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MNCs
Selected AbstractsCorporate social reporting for different audiences: the case of multinational corporations in SpainCORPORATE SOCIAL RESPONSIBILITY AND ENVIRONMENTAL MANAGEMENT, Issue 5 2010Ladislao Luna Sotorrío Abstract The objective of this research is twofold: first, to analyze descriptively the type of social information disclosed and the degree to which multinational corporations (MNCs) disclose it, and second, to empirically test whether there are differences in the reporting policy of this type of company according to the audience (global or local), and to discover the factors that explain these differences. A sample of 26 non-Spanish MNCs operating in Spain was selected from the Spanish Merco reputation index in the period 2004,2007. The results show that there are very significant differences in the degree of disclosure and the type of social information reported by MNCs for each audience, and that a company's visibility and resources, in this order, are relevant factors in explaining these differences. Copyright © 2009 John Wiley & Sons, Ltd and ERP Environment. [source] Corporate social responsibility in host countries: a perspective from American managersCORPORATE SOCIAL RESPONSIBILITY AND ENVIRONMENTAL MANAGEMENT, Issue 1 2007Robert L. Engle Abstract This paper examines the beliefs of 56 US-based senior international business executives regarding the importance of multinational corporations' involvement in the improvement of host countries' human rights, poverty, education, health care and environment. The results of this pilot study suggest that all five areas are considered important, with the environmental responsibilities of MNCs being perceived as the most important of these five areas. Little significant difference was found with regards to the executives' views of importance based on either their having lived overseas or based on the international component of their current job activity, with one exception: those executives with more than 50% of their job involving international activities believed that MNCs had a significantly greater environmental responsibility in host countries than did those with less job-related international activity. Copyright © 2006 John Wiley & Sons, Ltd and ERP Environment. [source] Multinational Corporations and Patterns of Local Knowledge Transfer in Costa Rican High-Tech IndustriesDEVELOPMENT AND CHANGE, Issue 3 2008Elisa Giuliani ABSTRACT Over recent decades, governments in industrializing countries have promoted policies to attract foreign investors, anticipating the benefits of technology transfer to host economies. During the 1990s, Costa Rica adopted an industrialization strategy based on attracting high-tech multinational companies (MNCs). Using an original survey of a sample of high-tech MNC subsidiaries, this article shows that the new wave of efficiency-seeking subsidiaries tend not to transfer knowledge to domestic firms even when they establish backward linkages with them. Instead, most of the knowledge transfer occurs between high-tech foreign subsidiaries. This has clear policy implications for host country governments. [source] Dose- and time-dependent responses for micronucleus induction by X-rays and fast neutrons in gill cells of medaka (Oryzias latipes)ENVIRONMENTAL AND MOLECULAR MUTAGENESIS, Issue 2 2004Akinori Takai Abstract Medaka fish (Oryzias latipes) were exposed to various doses of X-rays or fast neutrons, and the frequency of micronucleated cells (MNCs) was measured in gills sampled at 12- or 24-hr intervals from 12 to 96 hr after exposure. The resulting time course of MNC frequency was biphasic, with a clear peak 24 hr after exposure, irrespective of the kind of radiation applied and the dose used. The half-life of MNCs induced in the gill tissues by the two exposures fluctuated around 28 hr, with no significant dose-dependent trend for either X-ray- or neutron-exposed fish. As assayed 24 hr after exposure, the MNC frequency increased linearly over the control level with increasing doses of both X-rays and fast neutrons. The relative biological effectiveness (RBE) of fast neutrons to X-rays for MNC induction was estimated to be 4.3 ± 0.6. This value is close to the RBE value of 5.1 ± 0.3 reported for fast neutron induction of somatic crossing-over mutations in Drosophila melanogaster that arise from recombination repair of DNA double-strand breaks. These results and other data support our conclusion that the medaka gill cell micronucleus assay is a reliable short-term test for detecting potential inducers of DNA double-strand breaks. Environ. Mol. Mutagen. 