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Hybrid Microfluidic Chip (hybrid + microfluidic_chip)

Distribution by Scientific Domains
Chemistry50%

Kinds of Hybrid Microfluidic Chip

  • glass hybrid microfluidic chip
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    Selected Abstracts

    Electrochemical Detection of Anions on an Electrophoresis Microchip with Integrated Silver Electrode

    ELECTROANALYSIS, Issue 13 2005
    Jilin Yan
    Abstract A poly(dimethylsiloxane)/glass hybrid microfluidic chip with integrated silver electrode is described for electrochemical detection of anions. The working electrode was directly fabricated on a glass slide and the chip formed by reversibly sealing of a PDMS slab with microchannels to the slide. Under an alkaline phosphate condition, thiocyanide and three halides were sensitively detected. Factors influencing the separation and detection procedure were discussed and optimized. Linear responses over two magnitudes were obtained with limit of detection at the micromolar level. [source]

    Temperature gradient focusing in a PDMS/glass hybrid microfluidic chip

    ELECTROPHORESIS, Issue 24 2007
    Takuya Matsui
    Abstract This paper reports the application of temperature gradient focusing (TGF) in a PDMS/glass hybrid microfluidic chip. With TGF, by the combination of a temperature gradient along a microchannel, an applied electric field, and a buffer with a temperature-dependent ionic strength, analytes are focused by balancing their electrophoretic velocities against the bulk velocity of the buffer containing the analytes. In this work, Oregon Green 488 carboxylic acid was concentrated approximately 30 times as high as the initial concentration in 45,s at moderate electric strength of 70,V/cm and a temperature gradient of 55°C across the PDMS/glass hybrid microfluidic chip with a 1,cm long capillary. [source]

    Quantification of D -Asp and D -Glu in rat brain and human cerebrospinal fluid by microchip electrophoresis

    JOURNAL OF SEPARATION SCIENCE, JSS, Issue 17 2009
    Yong Huang
    Abstract A microchip electrophoresis (MCE) method with LIF detection was presented for quantification of D -aspartic acid (D -Asp) and D -glutamate (D -Glu) in biological samples. D -Asp and D -Glu were determined after precolumn derivatization with FITC. The chiral separation was performed on a glass/PDMS hybrid microfluidic chip using ,-CD as chiral selector in the running buffer. High sensitive detection was obtained by the LIF detection. The LODs (S/N = 3) for D -Asp and D -Glu were 6.0×10,8 and 4.0×10,8 M, respectively. Using this method, the levels of D -Asp and D -Glu in rat brain and human cerebrospinal fluid (CSF) were determined. [source]