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Highly Regio (highly + regio)
Selected AbstractsA Facile Synthesis of Lentiginosine Analogues Based on a Highly Regio- and Diastereoselective Allylic Amination Using Chlorosulfonyl IsocyanateEUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 8 2010In Su Kim Abstract The concise synthesis of the lentiginosine analogues pyrrolizidine alkaloid 2 and pyrroloazepine alkaloid 3 has been achieved from inexpensive and readily available D -lyxose. The key steps in the synthesis included regio- and diastereoselective amination, inter- or intramolecular olefin metathesis, and Appel cyclization. The anti -3,4-amino alcohol 6, essential for the preparation of the title compounds 2 and 3, was synthesized by the regio- and diastereoselective amination of anti -3,4-tribenzyl ether 7 using chlorosulfonyl isocyanate. The reaction of 7 with chlorosulfonyl isocyanate in toluene at 0 °C afforded 6 exclusively with a diastereoselectivity of 26:1 in 84,% yield. These results can be explained by the neighboring-group effect, which leads to retention of thestereochemistry. [source] Ferric Chloride Hexahydrate-Catalyzed Highly Regio- and Stereoselective Conjugate Addition Reaction of 2,3-Allenoates with Grignard Reagents: An Efficient Synthesis of ,,,-AlkenoatesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 11-12 2009Guobi Chai Abstract Ferric chloride hexahydrate was shown to be an efficient catalyst for the conjugate addition of 2,3-allenoates with alkyl-, aryl-, or vinyl-Grignard reagents to synthesize polysubstituted ,,,-unsaturated alkenoates with high regio- and stereoselectivity. The in situ formed magnesium dienolate may readily react with different electrophilic reagents under different reaction conditions with or without a catalyst to construct an allylic quaternary carbon at the ,-position of the ester group and a stereocontrollable retention of the carbon-carbon double bond. [source] ChemInform Abstract: Highly Regio- and Stereoselective Intermolecular Tandem Reaction to Synthesize Chloro-substituted 1,3-Butadienes.CHEMINFORM, Issue 24 2010Jing-Mei Huang Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Unexpected High Regiocontrol in Heck Reaction of Fluorine-Containing Electron-Deficient Olefins , Highly Regio- and Stereoselective Synthesis of ,-Fluoroalkyl-,-aryl-,,,-unsaturated Ketones.CHEMINFORM, Issue 7 2010Tsutomu Konno Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: CAN-Mediated Highly Regio- and Stereoselective Oxidation of Vinylidenecyclopropanes: A Novel Method for the Synthesis of Unsymmetrical Divinyl Ketone and Functional Enone Derivatives.CHEMINFORM, Issue 51 2008Chenliang Su Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Sequence of Intramolecular Carbonylation and Asymmetric Hydrogenation Reactions: Highly Regio- and Enantioselective Synthesis of Medium Ring Tricyclic Lactams.CHEMINFORM, Issue 40 2008Shui-Ming Lu Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Highly Regio-, Diastereo-, and Enantioselective [2 + 2 + 2] Cycloaddition of 1,6-Enynes with Electron-Deficient Ketones Catalyzed by a Cationic Rh(I)/H8 -binap Complex.CHEMINFORM, Issue 24 2008Ken Tanaka Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Thiourea to Dithiazolopyrimidines: Highly Regio- and Stereoselective Synthetic Routes via Mercaptoacetylative Cyclization.CHEMINFORM, Issue 20 2008Lal Dhar S. Yadav Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Highly Regio- and Stereoselective [2 + 3] Cycloadditions of Azomethine Ylides to [70]Fullerene.CHEMINFORM, Issue 15 2008Pavel A. Troshin Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] A