Key Applications (key + application)

Distribution by Scientific Domains

Selected Abstracts

Capillary electrophoresis-electrospray-mass spectrometry in peptide analysis and peptidomics

Miguel Herrero
Abstract In the present work, an exhaustive review of the main developments and applications of CE-MS for peptide analysis is given. This review includes the use of different CE separation modes, MS analyzers, capillary coatings, preconcentration techniques, on-chip applications as well as other different multidimensional strategies for peptide analysis. Key applications are critically discussed and relevant works published from January 2000 to May 2007 are summarized including information concerning the type of sample, CE-MS parameters as well as some figures of merit of the different CE-MS procedures developed for peptide analysis and peptidomics. [source]

Chitosan Films Doped with Gold Nanorods as Laser-Activatable Hybrid Bioadhesives

Paolo Matteini
Biocompatible chitosan/gold nanorods films are fabricated and tested as laser-activatable adhesives. When exposed to near-infrared laser light the nanoparticles carry out efficient photothermal conversion, which activates the polar groups of chitosan strands and mediates functional adhesion with a biological tissue. This technology may enable a number of key applications in medicine including tissue repair, wound dressing and drug delivery. [source]

Ultrafast imaging: Principles, pitfalls, solutions, and applications

Jeffrey Tsao PhD
Abstract Ultrafast MRI refers to efficient scan techniques that use a high percentage of the scan time for data acquisition. Often, they are used to achieve short scan duration ranging from sub-second to several seconds. Alternatively, they may form basic components of longer scans that may be more robust or have higher image quality. Several important applications use ultrafast imaging, including real-time dynamic imaging, myocardial perfusion imaging, high-resolution coronary imaging, functional neuroimaging, diffusion imaging, and whole-body scanning. Over the years, echo-planar imaging (EPI) and spiral imaging have been the main ultrafast techniques, and they will be the focus of the review. In practice, there are important challenges with these techniques, as it is easy to push imaging speed too far, resulting in images of a nondiagnostic quality. Thus, it is important to understand and balance the trade-off between speed and image quality. The purpose of this review is to describe how ultrafast imaging works, the potential pitfalls, current solutions to overcome the challenges, and the key applications. J. Magn. Reson. Imaging 2010;32:252,266. 2010 Wiley-Liss, Inc. [source]

Biodoped Ceramics: Synthesis, Properties, and Applications

Smita Y. Gadre
This feature article focuses on biodoped ceramics. These are inorganic materials in which biological materials are incorporated, thus adding new functionality to them. A brief overview of the prominent synthesis techniques for biodoped ceramics, with emphasis on modified sol,gel processes for metal oxide matrices, is given first. Theoretical treatments of the encapsulation of biologicals within a porous ceramic matrix are reviewed. Experimental studies of the stability and dynamics of protein entrapment in silica and other ceramic matrices are also discussed. Finally, key applications of biodoped ceramics in biochemical species detection, bio-catalysis, and drug delivery are presented. [source]

The Midas Touch: Surface Processing With the UV Excimer Laser

Drive Disruptive Innovations, Open Up Growth Markets
Very much like the ancient king Midas who as the legend tells was able to transform ordinary material into gold by the touch of his hand, today's excimer lasers are capable of transforming an unspecificmaterial layer into a high value, functional surface by their unique beam properties. Representing today's most cost-effective and dependable pulsed, ultraviolet (UV) laser technology, excimer lasers enable disruptive innovation in various growth industries as diverse as the markets for flat panel displays, automobiles, biomedical devices and alternative energies. It is the combination of two fundamental aspects, namely wavelength and output power, which determines the excimer laser's unique value adding potential in high tech industries which more than ever have to balance product size-efficiency and performance demands with process speed and production costs. This article will try to provide an insight into some key applications of the excimer laser. [source]