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Longitudinal Associations (longitudinal + association)
Selected AbstractsCROSS-SECTIONAL AND LONGITUDINAL ASSOCIATIONS BETWEEN ANEMIA AND DEPRESSIVE SYMPTOMS IN THE ENGLISH LONGITUDINAL STUDY OF AGEINGJOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 5 2009Mark Hamer PhD No abstract is available for this article. [source] Longitudinal Associations Between Personality Profile Stability and Adjustment in College Students: Distinguishing Among Overall Stability, Distinctive Stability, and Within-Time NormativenessJOURNAL OF PERSONALITY, Issue 4 2010Theo A. Klimstra ABSTRACT In the present study, longitudinal associations of 3 aspects of personality profile stability (i.e., overall stability, distinctive stability, and within-time normativeness) with 3 adjustment measures (i.e., depressive symptoms, self-esteem, and delinquency) were examined, using 4 waves of longitudinal data on a Belgian college sample (N=565). Longitudinal path models revealed strong longitudinal associations between adjustment and overall stability. Subsequent analyses showed that it is not the degree to which one's personality profile consistently diverges from the average personality profile within a population (i.e., distinctive stability) that is related to adjustment but the degree to which a personality profile of an individual matches the average personality profile within the sample at a certain point in time (i.e., within-time normativeness). The current study thereby underscores the importance of distinguishing normativeness and distinctiveness when examining personality profile stability. [source] Longitudinal Associations Between Alcohol Problems and Depressive Symptoms: Early Adolescence Through Early AdulthoodALCOHOLISM, Issue 1 2009Naomi R. Marmorstein Background:, Alcohol use-related problems and depressive symptoms are clearly associated with each other, but results regarding the nature of this association have been inconsistent. In addition, the possible moderating effects of age and gender have not been comprehensively examined. The goals of this study were to clarify: (i) how depressive symptoms affect the levels and trajectory of alcohol use-related problems, (ii) how alcohol use-related problems affect the levels and trajectory of depressive symptoms, and (iii) whether there are differences in these associations at different points in development or between males and females. Methods:, Participants for this study were drawn from the National Longitudinal Study of Adolescent Health (AddHealth) data set, a community-based sample of 20,728 adolescents followed from adolescence through early adulthood. Multilevel models were used to assess how each problem affected the level and rate of change in the other problem over time; gender was considered as a possible moderator of these associations. Results:, The results indicated that alcohol use-related problems and depressive symptoms had reciprocal, positive associations with each other during the period from early adolescence through early adulthood; however, these effects differed somewhat by gender and age. High levels of depressive symptoms were associated with higher initial levels of alcohol problems (particularly among females), as well as faster increases in alcohol problems over time among males. High levels of alcohol problems were associated with higher initial levels of depressive symptoms (particularly among females), as well as less curvature in the slope of depressive symptoms so that although there was a large difference between people with high and low depressive symptoms in early adolescence, by early adulthood the difference was smaller (particularly among females). Conclusions:, These results highlight the importance of examining gender and age in studies on the associations between affective disorders and substance use disorders. [source] Personality pathology and substance abuse in eating disorders: A longitudinal studyINTERNATIONAL JOURNAL OF EATING DISORDERS, Issue 3 2008Heather Thompson-Brenner PhD Abstract Objective: Substance abuse has been shown to predict poor outcome in eating disorder (ED) samples, and prior cross-sectional data on personality subtypes of EDs suggest that substance abuse is associated with dysregulated and possibly avoidant-insecure subtypes. This study investigates longitudinal associations between personality and substance use. Method: Personality pathology and substance use were assessed in 213 individuals with anorexia nervosa and bulimia nervosa at baseline; substance use was assessed at regular follow-up intervals over a 9-year period. Results: Of the five personality factors identified, the obsessional-sensitive and high-functioning types were negatively associated with substance abuse at baseline, while the behaviorally dysregulated type was positively associated with substance abuse at baseline. Longitudinal associations were observed, suggesting that obsessional-sensitive personality type was protective against the development of substance abuse. Longitudinal associations between the other personality types and substance abuse were nonsignificant after baseline substance abuse history was included as a covariate in the model. Conclusion: