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Important Ways (important + way)
Kinds of Important Ways Selected AbstractsPerfusion-based functional magnetic resonance imaging,CONCEPTS IN MAGNETIC RESONANCE, Issue 1 2003Afonso C. Silva Abstract The measurement of cerebral blood flow (CBF) is a very important way of assessing tissue viability, metabolism, and function. CBF can be measured noninvasively with magnetic resonance imaging (MRI) by using arterial water as a perfusion tracer. Because of the tight coupling between neural activity and CBF, functional MRI (fMRI) techniques are having a large impact in defining regions of the brain that are activated due to specific stimuli. Among the different fMRI techniques, CBF-based fMRI has the advantages of being specific to tissue signal change, a critical feature for quantitative measurements within and across subjects, and for high-resolution functional mapping. Unlike the conventional blood oxygenation level dependent (BOLD) technique, the CBF change is an excellent index of the magnitude of neural activity change. Thus, CBF-based fMRI is the tool of choice for longitudinal functional imaging studies. A review of the principles and theoretical backgrounds of both continuous and pulsed arterial spin labeling methods for measuring CBF is presented, and a general overview of their current applications in the field of functional brain mapping is provided. In particular, examples of the use of CBF-based fMRI to investigate the fundamental hemodynamic responses induced by neural activity and to determine the signal source of the most commonly used BOLD functional imaging are reviewed. © 2003 Wiley Periodicals, Inc. Concepts Magn Reson 16A: 16,27, 2003 [source] The metacommunity concept: a framework for multi-scale community ecologyECOLOGY LETTERS, Issue 7 2004M. A. Leibold Abstract The metacommunity concept is an important way to think about linkages between different spatial scales in ecology. Here we review current understanding about this concept. We first investigate issues related to its definition as a set of local communities that are linked by dispersal of multiple potentially interacting species. We then identify four paradigms for metacommunities: the patch-dynamic view, the species-sorting view, the mass effects view and the neutral view, that each emphasizes different processes of potential importance in metacommunities. These have somewhat distinct intellectual histories and we discuss elements related to their potential future synthesis. We then use this framework to discuss why the concept is useful in modifying existing ecological thinking and illustrate this with a number of both theoretical and empirical examples. As ecologists strive to understand increasingly complex mechanisms and strive to work across multiple scales of spatio-temporal organization, concepts like the metacommunity can provide important insights that frequently contrast with those that would be obtained with more conventional approaches based on local communities alone. [source] Uptake and accumulation of sediment-associated 4-nonylphenol in a benthic invertebrate (Lumbriculus variegatus, freshwater oligochaete)ENVIRONMENTAL TOXICOLOGY & CHEMISTRY, Issue 5 2005Valeria Croce Abstract In the present work, the oligochaete Lumbriculus variegatus was exposed for 56 d to lake sediment spiked with 4-nonylphenol (4-NP), which is a breakdown product of alkylphenol polyethoxylates, an important class of nonionic surfactants. During the exposure period, the content of 4-NP was determined in the oligochaetes, sediment, overlying water, and pore water in order to monitor the distribution of the 4-NP in the compartments of the test system. Concentration of 4-NP in L. variegatus increased linearly over the course of the test, with an uptake rate coefficient of 1.9 × 10,2 (± 0.2 × 10,2; [g carbon/(g lipid-h)]). No steady state was reached at the end of the exposure period, suggesting that the elimination of 4-NP by the organism was negligible. Ingested sediments played an important role in the accumulation of 4-NP in L. variegatus, which may achieve very high 4-NP body concentrations. The 56-d biota sediment accumulation factor (BSAF) was 24 ± 7 g carbon/g lipid. L. variegatus also was exposed to 4-NP-contaminated field sediment, and field oligochaetes and sediments were collected for 4-NP pollution assessment in aquatic ecosystem. The 4-NP uptake with natural sediment was in accordance with that measured with spiked sediments, suggesting that the bioavailability of sediment-associated 4-NP for L. variegatus was not affected by 4-NP sediment concentration and abiotic sediment characteristics. The BSAFs measured in field oligochaetes, ranging from 39 to 55 g carbon/g lipid, was relatively higher than the bioaccumulation factor measured in laboratory tests. The results suggest that 4-NP concentration can reach high levels in benthic oligochaetes; this can be an important way of exposure for their pelagic predators. [source] Importance of rhizodeposition in the coupling of plant and microbial productivityEUROPEAN JOURNAL OF SOIL SCIENCE, Issue 4 2003Eric Paterson Summary Plant roots influence the biological, chemical and physical properties of rhizosphere soil. These effects are a consequence of their growth, their activity and the exudation of organic compounds from them. In natural ecosystems, the linkages between inputs of carbon from plants and microbial activity driven by these inputs are central to our understanding of