44:108,112, 2004. © 2004 Wiley-Liss, Inc. [source] Context-bound configurations of corporate HR functions in multinational corporationsHUMAN RESOURCE MANAGEMENT, Issue 1 2010Elaine Farndale Abstract Considerable attention has focused on how multinational corporations (MNCs) deal with the simultaneous pressures of globalization and localization when it comes to human resource management (HRM). HR function activities in this process, however, have received less focus. The study presented here identifies configurations of the corporate HR function based on international HRM (IHRM) structures, exploring how issues of interdependency shape corporate HR roles. The study is based on 248 interviews in 16 MNCs based in 19 countries. The findings are applied to develop a contextually based framework outlining the main corporate HR function configurations in MNCs, including new insights into methods of IHRM practice design. © 2010 Wiley Periodicals, Inc. [source] Convergence in human resource systems: A comparison of locally owned and MNC subsidiaries in TaiwanHUMAN RESOURCE MANAGEMENT, Issue 3 2005Shyh-Jer Chen This article investigates issues of convergence in human resource systems in Taiwan, with reference to the similarities and differences between locally owned companies and subsidiaries of multinational corporations (MNCs). Traditionally, management in Taiwanese companies has been largely influenced by Confucian values and is quite distinct from approaches common to MNCs. However, globalization has engendered significant competitive pressures, coupled with cultural and institutional change within Taiwan. This article provides a theoretical framework for understanding such changes and provides empirical evidence indicating that Taiwanese companies are acting very much like MNCs with regard to the adoption of flexible, highperformance work systems. © 2005 Wiley Periodicals, Inc. [source] Foreign subsidiary perspectives on the mechanisms of global HRM integrationHUMAN RESOURCE MANAGEMENT JOURNAL, Issue 2 2008Adam Smale Often in connection with the integration-responsiveness dilemma, research on HRM in multinational corporations (MNCs) speaks more to explaining the appearance of HRM practices in foreign subsidiaries than to the mechanisms through which such practices are globally integrated. Accordingly, and adopting a subsidiary perspective, the present study has two main aims. The first is to identify the key mechanisms of global HRM integration, how they are used and by whom, and the second is to investigate the factors that explain their usage. The study uses qualitative data from 40 personal interviews conducted with general managers and the most senior HR personnel across 20 Finnish-owned subsidiaries in China. Based on the contingency view of organisations, explanations for mechanism usage are attributed to certain internal characteristics of the subsidiaries and to the Chinese institutional environment. [source] Transferring HR practices within multinational corporationsHUMAN RESOURCE MANAGEMENT JOURNAL, Issue 4 2007Ingmar Björkman There is extensive evidence that planned transfers of management practices by the headquarters of multinational corporations (MNCs) to foreign subsidiaries are not always successful. In this article, we outline a model of factors influencing the transfer of HR practices to MNC units abroad. The article has two main contributions. First, we develop a more holistic understanding of the outcome of HR practice transfer as encompassing three dimensions: implementation, internalisation and integration. Second, we expand current explanations of transfers of practices to foreign units. We argue that transfer of HR practices is a social process where the governance mechanisms used by the MNC, characteristics of the subsidiary HR systems, the social relationship between the subsidiary and MNC headquarters, and the transfer approach taken by headquarters management will influence the outcome of the process. [source] Creating social capital in MNCs: the international human resource management challengeHUMAN RESOURCE MANAGEMENT JOURNAL, Issue 4 2007Sully Taylor Social capital has assumed a critical role in the successful implementation of global strategy for multinational companies (MNCs). The article focuses on the ways in which the international human resource management (IHRM) system and those responsible for it influence the creation and utilisation of social capital in MNCs. It examines the challenges posed to IHRM by the wide diversity of definitions and manifestations of social capital found in the multiple cultural contexts of the global business environment and provides a framework on how to approach the cultural influences on the definitions and behavioural expressions of social capital. It also critically assesses the recommendations that have been made regarding developing social capital in MNCs, the competencies most critical to the ability to develop social capital in multiple cultural settings, and provides a set of recommendations for future research in this area. [source] Foreign firms in China: modelling HRM in a toy manufacturing corporationHUMAN RESOURCE MANAGEMENT JOURNAL, Issue 3 2004Fang Lee Cooke This article reports the study of a large, wholly foreign-owned toy factory in China. It explores whether foreign direct investment (FDI) manufacturing firms in China inevitably operate in a Taylorist fashion, in contrast to the much praised HR model of blue chip multinational corporations (MNCs) in the country, or whether there is a ,third way' in which good HR practices may be adopted on the ground. The article concludes that a more nuanced approach is needed in our