			Home About us Contact

IM Group (im + group)

Distribution by Scientific Domains

Medical Sciences	75%

Selected Abstracts

Failure Modes with Point Loading of Three Commercially Available Denture Teeth

JOURNAL OF PROSTHODONTICS, Issue 6 2008
Andrew R. Moffitt DDS
Abstract Purpose: A common problem associated with implant-supported prostheses is the fracture of denture teeth. This study was designed to compare the fracture modes of three denture teeth by compressive load at a 30° off-axis angle. Material and Methods: Three denture teeth (Vident Duostat, Ivoclar Vivadent, and Dentsply Trubyte) processed to two denture base processing systems [injection-molded (IM) SR-Ivocap system and compression-molded (CM) denture base resin] were evaluated. Each specimen was processed to a metal framework. Ultimate failure strength of each system when point loaded at a 30° off-axis angle was recorded, along with a visual inspection of each specimen. Results: The average load fracture for each group was (in N): Vident CM 1106.97 ± 223.20, Vident IM 1168.18 ± 322.52, Dentsply CM 1098.08 ± 286.32, Dentsply IM 1023.80 ± 282.45, Ivoclar CM 1616.98 ± 204.87, and Ivoclar IM 1373.54 ± 282.58. There was a significant difference between the groups and the Ivoclar CM group. The Ivoclar CM group had the highest average load force, and the Dentsply IM group had the lowest average load force. On average, the teeth within the groups fractured at a higher compression force than the average maximum occlusal force in natural dentition. Dentsply and Vident denture teeth fractured more horizontally, and the Ivoclar denture teeth fractured more vertically within the groups. There was no significant difference among the groups between the IM and CM processing methods. Conclusions: In the present in vitro study, all specimens were able to withstand 30° off-axis loading with the exception of one specimen. With these results, this would indicate that these denture teeth are able to withstand normal occlusal forces. [source]

Immunogenicity of an inactivated adjuvanted whole-virion influenza A (H5N1, NIBRG-14) vaccine administered by intramuscular or subcutaneous injection

MICROBIOLOGY AND IMMUNOLOGY, Issue 2 2010
Daisuke Ikeno
ABSTRACT The immunogenicity and safety profile of an inactivated whole-virion influenza A (H5N1, NIBRG-14) vaccine with alum adjuvant that was administered by IM or SC injection in a phase I clinical study involving 120 healthy Japanese men aged 20,40 years is described. The serological response of the IM group was stronger than that of the SC group. Local adverse events were less severe with IM injection than with SC injection, while similar systemic adverse events were seen in both groups. These results indicate that, when administering an inactivated whole virion vaccine with alum adjuvant for pandemic influenza, IM injection may achieve better immunogenicity and safety than SC injection. [source]

Pediatric Procedural Sedation with Ketamine: Time to Discharge after Intramuscular versus Intravenous Administration

ACADEMIC EMERGENCY MEDICINE, Issue 2 2009
Preeti Ramaswamy MBBS
Abstract Objectives:, Ketamine is an attractive agent for pediatric procedural sedation. There are limited data on time to discharge comparing intramuscular (IM) vs. intravenous (IV) ketamine. The authors set out to determine whether IM or IV ketamine leads to quicker discharge from the emergency department (ED) and how side effect profiles compare. Methods:, All patients who had received ketamine IM or IV at a tertiary children's hospital ED during the 3-year study period (2004,2007) were identified. Prospective sedation registry data, retrospective medical records, and administrative data were reviewed for drug dosages, use of additional agents, time of drug administration to discharge, total ED time (triage to discharge), and adverse events. A subgroup analysis for patients requiring five or fewer sutures (short suture group) was performed. Results:, A total of 229 patients were enrolled (60% male) with median age of 2.8 years (IQR =1.8,4.3 years) and median weight of 15.7 kg (range = 8.7,74 kg). Ketamine was most frequently employed for laceration repair (80%) and foreign body removal (9%). Overall, 48% received ketamine IM and 52% received it IV. In the short-suture subgroup, 52% received ketamine IM, while 48% received it IV. Multivariate linear regression analysis determined time from drug administration to patient discharge as 21 minutes shorter for IV compared with IM administration, adjusted for age and number of additional doses (R2 = ,0.35; 95% CI = ,0.5 to ,0.19; p < 0.001). Total time in the ED (triage to discharge) comparing IV versus IM administration, adjusting for age and gender and number of additional doses, was not significantly different (p = 0.16). In the short-suture subgroup, time to discharge from administration was also shorter in the IV ketamine group (R2 = ,0.454; 95%CI = ,0.66 to ,0.25; p < 0.001) but similar for total time in ED (p = 0.16). Overall, adverse events occurred in 35% (95% CI = 27% to 45%) of the IM group and 20% (95% CI = 13% to 28%) of the IV group (p = 0.01). Only one patient required brief bag-mask ventilation. Conclusions:, In this institution, time from drug injection to discharge was shorter in the IV compared to IM ketamine group, both overall and for the short-suture group. However, time from triage to discharge was similar. [source]

Intramuscular hepatitis B immunoglobulin (HBIG) and nucleosides for prevention of recurrent hepatitis B following liver transplantation: comparison with other HBIG regimens

CLINICAL TRANSPLANTATION, Issue 4 2007
Robert D Anderson
Abstract:, High titer hepatitis B immunoglobulin (HBIG) has significantly reduced the recurrence of hepatitis B virus (HBV) infection after liver transplantation. We compared our experience with intramuscular (IM) HBIG prophylaxis to our earlier outcomes with intravenous (IV) HBIG and other regimens. Methods:, One hundred and twenty-three patients with acute or chronic hepatitis B underwent liver transplant at the Baylor Regional Transplant Center between July 1985 and July of 2005. Of these, 63 (43%) received long-term low-dose IM (n = 17) or high-dose IV (n = 46) HBIG. All patients in IM group also received a nucleoside before and after transplant. These patients were compared with those transplanted earlier who received either no prophylaxis (n = 16) or HBIG on day zero and one only (n = 44). Results:, HBV recurrence was significantly lower in patients who received long-term HBIG [9/38 (23.7%) for IV and 1/17 (5.9%) for IM] compared with patients who received no treatment (8/11; 72.7%) or only two doses of HBIG (32/40; 80.0%). Two-yr actuarial survivals were 89%, 88%, 54%, and 64%, respectively. Patients on long-term HBIG by either parenteral route survived as well as patients transplanted for other indications. Post-transplant recurrence of hepatitis B in the long-term HBIG groups was usually controlled by intensifying antiviral therapy. Conclusion:, Long-term low-dose IM and high-dose IV HBIG are equally efficacious with similar survival and early hepatitis recurrence rates. Graft loss is usually avoidable when recurrence is discovered early and aggressively treated. The IM route is preferable to IV administration due to its ease of administration and lower cost. [source]