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And Development (and + development)
Kinds of And Development Terms modified by And Development Selected AbstractsInnovation and Knowledge Management: The Long ViewCREATIVITY AND INNOVATION MANAGEMENT, Issue 3 2001Michael Lester The challenge of the e,Economy is one of technological change and the innovation process affords insights into how this new knowledge can be harnessed across the economy to increase productivity and generate wealth. The conceptual framework for this paper is National Systems of Innovation (NSI) as applied to Australia Edquist (1997); Freeman (1995). NSI allows us to take a holistic view of innovation that realistically blends technology with institutional elements, particularly including issues of collaboration. Taking a Long View (Schwartz (1991), that is, looking back on the legacy of experience with the innovation process, will also facilitate looking forward strategically from Australia's current practices, and to speculate on the prospects. This paper illustrates selectively and not comprehensively, from my own direct experience, the evolution of innovation policies in Australia and speculates on their implications for collaboration in the e,Economy by drawing on selected case studies in Research and Development, Industry and Trade, and the e,Economy. It also draws upon work for my doctorate in knowledge management at the University of Technology. The selection and synthesis of theory inevitably also reflect, however idiosyncratically, my academic training in engineering, politics and economics. [source] Trials update in walesCYTOPATHOLOGY, Issue 2007A. Fiander Three ongoing studies will be presented and discussed. Prevalence of Human Papillomavirus Infection in a South Wales Screening population Methods: A total of 10 000 consecutive, anonymous liquid based cytology screening samples were collected over a five month period in 2004. Age, cytology result and social deprivation score was provided for each specimen. The methodology was chosen to ensure inclusion of all women attending routine cervical screening, avoiding potential constraints associated with obtaining individual informed consent. The liquid based cytology samples were processed and reported by the receiving cytology laboratory and the residual specimens sent to the HPV Research Laboratory, Wales College of Medicine, where they were processed and stored at -80°C until analysis. High risk and low risk HPV Typing was undertaken using PCR , EIA (Jacobs et al 1997). Full high risk typing was performed on HPV positive specimens. Results: The study population had a mean age of 38 years with 92% negative, 5% borderline and 3% dyskaryotic cytology. The average social deprivation score was 17.4 (based upon the Welsh Index of multiple deprivation). The following results will be presented: HPV prevalence by age. HPV prevalence by cytology result. Type specific HPV prevalence in single and multiple infection. Conclusion: This study represents the largest type specific HPV Prevalence Study in the UK to date. As such it will form a useful base line against which to access performance of marketed HPV tests and evaluating the impact following implementation of HPV vaccination. [Funded by Welsh Office for Research and Development] CRISP , 1 Study (Cervical Randomized Intervention Study Protocol -1) Background: Indole-3-carbinol (I3C) and Diindolylmethane (DIM) are found in cruciferous vegetables and have been identified as compounds that could potentially prevent or halt carcinogenesis. I3C spontaneously forms DIM in vivo during acid digestion. I3C has been shown to prevent the development of cervical cancer in HPV 16 transgenic mice and both I3C and DIM have been shown to promote cell death in cervical cancer cell models. DIM is the major active bi-product of I3C and preliminary data indicate that DIM is active in cervical dysplasia and may be better tolerated than I3C. Aim: To investigate chemoprevention of high grade cervical neoplasia using Diindolylmethane (DIM) supplementation in women with low grade cytological abnormalities on cervical cytology. Objectives: To observe any reduction in the prevalence of histological proven high-grade cervical intraepithelial neoplasia (CIN) after 6 months of supplementation. ,,To observe any reduction in the prevalence of cytological abnormalities. ,,To observe any changes in the clinical appearance of the cervix. To assess acceptability and monitor any side effects of DIM supplementation. ,,To assess whether any benefit is seen in relation to Human Papillomavirus (HPV) status including HPV Type, Viral load and integration. Methods: This is a double blind randomized placebo-controlled trial involving 600,700 women with low grade cytological abnormalities on a cervical smear. Randomization is in the ratio of 2 : 1 in favour of active medication. Women with first mildly dyskaryotic smear or second borderline smear are eligible. They are asked to take two capsules daily for 6 months. At the end of 6 months they undergo repeat cervical cytology, HPV testing and colposcopy. Results: A progress report will be given for this ongoing study. [Funded: - Cancer Research UK] Type Specific HPV Infection in Welsh Cervical Cancers Background: Whilst there have been numerous studies of HPV infection associated with cervical cancer and