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Laboratory Research (laboratory + research)
Selected AbstractsHealthy Stranded Animals and Laboratory ResearchMARINE MAMMAL SCIENCE, Issue 3 2008Paul E. Nachtigall No abstract is available for this article. [source] Psychophysiological and Neurobiological Concomitants of Mindfulness: Evidence from Laboratory ResearchPSYCHOPHYSIOLOGY, Issue 2010Article first published online: 5 AUG 2010 First page of article [source] Effects of maternally transferred organochlorine contaminants on early life survival in a freshwater fishENVIRONMENTAL TOXICOLOGY & CHEMISTRY, Issue 10 2005Thomas A. Johnston Abstract Laboratory research has shown that female fish can pass toxic organochlorines (OCs) from their bodies to their eggs, killing their offspring if sufficient quantities are transferred. We conducted a controlled incubation study using gametes from a wild, OC-contaminated walleye (Sander vitreus) population (Bay of Quinte, Lake Ontario, Canada) in order to assess among-female variation in offspring early life survival in relation to ova concentrations of planar OCs (polychlorinated dibenzo- p -dioxins and furans and planar polychlorinated biphenyls) and a suite of other maternal and ova characteristics. Equal volumes of ova from each female were fertilized, pooled, and incubated together as an experimental cohort. Relative survival of each female's offspring was estimated as the proportion of surviving larvae (at ,5 d posthatch) that she contributed to the cohort as determined by microsatellite DNA parentage assignment. Total planar OC concentration (expressed as toxic equivalency of 2,3,7,8-tetrachloro-dibenzo- p -dioxin) of ova was positively related to maternal age and size and to ova lipid content. However, early life survival did not decline with increasing ova planar OC concentrations. Similarly, we observed no significant relationships between early life survival and ova thiamine content, ova fatty acid composition, or maternal age or size. Early life survival was more strongly correlated with date of spawn collection, thyroid hormone status of the ova, and ovum size. Maternally transferred planar OCs do not appear to negatively influence female reproductive success in this walleye population. [source] Explaining Jury Verdicts: Is Leniency Bias for Real?JOURNAL OF APPLIED SOCIAL PSYCHOLOGY, Issue 10 2004Dennis J. Devine Laboratory research suggests juries that begin deliberation with a strong majority (i.e., 2/3 or more) usually end up choosing the verdict favored by this majority, whereas those without a strong majority generally acquit or hang. We tested the robustness of these findings in the field by examining trial and deliberation correlates of jury verdicts using data from 79 criminal jury trials held in Indiana. As expected, several trial characteristics and the first-vote preference distribution were related to jury verdicts. However, there was no evidence of leniency bias,75% of those juries without a 2/3 majority on the first deliberation vote ended up convicting. Contributions of the study, limitations, and alternative explanations for the observed severity bias are discussed. [source] Recent advances in the neurophysiology of chronic painEMERGENCY MEDICINE AUSTRALASIA, Issue 1 2005Kylie Baker Abstract The chronic pain syndrome patient has become the ,leper' of emergency medicine. There are no emergency medicine guidelines and minimal research into managing this challenging group of patients. Objective:, To summarize the recent advances in laboratory research into the development of chronic pain that have relevance to emergency management. When the level of supporting evidence is low, it is imperative that emergency physicians understand the physiology that underpins those expert opinions upon which they base their treatment strategies. Methods:, Literature was searched via Medline, Cochrane, Cinahl, and PsycINFO from 1996 to 2004, under ,chronic pain and emergency management'. Medline from 1996 was searched for ,chronic pain and prevention', ,chronic pain and emergency' and ,chronic pain'. Bibliographies were manually searched for older keynote articles. Results:, Advances in understanding the biochemical changes of chronic pain are paralleled by lesser known advances in delineation of the corticol processing. Conclusions:, Drug manipulation causes complex action and reaction in chronic pain. Emergency physicians must also optimize cognitive and behavioural aspects of treatment to successfully manage this systemic disease. [source] IBD and skeletal health: Children are not small adults!INFLAMMATORY BOWEL DISEASES, Issue 11 2005Francisco A Sylvester MD Abstract Patients with inflammatory bowel disease often have decreased bone mass, and fragility fractures can occur. Multiple disease- and treatment related factors, including malnutrition, inflammation, malabsorption, decreased weight-bearing physical activity, and corticosteroids negatively influence bone metabolic activity. Because low-impact fracture is the pathologic expression of critically reduced bone mass and bone quality, knowing the relative risk of fractures in patients with IBD is of great interest. The absolute risk for incident fractures in these patients is still being debated. Clinical and laboratory research is clarifying mechanisms by which IBD can affect the function of osteoblasts and osteoclasts. In this concise review, we aim to provide an update on this topic, with focus on how pediatric IBD affects bone health. [source] University of San Diego palynological investigation of the Dos Cabezas giantsINTERNATIONAL JOURNAL OF OSTEOARCHAEOLOGY, Issue 5 2003P. S. Geyer Abstract Beginning in 1999, coprolite soil samples were collected from the skeletal remains of Moche giants excavated at the archaeological site of Dos Cabezas, northern Peru. In 2000, a pilot palynological study was undertaken to ascertain if pollen was recoverable from them. The results of this study encouraged us to form a student team to continue the laboratory research. It was also decided to sample as many of the excavated skeletal remains from the giants' tombs as possible. Following the 2001 field season a palynological study was performed on the three individuals (one adult giant and two children) recovered from Tomb 3 in 1999. Pollen was extracted and analysed. The combined results of this archaeobotanical study are significant and in one instance have led us into insights into the possible causes of death of these three contemporaneous internments. This report represents only the preliminary results of this ongoing research. Copyright © 2003 John Wiley & Sons, Ltd. [source] Contexts and experimentalism in the psychology of Gabriele Buccola (1875,1885)JOURNAL OF THE HISTORY OF THE BEHAVIORAL SCIENCES, Issue 2 2007Silvia Degni Gabriele Buccola, since his untimely death, often has been mentioned as the first Italian psychologist who developed a strict program of laboratory research. Buccola, a Sicilian of Albanian ancestry, is a "case" in the history of Italian psychology. A self-taught positivist, he established a relation with the major representatives of the European positivism. Kraepelin mentions him as one of the precursors of his project of applying experimental psychology to psychopathology. Buccola actually carried out research on the psychological, chemical-biological, and psychopathological "modifiers" of reaction times, following an experimental program dealing mainly with the differential study both of basic and superior psychological processes, with mental hygiene ends. Historians of psychology agree in considering Buccola the first Italian laboratory psychologist to plan a program of research that was close to European psychological experimentalism. The present article, starting from an outline of Buccola's role in the rising Italian scientific psychology, recontextualizes his experimentalism in an international sphere. This operation, which is carried out through a careful survey of Buccola's entire production,both theoretical and more properly scientific,is based on the search of the Darwinian, Spencerian, and Haeckelian evolutionist themes emerging from Buccola's program of research,a program that was influenced by the variegated European experimental panorama and characterized by the vision of science as a knowledge capable of transforming the nature of man and of society. © 2007 Wiley Periodicals, Inc. [source] Glucocorticoid regulation of the inflammatory response to injuryACTA ANAESTHESIOLOGICA SCANDINAVICA, Issue 7 2004M. P. Yeager During the first half of the 20th century, physiologists were interested in the adrenal glands primarily because adrenalectomized animals failed to survive even mild degrees of systemic stress. It eventually became clear that hormones secreted by the adrenal cortex were critical for survival and, in this context, adrenal cortical hormones were widely considered to support or stimulate important responses to stress or injury. With the purification and manufacture of adrenal cortical hormones in the 1930s and 1940s, clinicians suddenly discovered the potent anti-inflammatory actions of glucocorticoids (GCs). This dramatic, and unexpected, discovery has dominated clinical and laboratory research into GC actions throughout the second half of the 20th century. More recent research is again reporting GC-induced stimulatory effects on a variety of inflammatory response components. These effects are usually observed at low GC concentrations, close to concentrations that are observed in vivo during basal, unstimulated states. For example, GC-mediated stimulation has been reported for the hepatic acute-phase response, for cytokine secretion, expression of cytokine/chemokine receptors, and for the pro-inflammatory mediator, macrophage migration inhibition factor. It seems clear that the long-held clinical view that GCs act solely as anti-inflammatory agents needs to be re-assessed. Varying doses of GCs do not lead simply to varying degrees of inflammation suppression, but rather GCs can exert a full range of effects from permissive to stimulatory to suppressive. [source] The implication of laboratory research on tooth wear and erosionORAL DISEASES, Issue 1 2005D Bartlett [source] Cognitively impaired older adults exhibit comparable difficulties on naturalistic and laboratory prospective memory tasksAPPLIED COGNITIVE PSYCHOLOGY, Issue 6 2009Christine M. Will Prospective memory, or remembering future intentions, is critical for independent living for all ages, but especially older adults. Previous laboratory research has found that cognitively impaired older adults may have particular difficulties with prospective memory, but previous studies have not examined whether these difficulties occur in everyday life. In normal ageing, a dissociation between settings has been observed, with older adults selectively impaired in laboratory (but not naturalistic) contexts. Consequently, in the present study 15 cognitively impaired older adults were compared to demographically matched controls on laboratory and naturalistic measures of prospective memory. The results indicated that the cognitively impaired group performed more poorly on both measures, with the magnitude of the deficit comparable across setting. These results indicate that for older adults who present with cognitive impairment prospective memory deficits observed in laboratory settings may be a valid indicator of difficulties experienced executing delayed intentions in everyday life. Copyright © 2008 John Wiley & Sons, Ltd. [source] Strategies for the capture and transport of bonefish, Albula vulpes, from tidal creeks to a marine research laboratory for long-term holdingAQUACULTURE RESEARCH, Issue 13 2009Karen J Murchie Abstract Throughout their circumtropical distribution, bonefish (Albula spp.) play a vital role in local economies as a highly prized sport fish. Recent interest in stock enhancement to sustain bonefish fisheries has led to the recognition that there currently are no data on how to live capture large numbers of adults (potential broodstock), transport them to captive facilities and how to handle them to ensure high survival. The objective of this study was to develop strategies for the capture and relocation of wild bonefish to a marine research holding facility to enable basic research and explore the potential for culturing bonefish for stock enhancement. Bonefish Albula vulpes (Linnaeus, 1758) were captured as they entered or left tidal creeks on Eleuthera, The Bahamas using seine nets and then transported by boat or truck to the laboratory. The relocation process evoked secondary stress responses at the metabolic, osmoregulatory and haematological levels as indicated by changes in blood glucose, lactate, haematocrit and ion values, relative to control fish. Physical and behavioural disturbances were also observed in bonefish that were unable to acclimate to laboratory conditions. Successful laboratory acclimation and long-term holding of wild bonefish was achieved through an adaptive learning process, whereby we identified a series of strategies and handling techniques to facilitate the acclimation of wild adult bonefish to captivity. This knowledge will enable future laboratory research on bonefish and is a prerequisite to the culture of this highly prized sport fish, and other sub-tropical and tropical marine species. 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