study of FDI companies in order to gain a fuller understanding of the institutional and cultural factors at play and of the consequent diversity in the HR and employment practices of FDI firms, instead of being trapped in a simplistic and polarising typological framework of analysis. This study is necessary in light of the growing diversity in the patterns of FDI companies operating in China in terms of their ownership structure, product market, management style and HR strategy, both for managers and for workers. [source] HRD in multinationals: the global/local mixHUMAN RESOURCE MANAGEMENT JOURNAL, Issue 2 2001Olga Tregaskis This article is concerned with how MNCs (multinational corporations) differ from indigenous organisations in relation to their human resource development (HRD) practices, and whether this relationship changes across countries. We question whether local isomorphism is apparent in the HRD practices of MNCs, or whether MNCs share more in common with their counterparts in other countries. A series of hypotheses are put forward and tested, using survey data from 424 multinational and 259 indigenous organisations based in the UK and Ireland. The results suggest a hybrid form of localisation, where MNCs adapt their practices to accommodate national differences, but that these adaptations do not reflect convergence to domestic practice. The results also indicate that MNCs are selective in the HRD practices that are adapted. Evidence from this study indicates that country differences in career traditions and labour market skill needs are key drivers in the localisation of associated HRD practice. In contrast, MNCs, irrespective of national context, adopt comparable systematic training frameworks, ie training-need identification, evaluation and delivery. [source] T helper cell type 1 (Th1), Th2 and Th17 responses to myelin basic protein and disease activity in multiple sclerosisIMMUNOLOGY, Issue 2 2008Chris J. Hedegaard Summary Autoreactive T cells are thought to play an essential role in the pathogenesis of multiple sclerosis (MS). We examined the stimulatory effect of human myelin basic protein (MBP) on mononuclear cell (MNC) cultures from 22 patients with MS and 22 sex-matched and age-matched healthy individuals, and related the patient responses to disease activity, as indicated by magnetic resonance imaging. The MBP induced a dose-dependent release of interferon-, (IFN-,), tumour necrosis factor-, (TNF-,) and interleukin-10 (IL-10) by patient-derived MNCs. The patients' cells produced higher amounts of IFN-, and TNF-,, and lower amounts of IL-10, than cells from healthy controls (P < 0·03 to P < 0·04). Five patients with MS and no controls, displayed MBP-induced CD4+ T-cell proliferation. These high-responders exhibited enhanced production of IL-17, IFN-,, IL-5 and IL-4 upon challenge with MBP, as compared with the remaining patients and the healthy controls (P < 0·002 to P < 0·01). A strong correlation was found between the MBP-induced CD4+ T-cell proliferation and production of IL-17, IFN-,, IL-5 and IL-4 (P < 0·0001 to P < 0·01) within the patient group, and the production of IL-17 and IL-5 correlated with the number of active plaques on magnetic resonance images (P = 0·04 and P = 0·007). These data suggest that autoantigen-driven CD4+ T-cell proliferation and release of IL-17 and IL-5 may be associated with disease activity. Larger studies are needed to confirm this. [source] The Diffusion of Calculative and Collaborative HRM Practices in European FirmsINDUSTRIAL RELATIONS, Issue 4 2006ERIK POUTSMA The aim of this paper is to trace and explain variations in calculative and collaborative human resource management (HRM) practices between companies and across national borders. Variations and similarities are explained in terms of the convergence and divergence of HRM practices determined by national institutions, and the increasing influence of multinational companies (MNCs). We explore the diffusion of HRM practices in Europe over time, using data sets from two surveys conducted in several European countries in 1995 and 2000. We use institutional explanations for the development of three selected bundles of HRM practices: individual, calculative performance-oriented practices; collective incentive schemes for the alignment of interests; and collaborative practices that seek to enhance the commitment of employees. We found substantial effects of country-specific institutions and of the country of origin of MNCs, which clearly support the institutional duality thesis. Foreign-owned MNCs, especially those that are US-based, appear to moderate country-specific institutional effects on the diffusion of the three HRM bundles. [source] Unraveling Home and Host Country Effects: An Investigation of the HR Policies of an American Multinational in Four European CountriesINDUSTRIAL RELATIONS, Issue 2 2005PHIL ALMOND This article argues that the institutional "home" and "host" country effects on employment policy and practice in multinational corporations (MNCs) need to be analyzed within a framework which takes more account both of the multiple levels of embeddedness experienced by the MNC, and processes of negotiation at different levels within the firm. Using in-depth case study analysis of the human resource (HR) structure and industrial relations and pay policies of a large U.S.