nutrient cycling in soil and the productivity of these systems. This coupling of plant and microbial productivity is also of increasing importance in agriculture, where the shift towards low-input systems increases the dependence of plant production on nutrient cycling, as opposed to fertilizers. This review considers the processes by which plants can influence the cycling of nutrients in soil, and in particular the importance of organic inputs from roots in driving microbially mediated transformations of N. This coupling of plant inputs to the functioning of the microbial community is beneficial for acquisition of N by plants, particularly in low-input systems. This occurs through stimulation of microbes that produce exoenzymes that degrade organic matter, and by promoting cycling of N immobilized in the microbial biomass via predation by protozoa. Also, plants increase the cycling of N by changes in exudation in response to nitrogen supply around roots, and in response to browsing by herbivores. Plants can release compounds in exudates that directly affect the expression of genes in microbes, and this may be an important way of controlling their function to the benefit of the plant. [source] The Hidden Politics of Administrative Reform: Cutting French Civil Service Wages with a Low-Profile InstrumentGOVERNANCE, Issue 1 2007PHILIPPE BEZES The article addresses internal and hidden politics of changes in bureaucracies by focusing on the introduction and use of policy instruments as institutional change without radical or explicit shifts in administrative systems. Beneath public administrative reforms, it examines the use of "low-profile instruments" characterized by their technical and goal-oriented dimension but also by their low visibility to external actors due to the high complexity of their commensurating purpose and the automaticity of their use. The core case study of the paper offers a historical sociology of a technique for calculating the growth of the French civil service wage bill from the mid-1960s to the 2000s. The origins, uses, and institutionalisation of this method in the French context are explored to emphasize the important way of governing the bureaucracy at times of crisis through automatic, unobtrusive, incremental, and low-profile mechanisms. While insisting on the salience of techniques for calculating, measuring, classifying, and indexing in the contemporary art of government, it also suggests the need for observing and explaining "everyday forms of retrenchment" in bureaucracies. [source] The reward of public service: nineteenth-century testimonials in contextHISTORICAL RESEARCH, Issue 208 2007Simon Morgan Testimonials were a ubiquitous form of public ritual in nineteenth-century Britain, and probably the most important way in which individual public service was recognized and rewarded. This article charts the emergence, development and decline of the testimonial, using accounts in the press, biographies and privately printed pamphlets. By placing them in their cultural context, it demonstrates the complex patterns of meaning that could be developed through these rituals, and uses them to throw new light on the controversy over paternalism and deference in factory culture, arguing that the role of testimonial occasions in that culture has been fundamentally misunderstood. [source] Using economic instruments to overcome obstacles to in situ conservation of biodiversityINTEGRATIVE ZOOLOGY (ELECTRONIC), Issue 1 2006Jeffrey A. McNEELY Abstract The leading direct cause of the loss of biodiversity is habitat alteration and disruption. If we are to address this cause directly, we need to find ways of changing the behavior of rural people. Experience has shown that this is done most effectively through the use of economic instruments, ranging from taxes that discourage over-exploitation, to direct payments for conservation activities carried out by rural land-owners or those occupying the land. In many parts of the world, governments provide incentives such as tax breaks to private land-owners. Other countries recognize specific use rights on particular parts of the land, enabling the land-owners to earn appropriate benefits. Since many protected areas have resident human populations, it is especially important that they be encouraged to contribute to the objectives of the protected area, and economic incentives offer an important way of doing so; they might, for example, be given employment in the protected area or in associated tourism activities. Direct payments to farmers for conserving watersheds is becoming increasingly popular, in both developed and developing countries. Improved conservation will require both removing perverse subsidies and developing a wide range of approaches for rewarding land-owners for biodiversity conservation activities. [source] A Pentecostal Way of Doing Theology: Method and MannerINTERNATIONAL JOURNAL OF SYSTEMATIC THEOLOGY, Issue 3 2007KENNETH J. ARCHER This article emphasizes the necessity of doing Pentecostal theology by means of an integrative methodology and in a narrative manner that flows out of Pentecostal identity. Pentecostal theology must move beyond the impasse created by subsuming its identity under the rubric of ,Evangelical' in order for it to articulate a vibrant fully orbed mature Pentecostal theology. This can be accomplished only when ,Pentecostal' is taken seriously as an authentic Christian tradition with its own view of reality. I argue that one very important way of