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Lamp Examination (lamp + examination)

Distribution by Scientific Domains
Medical Sciences100%

Kinds of Lamp Examination

  • slit lamp examination
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    Selected Abstracts

    In vivo corneal confocal microscopy in keratoconus

    OPHTHALMIC AND PHYSIOLOGICAL OPTICS, Issue 3 2005
    Joanna G. Hollingsworth
    Abstract Purpose:, To evaluate the corneas of keratoconic subjects using in vivo confocal microscopy. Methods:, Slit scanning confocal microscopy was used to evaluate the central cornea of one eye of each of 29 keratoconic subjects (mean age 31 ± 10 years; range 16,49 years). Quantitative aspects of corneal morphology were compared against data from control subjects. Results:, Compared with normal control corneas, epithelial wing cell nuclei were larger (p < 0.0001) and epithelial basal cell diameter was larger (p < 0.05) in the keratoconic cornea. Many of the keratoconic corneas investigated showed increased levels of stromal haze and reflectivity, which appeared to be related to the presence of apical scarring on slit lamp examination. A grading scale was devised to quantify the levels of haze. This scale was shown to provide a measure of the level of scarring present. The anterior keratocyte density (AKD) and posterior keratocyte density were 19% lower (p < 0.0001) and 10% lower (p = 0.004) than in controls, respectively. The reduction in AKD was significantly associated with three factors: a history of atopy, eye rubbing and the presence of corneal staining. The mean endothelial cell density in keratoconus was 6% greater than that of normal controls (p = 0.05). The level of endothelial polymegethism was shown not to be different between keratoconic subjects and matched controls (paired t -test: t = 1.82, p = 0.08). Conclusions:, Confocal microscopy demonstrates significant quantitative alterations of corneal morphology in keratoconus. [source]

    1361: Main anterior entities 2: granulomatous

    ACTA OPHTHALMOLOGICA, Issue 2010
    F WILLERMAIN
    Purpose During uveitis, inflammatory cells and epitheloid cells can aggregates on the corneal endothelium forming keratic precipitates (KPs). Methods On slit lamp examination, KP's can have different forms and locations. Once they are large with a mutton fat appearance, uveitis will be classified as granulomatous. Results Granulomatous uveitis is a heterogeneous group of disease with anterior, intermediate and panuveitis. Granulomatous uveitis can be due to several infectious and non infectious causes, but masquerade syndromes and idiopathic cases must also been ruled out. Conclusion This course will first describe the main clinical characteristics of those different entities. A standard work-up procedure will then be proposed. [source]

    Subconjunctival injection of bevacizumab (Avastin®) for corneal neovascularization

    ACTA OPHTHALMOLOGICA, Issue 2009
    MF DE LA PAZ
    Purpose to study the effects of subconjunctival injection of Bevacizumab on corneal neovascularization. Methods Prospective interventional case series on 7 eyes of 7 patients who underwent subconjunctival injection with Bevacizumab. The following parameters were studied pre-op, at 1 week, 30, 60 and 90 days post-op: UCVA, BCVA, pachymetry with OCT, slit lamp examination and photographic imaging. Conjunctival impression cytology pre-op at 1 week and 9o days was done and complications were also noted. Results Pre-op diagnoses were: herpetic leucoma (4 eyes), chemical burn (2 eyes), neurotrofic keratopathy (1 eye). An informed off-label consent form prior to procedure was signed. 1.25 mg of subconjunctival Bevacizumab was injected nearest the area affected. Mean preoperative UCVA and BCVA were 0.86 and 0.44 LogMar units, improved to 0.61 and 0.26 LogMar units at 90 days post-op, respectively. Central and peripheral pachymetry improved from 532 and 623 microns pre-op, to 529 and 619 microns at 90 days post-op, respectively. All slit lamp findings and photographic imaging showed a clear regression of superficial and deep stromal corneal vascularization, with clearing of lipid deposits around the affected areas. No toxic effects were noted on conjunctival impression cytology. Conclusion Subconjunctival injection of Bevacizumab is a safe and effective procedure for the regression of superficial and deep corneal neovascularization. It may be a good alternative for patients prior to performing an optical keratoplasty or for those who are poor candidates for the same. [source]

    Macular thickness alterations after cataract surgery determined by optical coherence tomography