on prevalence of Human Papillomavirus in diverse populations there have been no studies of these variables in the same population. Against a background of prophylactic HPV vaccination it is important to assess potential protection against cervical cancer within a given population. The most comprehensive analysis of HPV type specific cervical cancer is a meta-analysis published by the IARC in 2003. This however included only three UK based studies, totalling 118 cases, 75 of which were only investigated by HPV type PCR for four high risk types. None of this data was presented with associated population based prevalence data. Therefore, the research objectives for this study in combination with the first study above, are as follows: To determine the frequency of specific HPV types in cervical cancers in Wales. To compare the distribution of specific HPV types amongst cervical cancers with their prevalence in the general population. This will allow accurate delineation of the relationship between prevalence of specific HPV types in the general population and their association with clinically relevant disease. This information is a pre-requisite to assess the potential impact of prophylactic vaccination against HPV infection in Wales. Methods: Welsh Cervical Cancer specimens from 2000,2005 will be identified from pathology departments within Wales. The pathology of each tumour will be reviewed by a single Gynaecological Pathologist. The age of the patient and pathological features of the tumour will be noted. DNA will be extracted from the paraffin sections and HPV typed by PCR-EIA. Results: A progress report will be given for this ongoing study. [Funded by Welsh Office for Research and Development] [source] Ecological research in the office of research and development at the U.S. Environmental Protection Agency: An overview of new directions,,ENVIRONMENTAL TOXICOLOGY & CHEMISTRY, Issue 4 2000Rick A. Linthurst Abstract In virtually every major environmental act, Congress has required that the U.S. Environmental Protection Agency (U.S. EPA) ensure not only that the air be safe to breathe, the water safe to drink, and the food supply free of contamination, but also that the environment be protected. In response, the U.S. EPA's Office of Research and Development (ORD) has established research to improve ecosystem risk assessment and management, identifying it as one of the highest priority research areas for investment over the next 10 years. The research is intended to provide environmental managers with new tools and flexible guidance that reflect a holistic environmental management perspective of science and that can be applied both to common and unique problems. In keeping with its responsibility to provide the U.S. EPA with science that supports a dynamic changing regulatory agenda, the ORD has set the goal of its Ecological Research Program to "provide the scientific understanding required to measure, model, maintain and/or restore, at multiple scales, the integrity and sustainability of ecosystems now, and in the future." In the context of this program, ecological integrity is defined in relative terms as the maintenance of ecosystem structure and function characteristic of a reference condition deemed appropriate for its use by society, and sustainability is defined as the ability of an ecosystem to maintain relative ecological integrity into the future. Therefore, the research program will emphasize relative risk and consider the impact of multiple stressors, at multiple scales and at multiple levels of biological organization. The program will also shift from chemical to biological and physical stressors to a far greater extent than in the past. The purpose of this paper is to provide an introduction to the U.S. EPA's changing ecological research program. [source] Cocaine Rapid Efficacy Screening Trial (CREST): a paradigm for the controlled evaluation of candidate medications for cocaine dependenceADDICTION, Issue 2005Deborah B. Leiderman ABSTRACT Aim Development of effective medications for the treatment of cocaine dependence remains a major priority for the National Institute on Drug Abuse (NIDA) at the National Institutes of Health. The Cocaine Rapid Efficacy Screening Trial (CREST) paradigm was developed by the Division of Treatment Research and Development (DT R&D) at NIDA with the goal of enhancing pilot clinical trial validity when systematically assessing a range of medications and drug classes for potential utility in treatment of cocaine dependence. Design CREST utilizes a randomized, controlled, parallel group, blinded methodology for comparing one or more marketed medications against a standard, pharmaceutical grade placebo. The trial design is comprised of a flexible 2,4-week screening/baseline period followed by randomization to an 8-week treatment period. Measures Standard measures of outcomes for the CREST included urinary benzoylecgonine (primary metabolite of cocaine), retention, cocaine craving, depression, clinical global impression and HIV-risk behaviors. In order to facilitate comparisons of data from the CREST studies across sites, drug classes and time, standardized procedures, measures and psychosocial counseling were used. Results A total of 19 medications were evaluated in out-patient treatment research clinics in Boston, Cincinnati, Los Angeles, New York and