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Horizontal Bone Loss (horizontal + bone_loss)
Selected AbstractsAn improved cost-effective, reproducible method for evaluation of bone loss in a rodent modelJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 2 2009Daniel H. Fine Abstract Aim: This study was designed to investigate the utility of two "new" definitions for assessment of bone loss in a rodent model of periodontitis. Material and Methods: Eighteen rats were divided into three groups. Group 1 was infected by Aggregatibacter actinomycetemcomitans (Aa), group 2 was infected with an Aa leukotoxin knock-out, and group 3 received no Aa (controls). Microbial sampling and antibody titres were determined. Initially, two examiners measured the distance from the cemento-enamel-junction to alveolar bone crest using the three following methods; (1) total area of bone loss by radiograph, (2) linear bone loss by radiograph, (3) a direct visual measurement (DVM) of horizontal bone loss. Two "new" definitions were adopted; (1) any site in infected animals showing bone loss >2 standard deviations above the mean seen at that site in control animals was recorded as bone loss, (2) any animal with two or more sites in any quadrant affected by bone loss was considered as diseased. Results: Using the "new" definitions both evaluators independently found that infected animals had significantly more disease than controls (DVM system; p<0.05). Conclusions: The DVM method provides a simple, cost effective, and reproducible method for studying periodontal disease in rodents. [source] Bone resorbing activity and cytokine levels in gingival crevicular fluid before and after treatment of periodontal diseaseJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 6 2004Anders Holmlund Abstract Background: The aim of the present study was to investigate bone resorption activity (BRA), interleukin-1, (IL-1,), IL-1, and interleukin-1 receptor antagonist (IL-1ra) in gingival crevicular fluid (GCF) in sites with no signs of periodontol disease and in sites with horizontal or angular loss of periodontal bone. These assessments were performed before and after periodontal treatment. Methods: GCFs were collected from 10 individuals with filter strips from two healthy sites and four sites with deep pathological periodontal pockets, two of which showed horizontal bone loss and two with angular bone loss. All diseased pockets were treated with flap surgery and systemic Doxyferm®. Twelve months later GCF was collected again and treatment outcome evaluated. BRA in GCFs was assessed in a bone organ culture system by following the release of 45Ca from neonatal mouse calvariae. The amounts of IL-1,, IL-1, and IL-1ra in GCFs were quantified by enzyme-linked immunosorbent assay (ELISA). Results: Treatment resulted in reduction of pocket depths with 3.5±0.5 mm in sites with angular bone loss and 2.8±0.3 mm in sites with horizontal bone loss. Initially, BRA, IL-1,, IL-1, and IL-1ra were significantly higher in GCFs from diseased sites compared with healthy sites. No differences in BRA and cytokine levels were seen between GCFs from pockets with horizontal and angular bone losses. The levels of IL-1,, IL-1, and IL-1ra were significantly reduced after treatment of diseased pockets. Pocket depths were significantly correlated to BRA only in pre-treatment sites with angular bone loss. BRA was correlated to Il-1,, IL-1,, but not to IL-1ra, in diseased sites with angular bone loss, before and after treatment. The reductions of BRA in the individual sites, seen after treatment, were not correlated to the reductions of Il-1,, IL-1, or IL-1ra. Conclusions: These data show that BRA and cytokine levels are increased in GCFs from sites with periodontal disease and that periodontal treatment results in reduction of the cytokines. Our findings further indicate that IL-1, and IL-1, play important roles for the BRA present in GCFs, but that other factors also contribute to this activity. [source] Radiographic periodontal attachment loss as an indicator of death risk in the elderlyJOURNAL OF CLINICAL PERIODONTOLOGY, Issue 2 2000K. Soikkonen Abstract Objectives: Oral infections have been associated with serious systemic diseases and an increased risk of death. Our aims were to investigate whether radiographically-observed apical periodontitis lesions, carious teeth, periodontal attachment loss (horizontal bone loss, furcation lesions, number of teeth with infrabony periodontal pockets, the extent of infrabony periodontal pockets) and the sum of all these findings have any relationships with all-cause mortality within 4-year follow-up. Material and methods: 292 community-dwelling elderly persons aged 76, 81 and 86 years. The number of deaths within 4 years was 54 (18.5%). In the dentate 169 subjects, of whom 32 (18.9%) deceased within 4 years, the mean number of teeth was 15.5 in men and 13.2 in women. The imaging method used was panoramic radiography supplemented by intraoral radiographs. Results: 51% of the dentate subjects had infrabony pockets (mean 1.5, s.d. 2.2), and 40% had periapical periodontitis lesions (mean 1.0, s.d. 1.6). After controlling for age and gender, vertical bone loss judged as advanced infrabony pockets was associated with 4-year all-cause mortality (Odds ratio 2.2,1.0,4.7). Other associations were statistically insignificant. Conclusion: Periodontal attachment loss may indicate an increased risk of death in the elderly. [source] Resilient liner vs. clip attachment effect on peri-implant tissues of bar-implant-retained mandibular overdenture: a 1-year clinical and radiographical studyCLINICAL ORAL IMPLANTS RESEARCH, Issue 5 2010Moustafa Abdou Elsyad Abstract Purpose: The aim of this study was to compare between the effects of resilient liner and clip attachments of bar-implant-retained mandibular overdenture on peri-implant tissues. Materials and methods: In a randomized-controlled clinical trial, 30 edentulous male patients (mean age 62.5 years) were equally assigned to two groups. In each patient, two implants were inserted in the canine area of the mandible using a two-stage surgical protocol. After 3 months, the implants were connected with resilient bars. Mandibular overdentures were retained to the bars with either clips (group I) or silicone-resilient liners (group II). Peri-implant tissues were evaluated clinically (with regard to plaque scores, gingival scores and probing depths) and radiographically (with regard to peri-implant vertical and horizontal alveolar bone changes). Evaluations were performed at the time of overdenture insertion (T0), 6 months (T6) and 12 months (T12) after overdenture insertion. Results: After 12 months of using bar-implant-retained mandibular overdenture, the resilient liner attachment had significantly decreased peri-implant plaque score, gingival score, probing depth, vertical and horizontal bone loss when compared with the clip attachment. Conclusion: Within the limitations of this study, and in terms of peri-implant tissue health of bar-implant-retained mandibular overdenture, we recommend resilient liner rather than clip attachment. To cite this article: Elsyad MA, EL Shoukouki AH. Resilient liner vs. clip attachment effect on peri-implant tissues of bar-implant-retained mandibular overdenture: a 1-year clinical and radiographical study. Clin. Oral Impl. Res. 21, 2010; 473,480 doi: 10.1111/j.1600-0501.2009.01879.x [source] | ||||||||||