articulating a Pentecostal theology in keeping with its identity is to ground it pneumatologically and organize it around the Five-fold Gospel. [source] Discounting decision for enterprises with high fixed cost and low variable costINTERNATIONAL TRANSACTIONS IN OPERATIONAL RESEARCH, Issue 2 2006Ping Hui Hsu Abstract Higher sales are the key to increased profit, especially for low variable cost industries. The use of quantity discount to promote business is an important way to increase sales. This study evaluates the use of discount, prepaid, multiple-purchase credit to increase sales. The purpose is to develop a strategy to maximize the unit revenue by simultaneously determining the discount rate and utility. A numerical example and sensitivity analysis are given to illustrate the theory. [source] Residential Provision for Adult Persons with Intellectual Disabilities in IrelandJOURNAL OF APPLIED RESEARCH IN INTELLECTUAL DISABILITIES, Issue 2 2007Fiona Mulvany Background, The type of accommodation provided for persons with an intellectual disability is a major indicator of the social policy for this client group. This is likely to vary within and across countries; hence the importance of undertaking national and international comparisons. Estimations of future need are also required to assist service planning. Method, A database of all persons in receipt of intellectual disability services has been operating in the Republic of Ireland since 1995. In Northern Ireland, regional databases were used to provide similar information. Results, Around 10 000 people live in some form of residential provision: 56% in special settings, 35% in ordinary housing and 9% in hospitals. Most residents were classed as having ,severe' disabilities and were aged over 35 years. There were marked differences in the amount and type of provision provided in the two parts of the island. This was also mirrored in differences across health service areas within each country. The demand for future places was greater in Northern Ireland. Conclusions, A planning target of 3.5 places per 1000 adult population is proposed although substantial investments in services is required to achieve this. Longitudinal surveys are an important way of monitoring the impact of new policy initiatives. [source] Negative consequences of community group participation for women's mental health and well-being: Implications for gender aware social capital buildingJOURNAL OF COMMUNITY & APPLIED SOCIAL PSYCHOLOGY, Issue 3 2009Katy Osborne Abstract Participation in community groups is argued to be an important way to create health-promoting social capital. However, relatively little attention has been paid to the ways in which gender affects the health promotion potential of participation. This paper reports on a qualitative study of women's experiences of participation in a diverse range of community groups, and considers how such involvement can potentially have a negative impact upon mental well-being. In-depth interviews were conducted with 30 women in Adelaide, South Australia. Women's accounts of their group involvement reflected that their identities as mothers were particularly important in shaping their participation. Some women reported difficulties in combining group involvement with their family responsibilities. Stress attached to negotiating social interaction within groups was also raised as an issue. It was found that participation can reinforce gender inequality and potentially have severe negative consequences for mental health, issues that need to be considered alongside the potential health benefits. The findings are considered in light of Bourdieu's critical conceptualization of social capital. Copyright © 2008 John Wiley & Sons, Ltd. [source] EFFECTS OF PROCESS VARIABLE CONDITIONS ON MINERAL AND CHEMICAL COMPOSITION OF EXTRUDED AFRICAN BREADFRUIT (TRECULIA AFRICANA DECNE) MIXTURESJOURNAL OF FOOD PROCESSING AND PRESERVATION, Issue 4 2009TITUS U. NWABUEZE ABSTRACT Five levels of African breadfruit (Treculia africana), corn and soybean mixtures (fc) in ratios of 40:5:55, 55:5:40, 70:5:25, 85:5:10 and 100:0:0, respectively, were hydrated to 15, 18, 21, 24 and 27% (fm) and extruded at 100, 120, 140, 160 and 180 rpm (ss) in a Brabender single-screw extruder. The objective was to study effects of process variable conditions on mineral and chemical composition of the mixtures. Models developed by response surface analysis were high (R2 = 0.7646,0.9732) for Na, Ca, Mg, protein, fat, fiber and carbohydrate, and showed no significant (P > 0.05) lack of fit. All process variables had significant (P , 0.05) linear effects on Mg, protein and carbohydrate, quadratic effects on fat, energy and Mg and cross-product effects on Ca, Mg, protein and carbohydrate, when fc interacted with either fm or ss. Optimum process variable conditions that gave the best mineral and chemical composition were obtained at 40:5:55(fc), 18% (fm) and 140 rpm (ss). PRACTICAL APPLICATIONS The potentials of African breadfruit as a nutrient resource and its position in the food cycle of the people in the subtropical African countries makes its blending with other local ingredients one important way of expanding the scope of its utilization. African breadfruit seeds provide a delicacy and a specialized meal when consumed alone or with shelled milk-corn. The versatility and acceptance of extrusion as a processing technology and its benefits over conventional methods and worldwide adaptability to a variety of crops, makes its application