Home  About us  Contact
 

Highly Diastereoselective Addition (highly + diastereoselective_addition)

Distribution by Scientific Domains
Chemistry100%

Selected Abstracts

ChemInform Abstract: Highly Diastereoselective Addition of Alkynylmagnesium Chlorides to N-tert-Butanesulfinyl Aldimines: A Practical and General Access to Chiral ,-Branched Amines.

CHEMINFORM, Issue 22 2010
Bai-Ling Chen
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

ChemInform Abstract: Highly Diastereoselective Addition of Allyltitanocenes to Ketones.

CHEMINFORM, Issue 28 2009
Yasutaka Yatsumonji
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

Rapid, Highly Diastereoselective Addition of Dialkylzinc Reagents to Atropisomeric 2-Formyl Arylamides.

CHEMINFORM, Issue 36 2004
Ciril Jimeno
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

First Synthesis of Optically Pure Propargylic N-Hydroxylamines by Direct, Highly Diastereoselective Addition of Terminal Alkynes to Nitrones.

CHEMINFORM, Issue 51 2002
Roger Faessler
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

Asymmetric Synthesis of ES-285, an Anticancer Agent Isolated from Marine Sources

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 35 2009
Ana C. Allepuz
Abstract The asymmetric synthesis of (2S,3R)-2-amino-3-octanedecanol hydrochloride (ES-285·HCl) was achieved in eight steps in ca. 38,% overall yield from the N -benzylimine-derived from (R)-2,3- O -isopropylidene glyceraldehyde, which is easily available on gram scale from the inexpensive precursor D -mannitol. Highly diastereoselective addition of methylmagnesium bromide to the N -benzylimine was the key step to create the vic -amino alcohol moiety with the appropriate configuration. Regioselective ring opening of an intermediate aminoepoxide enabled the introduction of the long hydrocarbon chain at C4.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009) [source]

Synthesis of Enantiopure 1-Aryl-1-butylamines and 1-Aryl-3-butenylamines by Diastereoselective Addition of Allylzinc Bromide to Imines Derived from (R)-Phenylglycine Amide

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 7 2004
Jan Dalmolen
Abstract The synthesis of enantiopure 1-aryl-1-butylamines via a highly diastereoselective addition of allylzinc bromide to imines derived from (R)-phenylglycine amide is reported. These are synthesised by a three-step procedure, which involves: (a) formation of the chiral imines; (b) asymmetric addition of the allylzinc reagent; (c) removal of the chiral auxiliary by means of a reductive or non-reductive method. The reductive method provides 1-aryl-1-butylamines whereas the non-reductive method preserves the double bond to afford 1-aryl-3-butenylamines. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004) [source]

Syntheses of New Chiral Phosphane Ligands by Diastereoselective Conjugate Addition of Phosphides to Enantiomerically Pure Acceptor-Substituted Olefins from the Chiral Pool

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 15 2005
Burkhard Wiese
Abstract A variety of new chiral phosphanes were prepared by highly diastereoselective additions of phosphanes to ,,,-unsaturated carbonyl compounds and related acceptor-substituted olefins derived from myrtenal as ex chiral pool source. Monophosphanes with astereogenic as well as stereogenic phosphorus are described. In addition diphosphanes were prepared by a highly diastereoselective double conjugate addition of a secondary diphosphane. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005) [source]