Substance use demonstrates cross-sectional associations with personality style, but substance abuse history appears to be the most important predictor of future substance abuse in women with eating disorders. © 2007 by Wiley Periodicals, Inc. Int J Eat Disord 2008 [source] Depressive Symptoms and Cognitive Decline in Community-Dwelling Older AdultsJOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 5 2010Sebastian Köhler PhD OBJECTIVES: To examine the temporal association between depressive symptoms and cognitive functioning and estimate the effect measure modification of the apolipoprotein E (APOE) ,4 allele on this relationship. DESIGN: Prospective cohort study. SETTING: General community. PARTICIPANTS: Population-based sample of 598 cognitively intact older adults aged 60 and older, with re-assessments after 3 (N=479) and 6 years (N=412). MEASUREMENTS: Depressive symptoms (Symptom Checklist) and neurocognitive functioning (memory, Visual Verbal Learning Test; attention, Stroop Color,Word Test; processing speed, Letter Digit Substitution Test; general cognition, Mini-Mental State Examination). Longitudinal associations were assessed using linear mixed models. The risk for cognitive impairment, no dementia (CIND) was examined using logistic regression. RESULTS: Adjusting for age, sex, education, and baseline cognition, the rate of change in memory z -scores was 0.00, ,0.11, ,0.20, and ,0.37 for those in the lowest (reference group), second, third, and highest depressive symptom quartiles at baseline, respectively (P<.001 for highest vs lowest quartile). The odds ratios for developing CIND with amnestic features were 1.00, 0.87, 0.69, and 2.98 for the four severity groups (P=.05 for highest vs lowest quartile). Associations were strongest for those with persistent depressive symptoms, defined as high depressive symptoms at baseline and at least one follow-up visit. Results were similar for processing speed and global cognitive function but were not as strong for attention. No APOE interaction was observed. CONCLUSION: Depression and APOE act independently to increase the risk for cognitive decline and may provide targets for prevention and early treatment. [source] Is Being Popular a Risky Proposition?JOURNAL OF RESEARCH ON ADOLESCENCE, Issue 1 2008Lara Mayeux Longitudinal associations between social preference, perceived popularity, and risk behaviors (smoking, alcohol use, and sexual activity) were examined in a sample of high school students. Social preference did not predict any of the risk behaviors assessed, although the interaction between gender and social preference was predictive of sexual behavior. Perceived popularity in Grade 10 was predictive of increased alcohol use and sexual activity in Grade 12 for both boys and girls. A reciprocal relationship was found for boys, in which smoking in Grade 10 also predicted gains in perceived popularity over time. Furthermore, results suggested that gains in perceived popularity may be associated with subsequent losses in social preference over time, lending support for the "cycle of popularity" observed by Eder. Implications are discussed, including the personal impact of risk behaviors on perceived popular teens, as well as the broader influence their behavior may have on their less popular counterparts. [source] A longitudinal study of cannabis use and mental health from adolescence to early adulthoodADDICTION, Issue 4 2000Rob McGee Aims. To examine the longitudinal association between cannabis use and mental health. Design. Information concerning cannabis use and mental health from 15 to 21 years was available for a large sample of individuals as part of a longitudinal study from childhood to adulthood. Participants. Participants were enrolled in the Dunedin Multidisciplinary Health and Development Study, a research programme on the health, development and behaviour of a large group of New Zealanders born between 1 April 1972 and 31 March 1973. Measurements. Cannabis use and identification of mental disorder was based upon self-report as part of a general assessment of mental health using a standard diagnostic interview. Daily smoking and alcohol use at age 15 were assessed by self-report. Indices of family socio-economic status, family climate and parent - child interaction were formed using information gathered from parent report and behavioural observations over early childhood. Childhood behaviour problems were assessed by parent and teacher report. Attachment to parents was assessed in adolescence. Findings. Cross-sectional associations between cannabis use and mental disorder were significant at all three ages. Both outcome variables shared similar pathways of low socio-economic status and history of behaviour problems in childhood, and low parental attachment in adolescence. Mental disorder at age 15 led to a small but significantly elevated risk of cannabis use at age 18; by contrast, cannabis use at age 18 elevated the risk of mental disorder at age 21. The latter association reflected the extent to which cannabis dependence and other externalizing disorders at age 21 were predicted by earlier level of involvement with cannabis. Conclusions. The findings suggest that the primary causal direction leads from mental disorder