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Antimicrobial Activity (antimicrobial + activity)
Kinds of Antimicrobial Activity Selected AbstractsANTIOXIDANT AND ANTIMICROBIAL ACTIVITY OF DIFFERENT FLORAL ORIGIN HONEYS FROM TURKIYEJOURNAL OF FOOD BIOCHEMISTRY, Issue 2010ESRA ULUSOY ABSTRACT The bioactivities of phenolic extracts of nine Turkish honeys from different floral sources were investigated. The antioxidant properties of the extracts were assessed by ferric reducing/antioxidant power (FRAP) assay, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical-scavenging activity and cupric reducing antioxidant capacity (CUPRAC) assay. The total phenolic contents measured by Folin,Ciocalteau method varied from 66 to 223 mg/g extract as gallic acid equivalent. The antioxidant activities found with CUPRAC, expressed as trolox equivalent antioxidant capacity, ranged from 124.8 to 532 µmol/g, those determined with DPPH· expressed as IC50 ranged from 84 to 296 µg/mL, and those determined with FRAP expressed as trolox equivalent were in 33,166 µmol/g range. The antioxidant activities showed a marked correlation with total phenolics. In the antimicrobial tests using six bacteria and a yeast, Escherichia coli was moderately sensitive to each extract. There was no correlation between antimicrobial activity and total phenolic contents. PRACTICAL APPLICATIONS Honey has functional properties and promotes human health, and such properties depend largely on the floral source. Although studies on screening the antimicrobial and antioxidant activity of raw honey samples have been done densely, studies on phenolic compounds of honey are very limited. The present study demonstrates that honey phenolic compounds are partially responsible for honey antioxidant activity, displaying the relevance of honey as both healthy foodstuff and source of antioxidant. [source] ANTIMICROBIAL ACTIVITY OF MELANOIDINSJOURNAL OF FOOD QUALITY, Issue 2 2007JOSÉ A. RUFIÁN-HENARES ABSTRACT Melanoidins are high molecular weight compounds formed during the final stage of the Maillard reaction. Melanoidins have been studied in recent years because of their nutritional, biological and health implications, apart from their role on the stability during processing and shelf life of foods. A fast and robust microtiter plate-based assay for a quantitative screening of the antimicrobial activity of melanoidins was applied. Oxytetracyclin was used as reference for assessing the antimicrobial activity of different melanoidins isolated from model systems. The minimum inhibitory concentration was calculated, and activity was related to the antimicrobial activity of an oxytetracyclin solution (100 µg/L). Glucose,lysine melanoidin exerted the highest antimicrobial activity, being at a concentration of 1 mg/mL, equivalent to an oxytetracyclin solution of 170 µg/L. [source] Screening for Alternative Antibiotics: An Investigation into the Antimicrobial Activities of Medicinal Food Plants of MauritiusJOURNAL OF FOOD SCIENCE, Issue 3 2010M.F. Mahomoodally ABSTRACT:, The present study was designed to evaluate the antimicrobial activities of 2 endemic medicinal plants; Faujasiopsis flexuosa,(Asteraceae) (FF) and Pittosporum senacia,(Pittosporaceae) (PS) and 2 exotic medicinal plants, Momordica charantia,(Cucurbitaceae) (MC) and Ocimum tenuiflorum,(Lamiaceae) (OT) that forms part of local pharmacopoeia of Mauritius and correlate any observed activity with its phytochemical profile. Aqueous and organic fractions of the leaves, fruits, and seeds of these plants were subjected to antimicrobial testing by the disc diffusion method against 8 clinical isolates of bacteria and 2 strains of fungus. It was found that MC, OT, and FF possessed antimicrobial properties against the test organisms. The MIC for MC ranged from 0.5 to 9 mg/mL and that of FF from 2 to 10 mg/mL and the lowest MIC value (0.5 mg/mL) was recorded for the unripe fruits of MC against E. coli. On the other hand, higher concentration of the unripe MC fruit extract of 9 mg/mL was needed to be effective against a resistant strain of Staphylococcus aureus,(MRSA). The antimicrobial effect against MRSA was lost upon ripening of the fruits. The methanolic extract of both MC and FF showed highest MIC values compared to the corresponding aqueous extract, which indicates the low