-owned MNC in the IT sector, across Germany, Ireland, Spain, and the United Kingdom, the article attempts to move towards such a framework. [source] The German model of employee relations on trial: negotiated and unilaterally imposed change in multi-national companiesINDUSTRIAL RELATIONS JOURNAL, Issue 1 2006Karen Williams ABSTRACT This article investigates the effects of negotiated and unilaterally imposed change on employee relations in the German subsidiaries of a Finnish and a German multi-national company (MNC). We look at how the strategies affect the sustainability of the current German model of employee relations and highlight some of the disadvantages of this model for global MNCs. [source] Evaluating Corporate Training and Development: An Indian ExperienceINTERNATIONAL JOURNAL OF TRAINING AND DEVELOPMENT, Issue 4 2001P. S. Yadapadithaya The central purpose of this article is to report on the current practices of evaluating training and development programs in the Indian corporate sector. The data were collected from written questionnaires mailed to 252 respondent companies,127 private, 99 public, and 26 multinational corporations (MNCs). The results and discussions are based on the major drivers and key result areas of training and development; purposes, levels, instruments, timing, and designs of evaluation; serious limitations of the training system; and finally the major challenges currently faced by the Indian corporate sector in strengthening the training and development function. [source] Soft Power and State,Firm Diplomacy: Congress and IT Corporate Activity in ChinaINTERNATIONAL STUDIES PERSPECTIVES, Issue 3 2009Jade Miller In today's globalized political economy, diplomacy between nation-states (state,state diplomacy) now exists alongside state,firm diplomacy, the negotiations between multinational corporations (MNCs) and the countries in which they do business. While the state must be committed to the interests of its MNCs in the interest of domestic state,firm diplomacy (maintaining a supportive business environment), it still has recourse to address failures in corporate diplomacy and to maintain the appearance of dominance on the world stage. This paper examined these strategies through a critical analysis of prepared testimony at the February 2006 congressional hearing regarding the controversial actions of four U.S. IT MNCs (Google, Microsoft, Yahoo, and Cisco) operating in China. I conclude that when the government is constrained from using its hard power on its MNCs, soft power becomes its most effective tool. Image, suggestion, and appearance,soft power,can be considered more important than legislation itself,hard power,and perhaps even the currency of current state,firm relations. [source] Does Foreign Direct Investment Replace Home Country Investment?JCMS: JOURNAL OF COMMON MARKET STUDIES, Issue 2 2000The Effect of European Integration on the Location of Swedish Investment The purpose of this article is to examine the effects of European integration on the location of investments by Swedish multinational corporations (MNCs). Evidence is presented about the extent to which European integration has attracted investment by Swedish MNCs, and whether foreign direct investment (FDI) is being undertaken at the expense of home country investment. In the empirical analysis, involving both OLS and iterative SUR techniques, a significant difference across industries has been confirmed. A substitutionary relationship between foreign and home country investment is found for more R&D-intensive production, whereas the opposite pattern seems to prevail for production based on traditional comparative advantage. The results of this study emphasize the importance of using disaggregated industry-level data when analysing the effects of foreign direct investment on home country investment. [source] Large-volume leukapheresis using femoral venous access for harvesting peripheral blood stem cells with the Fenwal CS 3000 Plus from normal healthy donors: Predictors of CD34+ cell yield and collection efficiencyJOURNAL OF CLINICAL APHERESIS, Issue 1 2003Sang Kyun Sohn Abstract The current paper reports on the predicting factors associated with satisfactory peripheral blood stem cell collection and the efficacy of large-volume leukapheresis (LVL) using femoral vein catheterization to harvest PBSCs with Fenwal CS 3000 Plus from normal healthy donors for allogeneic transplantation. A total of 113 apheresis procedures in 57 patients were performed. The median number of MNCs, CD3+ cells, and CD34+ cells harvested per apheresis was 5.3 × 108/kg (range, 0.3,11.0 × 108/kg), 3.0 × 108/kg (range, 0.2,6.6 × 108/kg), and 7.9 × 106/kg (range, 0.1,188.9 × 106/kg), respectively. The median collection efficiency of MNCs and CD34+ cells was 49.8% and 49.7%, respectively. A highly significant correlation was found between the collected CD34+ cell counts and the pre-apheresis WBC counts in the donors (P = 0.013), and