Philadelphia. Conclusions Findings supported decisions to move forward three medications (cabergoline, reserpine, tiagabine) using full-scale, adequately powered, randomized placebo-controlled trial designs. Lessons learned from the CREST experience continue to shape cocaine pharmacotherapy trial design and execution. [source] Cocaine Rapid Efficacy Screening Trials (CREST): lessons learnedADDICTION, Issue 2005Kyle M. Kampman ABSTRACT Aims The Cocaine Rapid Efficacy Screening Trials (CREST) were designed by the National Institute on Drug Abuse Division of Treatment Research and Development (NIDA, DT R&D) to rapidly screen a number of medications potentially useful for the treatment of cocaine dependence. Design Each CREST trial was designed to compare several medications in a single trial against an unmatched placebo. The placebo group was included in each trial to avoid the nearly universal positive response to medications seen in open-label trials. In addition, a common set of procedures and outcome measures were employed throughout to increase comparability of results obtained from different trials and from different times. Participants In all, 18 medications were screened in seven different trials, conducted in four different sites throughout the United States involving 398 cocaine-dependent patients. Findings Three medications were found to be promising enough to include in subsequent larger trials. Common statistical procedures for evaluating medications were developed to facilitate comparisons across sites and across time. A portion of the data were pooled and analyzed, which yielded some useful insights into cocaine dependence and its treatment. Finally, a review of individual trials together with the pooled analysis revealed several potential improvements for future screening trials. Conclusions Overall, the CREST trials proved to be useful for rapidly screening medications for treatment of cocaine dependence, but several modifications in design should be made before this framework is applied further. [source] Mathematical modelling of fire development in cable installationsFIRE AND MATERIALS, Issue 4 2001P. Van Hees In 1996 DG XII of the European Commission (Research and Development) approved a 3 year project on the fire performance of electrical cables. Within this FIPEC project, a major part of the work involved correlation and mathematical modelling of flame spread and heat release rate in cable installations. The FIPEC project has developed different levels of testing ranging from a small-scale, cone calorimeter test procedures developed for cables and materials, a full-scale-test procedure based on the IEC 60332-3, but utilizing HRR and SPR measurements, and a real scale test conducted on model cable installations. Links through statistical correlations and mathematical fire modelling between these levels were investigated and the findings are presented in this paper. These links could form the scientific foundations for standards upon which fire performance measurements can be based and for new fire engineering techniques within fire performance based codes. Between each testing level correlation, numerical and mathematical models were performed. All of the models were based on the cone calorimeter test method. The complexity of the models varied from correlation models to advanced physical pyrolysis models which can be used in CFD codes. The results will allow advanced prediction of cable fires in the future. Also a bench mark was established for the prediction of cable performance by means of data obtained from the constituent materials. Copyright © 2002 John Wiley & Sons, Ltd. [source] A study of best practices in training transfer and proposed model of transferHUMAN RESOURCE DEVELOPMENT QUARTERLY, Issue 2 2008Lisa A. Burke Data were gathered from a sample of training professionals of an American Society of Training and Development (ASTD) chapter in the southern United States regarding best practices for supporting training transfer. Content analysis techniques, based on a rigorous methodology proposed by Insch, Moore, & Murphy (1997), were used to analyze the rich data. Findings suggest that interventions for bolstering training transfer are best carried out in the work context and design and delivery phase, take place after training or during, and involve trainers and supervisors. Activities garnering top attention from trainers as best practices include (starting with most frequently reported) supervisory support activities, coaching, opportunities to perform, interactive training activities, transfer measurement, and job-relevant training. Several new transfer variables also emerged from the data, indicating existing transfer models can be further refined. Ultimately, we propose a refined model of transfer to extend human resource development (HRD) theory in the area of transfer. [source] A Strategy for Nursing Research and DevelopmentINTERNATIONAL JOURNAL OF NURSING PRACTICE, Issue 1 2001David R Thompson Professor No abstract is available for this article. [source] Evaluating Corporate Training and Development: An Indian ExperienceINTERNATIONAL JOURNAL OF TRAINING AND DEVELOPMENT, Issue 4 2001P. S. Yadapadithaya The central purpose of this article is to report on the current practices of evaluating training and development programs in the Indian corporate sector. The