			Home About us Contact

Main Advances (main + advance)

Distribution by Scientific Domains

Earth and Environmental Science	40%

Selected Abstracts

Rapid tunnel-valley formation beneath the receding Late Weichselian ice sheet in Vendsyssel, Denmark

BOREAS, Issue 4 2009
PETER B. E. SANDERSEN
Interpretation of Transient ElectroMagnetic (TEM) data and wire-line logs has led to the delineation of an intricate pattern of buried tunnel valleys, along with new evidence of glaciotectonically dislocated layers in recessional moraines in the central part of Vendsyssel, Denmark. The TEM data have been compared with recent results of stratigraphical investigations based on lithological and biostratigraphical analyses of borehole samples and dating with Optically Stimulated Luminescence (OSL) and radiocarbon. This has provided an overview of the spatial distribution of the late Quaternary lithostratigraphical formations, and the age of the tunnel valleys has been estimated. The tunnel valleys are typically 5,10 km long, 1 km wide and are locally eroded to depths of more than 180 m b.s.l. The valleys are interpreted to have been formed by subglacial meltwater erosion beneath the outermost part of the ice sheet during temporary standstills and minor re-advances during the overall Late Weichselian recession of the Scandinavian Ice Sheet. The formation of the tunnel valleys occurred after the retreat of the Main ice advance c. 20 kyr BP and before the Lateglacial marine inundation c. 18 kyr BP. Based on the occurrence of the tunnel valleys and the topography, four ice-marginal positions related to the recession of the northeastern Main advance and seven ice-marginal positions related to the recession from the following eastern re-advance across Vendsyssel are delineated. All the tunnel valleys were formed within a time interval of a few thousand years, giving only a few hundred years or less for the formation of the tunnel valleys at each ice-marginal position. [source]

Two decades of urban climate research: a review of turbulence, exchanges of energy and water, and the urban heat island

INTERNATIONAL JOURNAL OF CLIMATOLOGY, Issue 1 2003
A. John Arnfield
Abstract Progress in urban climatology over the two decades since the first publication of the International Journal of Climatology is reviewed. It is emphasized that urban climatology during this period has benefited from conceptual advances made in microclimatology and boundary-layer climatology in general. The role of scale, heterogeneity, dynamic source areas for turbulent fluxes and the complexity introduced by the roughness sublayer over the tall, rigid roughness elements of cities is described. The diversity of urban heat islands, depending on the medium sensed and the sensing technique, is explained. The review focuses on two areas within urban climatology. First, it assesses advances in the study of selected urban climatic processes relating to urban atmospheric turbulence (including surface roughness) and exchange processes for energy and water, at scales of consideration ranging from individual facets of the urban environment, through streets and city blocks to neighbourhoods. Second, it explores the literature on the urban temperature field. The state of knowledge about urban heat islands around 1980 is described and work since then is assessed in terms of similarities to and contrasts with that situation. Finally, the main advances are summarized and recommendations for urban climate work in the future are made. Copyright © 2003 Royal Meteorological Society. [source]

Small Area Estimation-New Developments and Directions

INTERNATIONAL STATISTICAL REVIEW, Issue 1 2002
Danny Pfeffermann
Summary The purpose of this paper is to provide a critical review of the main advances in small area estimation (SAE) methods in recent years. We also discuss some of the earlier developments, which serve as a necessary background for the new studies. The review focuses on model dependent methods with special emphasis on point prediction of the target area quantities, and mean square error assessments. The new models considered are models used for discrete measurements, time series models and models that arise under informative sampling. The possible gains from modeling the correlations among small area random effects used to represent the unexplained variation of the small area target quantities are examined. For review and appraisal of the earlier methods used for SAE, see Ghosh & Rao (1994). [source]

Macromolecular structure determination by cryo-electron microscopy

ACTA CRYSTALLOGRAPHICA SECTION D, Issue 10 2000
Helen R. Saibil
Recent advances in transmission electron microscopy (EM) hardware, low-temperature methods and image-processing software have made cryo-EM an important complement to X-ray crystallography and NMR for macromolecular structure determination, particularly of large assemblies. This review provides a summary of the main advances and a survey of the capabilities of this approach. [source]

Kinin B1 receptors: key G-protein-coupled receptors and their role in inflammatory and painful processes

BRITISH JOURNAL OF PHARMACOLOGY, Issue 7 2004
João B Calixto
Kinins are a family of peptides implicated in several pathophysiological events. Most of their effects are likely mediated by the activation of two G-protein-coupled receptors: B1 and B2. Whereas B2 receptors are constitutive entities, B1 receptors behave as key inducible molecules that may be upregulated under some special circumstances. In this context, several recent reports have investigated the importance of B1 receptor activation in certain disease models. Furthermore, research on B1 receptors in the last years has been mainly focused in determining the mechanisms and pathways involved in the process of induction. This was essentially favoured by the advances obtained in molecular biology studies, as well as in the design of selective and stable peptide and nonpeptide kinin B1 receptor antagonists. Likewise, development of kinin B1 receptor knockout mice greatly helped to extend the evidence about the relevance of B1 receptors during pathological states. In the present review, we attempted to remark the main advances achieved in the last 5 years about the participation of kinin B1 receptors in painful and inflammatory disorders. We have also aimed to point out some groups of chronic diseases, such as diabetes, arthritis, cancer or neuropathic pain, in which the strategic development of nonpeptidic oral-available and selective B1 receptor antagonists could have a potential relevant therapeutic interest. British Journal of Pharmacology (2004) 143, 803,818. doi:10.1038/sj.bjp.0706012 [source]