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Maxillofacial Region (maxillofacial + region)
Selected AbstractsBisphosphonate-Associated Osteonecrosis of the Jaw: Report of a Task Force of the American Society for Bone and Mineral Research,,JOURNAL OF BONE AND MINERAL RESEARCH, Issue 10 2007Sundeep Khosla (Chair) Abstract ONJ has been increasingly suspected to be a potential complication of bisphosphonate therapy in recent years. Thus, the ASBMR leadership appointed a multidisciplinary task force to address key questions related to case definition, epidemiology, risk factors, diagnostic imaging, clinical management, and future areas for research related to the disorder. This report summarizes the findings and recommendations of the task force. Introduction: The increasing recognition that use of bisphosphonates may be associated with osteonecrosis of the jaw (ONJ) led the leadership of the American Society for Bone and Mineral Research (ASBMR) to appoint a task force to address a number of key questions related to this disorder. Materials and Methods: A multidisciplinary expert group reviewed all pertinent published data on bisphosphonate-associated ONJ. Food and Drug Administration drug adverse event reports were also reviewed. Results and Conclusions: A case definition was developed so that subsequent studies could report on the same condition. The task force defined ONJ as the presence of exposed bone in the maxillofacial region that did not heal within 8 wk after identification by a health care provider. Based on review of both published and unpublished data, the risk of ONJ associated with oral bisphosphonate therapy for osteoporosis seems to be low, estimated between 1 in 10,000 and <1 in 100,000 patient-treatment years. However, the task force recognized that information on incidence of ONJ is rapidly evolving and that the true incidence may be higher. The risk of ONJ in patients with cancer treated with high doses of intravenous bisphosphonates is clearly higher, in the range of 1,10 per 100 patients (depending on duration of therapy). In the future, improved diagnostic imaging modalities, such as optical coherence tomography or MRI combined with contrast agents and the manipulation of image planes, may identify patients at preclinical or early stages of the disease. Management is largely supportive. A research agenda aimed at filling the considerable gaps in knowledge regarding this disorder was also outlined. [source] Short-term changes in temporomandibular joint function in subjects with cleft lip and palate treated with maxillary distraction osteogenesisORTHODONTICS & CRANIOFACIAL RESEARCH, Issue 2 2008K Hashimoto Structured Abstract Authors,,, Hashimoto K, Otsuka R, Minato A, Sato-Wakabayashi M, Takada J, Inoue-Arai MS, Miyamoto JJ, Ono T, Ohyama K, Moriyama K Objectives,,, To investigate the short-term effects of maxillary distraction osteogenesis (DO) on temporomandibular joint (TMJ) function in 21 subjects with cleft lip and palate (CLP). Design,,, Morphological changes in the maxillofacial region were measured using lateral cephalometric radiographs taken immediately before (pre-DO) and after DO (post-DO) and 1 year after DO (1-year follow-up). A questionnaire was evaluated using a visual analog scale. A chi-square test was used to compare the prevalence of TMJ symptoms between pre-DO and 1-year follow-up. The Spearman correlation coefficient was used to determine the correlation between changes in cephalometric variables and TMJ symptoms in association with maxillary DO. Statistical significance was set at p < 0.05. Results,,, The ANB (anteroposterior relationship of the maxilla with the mandible) angle and the mandibular plane angle at pre-DO, post-DO, and 1-year follow-up were ,4.3°, +5.8°, +4.3° and 32.1°, 33.5°, 33.6°, respectively. The average amounts of anterior and downward movement of the maxilla at post-DO and 1-year follow-up were 8.3, ,1.3 and 0.9, 1.1 mm, respectively. The prevalence of TMJ symptoms showed no significant increase in association with maxillary DO. Moreover, there was no significant correlation between changes in cephalometric variables and TMJ symptoms. Conclusion,,, These results suggest that there was no short-term (i.e., up to 1 year after DO) effect of maxillary DO on TMJ function in subjects with CLP. [source] Cone-beam computed tomography of the maxillofacial region,an updateTHE INTERNATIONAL JOURNAL OF MEDICAL ROBOTICS AND COMPUTER ASSISTED SURGERY, Issue 4 2009Chung How Kau Abstract Background During the last few years, craniomaxillofacial diagnosis of the head has been confronted with an increasing number of innovations and improvements. The main progress occurred following the introduction of cone-beam technology in computed tomography in the 1990s. The number of manufacturers and devices using this technology for the maxillofacial region is growing rapidly and they are now becoming readily available. Materials This article focuses on cone-beam computed tomography (CBCT) devices applied to the maxillofacial region. CBCT serves as a bridge from two dimensions (2D) to three dimensions (3D), with lower irradiation than conventional CT. Different manufacturers and models are now available to satisfy the different needs of clinicians. Results A recent review of the manufacturers found 23 CBCT devices on the market. The specifications, applications and other issues of currently available CBCT devices are presented and discussed. Conclusions 3D imaging is developing at a very fast pace. New technologies and machines are emerging and CBCT is becoming readily available. Due to the growing demand for the technology based on the needs of clinicians, there is now a wide and growing selection of devices on the market. Some of the new advances now mean that CBCT imaging should be a well-considered option in maxillofacial imaging. Copyright © 2009 John Wiley & Sons, Ltd. [source] Repair of the trigeminal nerve: a reviewAUSTRALIAN DENTAL JOURNAL, Issue 2 2010RHB Jones Abstract Nerve surgery in the maxillofacial region is confined to the trigeminal and facial nerves and their branches. The trigeminal nerve can be damaged as a result of trauma, local anaesthesia, tumour removal and implant placement but the most common cause relates to the removal of teeth, particularly the inferior alveolar and lingual nerves following third molar surgery. The timing of nerve repair is controversial but it is generally accepted that primary repair at the time of injury is the best time to repair the nerve but it is often a closed injury and the operator does not know the nerve is injured until after the operation. Early secondary repair at about three months after injury is the most accepted time frame for repair. However, it is also thought that a reasonable result can be obtained at a later time. It is also generally accepted that the best results will be obtained with a direct anastamosis of the two ends of the nerve to be repaired. However, if there is a gap between the two ends, a nerve graft will be required to bridge the gap as the two ends of the nerve will not be approximated without tension and a passive repair is important for the regenerating axons to grow down the appropriate perineural tubes. Various materials have been used for grafting and include autologous grafts, such as the sural and greater auricular nerves, vein grafts, which act as a conduit for the axons to grow down, and allografts such as Neurotube, which is made of polyglycolic acid (PGA) and will resorb over a period of time. [source] | ||||||||||