data were collected from written questionnaires mailed to 252 respondent companies,127 private, 99 public, and 26 multinational corporations (MNCs). The results and discussions are based on the major drivers and key result areas of training and development; purposes, levels, instruments, timing, and designs of evaluation; serious limitations of the training system; and finally the major challenges currently faced by the Indian corporate sector in strengthening the training and development function. [source] Training and Development in the People's Republic of ChinaINTERNATIONAL JOURNAL OF TRAINING AND DEVELOPMENT, Issue 3 2001Jinyu Xie First page of article [source] Exploratory factor analysis of the research and development culture index among qualified nursesJOURNAL OF CLINICAL NURSING, Issue 9 2005Bill Watson MSc Aims and objectives., This paper presents the exploratory factor analysis of a rating instrument for assessing the strength of organizational Research and Development (R&D) culture. Background., Despite nursing's limited research capacity, the discipline is capitalising upon opportunities to become involved in research and is making strong progress. Within the context of the debate on nursing research capacity, the R&D Culture Index was developed as a means of appraising R&D culture within health care organizations. Design., Factor analysis was carried out on data collected from 485 nursing staff. The method of extraction was Principal Components Analysis with oblique rotation. Methods., The Index was developed from the findings of qualitative research conducted with NHS staff. Eighteen items, encompassing the main themes from the data, were initially included in the Index. This pilot instrument was distributed to nursing staff within three different types of NHS Trust. Factor analysis resulted in rejection of two items and the analysis was repeated using the remaining 16 items. Results., Three latent factors were extracted accounting for 58·0% of the variance in the data. The factors were: R&D Support, describing the perceived support within the working environment for R&D activity; Personal R&D Skills and Aptitude, describing an individual's perception of their ability towards R&D activity; and Personal R&D Intention, describing an individual's willingness to engage in R&D activity. Each factor had good internal reliability, as did the overall index. Conclusion., The R&D Culture Index provides an efficient means of assessing the strength of an organization's R&D culture in a way that captures the role of the individual practitioner and the organizational environment. Relevance to practice., These findings suggest that the continuing promotion of R&D within health care organizations is dependent upon a multi-faceted approach that addresses the learning needs of the organization as well as those of the individual practitioners. [source] Growth and Development with Special Reference to Developing Countries by A. P. Thirlwall (Palgrave Macmillan: London, 2003, 7th edn, pp. xxviii + 816.JOURNAL OF INTERNATIONAL DEVELOPMENT, Issue 8 20032nd edn, Macroeconomics for Developing Countries by Raghbendra Jha (Routledge: London, pp. xi + 496). No abstract is available for this article. [source] Does the Capitalization of Development Costs Improve Analyst Forecast Accuracy?JOURNAL OF INTERNATIONAL FINANCIAL MANAGEMENT & ACCOUNTING, Issue 1 2010Evidence from the UK It has been documented that investments in Research and Development (R&D) are associated with increased errors and inaccuracy in earnings forecasts made by financial analysts. These deficiencies have been generally attributed to information complexity and the uncertainty of the future benefits of R&D. This paper examines whether the capitalization of development costs can reduce analyst uncertainty about the future economic outcome of R&D investments, provide outsiders with a better matching of future R&D-related revenues and costs, and therefore promote accuracy in analyst forecasts. UK data is used, because accounting rules in the United Kingdom permitted firms to conditionally capitalize development costs even before the introduction of the International Financial Reporting Standards. The choice to expense R&D rather than conditionally capitalize development costs is found to relate positively to signed analyst forecast errors. This finding is robust to controlling for the influence of other factors that may affect errors, as well as for the influence of R&D investments on forecast errors. The decision to capitalize versus expense is not observed to have a significant influence on analyst forecast revisions. The findings are interpreted as evidence that the choice to capitalize as opposed to expense may help to reduce deficiencies in analyst forecasts; hence, is informative for users of financial statements. Increased informativeness is expected to have repercussions for the effectiveness with which analysts produce earnings forecasts, and, as a result, market efficiency. [source] Recollections of Irving H. Sher 1924,1996: Polymath/information scientist extraordinaireJOURNAL OF THE AMERICAN SOCIETY FOR INFORMATION SCIENCE AND TECHNOLOGY, Issue 14 2001Eugene Garfield Over a 35-year period, Irving H. Sher played a critical role in the development and implementation of the Science Citation Index® and other ISI® products. Trained as a biochemist, statistician, and linguist, Sher brought a unique combination of talents to ISI as Director of Quality Control and Director of Research and Development. His talents as a teacher and mentor evoked loyalty. He was a particularly inventive but self-taught programmer. In addition to the SCI,® Social Sciences Citation Index,® and Arts and Humanities Citation Index,® Sher was involved with the development of the first commercial SDI system, the Automatic Subject Citation Alert, now called Research Alert,® and Request-A-Print Cards. Together we developed the journal impact factor and the Journal Citation Reports.