to cannabis use among adolescents and the reverse in early adulthood. Both alcohol use and cigarette smoking had independent associations with later mental health disorder. [source] Influence of social network characteristics on cognition and functional status with agingINTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY, Issue 9 2008Ariel Frank Green Abstract Objective To determine whether more frequent engagement in larger social networks, and more emotional support protect against cognitive and functional decline with aging. Methods We examined the influence of social networks on cognition and instrumental activities of daily living (IADLs) over a median interval of 10.9 years. Data were from the Baltimore follow-up of the Epidemiologic Catchment Area (ECA) study, a community-based sample of adults in eastern Baltimore. Eight hundred and seventy-four participants completed cognitive testing at both the third and fourth study waves (1993,1996 and 2003,2004) on the Mini-Mental State Examination (MMSE) and a delayed word recall task. Functional status at both waves was self-reported on the Lawton-Brody IADL scale. Social network characteristics, assessed at the third study wave, included network size, frequency of contact, and emotional support. Results In cross-sectional analyses at wave 3, larger networks were associated with higher MMSE and better delayed recall scores. This association persisted after adjustment for covariates. More emotional support was associated with better functional status, before and after adjustment. By contrast, social networks were not longitudinally associated with cognitive change, with two counter-intuitive exceptions: more frequent contact and more emotional support were associated with worse delayed recall and IADL scores after adjustment. Conclusions There was no evidence of a longitudinal association between social networks and cognition or IADLs, although a clear cross-sectional association exists. Together, these findings suggest the emergence of social isolation in individuals declining in cognition and functioning, rather than a protective effect of social networks. Copyright © 2008 John Wiley & Sons, Ltd. [source] Cognitive Status, Muscle Strength, and Subsequent Disability in Older Mexican AmericansJOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 9 2005Mukaila A. Raji MD Objectives: To examine the association between Mini-Mental State Examination (MMSE) score and subsequent muscle strength (measured using handgrip strength) and to test the hypothesis that muscle strength will mediate any association between impaired cognition and incident activity of daily living (ADL) disability over a 7-year period in elderly Mexican Americans who were initially not disabled. Design: A 7-year prospective cohort study (1993,2001). Setting: Five southwestern states (Texas, New Mexico, Colorado, Arizona, and California). Participants: Two thousand three hundred eighty-one noninstitutionalized Mexican-American men and women aged 65 and older with no ADL disability at baseline. Measurements: In-home interviews in 1993/1994, 1995/1996, 1998/1999, and 2000/2001 assessed social and demographic factors, medical conditions (diabetes mellitus, stroke, heart attack, and arthritis), body mass index (BMI), depressive symptomatology, handgrip muscle strength, and ADLs. MMSE score was dichotomized as less than 21 for poor cognition and 21 or greater for good cognition. Main outcomes measures were mean and slope of handgrip muscle strength over the 7-year period and incident disability, defined as new onset of any ADL limitation at the 2-, 5-, or 7-year follow-up interview periods. Results: In mixed model analyses, there was a significant cross-sectional association between having poor cognition (MMSE<21) and lower handgrip strength, independent of age, sex, and time of interview (estimate=,1.41, standard error (SE)=0.18; P<.001). With the introduction of a cognition-by-time interaction term into the model, there was also a longitudinal association between poor cognition and change in handgrip strength over time (estimate=,0.25, SE=0.06; P<.001), indicating that subjects with poor cognition had a significantly greater decline in handgrip strength over 7 years than those with good cognition, independent of age, sex, and time. This longitudinal association between poor cognition and greater muscle decline remained significant (P<.001) after controlling for age, sex, education, and time-dependent variables of depression, BMI, and medical conditions. In general estimation equation models, having poor cognition was associated with greater risk of 7-year incident ADL disability (odds ratio=2.01, 95% confidence interval (CI)=1.60,2.52); the magnitude of the association decreased to 1.66 (95% CI=1.31,2.10) when adjustment was made for handgrip strength. Conclusion: Older Mexican Americans with poor cognition had steeper decline in handgrip muscle strength over 7 years than those with good cognition, independent of other demographic and health factors. A possible mediating effect of muscle strength on the association between poor cognition and subsequent ADL disability was also indicated. [source] Work-related stress, inability to relax after work and risk of adult