in this research appropriate. Optimization of process variable conditions affecting mineral and chemical composition of extruded and unextruded mixtures of African breadfruit, corn and soybean, using response surface analysis, was the thrust of the study. It is expected to produce an optimum process combination that could give the best mineral and chemical composition for a possible scale-up operation in African breadfruit seed processing enterprises. [source] Energy Efficiency and Structural Change in the Netherlands, 1980,1995JOURNAL OF INDUSTRIAL ECOLOGY, Issue 1 2000Dematerialization, Economic Structure on National Energy Consumption, Influence of Energy Efficiency Summary International agreement has been reached to reduce greenhouse gas emissions worldwide. One important way of decoupling CO2 emissions from economic growth is by introducing technical measures to improve energy efficiency. In this article, we assess the influence of developments in energy efficiency and economic structure on the total primary energy consumption in the Netherlands over the period 1980, 1995. We find a distinct decoupling of the economic growth and energy consumption of 1.5% per year in the 15-year analysis period. We measure (technical) changes in energy efficiency by changes in the energy consumption per physical unit of production or activity. The aggregate rate of (technical) energy-efficiency improvement was 1.4% per year over the period 1980,1995. The use of physical production indicators makes it possible to measure energy-efficiency developments without detailed surveys at a very low level of aggregation. When we look at economic structural changes over this period, we find that (i) no substantial shift took place at the level of the economic sectors that we distinguish; (ii) the most energy intensive subsectors grew much faster than the total economy; and (iii) at the subsector level, on average, a sizable decoupling of physical production and value added occurred. We conclude that structural changes, that is, changes in the composition of the economy, did not lead to a net decrease in the energy intensity of the Netherlands over the period 1980,1995. [source] "Revenue Accounting" in the Age of E-Commerce: A Framework for Conceptual, Analytical, and Exchange Rate ConsiderationsJOURNAL OF INTERNATIONAL FINANCIAL MANAGEMENT & ACCOUNTING, Issue 1 2002Jonathan C. Glover This paper explores "revenue accounting" in contrast to traditional "cost accounting". Revenue accounting serves the information needs of managers and investors in planning and controlling a firm's sales activities and their financial consequences, especially in the age of e-commerce. Weaknesses of traditional accounting have become particularly evident recently, for example, the lack of 1) revenue mileposts, 2) revenue sustainability measurements, and 3) intangibles capitalization. The paper emphasizes the need to develop a conceptual framework of revenue accounting and, as a tentative measure, proposes five basic postulates and five operational postulates of revenue accounting. On the side of analytical frameworks, the paper explores some tentative remedies for the weaknesses. Several revenue mileposts are explored to gauge progress in earning revenues and a Markov process is applied to an example involving mileposts. Revenue momentum, measured by the exponential smoothing method, is examined as a way of getting feedback on revenue sustainability; and the use of the sustainability concept in the analysis of "fixed and variable revenues" is illustrated. A project-oriented approach in a manner similar to capital budgeting and to Reserve Recognition Accounting is proposed by treating each customer as a project. Standardization of forecasts are also considered as an important way of bypassing the capitalization issue. Finally, while e-commerce is inherently global, issues specific to global operations are highlighted, namely, exchange rate issues when venture capitalists and the start-up company use different currencies producing different rates of return on the same project. [source] Group decisions in oncology: Doctors' perceptions of the legal responsibilities arising from multidisciplinary meetingsJOURNAL OF MEDICAL IMAGING AND RADIATION ONCOLOGY, Issue 3 2008MA Sidhom Summary There is growing consensus that multidisciplinary meetings (MDMs) are the optimal means of arriving at a comprehensive treatment plan for cancer patients. However, if a patient was grieved by a decision made by an MDM and wished to recover damages, the courts would find all involved consultants responsible for decisions related to their area of expertise. The aim of this study was to assess (i) whether doctors participating in oncology MDMs are aware that they are individually accountable for the MDM decisions and (ii) whether MDMs are conducted in a way that reflects this individual responsibility. A 35-question survey was developed and peer reviewed. Doctors attending MDMs in four Australian tertiary-care hospitals were invited to respond. One hundred and thirty-six responses (91% response rate) were received from 18 MDMs across 4 hospitals. Only 48% of doctors believe they are individually liable for decisions made by the MDM. This awareness was greater for an MDM where the patient attends, than in those that were ,discussion only' (58 vs 37%; P = 0.036). Seventy-three per cent stated they would like further education about their legal responsibilities in MDMs. Thirty-three per cent of doctors feel that the