY RELATIONS, Issue 2 2000William Marsiglio Using in-depth interviews and a purposive sample of 32 men ages 16,30 who have not yet fathered a child, our grounded theory study examined how men envision aspects of fatherhood. Informed by symbolic interactionist and life course perspectives, our interpretive data analyses yielded two interrelated substantive dimensions: fatherhood readiness and fathering visions. We introduce five interrelated theoretical themes to sharpen our understanding of these dimensions, and discuss how these dimensions and themes inform interventions aimed at heightening young men's procreative responsibility. [source] The Medical Interview: Differences Between Adult and Geriatric OutpatientsJOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 1 2001Sandeep Mann MD BACKGROUND: There is a perception that primary care physicians spend less time with older patients and little is known about physician and older patient satisfaction during clinical encounters. OBJECTIVE: To determine how primary care interviews of geriatric patients differ from those of other adults. DESIGN: Descriptive, analytic study. SETTING: Ten primary care sites in the United States and one in Canada, including public, voluntary, and private clinics and practices. PARTICIPANTS: Of the 544 patients, 45.6% were 65 and older and 17.8% were 75 or older. There were 127 participating physicians. MEASUREMENTS: Encounters were audiotaped and analyzed. Patients and physicians also completed exit questionnaires. RESULTS: Interview length increased significantly with age for men but not for women. Physician satisfaction did not change as patient age increased. Patient satisfaction, on the other hand decreased with age among women but not for men. Although physicians' and younger patients' perceptions of health were moderately associated, there was no association for men ages 75 and over. CONCLUSIONS: There is no evidence that physicians spend less time or are more uncomfortable with older patients. Both physician and male patient satisfaction remain stable with increasing patient age, despite greater disparity in patient and physician perceptions of health. Older female patients are less satisfied with physician visits than their younger counterparts, in the absence of changes in interview length or disparities between older female patients and their physicians in health perception. [source] Associations of 25 structural, degradative, and inflammatory candidate genes with lumbar disc desiccation, bulging, and height narrowingARTHRITIS & RHEUMATISM, Issue 2 2009Tapio Videman Objective To examine the allelic diversity of structural, inflammatory, and matrix-modifying gene candidates and their association with disc degeneration. Methods Subjects were 588 men ages 35,70 years. We investigated associations of single-nucleotide polymorphisms in AGC1 and in 12 collagen, 8 interleukin, and 4 matrix metalloproteinase genes with quantitative magnetic resonance imaging measurements of disc desiccation and disc bulging and height narrowing scores, after controlling for age and suspected risk factors. Analyses were performed using QTDT software. P values were derived from 1,000 permutations, and empirical P values for global significance also were applied. Results Twelve of the 99 variants in 25 selected candidate genes provided evidence of association (P < 0.05) with disc signal intensity in the upper and/or lower lumbar regions. Allelic variants of AGC1 (rs1042631; P = 0.001), COL1A1 (rs2075555; P = 0.005), COL9A1 (rs696990; P = 0.00008), and COL11A2 (rs2076311; P = 0.018) genes provided the most significant evidence of association with disc signal intensity. The same variants of AGC1 (P = 0.010) and COL9A1 (P = 0.014), as well as variants in the COL11A1 gene (rs1463035 [P = 0.004]; rs1337185 [P = 0.015]) were also associated with disc bulging, as was AGC1 with disc height narrowing (rs1516797; P = 0.005). In addition, 4 allelic variants in the immunologic candidate genes (rs2071375 in IL1A [P = 0.027]; rs1420100 in IL18RAP [P = 0.005]) were associated with disc signal intensity. Conclusion Genetic variants account for interindividual differences in disc matrix synthesis and degradation. The accuracy of the quantitative disc signal intensity measurements we used likely enhanced our ability to observe these associations. Our findings shed light on possible mechanisms of degeneration and support the view that disc degeneration is a polygenetic condition. [source] Prospective study of adiposity and weight change in relation to prostate cancer incidence and mortality,,CANCER, Issue 4 2007Margaret E. Wright PhD Abstract BACKGROUND. Adiposity has been linked inconsistently with prostate cancer, and few studies have evaluated whether such associations vary by disease aggressiveness. METHODS. The authors prospectively examined body mass index (BMI) and adult weight change in relation to prostate cancer incidence and mortality in 287,760 men ages 50 years to 71 years at enrollment (1995,1996) in the National Institutes of Health-AARP Diet and Health Study. At baseline, participants completed questionnaires regarding height, weight, and cancer screening practices, including digital rectal examinations and prostate-specific antigen tests. Cox regression analysis was used to calculate relative risks (RR) and 95% confidence intervals (95% CIs). RESULTS. In total, 9986 incident prostate cancers were identified during 5 years of follow-up, and 173 prostate cancer deaths were ascertained during 6 years of follow-up. In multivariate models, higher baseline BMI was associated with significantly reduced total prostate cancer incidence, largely because of the relationship with localized tumors (for men in the highest BMI category [,40 kg/m2] vs men in the lowest BMI category [<25 kg/m2]: RR, 0.67; 95% CI, 0.50,0.89; P = .0006). Conversely, a significant elevation in prostate cancer mortality was observed at higher BMI levels (BMI <25 kg/m2: RR, 1.0 [referent group]; BMI 25,29.9 kg/m2: RR, 1.25; 95% CI, 0.87,1.80; BMI 30,34.9 kg/m2: RR, 1.46; 95% CI, 0.92,2.33; and BMI ,35 kg/m2: RR, 2.12; 95% CI, 1.08,4.15; P = .02). Adult weight gain from age 18 years to baseline also was associated positively with fatal prostate cancer (P = .009), but not with incident disease. CONCLUSIONS. Although adiposity was not related positively to prostate cancer incidence, higher BMI and adult weight gain increased the risk of dying from prostate cancer. Cancer 2007. Published 2007 by the American Cancer Society. [source] |