efficacy and the need of higher doses of the plant extract. Phytochemical screening of the plants showed the presence of at least tannins, phenols, flavonoids, and alkaloids, which are known antimicrobial phyto-compounds. In conclusion, the observed antimicrobial properties would tend to further validate the medicinal properties of these commonly used endemic medicinal and food plants of Mauritius. [source] ChemInform Abstract: Synthesis and Antimicrobial Activities of Some New 3-(Chlorophenylethyl)-, 3-(Chlorophenylethenyl)-isocoumarins and Their Dihydro Derivatives.CHEMINFORM, Issue 17 2010Gul S. Khan Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Synthesis and Antimicrobial Activities of Novel Quinoline Derivatives Carrying 1,2,4-Triazole Moiety.CHEMINFORM, Issue 9 2010Sumesh Eswaran Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: A Convenient One-Pot Synthesis of Series of 3-(2,6-Diphenyl-4-pyridyl)hydroquinolin-2-one under Microwave Irradiation and Their Antimicrobial Activities.CHEMINFORM, Issue 24 2009Niraj K. Ladani Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Synthesis and Antimicrobial Activities of Some Novel 1,2,4-Triazolo[3,4-b]-1,3,4-thiadiazoles and 1,2,4-Triazolo[3,4-b]-1,3,4-thiadiazines Carrying Thioalkyl and Sulfonyl Phenoxy Moieties.CHEMINFORM, Issue 34 2007T. Karabasanagouda Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Synthesis, Insecticidal and Antimicrobial Activities of Some Heterocyclic Derivatives of Quinazolinone.CHEMINFORM, Issue 10 2007Tripti Singh Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Synthesis of Some New Quinoxalines and 1,2,4-Triazolo[4,3-a]quinoxalines for Evaluation of in vitro Antitumor and Antimicrobial Activities.CHEMINFORM, Issue 5 2007Soad A. M. El-Hawash Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Synthesis of Some Benzothiazepins and Their Antimicrobial Activities.CHEMINFORM, Issue 24 2003N. P. Shetgiri Abstract For Abstract see ChemInform Abstract in Full Text. [source] ChemInform Abstract: Synthesis and Structure Elucidation of Some New Thioether Derivatives of 1,2,4-Triazoline-3-thiones and Their Antimicrobial Activities.CHEMINFORM, Issue 17 2002N. N. Guelerman Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Synthesis and Antimicrobial Activities of Novel Naphtho[2,1-b]pyran, Pyrano[2,3-d]pyrimidine and Pyrano[3,2-e][1,2,4]triazolo[2,3-c]pyrimidine Derivatives.CHEMINFORM, Issue 17 2002Ahmed H. Bedair Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Palladium-Catalysed Amination of Electron-Deficient or Relatively Electron-Rich Benzo[b]thienyl Bromides , Preliminary Studies of Antimicrobial Activity and SARsEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 17 2004Maria-João R. P. Queiroz Abstract Several diarylamines in the benzo[b]thiophene series were prepared in good to high yields by palladium-catalysed amination of ethyl 3-bromobenzo[b]thiophene-2-carboxylate with anilines and 5-aminoindole in the presence of Pd(OAc)2, BINAP and Cs2CO3 in toluene. The presence of the ester group at the 2-position of the benzo[b]thiophene moiety increases the yields and lowers the heating times relative to the reactions performed with 3-bromobenzo[b]thiophene. When aminopyridines were used instead of anilines, the ligand and the solvent need to be changed to XANTHPHOS and dioxane in the amination reaction. With 2-aminopyridine a one-pot C,N coupling and intramolecular cyclization involving the nitrogen atom of the pyridine ring occurred, with loss of ethanol, giving an interesting fluorescent tetracyclic heteroaromatic compound. The antimicrobial activity, the minimal inhibitory concentrations (MICs) and the structure-activity relationships (SARs) were evaluated. A selectivity with low MICs was observed against Bacillus Cereus, and good results were also obtained against Candida albicans. The acids obtained by hydrolysis of the ester group, as non-proteinogenic ,,,-unsaturated ,-amino acids, can be incorporated into peptide chains to induce conformational constraints. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004) [source] Magnetically Controllable Silver Nanocomposite with Multifunctional Phosphotriazine Matrix and High Antimicrobial ActivityADVANCED FUNCTIONAL MATERIALS, Issue 14 2010Panagiotis Dallas Abstract A recently developed multi-functional phosphotriazine-based polymer is used as a matrix for embedding ,-Fe2O3 nanoparticles as well as a suitable chemical template for surface modification with silver nanoparticles. For the primary magnetic modification, maghemite nanoparticles are surface modified with oleic acid in order to render them organophilic and to prevent the aggregation of the nanoparticles. This aggregation could occur as the polymer synthesis, based on reaction of phosphonitrilic chlorine and 1,4-phenylenediamine, takes place in toluene. The surface active amine units of the polymer structure enable the reduction of silver cations to silver nanoparticles, which are well attached and finely dispersed on its surface. The developed nanocomposite represents one of the few magnetically controllable antibacterial agents based on silver nanoparticles. Magnetic measurements reveal the completely suppressed interactions among maghemite nanoparticles because of their perfect surface coating with an organic surfactant and fine dispersion inside the polymer matrix. This magnetic nanocomposite exhibits a high antibacterial and antifungal activity as proven by tests with nine bacterial strains and four candida (yeast genus) species. For the majority of the tested species, the minimum-inhibition concentrations are below 100,mg,L,1, which is comparable to their equivalent minimum-inhibition concentrations in colloidal silver systems. [source] Antimicrobial Activity of Silver Nanocrystals Encapsulated in Mesoporous Silica NanoparticlesADVANCED MATERIALS, Issue 17 2009Monty Liong Silver nanocrystals encapsulated in mesoporous silica nanoparticles are prepared by coating hydrophobic silver nanocrystals with amphiphilic surfactants and growing mesostructured silica around the materials. The nanoparticles can be used as antimicrobial agents for both Gram-positive and -negative bacteria through oxidative dissolution of the silver nanocrystals. The surface characteristics of the silica exterior affect the binding to the bacteria and the cytotoxicity. [source] Enhancing Physical Properties and Antimicrobial Activity of Konjac Glucomannan Edible Films by Incorporating Chitosan and NisinJOURNAL OF FOOD SCIENCE, Issue 3 2006Bin Li ABSTRACT: The antimicrobial effect of konjac glucomannan (KGM) edible ûlm incorporating chitosan (CHI) and nisin at various ratios or concentrations was studied. This activity was tested against pathogenic bacteria, namely, Escherichia coli, Staphylococcus aureus, Listeria monocytogenes, and Bacillus cereus. Mechanical and physical properties were determined, and the results indicated that the blend film KC2 (mixing ratio KGM 80/ CHI 20) showed the maximum tensile strength (102.8 ± 3.8 MPa) and good transparency, water solubility, and water vapor transmission ratio. Differential scanning calorimetry (DSC) and Fourier transform infrared (FTIR) spectroscopy were used to characterize the structural change of the blend films; and the results showed that strong intermolecular hydrogen bonds occurred between CHI and KGM. Incorporation of nisin at 463IU per disk of film for the selected KC2 was found to have antimicrobial activity against S. aureus, L. monocytogenes, and B. cereus. The mean value of inhibition zone diameter of the CHI-N series and the KC2-N series were higher than the KGM-N series at each corresponding concentration and with significant difference (P < 0.05), however, there was no significant difference in the antimicrobial effect between CHI and KC2 incorporating nisin. At all these levels, the blend ûlm KC2-nisin had a satisfactory appearance, mechanical and physical properties, and antimicrobial activity. Therefore, it could be considered as a potential "active" packaging material. [source] Synthesis and Biological Evaluation of 2-Mercapto-1,3-benzothiazole Derivatives with Potential Antimicrobial ActivityARCHIV DER PHARMAZIE, Issue 10 2009Carlo Franchini Abstract The enhancement of bacterial resistance of pathogens to currently available antibiotics constitutes a serious public health threat. So, intensive efforts are underway worldwide to develop new antimicrobial agents. To identify compounds with a potent antimicrobial profile, we designed and synthesized low molecular weight 2-mercaptobenzothiazole derivatives 2a,2l and 3a,3l. Both series were screened for in-vitro antibacterial activity against the