MDM discussion environment is suboptimal and radiation oncologists are significantly more likely to hold this view. Even though 85% of doctors have disagreed with the final MDM decision in an important way at some time, 71% did not formally dissent on those occasions. Doctors should be made aware of the legal implications of their participation in MDMs. A greater awareness of these responsibilities and improved team dynamics should optimize patient outcomes while limiting exposure of participants to legal liability. [source] Personal Goals in Social Roles: Divergences and Convergences Across Roles and Levels of AnalysisJOURNAL OF PERSONALITY, Issue 1 2000Kennon M. Sheldon Most contemporary personal goal research aggregates across goals, perhaps masking important differences between goals. We assessed this risk by examining both similarities and differences between the goals that participants pursued in five important social roles. Previous relevant findings (Cantor, Norem, Niedenthal, Langston, & Brower, 1987) and self-determination theory (Deci & Ryan, 1985) were used to predict between-role differences in goal appraisal dimensions. Although theoretically meaningful differences were found across child, employee, romantic, friendship, and student goals, and also across within- and between-subject levels of analysis, all goals were essentially the same in one important way: Making longitudinal progress in them predicted positive change in accompanying role-circumstances and role-satisfaction (excepting friendship goals). This indicates that researchers do not necessarily lose information by aggregating, and affirms that goal-attainment is generally desirable. [source] B7-H1 expression is upregulated in peripheral blood CD14+ monocytes of patients with chronic hepatitis B virus infection, which correlates with higher serum IL-10 levelsJOURNAL OF VIRAL HEPATITIS, Issue 11 2006L. Geng Summary., Chronicity in hepatitis B virus (HBV) infection is maintained by increased type 2 T-helper cell response, possibly because of increased interleukin-10 (IL-10) productions. B7-H1 can negatively regulate T-cell responses via its receptor, programmed death 1. Ligation of B7-H1 to T-cells can result in the preferential secretion of IL-10. In this study, we investigated whether there was an upregulated expression of B7-H1 in peripheral blood mononuclear cells in patients chronically infected by HBV and further explored the correlation between B7-H1 expression and serum interleukin 2, interferon- ,, IL-10, HBeAg, alanine aminotransferase (ALT) levels and viral load. Fifty-five patients with chronic HBV infection and 20 healthy controls (HCs) were enrolled in the present study. The results showed that in patients with chronic hepatitis B CD14+ monocytes but not CD3+ and CD19+ cells had a significantly increased expression of B7-H1 compared with HCs, which positively correlates with serum IL-10 levels and the presence of HBeAg and negatively correlates with serum ALT levels. In conclusion, chronic HBV patients harbour an increased B7-H1 expression in CD14+ monocytes compared with controls, which may be responsible for the increased serum IL-10 levels. This might be an important way by which HBV evades an adequate immune response, leading to viral persistence and disease chronicity. [source] Putting Concepts to Work: Some Thoughts for the Twentyfirst CenturyMIND & LANGUAGE, Issue 1 2004Jesse Prinz It allows for an inactive agent or pure reflector, and for agents whose actions in various ways seem to float free of their own conceptual repertoires. We show that naturally evolved creatures are not like that. In the real world, thinking is always and everywhere about doing. The point of having a brain is to guide the actions of embodied beings in a complex material world. Some of those actions are, to be sure, more recondite than others. But in every case the contents of thoughts still look to depend, in some non-unique but vitally important way, on the kinds of doings they support. [source] Validity of registry data: Agreement between cancer records in an end-stage kidney disease registry (voluntary reporting) and a cancer register (statutory reporting)NEPHROLOGY, Issue 4 2010ANGELA C WEBSTER ABSTRACT: Aims: End-stage kidney disease registries inform outcomes and policy. Data quality is crucial but difficult to measure objectively. We assessed agreement between incident cancer reported to the Australian and New Zealand Dialysis and Transplant Registry (ANZDATA) and to the Central Cancer Registry (CCR) in New South Wales. Methods: ANZDATA records were linked to CCR using probabilistic matching. We calculated agreement between registries for patients with ,1 cancers, all cancers and site-specific cancer using the kappa statistic (,). We investigated cases where records disagreed and compared estimates of cancer risk based either on ANZDATA or on CCR using standardized incidence ratios (indirect standardization by age, sex and calendar year). Results: From 1980 to 2001, 9453 residents had dialysis or transplantation. ANZDATA recorded 867 cancers in 779 (8.2%) registrants; CCR 867 cancers in 788 (8.3%). ANZDATA recorded 170 patients with cancer that CCR did not, CCR recorded 179 patients that ANZDATA did not (, = 0.76). ANZDATA had sensitivity 77.3% (confidence interval (CI) 74.2,80.2), specificity 98.1% (CI 97.7,98.3) if CCR records were regarded as the reference standard. Agreement was similar for diagnoses while receiving dialysis (, = 0.78) or after transplantation (, = 