between the collected CD34+ cell counts and the pre-apheresis peripheral blood (PB) CD34+ cell counts (P<0.001). Harvesting at least >4 × 106/kg CD34+ cells from the 1st LVL was achieved in 44 (77.2%) out of 57 donors and in 19 (90.5%) out of 21 donors with a PB-CD34+ cell count of >40/,l. There was no significant difference in the harvested MNC and CD34+ cell counts between the 1st and 2nd apheresis. The catheter-related complications included catheter obstruction (n = 2) and hematoma at the insertion site (n = 3). Accordingly, LVL using femoral venous access for allogeneic PBSC collection from normal healthy donors would appear to be safe and effective. J. Clin. Apheresis 18:10,15, 2003. © 2003 Wiley-Liss, Inc. [source] Formation of osteoclast-like cells from peripheral blood of periodontitis patients occurs without supplementation of macrophage colony-stimulating factorJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 7 2008Stanley T. S. Tjoa Abstract Aim: To determine whether peripheral blood mononuclear cells (PBMCs) from chronic periodontitis patients differ from PBMCs from matched control patients in their capacity to form osteoclast-like cells. Material and Methods: PBMCs from 10 subjects with severe chronic periodontitis and their matched controls were cultured on plastic or on bone slices without or with macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor- ,B ligand (RANKL). The number of tartrate-resistant acid phosphatase-positive (TRACP+) multinucleated cells (MNCs) and bone resorption were assessed. Results: TRACP+ MNCs were formed under all culture conditions, in patient and control cultures. In periodontitis patients, the formation of TRACP+ MNC was similar for all three culture conditions; thus supplementation of the cytokines was not needed to induce MNC formation. In control cultures, however, M-CSF or M-CSF/RANKL resulted in higher numbers compared with cultures without cytokines. Upregulations of osteoclast marker mRNA cathepsin K and carbonic anhydrase II confirmed the osteoclastic character. Bone resorption was only observed when PBMCs were cultured in the presence of M-CSF and RANKL. Conclusion: Our data indicate that PBMCs from periodontitis patients do not need priming by M-CSF to become osteoclast-like cells, suggesting that PBMCs from periodontitis patients are present in the circulation in a different state of activity. [source] China's WTO accession, state enterprise reform, and spatial economic restructuringJOURNAL OF INTERNATIONAL DEVELOPMENT, Issue 4 2002Simon Xiaobin Zhao China's accession to the World Trade Organization (WTO) promises to have profound effects on the development of the nation's economy and on nationwide enterprise reorganization. This paper attempts to address the relationship between China's WTO accession and state enterprise reforms, and their impacts on the performance of China's spatial economy, including the possible rise and fall of several large national financial centres, such as Hong Kong, Beijing, Shanghai, Guangzhou and Shenzhen. It is argued that China's new international ties will enhance current enterprise reforms and promote changes in the existing pattern of enterprise organization, with enterprise mergers, acquisitions, takeover activity and the formation of large multinational corporations (MNCs) becoming dominant trends within China's industrial development. Alongside these changes, some economic sectors, such as information technology (IT) and advanced professional services are predicted to become concentrated in several national information ,heartlands,' each having its own well-developed information infrastructure and other comparative advantages over traditional industrial centers. Meanwhile traditional industrial enterprises, while continuing to rely upon their pre-assigned resource priorities, will certainly face fierce international competition in the turbulent global market. The spatial shift of production and trade undoubtedly requires that Chinese enterprises, especially those that are state-owned, reorganize their production-trade systems according to the global ,rules of the game'. All of these changes, due to take effect imminently with China's WTO accession, will fundamentally restructure China's spatial economic landscape, including the creation of a new information heartland and hinterland that will in turn determine the life or death of the country's national financial centres. Copyright © 2002 John Wiley & Sons, Ltd. [source] Multi-national corporations and agricultural development: a study of contract farming in the Indian PunjabJOURNAL OF INTERNATIONAL DEVELOPMENT, Issue 2 2002Sukhpal Singh This paper examines the rationale, practice and implications of contract farming under the MNCs in vegetable crops in the Indian Punjab from the new institutional economics perspective. It is found that the MNCs deal with relatively large producers, their contracts are biased against the farmer, and the contract crops perpetuate many of the existing problems of the farming sector like high chemical input intensity, unstable future incomes, and social differentiation, though contracting has led to higher farm incomes