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Hormone Measurement (hormone + measurement)

Distribution by Scientific Domains
Medical Sciences100%

Selected Abstracts

Letter 1: Focused parathyroid surgery with intraoperative parathyroid hormone measurement as a day-case procedure (Br J Surg 2004; 91: 78,82)

BRITISH JOURNAL OF SURGERY (NOW INCLUDES EUROPEAN JOURNAL OF SURGERY), Issue 7 2004
G. Materazzi
No abstract is available for this article. [source]

Letter 2: Focused parathyroid surgery with intraoperative parathyroid hormone measurement as a day-case procedure (Br J Surg 2004; 91: 78,82)

BRITISH JOURNAL OF SURGERY (NOW INCLUDES EUROPEAN JOURNAL OF SURGERY), Issue 7 2004
W.T. Ng
No abstract is available for this article. [source]

Osteoporosis and inflammatory bowel disease

ALIMENTARY PHARMACOLOGY & THERAPEUTICS, Issue 9 2004
C. N. Bernstein
Summary Studies using dual-energy X-ray absorptiometry have suggested a high prevalence of osteoporosis in inflammatory bowel disease. However, population-based data on fracture incidence suggest only a small increased risk of fracture amongst patients with inflammatory bowel disease compared with the general population. Therefore, it would be helpful to identify patients with inflammatory bowel disease at particularly high risk for fracture so that these risks might be modified or interventions might be undertaken. The data on calcium intake as a predictor of bone mineral density are conflicting. Although there are data suggesting that a one-time survey to determine current calcium intake will not help to predict bone mineral density in inflammatory bowel disease, persistently reduced calcium intake does appear to lead to lower bone mineral density. In the general population, body mass is strongly correlated with bone mineral density, which also appears to be true in Crohn's disease. Hence, subjects with inflammatory bowel disease and considerable weight loss, or who are obviously malnourished, could be considered for bone mineral density testing, and the finding of a low bone mineral density would suggest the need for more aggressive nutritional support. Although vitamin D is undoubtedly important in bone health, vitamin D intake and serum vitamin D levels do not correlate well with bone mineral density. Sex hormone deficiency can also adversely affect bone health, although a well-developed strategy for sex hormone measurements in patients with inflammatory bowel disease remains to be established. Ultimately, the determination of genetic mutations that accurately predict fracture susceptibility may be the best hope for developing a simplified strategy for managing bone health in inflammatory bowel disease. The therapy of osteoporosis in inflammatory bowel disease has been adapted from other osteoporosis settings, such as post-menopausal or corticosteroid-induced osteoporosis. To date, there remains no therapy proven to be efficacious in inflammatory bowel disease-related osteoporosis; however, calcium and vitamin D supplementation and bisphosphonates have their roles. [source]

Serum concentrations of 17,-E2 and 25-hydroxycholecalciferol (25OHD) in relation to all-cause mortality in older men , the MINOS study

CLINICAL ENDOCRINOLOGY, Issue 4 2009
Pawel Szulc
Summary Objective, To examine the association of serum hormone levels with all-cause mortality in older community-dwelling men. Design, Single centre cohort study. Subjects, Men aged 50 and older, insured by Société de Secours Minière de Bourgogne (Montceau les Mines, France). Among 3400 men invited to participate, 782 volunteers had serum hormone measurements and were followed up for 10 years. No exclusion criteria were used. Results, Nonsurvivors (n = 182) were older, had more comorbidities and lower physical performance. The lowest quartile of 25-hydroxycholecalciferol (25OHD) level predicted mortality [HR = 1·44, 95% confidence interval (CI): 1·03,2·03, P < 0·05] regardless of age, BMI, smoking, physical activity, vitamin D supplementation, and health status; mainly for the first 3 years. The 17,-E2 level predicted mortality independent of confounders after the third year (HR = 1·21 per 1 SD increase, 95% CI: 1·09,1·35, P < 0·001). In the fully adjusted models, risk of death increased per quartiles of 17,-E2 (trend ,P < 0·001) and was higher in the third and the fourth quartiles compared with the lowest quartile (HR = 1·80, 95% CI: 1·09,2·98, P < 0·05 and HR = 2·83, 95% CI: 1·71,4·67, P < 0·001). Concentrations of testosterone and PTH did not predict mortality independent of the model. Conclusions, In older men, increased 17,-E2 level predicted mortality after 3 years of follow-up. Thus, high 17,-E2 level may reflect presence of risk factors precipitating development of diseases. Low 25OHD level predicted mortality more weakly, mainly for the first 3 years of the follow-up, and was strongly influenced by the confounding variables. Thus, low 25OHD level may reflect poor current health status and unhealthy lifestyle. [source]