0.79), but varied by cancer type. Agreement was poorest for melanoma (, = 0.61) and myeloma (, = 0.47) and highest for lymphoma (, = 0.80), leukaemia (, = 0.86) and breast cancer (, = 0.85). Artefact accounted for 20.8% of the non-concordance but error and misclassification did occur in both registries. Estimates of cancer risk based on ANZDATA or CCR records did not differ in any important way. Conclusion: Agreement of cancer records between both registries was high and differences largely explicable. It is likely that both ANZDATA and CCR have some inaccuracies, for reasons that are now more explicit, with themes similar to those likely to be experienced by other registries. [source] Fate of abstracts presented at five International Conferences on Pharmacoepidemiology (ICPE): 1995,1999PHARMACOEPIDEMIOLOGY AND DRUG SAFETY, Issue 2 2002P. Stolk Abstract Background Meetings are an important way of exchanging scientific information, but full diffusion of new information can only be achieved when results are published in scientific journals. Purpose (1) To determine the publication frequency of accepted abstracts for the yearly international conferences on pharmacoepidemiology (ICPE) and to examine predicting variables; (2) if published, to determine impact differences between ,oral' and ,poster' abstracts and to determine type and nature of publishing journals. Results Overall, one out of three abstracts resulted in a publication in the peer-reviewed journals studied. Abstracts from North America were more often presented orally than abstracts from Europe, but had lower publication chances. ,Oral' abstracts were more likely to be published than ,poster' abstracts; abstracts with a strong methodological content had a lower publication frequency. Most of the published abstracts were found in pharmacology and pharmacy journals (33%) and journals on specific clinical topics (30%). Conclusions Only one out of three papers presented at ICPE ends up in established peer-reviewed journals. Although the publication characteristics for ICPE are not very different from other conferences, there are certain questions that warrant further investigation. Copyright © 2002 John Wiley & Sons, Ltd. [source] Soft magnetic properties and microstructure of Fe65Co35 thin films with different underlayersPHYSICA STATUS SOLIDI (A) APPLICATIONS AND MATERIALS SCIENCE, Issue 5 2006Yu Fu Abstract High-moment soft magnetic Fe65Co35 thin films with well in-plane uniaxial anisotropy were obtained by cosputtering on Co93Fe7, Ni80Fe20, Cu and Fe underlayers. The single-layer Fe65Co35 film with thickness of 100 nm shows a magnetic anisotropy. The coercivity along easy axis Hce and that along hard axis Hch are equal to 3.3 kA/m and 2.1 kA/m, respectively. The soft magnetic properties of Fe65Co35 films were much improved by using an underlayer. The Hce and Hch of Fe65Co35 films with Ni80Fe20, Co93Fe7 and Cu underlayers can be reduced to 0.9,1.1 kA/m and 0.08,0.20 kA/m, respectively. For films with Fe underlayer, the Hce and Hch reduced to 1.1 kA/m and 0.6 kA/m, respectively. In the case of Co93Fe7, Ni80Fe20 and Fe underlayers, the coercivity of films did not depend remarkably on the thickness t of underlayer at t > 1 nm. While in the case of Cu underlayer, the coercivity of films changed remarkably with increasing underlayer thickness. It was shown that the texture of double-layered underlayer/Fe65Co35 films is dependent on the material and the thickness of underlayer. The influence of the underlayer on the surface morphology and micro-magnetic structure of films were investigated by AFM and MFM. It was suggested that the modification of the structure of Fe65Co35 films by using an underlayer is an important way to improve their soft magnetic properties. (© 2006 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim) [source] DOES PART-TIME EMPLOYMENT PROVIDE A WAY OF ACCOMMODATING A DISABILITY?,THE MANCHESTER SCHOOL, Issue 6 2007MELANIE K. JONES In this paper, I examine the reasons for high rates of part-time employment among disabled workers in the UK. Evidence from the Labour Force Survey suggests that part-time employment provides an important way of accommodating a work-limiting disability rather than reflecting marginalization of the disabled by employers. Differences in part-time employment within the disabled group are also examined. [source] Ultrastructural Evidence for a Novel Accumulation of Ca in a Microbial Mat from a Slight Acidic Hot SpringACTA GEOLOGICA SINICA (ENGLISH EDITION), Issue 3 2010Xiaotong PENG Abstract: Microbial mats are ecosystems that can control or induce the precipitation of calcium (Ca) carbonate on Earth through geological time. In the present study, we report on a novel accumulation of Ca, together with iron (Fe), in a microbial mat collected from a slight acidic hot spring (pH=5.9) in south China. Combining an array of approaches, including environmental scanning electron microscopy, X-ray microanalysis, transmission electron microscopy, and selected area electron diffraction, we provide ultrastructral evidence for amorphous acicular aggregates containing Ca and Fe associated with cyanobacteria precipitating in the microbial mats. Cyanobacterial photosynthesis and exopolymeric organic matrixes are considered to be responsible for the precipitation of Ca. These amorphous acicular aggregates might imply the early stage of calcification occurring in microbial mats. Ca and Fe coprecipitation indicates another potential important way of inorganic element