® Sher was also the inventor of the SYSTABAR System of coding references and Sherhand. He was involved in key reports on citation-based historiography, forecasting Nobel prizes, and served as a referee for JASIS over a 20-year period. [source] Craniofacial skeletal deviations following in utero exposure to the anticonvulsant phenytoin: monotherapy and polytherapyORTHODONTICS & CRANIOFACIAL RESEARCH, Issue 1 2003HI Orup Jr Structured Abstract Authors , Orup Jr HI, Holmes LB, Keith DA, Coull BA. Objective , To identify and quantify the craniofacial effects from prenatal exposure to phenytoin monotherapy and polytherapy using cephalometric, hand-wrist, and panoramic radiographs and to determine if such deviations persist with age. Design , Craniofacial structures of 28 anticonvulsant-exposed individuals were evaluated using 20 landmarks in lateral cephalometric radiographs and 19 landmarks in frontal cephalometric radiographs. Skeletal maturity was assessed using hand-wrist radiographs. Dental maturity and the presence of dental anomalies were evaluated using panoramic radiographs. Eleven individuals were re-evaluated 7 years later, on average, to determine the persistence of any measured deviations. Setting and Sample Population , Department of Growth and Development, Harvard School of Dental Medicine and Massachusetts General Hospital. Patients were recruited from several sources. Outcome Measure , The evaluated dimensions included linear, angular, and proportional measures. Results , The most common deviations were decreased height and length of the maxilla, decreased length of the posterior cranial base, length of the mandible, cranial width and level of the cribriform plate, and a decrease in the Wits Appraisal assessment. The deviations were more significant in the polytherapy-exposed individuals than in the monotherapy-exposed individuals. These deviations, especially in the maxilla, persisted with age as revealed in a re-evaluation of 11 individuals. Conclusion , The craniofacial skeletal findings among individuals exposed in utero to phenytoin monotherapy or phenytoin polytherapy, when considered in aggregate, suggest a mild pattern of maxillary hypoplasia that becomes more pronounced with age. [source] Preface: phys. stat. sol. (c) 1/10PHYSICA STATUS SOLIDI (C) - CURRENT TOPICS IN SOLID STATE PHYSICS, Issue 10 2004Eun-Kyung Suh The Fifth International Symposium on Blue Laser and Light Emitting Diodes (ISBLLED-2004) was held in Gyeongju, Korea from 15,19 March 2004. Gyeongju, the ancient capital of the thousand-year Silla kingdom (57 B.C. to 935 A.D.) provided additional pleasure to the participants as an exceptional open-air museum with antique treasures scattered all around the city. During the last decade we have witnessed remarkable developments in wide-gap semiconductors and light emitting devices in the spectral range from the visible to deep UV. The purpose of the Symposium was to provide a forum for intensive discussion on the issues and main progress especially in optoelectronic devices, material growth and characterization, and quantum structures of wide bandgap semiconductors. A total of 243 papers including 220 contributed and 23 invited ones were presented and discussed by 487 participants from 17 countries world-wide. Among them, 154 manuscripts were submitted and reviewed by the usual evaluation process of physica status solidi. Some were rejected or withdrawn, and finally 139 papers are published in the special issues of physica status solidi (a), (b), and (c). We gratefully acknowledge the referees for their careful review. The papers are grouped into 7 categories. The subheadings and the number of papers in each are as follows: Optoelectronic devices, 43; Growth and characterization, 45; Nano and quantum structures, 21; Contacts, 8; Zinc oxide, 9; Indium nitride and indium rich InGaN, 6; Others, 7. The special session of the Symposium, "The LED Highlight", designed partially to meet the challenging targets of the technology, i.e., energy savings and clean environment preservation, drew much attention and is edited as a special coloured section in this issue. The next symposium is scheduled for Montpellier, France, in 2006. We wish the organizers of that symposium the best of luck and hope to see all of the ISBLLED-2004 participants again at ISBLLED-2006. ISBLLED-2004 was sponsored by The Research Society for the Wide-gap Semiconductors, Korean Physical Society, Office of Naval Research, Korea Science and Engineering Foundation, Korea Research Foundation, Korea Association for Photonics Industry Development, Asian Office of Aerospace Research and Development, and Korea Photonics Technology Institute. We would like to thank Ms. E. S. Hwang