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Male Excess (male + excess)
Selected AbstractsAn international perspective on Tourette syndrome: selected findings from 3500 individuals in 22 countriesDEVELOPMENTAL MEDICINE & CHILD NEUROLOGY, Issue 7 2000Roger D Freeman MD We have established a multisite, international database of 3500 individuals diagnosed with Tourette syndrome (TS). The male:female ratio is 4.3:1 for the total sample, with wide variation among sites; the male excess occurs at every site. Anger control problems, sleep difficulties, coprolalia, and self-injurious behavior only reach impressive levels in individuals with comorbidity. Anger control problems are strongly correlated with comorbidity, regardless of site, region, or whether assessed by neurologists or psychiatrists. The mean age at onset of tics is 6.4 years. At all ages, about 12% of individuals with TS have no reported comorbidity. The most common reported comorbidity is attention-deficit-hyperactivity disorder. Males are more likely to have comorbid disorders than females. The earlier the age at onset, the greater the likelihood of a positive family history of tics. An understanding of the factors producing these and other variations might assist in better subtyping of TS. Because behavioral problems are associated with comorbidity, their presence should dictate a high index of suspicion of the latter, whose treatment may be at least as important as tic reduction. The established database can be used as the entry point for further research when large samples are studied and generalizability of results is important. [source] The effect of smoking on the male excess of bladder cancer: A meta-analysis and geographical analysesINTERNATIONAL JOURNAL OF CANCER, Issue 2 2009Marjolein Hemelt Abstract Smoking is considered the primary risk factor for bladder cancer. Although smoking prevalence and bladder cancer incidence vary around the world, bladder cancer is on average 4 times more common in males than in females. This article describes the observed male,female incidence ratio of bladder cancer for 21 world regions in 2002 and 11 geographical areas during the time period 1970,1997. A meta-analysis, including 34 studies, was performed to ascertain the increased risk for bladder cancer in males and females when smoking. The summary odds ratios (SORs) calculated in the meta-analysis were used to estimate the male,female incidence ratio of bladder cancer that would be expected for hypothetical smoking prevalence scenarios. These expected male,female incidence ratios were compared with the observed ratios to evaluate the role of smoking on the male excess of bladder cancer. The male,female incidence ratio of bladder cancer was higher than expected worldwide and over time, based on a smoking prevalence of 75% in males, 10% in females and an increased risk (SOR) of bladder cancer associated with smoking of 4.23 for males and 1.35 for females, respectively. This implied that, at least in the Western world, smoking can only partially explain the difference in bladder cancer incidence. Consequently, other factors are responsible for the difference in bladder cancer incidence. © 2008 Wiley-Liss, Inc. [source] Morbidity figures from general practice: sex differences in traumatologyJOURNAL OF EVALUATION IN CLINICAL PRACTICE, Issue 4 2010Toine Lagro-Janssen MD PhD Abstract Background, Trauma prevention starts with to find out the extent of the problem and who it affects. Insight into morbidity figures is therefore necessary. Aim, To explore sex differences in traumatology and secondary medical care utilization in primary care related to age and socio-economic status (SES). Methods, Data were obtained from an academic continuous morbidity registration project in the Netherlands in the period from 1996 to 2006, in which 13 000 patients were followed in 10 successive years. Results, Sex differences showed a male excess from childhood to 45 years and women showing almost double trauma rates in the elderly. Low SES was associated with the greatest incidence of traumas. The largest sex difference in incidence above 65 years appeared in the high SES with more traumas in women compared with men. From this age on, female morbidity in traumatology outnumbered male morbidity regardless of SES. Considering use of referrals, we found that in the age group 15,45 years men made a greater use of secondary medical care. However, the vastest gender influence in medical care utilization was noticed in the age group over 65 years, outnumbered with women. Conclusion, Young men and old women are the most at risk for traumatic health problems: men presenting with traumata of the skull, the tibia and ocular trauma's and women with fractures of the femur, humerus and wrist. For both men and women the greatest incidence is in the low SES. Family physicians can play a pivotal role in prevention to focus on their patients with high risks. [source] | ||||||||||