Last Frontier (last + frontier)

Distribution by Scientific Domains


Selected Abstracts


Dispatches from the Last Frontier of Molecular and Cell Biology: Biosynthesis of Polysaccharides and Proteoglycans of the Cell Surface and Extracellular Matrix

IUBMB LIFE, Issue 4 2002
Bruce Stone
No abstract is available for this article. [source]


Editorial: At the Bifurcation of the Last Frontiers

JOURNAL OF INTERVENTIONAL CARDIOLOGY, Issue 4 2010
THACH NGUYEN M.D.
The concept of coronary angioplasty percutaneous coronary intervention (PCI) was pioneered by Andreas Gruntzig. Since then, several modifications, innovative devices, techniques, and advances have revolutionized the practice of interventional cardiology. Coronary bifurcation and chronic total occlusion are the last two frontiers that continue to challenge the skills of the interventional cardiologists. Proceedings of the second Bifurcation Summit held from November 26 to 28, 2009 in Nanjing, China are published in this symposium. In a general review, the state of the art in management of bifurcation lesion is summarized in the statement of the "Bifurcation Club in KOKURA." A new-presented concept was the "extension distance" between the main vessel and the sidebranch ostia and its association with restenosis. The results of two studies on shear stress (SS) after PCI showed that contradictory lower SS after stenting was associated with lower in-stent restenosis. There was better fractional flow reserve after double kissing crush technique than provisional one-stent technique. There was also lower rate of stent thrombosis after bifurcation stenting with excellent final angiographic results. In a negative note, the SYNTAX score had no predictive values on trifurcated left main stenting. In summary, different aspects of percutaneous management for bifurcated lesion are described seen from different perspectives and evidenced by novel techniques and strategies. (J Interven Cardiol 2010;23:293,294) [source]


Reptile toxicology: Challenges and opportunities on the last frontier in vertebrate ecotoxicology

ENVIRONMENTAL TOXICOLOGY & CHEMISTRY, Issue 10 2000
William A. Hopkins
No abstract is available for this article. [source]


Physical anthropology in the last frontier

EVOLUTIONARY ANTHROPOLOGY, Issue 4 2006
Jason M. Kamilar
No abstract is available for this article. [source]


State of the Art Review: Current Status of Topical Nasal Antimicrobial Agents,

THE LARYNGOSCOPE, Issue 6 2000
Yau Hong Goh FRCS
Abstract The nasal cavity and paranasal sinuses are probably one of the last frontiers in the head and neck region where the use of topical antimicrobial agents is not yet established. Although the anatomy of the nasal cavity and the paranasal sinuses can theoretically be exploited for the administration of antimicrobials in rhinosinusitis, very few studies have been conducted to test the feasibility of this mode of therapy. We review the anatomical and physiological factors that should be considered in the use of topical nasal antimicrobial agents and the current status of topical nasal antimicrobial usage, and we make recommendations for the administration of topical nasal antimicrobial agents. [source]