asthma: a population-based cohort studyALLERGY, Issue 10 2010A. Loerbroks To cite this article: Loerbroks A, Gadinger MC, Bosch JA, Stürmer T, Amelang M. Work-related stress, inability to relax after work and risk of adult asthma: a population-based cohort study. Allergy 2010; 65: 1298,1305. Abstract Background:, There is an extensive literature linking stressful work conditions to adverse health outcomes. Notwithstanding, the relationship with asthma has not been examined, although various other measures of psychological stress have been associated with asthma. Therefore, we aimed to investigate the relation between work stress and asthma prevalence and incidence. Methods:, We used data from a population-based cohort study (n = 5114 at baseline in 1992,1995 and n = 4010 at follow-up in 2002/2003). Asthma was measured by self-reports. Two scales that assessed psychologically adverse work conditions were extracted from a list of work-condition items by factor analysis (these scales were termed ,work stress' and ,inability to relax after work'). For each scale, the derived score was employed both as continuous z -score and as categorized variable in analyses. Associations with asthma were estimated by prevalence ratios (PRs) and risk ratios (RRs) using Poisson regression with a log-link function adjusting for demographics, health-related lifestyles, body mass index and family history of asthma. Analyses were restricted to those in employment (n = 3341). Results:, Work stress and inability to relax z -scores were positively associated with asthma prevalence (PR = 1.15, 95%CI = 0.97, 1.36 and PR = 1.43, 95%CI = 1.12, 1.83, respectively). Prospective analyses using z -scores showed that for each 1 standard deviation increase in work stress and inability to relax, the risk of asthma increased by approximately 40% (RR for work stress = 1.46, 95%CI = 1.06, 2.00; RR for inability to relax = 1.39, 95%CI = 1.01, 1.91). Similar patterns of associations were observed in analyses of categorized exposures. Conclusions:, This is the first study to show a cross-sectional and longitudinal association of work stress with asthma. [source] White matter lesions volume and motor performances in the elderly,ANNALS OF NEUROLOGY, Issue 6 2009Aïcha Soumaré MSc Objectives To investigate the cross-sectional and longitudinal associations between performance-based measures of motor function and volume of white matter lesions (WMLs), and to examine the influence of the localization of these lesions. Methods At baseline, motor performances (maximum walking speed, Tinetti gait and balance subscales) were assessed in 1,702 subjects aged 80 years or younger from the Dijon (France), France center of the Three-City study. Volumes of WMLs lesions (total, periventricular, deep) were measured using an automated method of tissue segmentation and quantification of lesion size. At 8-year follow-up, walking speed was evaluated in 1,086 subjects. Results At baseline, mean and 95% confidence interval (CI) walking speed was lower in subjects with total volumes of WMLs ,90th percentile (1.50 [1.45,1.55] m/s) than in subjects with lower volumes (1.56 [1.55,1.58] m/s; p = 0.004). Baseline total volumes of WMLs above the 90th percentile predicted walking speed decline during follow-up (odds ratio [95% CI] for having the greatest walking speed decline = 2.3 [1.3,4.1], p = 0.006). Moreover, high volumes of periventricular but not deep WMLs were associated with slower walking speed at baseline (p = 0.005) and over time (p = 0.001), and with lower Tinetti gait subscore (p = 0.02). Interpretation Our study shows a cross-sectional and longitudinal association between high total volumes of WMLs, in particular volumes above the 90th percentile, and impaired mobility. These associations were independent of several confounders, including cognition, and were mainly accounted for by volumes of periventricular WMLs. These findings support the hypothesis of a vascular contribution to motor decline in the elderly. Ann Neurol 2009;65:706,715 [source] Assessing the Effects of Maternal Symptoms and Homelessness on the Mental Health Problems in their ChildrenCHILD AND ADOLESCENT MENTAL HEALTH, Issue 4 2009Ilan Harpaz-Rotem Objective:, This study examines the longitudinal association between measures of child well being and maternal posttraumatic stress disorder symptoms, homelessness, substance abuse, and other psychiatric conditions. Method:, A sample of 142 mothers who were veterans of the US armed forces were assessed at program entry and every three months thereafter for one year. A repeated-measures with mixed-effects analytic strategy was used to assess the association of children's mental health, school enrolment and attendance with measures of maternal psychiatric symptoms and homelessness. Results:, Significant associations between mothers' psychiatric symptoms and child well-being were identified. However, the multivariable mixed-models suggest that increased depression and anxiety symptoms among children were associated primarily with mothers' PTSD, and not depression, symptoms. Conclusions:, These findings provide evidence of an association between maternal and child mental health and may suggest that treating maternal PTSD symptoms may also