    ACTA OPHTHALMOLOGICA, Issue 2009
    M ELEFTHERIADOU
    Purpose To evaluate macular thickness alterations with optical coherence tomography after phacoemulsification and posterior champer intraocular lens implantation. Methods In this prospective study,201 patients who underwent phacoemulsication(102 men and 99 women)with mean age 65±8years were included.Best corrected visual acuity,complete slit lamp examination with lens and OCT examination were performed in all patients before surgery and at one,three and six months postoperatively.Patients were divided into five groups:Group 1(control group-100 eyes):patients without any predisponding factors for cystoid macular edema,Group 2(15 eyes):patients with complicated surgery,Group 3(27 eyes):patients with epiretinal membrane,Group 4(35 eyes):patients with diabetes and Group 5(24 eyes):patients with glaucoma. Results The preoperative mean minimal foveal thickness(MMFT)in groups 1 and 2 was 204±24,m and 213±47,m respectively and had no significant changes throughout the follow up period(p>0,05). In groups 3,4 and 5 a significant increase of macular thickness was detected. In group 3 the preoperative MMTF was 248±72,m and at 1,3 and 6 months it was 263±86,m(p=0,01),240±30,m(p=0,18)and 270±64,m(p<0,01)respectively. In group 4 the preoperative MMTF was 219±39,m,after 1month the MMTF increased at 257±78,m(p=0,002),at 3months it was 231±46,m(p=0,005)and at the last examination at 6 months it was 236±49,m(p=0,005). In group 5 the initially MMTF(206±21,m)had significant increase in the first[213±30,m(p=0,07)]and in the third month[223±24,m(p=0,03)]. Conclusion Diabetic retinopathy, epiretinal membranes and glaucoma may predispose to increase in macular thickness after cataract surgery. [source]

    Microplasmin improves surgical outcome in a rabbit model for trabeculectomy

    ACTA OPHTHALMOLOGICA, Issue 2009
    E VANDEWALLE
    Purpose This study was designed to study the efficacy and safety of Microplasmin as an anti-scarring agent after trabeculectomy in a rabbit model. Methods The effect of Microplasmin was investigated in vivo in a rabbit model for glaucoma surgery. Clinical outcome measures were intra-ocular pressure, bleb area and survival, side effects on slit lamp examination. Moreover, (immuno-) histochemical analysis of the eyes was performed, with quantification of inflammation (CD 45) and collagen deposition (Trichrome and Sirius Red). In the first experiment (n=10), Microplasmin anterior chamber injection was compared to placebo injection. In the second experiment (n=3), topical Microplasmin drops were compared to placebo drops. In the third experiment (n=5) the combination of Microplasmin anterior chamber injection and topical drops was compared to placebo injection and drops. All experiments were conducted in a masked observator way. Results Microplasmin significantly augmented the bleb area and survival in a rabbit model of trabeculectomy after a single anterior chamber injection or combination therapy (injection combined with drops) compared to control. Collagen deposition was borderline reduced after Microplasmin administration compared to control. No significant changes in inflammation were noticed in the anterior chamber or in the conjunctiva. Conclusion Microplasmin single injection or combination with postoperative drops improved the outcome after trabeculectomy. In a rabbit model, larger blebs were produced for a longer period compared to control, and collagen deposition tended to decrease in this small series. [source]

    Slitlamp integrated OCT, what you can see, is what you can scan

    ACTA OPHTHALMOLOGICA, Issue 2009
    FD VERBRAAK
    Purpose To present results of OCT images captured of the posterior and anterior segment of the eye using the SLSCAN-1, a new FD-OCT device integrated into a slit lamp. Methods Patients, seen in the outpatient clinic of the Academic Medical Center, were scanned with the SLSCAN-1, a newly developed OCT scanning device, integrated into a common slit lamp (figure 1). The OCT is a Fourier Domain OCT system (SLD light source, central wavelength 830 nm, bandwidth 30 nm, 1024 pixel CCD camera, scan speed 5k A-scans per second, 1024 A-scans per B-scan). The posterior segment scans have been captured using a standard indirect ophthalmic lens (Volk). A color fundus photography of the observed area is made at the same time (Topcon camera DC1, resolution = 3.24 Mp). Results For posterior segment imaging, the flexible optical arrangement of the slit lamp and the hand-held lens (Volk), allows the user to scan large areas of the retina (>45 degrees), depending on the pupil size of the patient. In all patients the macula and optic disk could be visualized without any difficulty. In the anterior segment mode, the SLSCAN-1 allows imaging of the cornea, anterior chamber, iris and parts of the lens. Conclusion The images made by the SLSCAN-, new slit lamp integrated FD-OCT, could be very useful to examine patients directly, both posterior and anterior, during regular slit lamp examinations. Commercial interest [source]