representative panel of Gram-positive and Gram-negative bacteria strains. The biological screening identified compounds 2e and 2l as the most active ones showing an interesting antibacterial activity with MIC values of 3.12 ,g/mL against Staphylococcus aureus and 25 ,g/mL against Escherichia coli, respectively. The replacement of the S-H by the S-Bn moiety resulted in considerable loss of the antibacterial action of the 3a,3l series. The antibiotic action of compounds 2e and 2l was also investigated by testing their activity against some clinical isolates with different antimicrobial resistance profile. Moreover, the involvement of the NorA efflux pump in the antibacterial activity of our molecules was evaluated. Finally, in this paper, we also describe the cytotoxic activity of the most interesting compounds by MTS assay against HeLa and MRC-5 cell lines. [source] Synthesis and Antimicrobial Activity of Some Novel 2-[4-(Substituted Piperazin-/Piperidin-1-ylcarbonyl)phenyl]-1H -benzimidazole DerivativesARCHIV DER PHARMAZIE, Issue 1 2009Canan Kus Abstract In this study, we report the synthesis and antimicrobial evaluation of several new 4-(1H -benzimidazol-2-yl)benzamides (11,30) and 5-chloro-1-(p -fluorobenzyl)-2-{4-[(4-methylpiperazin-1-yl)carbonyl]phenyl}-1H -benzimidazole (33). Compound 20 exhibited the best antibacterial activity with MIC value of 6.25 ,g/mL against Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA). Significant antifungal activities were obtained with the compounds 13, 14, 18, 19, and 33 with MIC values of 3.12 ,g/mL which are close to fluconazole. [source] ChemInform Abstract: Microwave-Assisted Synthesis and Evaluation of Antimicrobial Activity of 3-{3-(s-Aryl and s-Heteroaromatic)acryloyl}-2H-chromen-2-one Derivatives.CHEMINFORM, Issue 24 2010Olayinka O. Ajani Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Synthesis and Antimicrobial Activity of 5-(2-Aminothiazol-4-yl)-3,4-dihydro-4-phenylpyrimidin-2(1H)-one (IV).CHEMINFORM, Issue 17 2010Kushal R. Lanjewar Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Synthesis and Antimicrobial Activity of 3-Propene 1,2-Benzisoxazole Derivatives.CHEMINFORM, Issue 1 2010R. A. Shastri Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Reaction of 3-Aminocyclohex-2-en-1-ones with Arylidenemalononitriles: Synthesis, Characterization and Antimicrobial Activity of Some New Quinoline Bearing Pyrazole Nucleus.CHEMINFORM, Issue 1 2010Nirav K. Shah Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Synthesis and Antimicrobial Activity of Some New Cyanopyridine and Cyanopyrans Towards Mycobacterium tuberculosis and Other Microorganisms.CHEMINFORM, Issue 42 2009D. H. Vyas Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Antimicrobial Activity of Novel Fused Nitrogen, Sulfur and Phosphorus Containing-Heterocycles and Relevant Phosphonates with Difurylpyridazine Species.CHEMINFORM, Issue 25 2009Wafaa M. Abdou Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Synthesis of New 3-Substituted-5- (2-hydroxyethyl)-3,4,5,6-tetrahydro-2H-1,3,5-thiadiazine-2-thione Derivatives with Potential Antimicrobial Activity.CHEMINFORM, Issue 41 2008Mostafa A. Hussein Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Synthesis and Antimicrobial Activity of Some New Pyrazolo[3,4-d]pyrimidines (IV) and Thiazolo[4,5-d]pyrimidines (VI).CHEMINFORM, Issue 30 2008J. D. Akbari Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: An Efficient Solventless Synthesis of ,-Aryl-N-[1-methyl-2-(2/4-chlorophenyl)]ethyl Nitrones and Their Antimicrobial Activity.CHEMINFORM, Issue 20 2008Chinnadurai Amutha Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Formation and Antimicrobial Activity of 2-Azetidinones from Selective Ester Cleavage in 1,3,3-Trisubstituted 4-[2,-(O-Diarylacyl)hydroxyphenyl]-2-azetidinones.CHEMINFORM, Issue 16 2008G. S. Singh Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Synthesis and Antimicrobial Activity of 4-Aryl-5-tetra-O-benzoyl-,-D-glucopyranosylimino-3-thio-1,2,4-dithi azolidines.CHEMINFORM, Issue 16 2008M. G. Dhonde Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] Environmentally Benign Synthesis of Fluorinated Pyrazolone Derivatives and Their Antimicrobial Activity.CHEMINFORM, Issue 46 2007S. N. Shelke Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] | ||||||||||||||||||||||||||||||||||||||||