benefit children, regardless of whether the child was also exposed to the traumatic experience. [source] The Dynamics of Life Stressors and Depressive Symptoms in Early Adolescence: A Test of Six Theoretical ModelsCHILD DEVELOPMENT, Issue 4 2008Margaret Clements Structural equation modeling was used to compare 6 competing theoretically based psychosocial models of the longitudinal association between life stressors and depressive symptoms in a sample of early adolescents (N= 907; 40% Hispanic, 32% Black, and 19% White; mean age at Time 1 = 11.4 years). Only two models fit the data, both of which included paths modeling the effect of depressive symptoms on stressors recall: The mood-congruent cognitive bias model included only depressive symptoms to life stressors paths (DS,S), whereas the fully transactional model included paths representing both the DS,S and stressors to depressive symptoms (S,DS) effects. Social causation models and the stress generation model did not fit the data. Findings demonstrate the importance of accounting for mood-congruent cognitive bias in stressors,depressive symptoms investigations. [source] Subjective quality of life aspects predict depressive symptoms over time: results from a three-wave longitudinal studyACTA PSYCHIATRICA SCANDINAVICA, Issue 6 2009C. Kuehner Objective:, Little is known about predictive effects of quality of life aspects on the course of depressive symptoms in clinical and non-clinical settings. This study examines longitudinal associations between depressive symptoms and subjective quality of life (QOL) dimensions using a parallel sample of depressed patients and community controls. Method:, Eighty-two depressed patients were investigated 1, 6, and 42 months after hospital discharge together with 76 community controls regarding depressive symptoms measured by Montgomery Asberg Depression Rating Scale (MADRS) and QOL (WHOQOL-BREF). Data analysis included time-lagged linear models. Results:, Physical, psychological, environmental and overall QOL, controlled for depressive symptoms, predicted future depression levels. Group status did not moderate these associations. Depressive symptoms predicted future QOL levels only regarding social relations. Conclusion:, Our study suggests that subjective QOL domains have prognostic value for the course of depressive symptoms over time, both in patient and community samples. Respective self-perceptions should therefore be directly addressed by therapeutic and preventive interventions. [source] Substance use and common child mental health problems: examining longitudinal associations in a British sampleADDICTION, Issue 8 2010Anna Goodman ABSTRACT Aims To examine the longitudinal associations in both directions between mental health and substance use in adolescence. Design Three-year longitudinal cohort. Setting Britain (nationally representative sample). Participants 3607 youths aged 11,16 years at baseline. Measurements Externalizing and internalizing mental health problems were measured using brief questionnaires (parent-reported Strengths and Difficulties Questionnaire) and diagnostic interviews, including clinician-rated diagnoses of mental disorder. Substance use was measured by youth self-report, and included regular smoking, frequent alcohol consumption, regular cannabis use and ever taking other illicit drugs. Findings Externalizing (specifically behavioural) problems at baseline independently predicted all forms of substance use, with a particularly strong effect on smoking. In all cases this association showed a dose,response relationship. In contrast, although internalizing problems had a strong univariable association with smoking, this disappeared after adjusting for comorbid externalizing problems. There was little or no evidence that baseline substance use predicted mental health at follow-up. Conclusions Externalizing problems predict adolescent substance use, and adjusting for comorbid externalizing problems is vital when investigating the effects of internalizing problems. A dose,response effect of externalizing problems is seen across the full range. Programmes seeking to prevent adolescent substance use by reducing externalizing problems may therefore wish to consider population-wide interventions rather than targeting individuals only at the negative extreme. [source] Five-year longitudinal predictive factors for disordered eating in a population-based sample of overweight adolescents: Implications for prevention and treatmentINTERNATIONAL JOURNAL OF EATING DISORDERS, Issue 7 2009Dianne Neumark-Sztainer PhD Abstract Objective The objective of this study is to identify predictors of prevalence and incidence of disordered eating (binge eating and extreme weight control behaviors) among overweight adolescents. Method Five-year longitudinal associations were examined in 412 overweight adolescents who participated in Project EAT-I and II. Results Among both overweight males and females, risk factors for disordered eating included exposure to weight loss magazine articles, higher weight importance, and unhealthy weight control behaviors, while family connectedness, body satisfaction, and regular meals were protective factors, although there were some differences in predictors of prevalence (total cases) versus incidence (new cases) of disordered eating. Among males, poor eating patterns, including fast food and sweetened beverage intake, increased risk for disordered eating, and the use of healthy weight control behaviors was protective. Discussion Attention should be directed toward decreasing disordered eating among overweight adolescents. Findings suggest the importance of promoting positive family relationships, psychological health, and regular meals, and steering adolescents away from overemphasizing weight and using unhealthy weight control behaviors. © 2009 by Wiley Periodicals, Inc. Int J Eat Disord 2009 [source] Personality pathology and substance abuse in eating disorders: A longitudinal studyINTERNATIONAL JOURNAL OF EATING DISORDERS, Issue 3 2008Heather Thompson-Brenner PhD Abstract Objective: Substance abuse has been shown to predict poor outcome in eating disorder (ED) samples, and prior cross-sectional data on personality subtypes of EDs suggest that substance abuse is associated with dysregulated and possibly avoidant-insecure subtypes. This study investigates longitudinal associations between personality and substance use. Method: Personality pathology and substance use were assessed in 213 individuals with anorexia nervosa and bulimia nervosa at baseline; substance use was assessed at regular follow-up intervals over a 9-year period. Results: Of the five personality factors identified, the obsessional-sensitive and high-functioning types were negatively associated with substance abuse at baseline, while the behaviorally dysregulated type was positively associated with substance abuse at baseline. Longitudinal associations were observed, suggesting that obsessional-sensitive personality type was protective against the development of substance abuse. Longitudinal associations between the other personality types and substance abuse were nonsignificant after baseline substance abuse history was included as a covariate in the model. Conclusion: Substance use demonstrates cross-sectional associations with personality style, but substance abuse history appears to be the most important predictor of future substance abuse in women with eating disorders. © 2007 by Wiley Periodicals, Inc. Int J Eat Disord 2008 [source] Cardiovascular Disease Is Associated with Greater Incident Dehydroepiandrosterone Sulfate Decline in the Oldest Old: The Cardiovascular Health Study All Stars StudyJOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 3 2010Jason L. Sanders BA OBJECTIVES: To describe cross-sectional and longitudinal associations with dehydroepiandrosterone sulfate (DHEAS) and change in DHEAS with age. DESIGN: Longitudinal cohort study. SETTING: Pittsburgh, Pennsylvania. PARTICIPANTS: Cardiovascular Health Study All Stars study participants assessed in 2005/06 (N=989, mean age 85.2, 63.5% women, 16.5% African American). MEASUREMENTS: Health characteristics were assessed in 2005/06 according to DHEAS level, mean DHEAS and DHEAS change across age categories were tested, and linear and logistic regression was used to identify factors present in 1996/97 associated with continuous and categorical DHEAS change. RESULTS: Mean ± standard deviation DHEAS was 0.555 ± 0.414 ,g/mL in 1996/97 and 0.482 ± 0.449 ,g/mL in 2005/06 for women and 0.845 ± 0.520 ,g/mL in 1996/97 and 0.658 ± 0.516 ,g/mL in 2005/06 for men. In 2005/06, DHEAS was lower in women and subjects with cardiovascular disease (CVD) and chronic pulmonary disease and higher for African Americans and subjects with hypertension and high cholesterol. Mean DHEAS change was greater in men (,0.200 ,g/mL) than in women (,0.078 ,g/mL) (P<.001). Each 1-year increase in age attenuated the effect of male sex by 0.01 ,g/mL (P=.009), abolishing the sex difference in DHEAS change by age 79. Presence of CVD before the study period was associated with greater absolute DHEAS change (,=,0.04 ,g/mL, P=.04) and with the fourth quartile of DHEAS change versus the first to third quartiles (odds ratio=1.46, 95% confidence interval=1.03,2.05). CONCLUSION: DHEAS change continues into very old age, is not homogenous, is affected by sex, and is associated with prevalent CVD. Future studies should investigate factors that might accelerate DHEAS decline. [source] Longitudinal Associations Between Personality Profile Stability and Adjustment in College Students: Distinguishing Among Overall Stability, Distinctive Stability, and Within-Time NormativenessJOURNAL OF PERSONALITY, Issue 4 2010Theo A. Klimstra ABSTRACT In the present study, longitudinal associations of 3 aspects of personality profile stability (i.e., overall stability, distinctive stability, and within-time normativeness) with 3 adjustment measures (i.e., depressive symptoms, self-esteem, and delinquency) were examined, using 4 waves of longitudinal data on a Belgian college sample (N=565). Longitudinal path models revealed strong longitudinal associations between adjustment and overall stability. Subsequent analyses showed that it is not the degree to which one's personality profile consistently diverges from the average personality profile within a population (i.e., distinctive stability) that is related to adjustment but the degree to which a personality profile of an individual