Highly Regio- and Stereoselective Formation of Bicyclo[4.2.0]oct-5-ene Derivatives Through Thermal Intramolecular [2 + 2] Cycloaddition of Allenes.CHEMINFORM, Issue 42 2007Hiroaki Ohno Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] A Highly Regio- and Chemoselective Synthesis of Vicinal Bromohydrins by Ring Opening of Terminal Epoxides with Dibromoborane,Dimethyl Sulfide.CHEMINFORM, Issue 27 2007Chandra D. Roy Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Metal Triflate Catalyzed Highly Regio- and Stereoselective 1,2-Bromoazidation of Alkenes Using NBS and TMSN3 as the Bromine and Azide Sources.CHEMINFORM, Issue 1 2007Saumen Hajra Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source] Syntheses of Vinylindoles via a Broensted Acid Catalyzed Highly Regio- and Stereoselective cis-Hydroarylation of Ynamides.CHEMINFORM, Issue 52 2005Yanshi Zhang Abstract For Abstract see ChemInform Abstract in Full Text. [source] A Highly Regio- and Chemoselective Reductive Cleavage of Benzylidene Acetals with EtAlCl2,Et3SiH.CHEMINFORM, Issue 30 2004Vijayakrishnan Balakumar Abstract For Abstract see ChemInform Abstract in Full Text. [source] A Novel Highly Regio- and Diastereoselective Haloamination of Alkenes Catalyzed by Divalent Palladium.CHEMINFORM, Issue 24 2004Aiwen Lei Abstract For Abstract see ChemInform Abstract in Full Text. [source] Palladium-Catalyzed Highly Regio-, Stereo- and Chemoselective Carbogermanylation of Allenes: A Novel Method for the Synthesis of 2-Arylallylgermane Derivatives.CHEMINFORM, Issue 43 2003Masilamani Jeganmohan Abstract For Abstract see ChemInform Abstract in Full Text. [source] 6-exo-Spiro (Alkoxycarbonylamino)methyl Radical Cyclization: Highly Regio- and Stereoselective Synthesis of (-)-Sibirine.CHEMINFORM, Issue 3 2003Masato Koreeda No abstract is available for this article. [source] ChemInform Abstract: Practical and Highly Regio- and Stereoselective Synthesis of 2-Substituted Dihydropyridines and Piperidines: Application to the Synthesis of (-)-Coniine.CHEMINFORM, Issue 17 2002Andre B. Charette Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Palladium,Copper Catalyzed Synthesis of Benzofused Heterocycles with Two Heteroatoms: Novel and Highly Regio- and Stereoselective Syntheses of (E)-2-(2-Arylvinyl)-3-tosyl-2,3-dihydro-1,3-benzothiazoles and (E)-2-Alkyl(aryl)idene-3,4-dihydro-2H-1,4-benzothiazines.CHEMINFORM, Issue 46 2001Nitya G. Kundu Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Copper-Catalyzed Heteroannulation with Alkynes: A General and Highly Regio- and Stereoselective Method for the Synthesis of (E)-2-(2-Arylvinyl) Quinazolinones.CHEMINFORM, Issue 45 2001Nitya G. Kundu Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] ChemInform Abstract: Highly Regio- and Stereo-Controlled Pd(0)-Catalyzed Nucleophilic Substitution Reaction for the Synthesis of Optically Active ,-Fluoroalkylated Allylic Alcohols.CHEMINFORM, Issue 4 2001Tsutomu Konno Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source] [PdCl2(MeCN)2]-Catalyzed Highly Regio- and Stereoselective Allylation of Electron-Rich Arenes with 2,3-AllenoatesCHEMISTRY - A EUROPEAN JOURNAL, Issue 13 2010Zhao Fang Selective allylation: Several electron-donating arenes such as 1,3,5-trimethoxybenzene, anisole, and phenol underwent palladium-catalyzed selective allylation in TFA/dimethylacetamide (DMA) under mild conditions with 2,3-allenoates (see scheme). The reaction afforded substituted 4,4-diarylbut-2(E)-enoates in moderate yields with high regio- and stereoselectivity. [source] Enantioselective Synthesis of 3-Azabicyclo[4.1.0]heptenes and 3-Azabicyclo[3.2.0]heptenes