for her devotion to the preparation and the Proceedings of the symposium including the manuscript handling for publication. [source] Integrating art as a trans-boundary element in a radical innovation frameworkR & D MANAGEMENT, Issue 1 2010Christian Stüer Companies have learned that radical innovations (RIs) are a prerequisite to grow organically. However, companies struggle to identify and introduce RIs, as their inherent high uncertainties and novelty challenge established organisations and management routines. To address the first challenge, companies need to take a holistic approach and design a trans-boundary environment of creativity, trans-disciplinary and entrepreneurial spirit. This environment attracts and retains visionary people, fosters generation of new opportunities and cultivates adaptability. By adapting evaluation metrics for RI, setting up flexible processes, and promoting trans-disciplinary exchange, the second challenge can be addressed. Increased research has concentrated on several aspects of RI lately, but so far a combining framework is missing. Our paper bridges this gap by developing an improved theoretical framework, enhancing the existing literature and introducing art as a method to advance trans-disciplinary interchange. In a case-study approach, we have applied our framework to the research and development department of Vodafone Research and Development, Germany, as they integrate art methodically in their research and development process. Analysing their RI capabilities, we identify the trans-disciplinary exchange with artists as a novel initiator and driver of RI, which has not yet been adequately considered. [source] Steady-state field-scale gas permeability estimation and pore-gas velocity calculation in a domain open to the atmosphereREMEDIATION, Issue 4 2000Dominic C. Digiulio Field-scale estimation of gas permeability and subsequent computation of pore-gas velocity profiles are critical elements of sound soil venting design. It has been our experience, however, in U.S. Environmental Protection Agency's (EPA's) technical assistance program, provided by the Office of Research and Development in support EPA regional offices, that many venting practitioners are unaware of equations and data interpretation methods appropriate for gas permeability estimation and pore-gas velocity computation. To ameliorate this situation, we use data collected at a U.S. Coast Guard Station in Traverse City, Michigan, to demonstrate gets permeability estimation and pore-gas velocity calculation for steady-state, axisymmetric, two-dimensional gas flow in a domain open to the atmosphere. For gas permeability estimation, we use random guesses constrained with decreasing intervals of radial and vertical permeabilityand analysis of root mean square errors to ensure attainment of a global versus local minimum. We demonstrate confidence in permeability estimation by providing plots of observed versus simulated pressure response. Finally, we illustrate how plots of pore-gas velocity as a function of distance and flow rate can be helpful in venting design. [source] STOCK MARKET VALUATIONS OF R&D AND ELECTRONICS FIRMS DURING TAIWAN'S RECENT ECONOMIC TRANSITIONTHE DEVELOPING ECONOMIES, Issue 1 2006CHAOSHIN CHIAO G12; O33 The objective of the present study is to investigate the market valuation of Research and Development (R&D) investments in the Taiwanese stock market from July 1988 to June 2002. The motivation stems from Taiwan's recent economic transition from a labor-intensive, then to a capital-intensive, and currently to a technology-based economy. The results support not only the existence, but also the persistence of R&D-associated mispricing. More importantly, it has become stronger as the electronics industry gradually dominates the economy. First, R&D-intensive stocks tend to outperform stocks with little or no R&D. Second, the R&D-intensity effect cannot fully be attributed to firm size. Third, the R&D-intensity effect is more pronounced for firms in the electronics industry after 1996. [source] Introduction: Aid and DevelopmentTHE ECONOMIC JOURNAL, Issue 496 2004John Hudson First page of article [source] Growth and Development of a Body of Knowledge: 16 Years of New Product Development Research, 1989,2004,THE JOURNAL OF PRODUCT INNOVATION MANAGEMENT, Issue 3 2008Albert L. Page In this study, a content analysis was performed on 815 articles focused on new product development (NPD) published in 10 selected leading marketing, management, NPD, and research and development (R&D) journals from 1989 to 2004. Journals selected were a combination of leading journals in the discipline and publications that included NPD articles. NPD articles were classified by a series of key attributes including methodology employed, domains of knowledge utilized, and broad topics explored. The resulting data were then studied to discern trends over time or common characteristics within domains, methodologies, or journals. The study of NPD has grown since the Journal of Product Innovation Management (JPIM) was launched in 1984. This study shows strong growth in the number of articles on NPD in each category of journal selected. The research in the articles has changed: The early focus on a few selected success factors or a staged development process has evolved and broadened over the 16-year