matches the average personality profile within the sample at a certain point in time (i.e., within-time normativeness). The current study thereby underscores the importance of distinguishing normativeness and distinctiveness when examining personality profile stability. [source] Risk Factors of Sexual Harassment by Peers: A Longitudinal Investigation of African American and European American AdolescentsJOURNAL OF RESEARCH ON ADOLESCENCE, Issue 2 2007Sara E. Goldstein The present research explores risk factors for, and longitudinal associations of, sexual harassment by peers during adolescence. Eight-hundred and seventy-two African American and European American adolescents (65.4% African American, 51.1% females) were assessed during the summer after the eighth grade (mean age=14.2 years) and then again in the 11th grade (mean age=17.1 years). At the first assessment, adolescents were asked about their experiences with sexual harassment, their psychological reactions to sexual harassment, and also about their peer relationships, perceived pubertal timing, problem behavior, and mental health. At the second assessment, adolescents reported on their problem behavior and mental health. In general, youth who associated with peers who were involved in problem behavior were at risk for victimization. Among females, those who perceived themselves to be experiencing early pubertal development were also at risk. Additionally, for some adolescents, sexual harassment predicted later adjustment difficulties. [source] Peer Crowd Affiliation and Internalizing Distress in Childhood and Adolescence: A Longitudinal Follow-Back StudyJOURNAL OF RESEARCH ON ADOLESCENCE, Issue 3 2002Mitchell J. Prinstein Concurrent and longitudinal associations between peer crowd affiliation and internalized distress were examined in a sample of 246 youth (148 girls, 98 boys). Children completed measures of depression, social anxiety, loneliness, and self-esteem when they were in grades 4 to 6 (Time 1), and again 6 years later during adolescence (grades 10 , 12; Time 2). At Time 2, adolescents also reported their self-concept and their identification with reputation-based peer crowds, including Populars, Jocks, Brains, Burnouts, Non-Conformists, and None/Average crowds. Results indicated that adolescents' report of peer crowd affiliation was concurrently associated with self-concept and levels of internalizing distress. Follow-back analyses of internalizing trajectories revealed that Populars/Jocks had experienced significant declines in internalizing distress across development, whereas Brains exhibited some increases in internalizing distress between childhood and adolescence. [source] White matter lesions volume and motor performances in the elderly,ANNALS OF NEUROLOGY, Issue 6 2009Aïcha Soumaré MSc Objectives To investigate the cross-sectional and longitudinal associations between performance-based measures of motor function and volume of white matter lesions (WMLs), and to examine the influence of the localization of these lesions. Methods At baseline, motor performances (maximum walking speed, Tinetti gait and balance subscales) were assessed in 1,702 subjects aged 80 years or younger from the Dijon (France), France center of the Three-City study. Volumes of WMLs lesions (total, periventricular, deep) were measured using an automated method of tissue segmentation and quantification of lesion size. At 8-year follow-up, walking speed was evaluated in 1,086 subjects. Results At baseline, mean and 95% confidence interval (CI) walking speed was lower in subjects with total volumes of WMLs ,90th percentile (1.50 [1.45,1.55] m/s) than in subjects with lower volumes (1.56 [1.55,1.58] m/s; p = 0.004). Baseline total volumes of WMLs above the 90th percentile predicted walking speed decline during follow-up (odds ratio [95% CI] for having the greatest walking speed decline = 2.3 [1.3,4.1], p = 0.006). Moreover, high volumes of periventricular but not deep WMLs were associated with slower walking speed at baseline (p = 0.005) and over time (p = 0.001), and with lower Tinetti gait subscore (p = 0.02). Interpretation Our study shows a cross-sectional and longitudinal association between high total volumes of WMLs, in particular volumes above the 90th percentile, and impaired mobility. These associations were independent of several confounders, including cognition, and were mainly accounted for by volumes of periventricular WMLs. These findings support the hypothesis of a vascular contribution to motor decline in the elderly. Ann Neurol 2009;65:706,715 [source] Psychosocial Work Characteristics as Predictors of Affective Organisational Commitment: A Longitudinal Multi-Level Analysis of Occupational Well-BeingAPPLIED PSYCHOLOGY: HEALTH AND WELL-BEING, Issue 2 2010Thomas Clausen The purpose of this study was to identify longitudinal associations between psychosocial work characteristics and affective organisational commitment among 6,299 employees in the Danish eldercare services. Individual-level measures and group-level measures of psychosocial work characteristics were included in multi-level analyses. At the workgroup level, quality of leadership, influence at work, emotional demands, and work pace predicted affective organisational