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Human Neonates (human + neonate)

Distribution by Scientific Domains

Psychology	60%
Medical Sciences	40%

Selected Abstracts

Listening to language at birth: evidence for a bias for speech in neonates

DEVELOPMENTAL SCIENCE, Issue 2 2007
Athena Vouloumanos
The nature and origin of the human capacity for acquiring language is not yet fully understood. Here we uncover early roots of this capacity by demonstrating that humans are born with a preference for listening to speech. Human neonates adjusted their high amplitude sucking to preferentially listen to speech, compared with complex non-speech analogues that controlled for critical spectral and temporal parameters of speech. These results support the hypothesis that human infants begin language acquisition with a bias for listening to speech. The implications of these results for language and communication development are discussed. [source]

The ,oestrogen hypothesis', where do we stand now?,

INTERNATIONAL JOURNAL OF ANDROLOGY, Issue 1 2003
Richard M. Sharpe
Summary The original ,oestrogen hypothesis' postulated that the apparent increase in human male reproductive developmental disorders (testis cancer, cryptorchidism, hypospadias, low sperm counts) might have occurred because of increased oestrogen exposure of the human foetus/neonate; five potential routes of exposure were considered. This review revisits this hypothesis in the light of the data to have emerged since 1993. It addresses whether there is a secular increasing trend in the listed disorders and highlights the limitations of available data and how these are being addressed. It considers whether new data has emerged to support the suggestion that increased oestrogen exposure could cause these abnormalities and reviews new data on potential routes via which such increased exposure could have occurred. Secular trends: The disorders listed above are now considered to represent a syndrome of disorders (testicular dysgenesis syndrome, TDS) with a common origin in foetal life. Testicular cancer has increased in incidence in Caucasian men worldwide and lifetime risk is 0.3,0.8%. Secular trends in cryptorchidism are unclear but it is by far the commonest (2,4% at birth) congenital abnormality in either sex. Secular trends for hypospadias are not robust, although most studies suggest a progressive increase; registry data probably under-estimates incidence, but based on this data hypospadias is the second most common (0.3,0.7% at birth) congenital malformation. Retrospective analyses of sperm count data show a global downward trend but this is inconclusive , prospective studies using standardized methodology show significant differences between countries and very low sperm counts in the youngest cohort of men. For all disorders, other then testis cancer, standardized prospective studies are the best way forward and are in progress across Europe. Oestrogen effects: Evidence that foetal exposure to oestrogens can induce the above disorders has strengthened. New pathways via which such changes could be induced have been identified, including suppression of testosterone production by the foetal testis, suppression of androgen receptor expression and suppression of insulin-like factor-3 (InsL3) production by foetal Leydig cells. Other evidence suggests that the balance between androgen and oestrogen action may be important in induction of reproductive tract abnormalities. Oestrogen exposure: Although many new environmental oestrogens have been identified, their uniformly weak oestrogenicity excludes the possibility that they could induce the above disorders. However, emerging data implicates various environmental chemicals in being able to alter endogenous levels of androgens (certain phthalates) and oestrogens (polychlorinated biphenyls, polyhalogenated hydrocarbons), and the former have been shown to induce a similar collection of disorders to TDS. Other mechanisms via which increased fetal exposure to pregnancy oestrogens might occur (increasing trend in obesity, dietary changes) are also discussed. [source]

Primal seduction, matricial space and asymmetry in the psychoanalytic encounter

THE INTERNATIONAL JOURNAL OF PSYCHOANALYSIS, Issue 4 2004
Viviane Chetrit-Vatine
Wishing to highlight the asymmetric dimension that characterizes ethics as ,responsibility toward the other' in Levinas's philosophy, the author presents as an introduction three related concepts of Levinas's thinking: the caress, the face, the saying. Following some poetic narrative reflections offered as ,interlude' moments, the author seeks to bring together her concept of ,matricial space' inspired by Levinas's conception of ethics and the Laplanchian concept of ,primal seduction', both based on asymmetry. She suggests adding to Laplanche's proposition of two kinds of transference (filled-in transference and hollowed-out transference) a third kind: the matricial-space transference. She argues that together with the hollowed-out transference, which is related to the primal seduction, the matricial-space transference, which relates to the matricial position in the parent/analyst, is provoked by the analyst. If the hollowed-out transference assures the moving-on of the analysis, the matricial-space transference, in combination with the hollowed-out transference, is prerequisite for transformation to occur and may be deciphered specifically in ,impasse' situations, at what she coined ,subjectal moments'. As a conclusion, while insisting on the need for asymmetry in the analytic encounter, she suggests the existence in the human neonate of a need for ethics, and she questions the origin of the human capacity to be responsible toward the other. She illustrates her argument using clinical material from her own work alongside that of other authors. [source]

From imitation to conversation: the first dialogues with human neonates

INFANT AND CHILD DEVELOPMENT, Issue 3 2006
Emese Nagy
Abstract The functional maturity of the newborn infant's brain, the resemblances between neonatal imitation and imitation in adults and the possibly lateralized neonatal imitation suggest that the mirror neuron system may contribute to neonatal imitation. Newborn infants not only imitate but also initiate previously imitated gestures, and are able to participate in overlapping imitation,initiation communicative cycles. Additionally, these social responses in neonates are faster than previously thought, and may enable them to have long-lasting intimate interactions much before language develops. Infants are equipped with a powerful, innate, reciprocal communicative ability already at birth. The earliest communication originates from imitation and this communicative ability presumably later evolves to language. Copyright © 2006 John Wiley & Sons, Ltd. [source]

Parenteral Nutrition,associated Cholestasis in Neonates: The Role of Aluminum

NUTRITION REVIEWS, Issue 9 2003
Chris J. Arnold RD
Parenteral nutrition (PN) is an essential component in the care of premature and ill infants. The incidence of parenteral nutrition,associated cholestasis (PNAC) ranges from 7.4 to 84%. One substance in PN solutions that has been implicated in PNAC is aluminum. Aluminum loading in animals and humans causes hepatic accumulation and damage. The degree of aluminum contamination of PN solutions has decreased over time, but contamination still significantly exceeds levels that are safe for human neonates. Further study into the relationship between aluminum contamination in neonatal PN solutions and the development of PNAC is necessary. [source]