precipitation in hot spring microbial mats. Our results provide insight into the possible mechanism of cyanobacterial calcification and microfossil preservation in slight acidic hot spring environments. [source] Effectiveness of an oral health education programme in primary schools in Zimbabwe after 3.5 yearsCOMMUNITY DENTISTRY AND ORAL EPIDEMIOLOGY, Issue 4 2001Jo E. Frencken Abstract , Many medical and dental professionals in African nations believe that school teachers, through attendance of a short workshop, can be trained to provide oral health education. This increases the number of professionals available and is regarded as an important way forward in improving oral health. Objectives: The current study assesses the effectiveness of an oral health education programme administered by schoolteachers in a district in Zimbabwe over a period of 3.5 years. Methods: The experimental group consisted of schools that had sent representatives to a regional workshop on oral health held in 1992. The control group was selected at random from schools not having attended the workshop. A total number of 439 boys and 526 girls were examined in 1992. Follow-up evaluations were carried out in 1993, 1994 and 1996. The dependent variables were plaque accumulation and caries increment in grade 2 and grade 4 children of experimental and control schools. Results: ANOVA test with year of evaluation (1992,94), experiment/control school, age and gender as independent variables showed no statistically significant difference in mean plaque scores in longitudinally examined original grade 2 (P>0.20) and grade 4 children (P=0.06) from experimental and control schools. The mean caries increment score in the experimental and control schools was 0.04 and 0.19, respectively. ANOVA test with fluoride levels and gender as independent variables on caries increment in experimental and control schools did not show a statistically significant difference (P=0.06). Conclusion: The one-time training of teachers in aspects of oral health was ineffective in lowering plaque levels over a period of 3.5 years. Considering the low caries increment observed over the study period, the effect of the oral health programme on caries levels in the study group was inconclusive. [source] Changes over time in homicides by women: a register-based study comparing female offenders from 1982 to 1992 and 1993 to 2005CRIMINAL BEHAVIOUR AND MENTAL HEALTH, Issue 5 2008Hanna Putkonen Background,The contribution of women to violent offending, including homicide, may be increasing as society changes. Aims,The aim of this paper was to test for trends in homicide by women in Finland. Methods,A retrospective register-based study was conducted by comparing two national cohorts: one from 1982 to 1992 and the other from 1993 to 2005. Results,There was a small increase in the proportion of homicides committed by women over time, but the most striking difference between the cohorts was in the significantly higher frequency of alcohol abuse/dependence in the later cohort and of being under the influence of alcohol during the crime. Fewer perpetrators were regarded as lacking or being of diminished responsibility in the later cohort. The victims of the earlier cohort were emotionally closer to the offender than those of the later one. Conclusions,In Finland, there have been changes in characteristics of women who commit homicide and their crimes over time, with the apparent development of a subgroup of women who kill who are much more like men who kill than women in the 1980s and early 1990s. Preventing substance abuse and marginalization are likely to be important ways of preventing homicide by both female and male perpetrators. Copyright © 2008 John Wiley & Sons, Ltd. [source] ON THE RELATIONSHIP BETWEEN FAMILY STRUCTURE AND ANTISOCIAL BEHAVIOR: PARENTAL COHABITATION AND BLENDED HOUSEHOLDS,CRIMINOLOGY, Issue 1 2008ROBERT APEL In the last several decades, the American family has undergone considerable change, with less than half of all adolescents residing with two married biological parents. Using the National Longitudinal Survey of Youth 1997, we construct an elaborate measure of family structure and find considerable heterogeneity in the risk of antisocial and delinquent behavior among groups of youth who reside in what are traditionally dichotomized as intact and nonintact families. In particular, we find that youth in "intact" families differ in important ways depending on whether the two biological parents are married or cohabiting and on whether they have children from a previous relationship. In addition, we find that youth who reside with a single biological parent who cohabits with a nonbiological partner exhibit an unusually high rate of antisocial behavior, especially if the custodial parent is the biological father. [source] THE MULTILEVEL CONTEXT OF CRIMINAL SENTENCING: INTEGRATING JUDGE- AND COUNTY-LEVEL INFLUENCES,CRIMINOLOGY, Issue 2 2006BRIAN D. JOHNSON This study extends recent inquiries of contextual effects in sentencing by jointly examining the influence of judge and courtroom social contexts. It combines two recent years of individual sentencing data from the Pennsylvania Commission on Sentencing (PCS) with data on judicial background characteristics and county court social contexts. Three-level hierarchical models are estimated to investigate the influence of judge and county contexts on individual variations in sentencing. Results indicate that nontrivial sentencing variations are associated