by Ir-Catalyzed Asymmetric Allylic Amination of N -Tosyl Propynylamine and Pt-Catalyzed CycloisomerizationCHEMISTRY - A EUROPEAN JOURNAL, Issue 22 2010Ji-Bao Xia Irresistible! Highly regio- and enantioselective Ir-catalyzed allylic amination reactions of N -tosyl propynylamines have been realized. The resulting N -tosyl allylpropynylamines were transformed into highly enantioenriched 3-azabicyclo[4.1.0]heptenes and 3-azabicyclo[3.2.0]heptenes, respectively, in the presence of PtCl2 (see scheme; Ts=tosyl, cod=1,5-cyclooctadiene, TBAF=tetrabutylammonium fluoride, TMS=trimethylsilyl). [source] Highly Regio- and Stereoselective Iodohydroxylation of Non- Heteroatom-Substituted Allenes: An Efficient Synthesis of 4-[3,-Hydroxy-2,-iodoalk-1,(Z)-enyl]-2(5H)-furanone DerivativesADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 10 2007Zhenhua Gu Abstract An efficient protocol for the highly regio- and stereoselective synthesis of 4-(3,-hydroxy-2,-iodoalk-1,(Z)-enyl)furan-2(5H)-one derivatives via selective iodohydroxylation of non-heteroatom-substituted allenes, i.e., 4-allenyl-2(5H)furanones, has been developed. The regio- and stereoselectivity of this reaction may be controlled by the electronic and steric effects of the furanone ring. [source] Highly Regio- and Stereoselective Copper(I) Chloride-Mediated Carbometallation of 2,3-Allenols with Grignard ReagentsADVANCED SYNTHESIS & CATALYSIS (PREVIOUSLY: JOURNAL FUER PRAKTISCHE CHEMIE), Issue 7 2007Zhan Lu Abstract An efficient highly regio- and stereoselective copper(I) chloride-mediated carbometallation of differently substituted 2,3-allenols with primary or secondary alkyl or aromatic Grignard reagents followed by iodination to synthesize fully-substituted allylic alcohols has been developed. This protocol introduces the R4 group from the Grignard reagent to the terminal position of the 2,3-allenols. [source] Highly Efficient Access to Bi- and Tricyclic Ketals through Gold-Catalyzed Tandem Reactions of 4-Acyl-1,6-diynesCHEMISTRY - A EUROPEAN JOURNAL, Issue 8 2009Jia Meng Dr. Abstract Single step: Fused bicyclic and bridged tricyclic ketals were synthesized in a single step from the reactions of easily available 4-acyl-1,6-diynes with H2O and alkanols (see scheme). The highly efficient AuCl3 -catalyzed multicomponent domino reactions, involving five CO bond formations, can proceed in a highly regio- and diastereoselective manner at room temperature under air and lead to structures of high molecular complexity from simple starting materials in an atom economic way. [source] Cobalt- and Nickel-Catalyzed Regio- and Stereoselective Reductive Coupling of Alkynes, Allenes, and Alkenes with AlkenesCHEMISTRY - A EUROPEAN JOURNAL, Issue 35 2008Masilamani Jeganmohan Dr. Abstract Transition-metal-catalyzed coupling of two different CC , components through a metallacycle intermediate is a highly atom economical method to construct CC bonds in organic synthesis. The metal-catalyzed coupling of an alkene and alkyne generally gives an Alder-ene or reductive coupling product. In this article, we focus on the cobalt- and nickel-catalyzed reductive coupling of alkynes, allenes, and alkenes with alkenes. These reductive coupling reactions provide convenient methods for the synthesis of various alkenes, dienes, functionalized alkanes, lactones, lactams, and cyclic alcohols in a highly regio- and stereoselective manner. A chemselective formation of metallacyclopentene intermediate from the two different CC , components and a low-valence metal species plays a key role for the high regio- and stereoselectivity of the catalytic reaction. [source] | ||||||||||