period. More variables and more sophisticated models are being studied in NPD articles. The study found a continuing evolution in research topics and increased sophistication in quantitative techniques over the 16-year period. Overall this review of the NPD literature uncovers encouraging signs of a maturing discipline. However, there are concerns about continuing issues in methodology, insufficient study of service innovation, and continued focus on process characteristics instead of other antecedents of NPD success. The service sector seems to be understudied, even as the reality of a service economy is generally acknowledged. The call in a recent meta-analysis to focus more on market and product characteristics and less on process characteristics has not yet been heeded, even by marketing researchers. [source] FROM EXPERIENCE: Creating Synergy between Marketing and Research and Development,THE JOURNAL OF PRODUCT INNOVATION MANAGEMENT, Issue 1 2004Gail L. Rein The tensions between marketing and research and development (R&D) are so common that we have come to accept them as the way organizations are. If we remain resigned like this, how will we ever reap some of the benefits that can accrue from these groups working better together? If we can improve the working relationships between marketing and R&D, researchers promise a variety of desirable organizational outcomes, such as cycle-time reduction and new product success. This article describes in detail the changes that a Fortune 500 company made to its product development process to foster synergy between marketing and R&D. The modified process formalized the roles of marketing and R&D at both the front and back ends of the product development process, increasing productive interaction between the groups. The company found that at the front end, marketing and R&D needed to work together (1) to clarify the market requirements implicit in the market attack plan and (2) to develop a technical strategy that responded to the market requirements and that consequently implemented the market attack plan. At the back end, the groups needed to work together (3) to formulate the value messages used to market the company's products. The synergy created between marketing and R&D through the new process is credited for enabling the company to compete successfully in a market it never before had entered. [source] Research and Development, Regional Spillovers and the Location of Economic ActivitiesTHE MANCHESTER SCHOOL, Issue 4 2004Alberto Franco Pozzolo I present an endogenous growth model that studies the effects of local inter-industry and intra-industry knowledge spillovers in R&D on the allocation of economic activities between two regions. The equilibrium is the result of a tension between a centripetal force, the cost of transporting goods from one region to the other, and a centrifugal force, the cost increase associated with life in a more crowded area. The presence of local knowledge spillovers, which determines the concentration of the R&D activities within one region, also introduces a further centripetal force that makes a symmetric allocation of the economic activities impossible. The concentration of R&D fosters the equilibrium rate of growth of the economy with respect to the case of no-integration, by increasing the positive effect of local knowledge spillovers. Contrary to the findings of the majority of models in the new economic geography literature, within this framework a reduction in transport costs may be associated with a more even geographical distribution of economic activities. [source] Assessment of Bone Mineralization Following Renal Transplantation in Children: Limitations of DXA and the Confounding Effects of Delayed Growth and DevelopmentAMERICAN JOURNAL OF TRANSPLANTATION, Issue 3 2001Mary B. Leonard Pediatric renal transplantation recipients have numerous risk factors for decreased bone mass, including the underlying renal disease, nutritional deficits, decreased physical activity, inflammation and exposure to steroid therapy. The assessment of bone mineralization in children following renal transplantation is fraught with difficulty. Dual energy x-ray absorptiometry (DXA) is the most commonly employed tool to assess bone mineralization. However, DXA has important limitations in children and in individuals with renal disease. This brief review will examine the expected gains in bone size and bone mass during growth and the mechanisms by which renal failure and steroid therapy interrupt these process. In addition, the limitations of DXA for detecting impaired bone mineralization in children with renal disease are reviewed and alternative approaches explored. [source] Transformative Education: Chronicling a Pedagogy for Social ChangeANTHROPOLOGY & EDUCATION QUARTERLY, Issue 1 2008Miguel Guajardo This article chronicles the work of the Llano Grande Center for Research and Development, an educational nonprofit organization in South Texas, by following the narrative of one of its students and two of the authors, who are also founders of Llano Grande. Through the use of ethnography, visuals, and storytelling, they present an emerging theory of practice and a hybrid methodology that has contributed to the development of the work, the school, and the community. An activist agenda informed by practice and supported with theory