and labour employment, especially for women. There is an inherent contradiction in the objectives of the contracting parties and that of the local economy and suitable institutions and organisations are not present in the state. Copyright © 2002 John Wiley & Sons, Ltd. [source] Wealth Effects of International Investments and Agency Problems for Korean Multinational FirmsJOURNAL OF INTERNATIONAL FINANCIAL MANAGEMENT & ACCOUNTING, Issue 3 2003Wi Saeng Kim This paper recognizes the recent surge in cross-border investments by MNCs from newly industrialized countries and investigates the wealth effects of FDI announcements by Korean firms, which are the leading FDI providers in Asia. The empirical results indicate that for Korean MNCs: 1) cross-border investments increase shareholder wealth; and 2) they do not obtain the firm-specific technological advantages over international competitors. The paper also presents evidence that cross-border investments do not increase shareholder wealth for the 30 largest chaebol -affiliates, and that shareholder wealth losses are greater when corporate ownership is concentrated, as suggested by Shleifer and Vishny (1997) and La Porta et al. (1998, 2000). [source] Metabotropic Glutamate Receptors: Gatekeepers of HomeostasisJOURNAL OF NEUROENDOCRINOLOGY, Issue 7 2010J. B. Kuzmiski The capacity to appropriately respond to physiological challenges or perturbations in homeostasis is a requisite for survival. It is becoming increasingly clear that long-lasting alterations in synaptic efficacy are a fundamental mechanism for modifying neuroendocrine and autonomic output. We review recent advances in our understanding of plasticity at glutamate synapses onto magnocellular neurones (MNCs) in the paraventricular and supraoptic nuclei of the hypothalamus, with a focus on the contributions of metabotropic glutamate receptors (mGluRs) to long-lasting modifications in synaptic efficacy. Special attention is paid to the role of presynaptic mGluRs as gatekeepers for metaplasticity and regulation of body fluid homeostasis. The work highlighted here provides insight into the synaptic mechanisms that couple MNC activity to physiological states. [source] Electrophysiological Identification of the Functional Presynaptic Nerve Terminals on an Isolated Single Vasopressin Neurone of the Rat Supraoptic NucleusJOURNAL OF NEUROENDOCRINOLOGY, Issue 5 2010T. Ohbuchi Release of arginine vasopressin (AVP) and oxytocin from magnocellular neurosecretory cells (MNCs) of the supraoptic nucleus (SON) is under the control of glutamate-dependent excitation and GABA-dependent inhibition. The possible role of the synaptic terminals attached to SON neurones has been investigated using whole-cell patch-clamp recording in in vitro rat brain slice preparations. Recent evidence has provided new insights into the repercussions of glial environment modifications on the physiology of MNCs at the synaptic level in the SON. In the present study, excitatory glutamatergic and inhibitory GABAergic synaptic inputs were recorded from an isolated single SON neurone cultured for 12 h, using the whole-cell patch clamp technique. Neurones expressed an AVP-enhanced green fluorescent protein (eGFP) fusion gene in MNCs. In addition, native synaptic terminals attached to a dissociated AVP-eGFP neurone were visualised with synaptic vesicle markers. These results suggest that the function of presynaptic nerve terminals may be evaluated directly in a single AVP-eGFP neurone. These preparations would be helpful in future studies aiming to electrophysiologically distinguish between the functions of synaptic terminals and glial modifications in the SON neurones. [source] Glial Limitans Elasticity Subjacent to the Supraoptic NucleusJOURNAL OF NEUROENDOCRINOLOGY, Issue 8 2004A. K. Salm Abstract Two previous studies from our laboratory have indicated that the ventral glial limitans subjacent to the hypothalamic supraoptic nucleus (SON-VGL) undergoes a reversible thinning upon chronic activation of the magnocellular neuroendocrine cells (MNCs) of the supraoptic nucleus (SON). Numerous other studies have shown that MNC somata hypertrophy with activation. One aim of the current study was to understand better how SON-VGL thinning occurs. A second aim was to quantify overall changes of the MNC somata region due to cellular hypertrophy to compare relative changes in dimensions. Here, we undertook a light microscopic stereological investigation of the SON and the subjacent SON-VGL of Nissl stained material under basal and activated conditions. Astrocyte numbers in the underlying SON-VGL remained stable across hydration state as did the overall volume of the SON-VGL and dendritic zone reference area. How these data are consistent with our earlier observations of SON-VGL thinning was resolved by the finding of a highly significant, 30% increase in the mediolateral dimension of the SON-VGL in dehydrated rats. These observations fit well with previous work from our laboratory that demonstrates a reorientation of SON-VGL astrocytes, from vertical to horizontal, which occurs in the activated SON-VGL. We found a significant, approximately 54%, increase