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Intravitreal Triamcinolone Acetonide (intravitreal + triamcinolone_acetonide)

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Medical Sciences100%

Terms modified by Intravitreal Triamcinolone Acetonide

  • intravitreal triamcinolone acetonide injection
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    Selected Abstracts

    Macular function after intravitreal triamcinolone acetonide injection for diabetic macular oedema

    ACTA OPHTHALMOLOGICA, Issue 5 2010
    Murat Karacorlu
    Abstract. Purpose:, We aimed to evaluate the effect of intravitreal triamcinolone acetonide (IVTA) on macular function in patients with diabetic macular oedema (DMO). Methods:, Eleven eyes in 11 patients with DMO were enrolled. In each eye, at baseline and at 30 days after IVTA injection, logMAR visual acuity (VA), macular sensitivity, fixation stability and fixation location by MP-1 microperimetry and optical coherence tomography (OCT) foveal thickness were assessed. Results:, Thirty days after IVTA injection, eyes with DMO showed a significant (p < 0.001) reduction in foveal thickness and significant (p < 0.01) increases in logMAR VA and MP-1 retinal sensitivity (p < 0.001). There was also significant (p = 0.046) improvement in fixation location and some improvement in fixation stability, although the latter was not significant (p = 0.08). Conclusions:, In eyes with DMO, short-term improvement in retinal sensitivity and fixation properties can be achieved by IVTA injection. [source]

    Effects of repeated injection of intravitreal triamcinolone on macular oedema in central retinal vein occlusion

    ACTA OPHTHALMOLOGICA, Issue 3 2009
    Lili Wang
    Abstract. Purpose:, To investigate the effectiveness of repeated injections of intravitreal triamcinolone acetonide (IVTA) in the treatment of macular oedema caused by central retinal vein occlusion (CRVO). Methods:, Seventeen pseudophakic or aphakic eyes of 17 patients (10 male, seven female) with macular oedema caused by CRVO received a repeat injection of 4 mg IVTA, 16 weeks after the first injection of the same dose. The examination included measurements of best-corrected visual acuity (BCVA) for distance and central foveal thickness (CFT) by optical coherence tomography (OCT), preoperatively and 1, 2, 3 and 4 months postoperatively. The values were compared by paired- t test. Side-effects were monitored. Results:, BCVA and CFT were not significantly different before initial and repeat injections. Transient improvements of BCVA and CFT were achieved after both injections. At the end of follow-up, BCVA and CFT were significantly different compared to pre-injection values in the same group (P = 0.032, 0.049 in the initial-injection group and P = 0.001, 0.008 in the repeat-injection group, respectively). However, compared to the initial injection, BCVA measurements were significantly worse at each time-point (P = 0.043, 0.011, 0.010 and 0.012, respectively) after the repeat injection, as were CFT at 1, 2 and 3 months post-injection (P = 0.040, 0.015 and 0.025, respectively). The achieved maximum mean intraocular pressures were 20.00 [standard deviation (SD) 2.06] mmHg and 18.56 (SD 3.65) mmHg after the first and repeat injections, respectively. These values were not significantly different (P = 0.467). No other significant adverse events were noted during the study. Conclusion:, A repeat injection of 4 mg IVTA may not be as effective as an initial injection for the treatment of macular oedema caused by CRVO. [source]

    Repeated intravitreal triamcinolone acetonide for chronic sympathetic ophthalmia

    ACTA OPHTHALMOLOGICA, Issue 3 2006
    Jost B. Jonas
    No abstract is available for this article. [source]

    Psoriatic uveitis-associated cystoid macular oedema treated with intravitreal triamcinolone acetonide

    ACTA OPHTHALMOLOGICA, Issue 3 2006
    Luna Dhir
    No abstract is available for this article. [source]

    Neovascular glaucoma treated by intravitreal triamcinolone acetonide

    ACTA OPHTHALMOLOGICA, Issue 5 2003
    Jost B. Jonas
    No abstract is available for this article. [source]

    Factors associated with variability in response of diabetic macular oedema after intravitreal triamcinolone

    CLINICAL & EXPERIMENTAL OPHTHALMOLOGY, Issue 6 2009
    MRCOphth, Shaheeda Mohamed MPH
    Abstract Purpose:, To identify factors associated with variability in anatomical and functional response of diabetic macular oedema (DMO) after 4 mg of intravitreal triamcinolone acetonide (ivTA), and for recurrence of macular oedema. Design:, Pooled analysis of individual data from two randomized controlled trials. Methods:, This was a multicentre study involving 107 eyes with DMO administered 4 mg ivTA. Predictive factors for response to treatment were evaluated with linear regression analysis. Factors associated with time to recurrence of oedema were studied with Cox proportional hazards modelling. Main outcome measures were maximum improvement in optical coherence tomography (OCT)-measured central foveal thickness (CFT) and best-corrected visual acuity (BCVA), final CFT and BCVA at 12 months and time to oedema recurrence. Results:, Greater reduction of retinal thickening occurred in eyes with worse baseline thickening (P < 0.001). There was also greater improvement of visual acuity in eyes with poorer preoperative BCVA levels (P < 0.001). Age, duration of oedema and previous macular laser treatment had no significant effect on maximal BCVA or CFT improvement. Eyes given 4 mg triamcinolone alone were more likely to develop recurrence of oedema at 12 months than those given a combination of 4 mg triamcinolone plus sequential laser (hazard ratio 2.60 [95% confidence interval: 1.45,4.67]). Conclusion:, Baseline OCT-measured retinal thickening and BCVA are important predictors of maximal anatomical and functional response of DMO to ivTA, respectively. Combination treatment strategy using sequential laser therapy may have a role in delaying recurrence of oedema after triamcinolone. [source]

    Use of intravitreal triamcinolone acetonide injection in unilateral idiopathic juxtafoveal telangiectasis

    CLINICAL & EXPERIMENTAL OPHTHALMOLOGY, Issue 5 2005
    Kenneth KW Li MRCS
    Abstract Idiopathic juxtafoveal telangiectasis (IJT) is one of the primary retinal telangiectasia that can result in visual impairment attributed to resultant cystoid macular oedema and rarely, choroidal neovascularization. The authors herein report successful treatment using intravitreal triamcinolone acetonide in a case of unilateral IJT that did not respond to prior laser photocoagulation. Serial optical coherence tomography was used to monitor the effectiveness of intravitreal triamcinolone acetonide in the treatment of IJT. [source]