is woven through the text in biographical form. The text also documents the cornerstones of the work: building strong relationships; work originating from self, place, and community; and engaging in meaningful work. When integrated into a seamless practice, this combination of guiding principles yields a certain power that youth and adults alike begin to negotiate within and between their peers, teachers, and community for change. This sense of self, efficacy, and power then informs much of their work as adults.,[Latino epistemology and education, activist ethnography, Llano Grande Center, storytelling, community as text, pedagogy of hope] [source] Camouflage as Aesthetic SustainabilityARCHITECTURAL DESIGN, Issue 6 2006Dagmar Richter Abstract A textile approach to architecture offers unique opportunities to explore a structure's surface and texture. Through a discussion of the history of the technique of camouflage and her own projects with Design Research and Development (DR_D), Dagmar Richter demonstrates the potential for surface enrichment to exceed mere ornament or patterning. A ,performative texture', camouflage interacts with its context mimicking the natural and effectively disguising whatever it covers. With a now long military association, camouflage also provides anything but a neutral background for its cover. Copyright © 2006 John Wiley & Sons, Ltd. [source] The Need for International Communications in Artificial Organs Research and Development and Clinical PracticeARTIFICIAL ORGANS, Issue 1 2004Paul S. Malchesky D.Eng. No abstract is available for this article. [source] Fractionation technology for the petroleum refining industryASIA-PACIFIC JOURNAL OF CHEMICAL ENGINEERING, Issue 4 2007Albert Hug Abstract Distillation Research and Development is moving rapidly with the utilization of computational fluid dynamic (CFD) modeling. Previously, a potential fractionation application would first be developed and fabricated. Then many hours of pilot plant testing would be required to finalize the design. The time line for the development of new distillation equipment has been reduced, leading to advances in fractionation equipment. Current applications of trays, packings, distributors and feed inlets can be optimized utilizing CFD modeling. CFD Modeling has improved the current generation of fractionation equipment. This modeling is also particularly important in maximizing capacity in tower revamps where the diameter of the tower is fixed. This paper will review the current-generation fractionation equipment and the utilization of the same in the petroleum refining industry. Copyright © 2007 Curtin University of Technology and John Wiley & Sons, Ltd. [source] GOLD infrastructure for virtual organizationsCONCURRENCY AND COMPUTATION: PRACTICE & EXPERIENCE, Issue 11 2008P. Periorellis Abstract The paper discusses the GOLD project (Grid-based Information Models to Support the Rapid Innovation of New High Value-Added Chemicals) whose principal aim is to carry out research and development into enabling technologies to support the formation, operation and termination of virtual organizations. The paper discusses the outcome of this research, which is the GOLD Middleware infrastructure. The infrastructure has been implemented in the form of a set of Middleware components, which address issues such as trust, security, contract monitoring and enforcement, information management and coordination. We discuss all these issues in turn and more importantly we demonstrate how current WS standards can be used to implement these issues. In addition, the paper follows a top down approach starting with a brief outline on the architectural elements derived during the requirements engineering phase and demonstrates how these elements were mapped onto actual services that were implemented according to service-oriented architecture principles and related technologies. Copyright © 2008 John Wiley & Sons, Ltd. [source] The Impact of R&D Intensity on Demand for Specialist Auditor Services,CONTEMPORARY ACCOUNTING RESEARCH, Issue 1 2005JAYNE M. GODFREY Abstract The audit fee research literature argues that auditors' costs of developing brand name reputations, including top-tier designation and recognition for industry specialization, are compensated through audit fee premiums. Audited firms reduce agency costs by engaging high-quality auditors who monitor the levels and reporting of discretionary expenditures and accruals. In this study we examine whether specialist auditor choice is associated with a particular discretionary expenditure - research and development (R&D). For a large sample of U.S. companies from a range of industries, we find strong evidence that R&D intensity is positively associated with firms' choices of auditors who specialize in auditing R&D contracts. Additionally, we find that R&D intensive firms tend to appoint top-tier auditors. We use simultaneous equations to control for interrelationships between dependent variables in addition to single-equation ordinary least squares (OLS) and logistic regression models. Our results are particularly strong in tests using samples of small firms whose auditor choice is not constrained by the need to appoint a top-tier auditor to ensure the auditor's financial independence from the client. [source] | |||||||||||||||||||||||||||||||||||||||||||||||||