with both individual judge characteristics and county court contexts. Judicial background factors also condition the influence of individual offender characteristics in important ways. These and other findings are discussed in relation to contemporary theoretical perspectives on courtroom decision making that highlight the importance of both judge and court contexts in sentencing. The study concludes with suggestions for future research on contextual disparities in criminal sentencing. [source] DEFINING STANDARD OF CARE IN THE DEVELOPING WORLD: THE INTERSECTION OF INTERNATIONAL RESEARCH ETHICS AND HEALTH SYSTEMS ANALYSISDEVELOPING WORLD BIOETHICS, Issue 2 2005ADNAN A. HYDER ABSTRACT In recent years there has been intense debate regarding the level of medical care provided to ,standard care' control groups in clinical trials in developing countries, particularly when the research sponsors come from wealthier countries. The debate revolves around the issue of how to define a standard of medical care in a country in which many people are not receiving the best methods of medical care available in other settings. In this paper, we argue that additional dimensions of the standard of care have been hitherto neglected, namely, the structure and efficiency of the national health system. The health system affects locally available medical care in two important ways: first, the system may be structured to provide different levels of care at different sites with referral mechanisms to direct patients to the appropriate level of care. Second, inefficiencies in this system may influence what care is available in a particular locale. As a result of these two factors locally available care cannot be equated with a national ,standard'. A reasonable approach is to define the national standard of care as the level of care that ought to be delivered under conditions of appropriate and efficient referral in a national system. This standard is the minimum level of care that ought to be provided to a control group. There may be additional moral arguments for higher levels of care in some circumstances. This health system analysis may be helpful to researchers and ethics committees in designing and reviewing research involving standard care control groups in developing country research. [source] The effects of seizures on the connectivity and circuitry of the developing brainDEVELOPMENTAL DISABILITIES RESEARCH REVIEW, Issue 2 2004John W. Swann Abstract Recurring seizures in infants and children are often associated with cognitive deficits, but the reason for the learning difficulties is unclear. Recent studies in several animal models suggest that seizures themselves may contribute in important ways to these deficits. Other studies in animals have shown that recurring seizures result in dendritic spine loss. This change, coupled with a down-regulation in NMDA receptor subunit expression, suggests that repetitive seizures may interrupt the normal development of glutamatergic synaptic transmission. We hypothesize that homeostatic, neuroprotective processes are induced by recurring early-life seizures. These processes, by diminishing glutamatergic synaptic transmission, are aimed at preventing the continuation of seizures. However, by preventing the normal development of glutamatergic synapses, and particularly NMDA receptor-mediated synaptic transmission, such homeostatic processes also reduce synaptic plasticity and diminish the ability of neuronal circuits to learn and store memories. MRDD Research Reviews 2004;10:96,100. © 2004 Wiley-Liss, Inc. [source] Patterns of motor disability in very preterm childrenDEVELOPMENTAL DISABILITIES RESEARCH REVIEW, Issue 4 2002Melanie Bracewell Abstract Motor development in very preterm children differs in several important ways from that of children born at full term. Variability is common, although the anatomic and physiologic bases for that variability are often poorly understood. Motor patterns over the first postnatal year may depend on behaviours learned during often long periods of neonatal intensive care. The normal pattern of development may be modified by disturbances of brain function caused both by the interruption of normal brain maturation ex-utero and the superimposition of focal brain injuries following very preterm birth. Abnormal patterns of development over the first year may evolve into clear neuromotor patterns of cerebral palsy or resolve, as "transient dystonias." Cerebral palsy is associated with identified patterns of brain injury secondary to ischaemic or haemorrhagic lesions, perhaps modified by activation of inflammatory cytokines. Cerebral palsy rates have not fallen as might be expected over the past 10 years as survival has improved, perhaps because of increasing survival at low gestations, which is associated with the highest prevalence of cerebral palsy. Children who escape cerebral palsy are also at risk of motor impairments during the school years. The relationship of these impairments to perinatal factors or to neurological progress over the first postnatal year is debated. Neuromotor abnormalities are the most frequent of the "hidden disabilities" among ex-preterm children and are thus frequently associated with poorer cognitive ability and attention deficit disorders. Interventions to prevent cerebral palsy or to reduce these late disabilities in very preterm children are needed. MRDD Research Reviews 2002;8:241,248. © 2002 Wiley-Liss, Inc. [source] | ||||||||||||||||||||||||||||||||||||||||||||||