commitment at follow-up. At the individual level, quality of leadership, influence at work, team climate, role ambiguity, and work pace predicted affective organisational commitment at follow-up. Finally, a multi-level model including both individual- and group-level measures showed that quality of leadership measured at the group level and influence at work and quality of leadership measured at the individual level contributed to predicting affective organisational commitment at follow-up, while adjusting for baseline levels of affective organisational commitment. The results thus imply that affective organisational commitment is conditioned by individual and contextual factors in the psychosocial work environment and that multi-level models add to our understanding of complex organisational phenomena. As affective organisational commitment can be considered an important constituent of occupational well-being, implications for interventions in the psychosocial work environment to increase affective organisational commitment are also discussed. [source] Lack of association between television viewing, soft drinks, physical activity and body mass index in childrenACTA PAEDIATRICA, Issue 6 2008Kelly Laurson Abstract Objective: To examine the cross-sectional and longitudinal associations of physical activity, screen time and dietary habits on the body mass index (BMI) of children. Methods: A cohort of 122 girls and 146 boys (age at entry 10 years) from three rural states in the western USA was studied over an 18-month period. Subjects were measured for height and weight. Habitual physical activity, screen time (television viewing, video games and computer use) and dietary variables were assessed by a questionnaire. Cross-sectional and longitudinal analyses were conducted to examine the associations between physical activity, screen time and diet with BMI at baseline and follow-up and change in BMI. Results: At baseline, approximately 10% of boys and girls were obese and 17.8% of boys and 14.8% of girls were overweight. BMI showed a high degree of stability for boys and girls (r = 0.90), whereas physical activity, screen time and dietary habits showed moderate stability (r = 0.31,0.50) across the 18-month period. Cross-sectional and longitudinal correlations between physical activity, screen time, diet and BMI were low and non-significant (r < 0.15). The regression models explained between 8% and 22% of the variance in the change in BMI; however, none of the predictor variables were statistically significant. Conclusion: Physical activity, screen time and dietary habits were not significantly related to the BMI in cross-sectional or longitudinal analyses. Further research is warranted to better understand the complex, multifactorial phenotype of the BMI in growing and maturing children. [source] Cortisol levels and measures of body composition in middle-aged and older menCLINICAL ENDOCRINOLOGY, Issue 1 2007Thomas G. Travison Summary Introduction, Similarities in the symptomatic expressions of excess adiposity and hypercortisolaemic conditions suggest that elevated glucocorticoid exposure may influence the pathogenesis of obesity. Circulating cortisol levels are not typically elevated in obese subjects, but data from large prospective samples are rare. We undertook an analysis to determine both cross-sectional and longitudinal associations between body composition and serum cortisol concentrations in a randomly chosen group of 999 community-dwelling men, aged 40,79 years. Methods, Data were obtained from the two follow-up waves of the Massachusetts Male Ageing Study (T2: 1995,97; T3: 2002,04). Partial correlation and multivariate regression analyses were used to estimate cross-sectional (T2) and longitudinal associations between serum cortisol concentrations and a range of measures of subjects' body composition, including weight, body mass index (BMI), waist circumference (WC), waist-to-hip girth ratio (WHR), and percentage body fat (measured by bioelectrical impedance at T3); similar analyses were conducted to assess the association between change (T2 to T3) in serum cortisol and simultaneous change in body composition parameters. Results, We observed weak negative associations between cortisol concentrations and all body composition parameters, with the exception of percentage body fat. Longitudinal results demonstrated similar relationships but associations were of lesser magnitude. T2 cortisol concentrations were not associated with change in body composition over time, whereas T2 body size was positively associated with longitudinal changes in cortisol concentrations, providing limited evidence that weight change drives changes in cortisol concentrations, rather than vice versa. Results were unchanged when age and other covariate effects were controlled. Conclusions, Circulating cortisol concentrations are somewhat lower in obese than in nonobese community-dwelling men. There is some evidence that excess adiposity presages increases in cortisol concentrations, rather than the reverse. However, this observation should be greeted with caution, as age-related weight loss , and not gain , was associated with simultaneous increases in serum cortisol concentrations. [source] | |||||||||||||