in the overall volume of the MNC region of the SON. No significant rostrocaudal lengthening of the SON was detected, although a trend was evident. All the observed changes reversed with rehydration. These data indicate that elasticity of the SON-VGL acts to accommodate the volume expansion of the MNCs and enables the SON-VGL to continue as an interface between the underlying cerebrospinal fluid in the subarachnoid space and the expanded SON above. [source] The public affairs of internationalisation: balancing pressures from multiple environmentsJOURNAL OF PUBLIC AFFAIRS, Issue 1 2004Rian Drogendijk Abstract Managing public affairs is a very complex task for internationalising firms. Multinational companies (MNCs) are not only single organisations operating in a global environment, but at the same time they are collections of interlinked subsidiaries that operate in a diversity of national environments. This paper investigates conceptually how subsidiaries of MNCs build relationships with internal MNC counterparts and external market and non-market actors as they mature and build resources and capabilities. It shows that, in order to understand the dynamics of public affairs management in MNCs, we need to study the relationships of MNCs and their subsidiaries with a variety of stakeholders in the internal and external environment of the organisation. Copyright © 2004 Henry Stewart Publications [source] Culture and knowledge co-creation in R&D collaboration between MNCs and Chinese universitiesKNOWLEDGE AND PROCESS MANAGEMENT: THE JOURNAL OF CORPORATE TRANSFORMATION, Issue 2 2010Jianzhong Hong This paper examines the role of culture in university,industry R&D collaboration and knowledge interaction in the context of multinational corporations in China. Earlier university,industry studies focus primarily on one-way technology and knowledge transfer; however, the present study argues that in the studied context more interactive types of knowledge interaction like knowledge co-creation should be of key concern. The main challenge of the R&D collaboration lies in the understanding of culture in general and Chinese guanxi (interpersonal relationship) in particular in collaborative knowledge creation, in which the dominant type of knowledge involved is most often tacit, future oriented, complex and context-specific. This is particularly important when dealing simultaneously with multi-disciplinary applied research where cultural challenges appear prominent. Copyright © 2010 John Wiley & Sons, Ltd. [source] Knowledge creation and transfer in a cross-cultural context,empirical evidence from Tyco Flow ControlKNOWLEDGE AND PROCESS MANAGEMENT: THE JOURNAL OF CORPORATE TRANSFORMATION, Issue 3 2007Florian Kohlbacher The capability of multinational corporations (MNCs) to create and efficiently combine knowledge from different locations around the world is becoming increasingly important as a determinant of competitive advantage and will be more and more critical to their success and survival. Consequently, cultural differences and cross-cultural contexts play an essential role for and significantly influence global knowledge creation and management. This paper presents a case study resulting from a current empirical research project on knowledge management and the transfer of knowledge within organizations of MNCs. We describe and analyze the efforts of global market leader Tyco Flow Control (TFC)'s Japanese subsidiary KTM to transfer relevant,and often highly tacit,knowledge to a newly acquired production site in Taiwan. Challenges and difficulties encountered in the process of global knowledge management,in this case the transfer of knowledge from Japan to Taiwan,as well as the creation of new knowledge locally and its feedback,are illustrated and carefully examined. Finally, we discuss our findings and highlight practical implications for managers and international corporations in a global business environment. Copyright © 2007 John Wiley & Sons, Ltd. [source] The national innovation system and foreign R&D: the case of TaiwanR & D MANAGEMENT, Issue 5 2007Shin-Horng Chen R&D internationalization has increasingly involved countries outside the developed world. In addition, there has been a growing trend for countries in East Asia to seek to attract the R&D facilities of multinationals (MNCs). For such countries, they are faced with a fundamental question as to what kinds of impact MNCs' offshore R&D facilities will have on their own countries, especially in terms of technological innovation and industrial development. Set against the above backdrop, this paper sets out to examine a relatively new aspect of R&D internationalization related to global innovation networks and to open up the blackbox of the spillover effect regarding foreign R&D by examining the interplay of foreign R&D and Taiwan's national innovation system. The empirical part of the paper draws mainly upon intensive case studies of four high-profile foreign R&D facilities in the IT industry. The way foreign R&D interplays with Taiwan's NIS is examined in terms of the market & technology linkages. [source] | ||||||||||||||||||||||||||||||||||