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Important Public Health Issue (important + public_health_issue)
Selected AbstractsMutations in the factor IX gene (F9) during the past 150 years have relative rates similar to ancient mutationsHUMAN MUTATION, Issue 1 2002Jinong Feng Abstract Pollutants and dietary mutagens have been associated with somatic mutation and cancer, but the extent of their influence on germline mutation is not clear. Since deleterious germline mutations can be transmitted for thousands of years, any influence on germline mutation from the vast increase in man-made chemicals of the past 150 years would be an important public health issue. Observed disease causing mutations in the X-linked factor IX gene (F9) of hemophilia B patients originated predominantly in the past 150 years, since the half-life of these mutations in human populations had been about two generations before effective treatment became available about a generation ago. Recent changes in germline mutational processes may be detected by comparison of the observed hemophilia B causing mutation pattern in F9 with the pattern of neutral polymorphisms which occurred over a much longer period of time. By scanning a total of 1.5 megabases of deep intronic regions of F9 in the genomic DNA from 84 individuals, 42 neutral polymorphisms were found in 23 haplotypes that differed by at least 11 mutations from the ancestral primate haplotype. By sequencing F9 in seven non-human primates, 39 of these polymorphisms were characterized as ancient mutations relative to a unanimous ancestral primate allele. This ancient mutation pattern was compared to the recent pattern of hemophilia B causing mutations. Remarkably, no significant difference was found (P=0.5), suggesting that the vast increase in man-made chemicals during the past 150 years has not had a major impact on the pattern of human germline mutation. This result is consistent with the hypothesis that endogenous processes dominate germline mutation. Hum Mutat 19:49,57, 2002. © 2001 Wiley-Liss, Inc. [source] Content analysis of food advertising in Turkish televisionJOURNAL OF PAEDIATRICS AND CHILD HEALTH, Issue 7-8 2010Tulay Guran Aim: Television (TV) viewing has been implicated in children's weight gain. We aimed to conduct a comprehensive content analysis of TV food advertising in Turkey. Methods: TV advertisements (ads) in the four most popular national free to air Turkish TV channels, were assessed on two weekdays and two weekend days at four time periods of the day; 0800,1200,1200,1600,1600,2000 and 2000,2400 h for each TV channel (64 h assessed for each TV channel), making a total of 256 h. Each ad was analysed for food and drink content, duration and audiovisual properties. Results: There were 8853 TV ads and 2848 of these were related to food (32.1%). A majority of food ads included high-calorie, high-fat, high-sugar food and drink rather than core/healthy foods (81%). Chocolate and chocolate bars were the most frequently advertised food/drink product, followed by cakes, coffee, tea, candies, gum, fast food, chips, juices/carbonated beverages, margarine and ice-cream formed the highest rate of food products advertised in decreasing order. Thirty per cent of all obesogenic/unhealthy ads targeted childhood by using audiovisual techniques. The proportion of total advertisements which were for food or drink, and the proportion of food advertisements that were for unhealthy foods were both much higher at the weekend (33% vs. 30% and 84% vs. 78%, respectively). The time period between 1600 and 2000 h was the most concentrated time slot (33%) for food advertising. Conclusions: This study provides data for the first time on the high levels of obesogenic food advertising on Turkish TV. This should alarm policy-makers to set limits on food advertising targeted towards children especially in countries like Turkey in which childhood obesity is emerging as an important public health issue. [source] Adolescent Behavioral, Affective, and Cognitive Engagement in School: Relationship to DropoutJOURNAL OF SCHOOL HEALTH, Issue 9 2009Isabelle Archambault PhD ABSTRACT BACKGROUND: High school dropout represents an important public health issue. This study assessed the 3 distinct dimensions of student engagement in high school and examined the relationships between the nature and course of such experiences and later dropout. METHODS: We administered questionnaires to 13,330 students (44.7% boys) from 69 high schools in the province of Quebec (Canada). During 3 consecutive high school years, students reported their behavioral, emotional, and cognitive engagement to school. Information on later dropout status was obtained through official records. RESULTS: Although many adolescents remained highly engaged in high school, one third reported changes, especially decreases in rule compliance, interest in school, and willingness to learn. Students reporting low engagement or important decrements in behavioral investment from the beginning of high school presented higher risks of later dropout. CONCLUSION: School-based interventions should address the multiple facets of high school experiences to help adolescents successfully complete their basic schooling. Creating a positive social-emotional learning environment promises better adolescent achievement and, in turn, will contribute to a healthier lifestyle. [source] Dermatophytoses in outpatients attending the Dermatology Center of Avicenna Hospital in Qazvin, IranMYCOSES, Issue 2 2008Mohammad Reza Aghamirian Summary Dermatophytosis is still being considered as one of the major public health problems in many parts of the world. To identify the prevalence and etiological agents of dermatophytoses, a study was carried out between 2004 and 2006. Out of 1023 subjects suspected to have cutaneous mycoses, 348 (34%) patients were affected with dermatophytoses. The causative agents were identified macroscopically and microscopically after the clinical samples were subjected to potassium hydroxide examination and culture isolation. Epidermophyton floccosum was the most frequently isolated species representing 32.8% of isolates, followed by T. rubrum (18.1%), T. verrucosum (17.2%), T. mentagrophytes var. interdigitale (15.8%), T. mentagrophytes var. mentagrophytes (6.6%) and T. violaceum, T. schoenleinii and Microsporum canis (0.9%). The most common type of infection was tinea cruris (31.9%) affecting in particular male patients. Some other most prevalent tinea types were tinea corporis (20.7%), tinea pedis (19%), and tinea unguium (11.2%). To the best of our knowledge, this is the first report on dermatophytoses in Qazvin and the first study that shows tinea cruris as a major type of superficial fungal infection in Iran. The frequency of tinea was higher in males and tinea cruris showed a remarkably increasing tendency and was an important public health issue in Qazvin. [source] Nonfatal unintentional injuries and related factors among male construction workers in central ChinaAMERICAN JOURNAL OF INDUSTRIAL MEDICINE, Issue 6 2010Lei Zheng Abstract Background Work-related injuries (WRIs) among construction workers have recently emerged as an important public health issue as the construction industry is booming in China. We investigated nonfatal unintentional work-related injuries and risk factors among male construction workers in central China. Methods A purposive sampling method was used in 2008 to select 1,260 male workers from 24 construction sites. WRIs that occurred in the past 12 months and possible risk factors were asked about in face-to-face interviews. Results Among 1,260 male construction workers, 189 workers reported WRIs. The annual prevalence of nonfatal WRIs was 15.0 per 100 workers (95% confidence interval (CI): 13.0,17.0). The top three leading causes of injuries were collisions (27.3 per 100 workers), cuts/piercings (17.5 per 100 workers), and falls (15.5 per 100 workers). WRIs were significantly associated with high cigarette pack-year index (PYI,,,20 vs. nonsmoker: adjusted odds ratio (OR),=,2.50, 95% CI: 1.31,4.76), serious alcohol consumption (,30ml/day vs. nondrinker: adjusted OR,=,1.73, 95 %CI: 1.12,2.69), not having injury prevention and safety education (adjusted OR,=,2.05, 95% CI: 1.22,3.44), and had depressive symptoms (adjusted OR,=,2.63, 95% CI: 1.22,5.67). Conclusions Our results suggest that annual prevalence of nonfatal construction injuries is high in central China and serious cigarette smoking, serious alcohol consumption, not having injury prevention and safety education, and depressive symptoms are considered important factors for those injuries. Am. J. Ind. Med. 53: 588,595, 2010. © 2010 Wiley-Liss, Inc. [source] Using surveillance data to promote occupational health and safety policies and practice at the state level: A case study,,AMERICAN JOURNAL OF INDUSTRIAL MEDICINE, Issue 2 2010Geoffrey M. Calvert MD Abstract Background Following the investigation of a birth defects cluster involving migrant farmworkers employed in North Carolina and Florida, it became clear that greater efforts were needed to protect agricultural workers from pesticide exposure. Methods Documentation is drawn from peer-reviewed published articles, government reports and news accounts. Results The birth defects cluster was identified and investigated by state and federal pesticide poisoning surveillance system staff. Following the investigation, efforts were initiated to highlight pesticides as an important public health issue needing more attention. A series of subsequent events led to the creation and passage of important legislation recently enacted in North Carolina. The legislation resulted in funding to promote various activities to prevent harm from pesticides including strengthening surveillance, improving the quality of pesticide compliance inspections, and increasing and improving pesticide safety training. The legislation also broadened the coverage of anti-retaliation rules to include agricultural workers, and increased recordkeeping requirements pertaining to pesticide applications. Conclusion The important and positive impacts that can occur through surveillance activities are highlighted. As such, it is important to continue to support and improve occupational illness and injury surveillance programs. Am. J. Ind. Med. 53:188,193 2010. Published 2009 Wiley-Liss, Inc. [source] Waterpipe tobacco smoking: an important public health issueAUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH, Issue 5 2008Therese Carroll No abstract is available for this article. [source] | ||||||||||