Highest Priority (highest + priority)

Distribution by Scientific Domains


Selected Abstracts


Using Phylogenetic Diversity Measures to Set Priorities in Conservation: an Example from Southern South America

CONSERVATION BIOLOGY, Issue 5 2001
Paula Posadas
The goal of these ranks for conservation is to consider as many factors as possible that provide additional taxic information, such as taxa richness, taxa distributional patterns, area endemicity, and complementarity between areas. At present there are many measures that consider phylogenetic information, including node-based, genetic-distance, and feature-based measures. We devised a modified phylogenetic node-based index that we call "taxonomic endemicity standardized weight," which considers not only the taxonomic distinctness of the taxa that inhabit a given area but their endemicity as well. Once the standardized weight of the taxonomic endemicity identifies the area of highest priority, complementarity can be used to identify the second area and so on. We used this node-based index to rank priority areas for conservation in southern South America, and we compared the results of our rankings to results based on other node-based indexes. Our index identified Santiago district, in Central Chile province, as the highest priority area for conservation, followed by Maule, Malvinas, and districts of Subantarctic province. Malvinas exhibits greater complementarity relative to Santiago than Maule does, however, so Malvinas is ranked second in priority. Indexes based on phylogenetic information measure the evolutionary component of biodiversity and allow one to identify areas that will ensure the preservation of evolutionary potential and phylogenetically rare taxa. The modified index we propose is sensitive to taxic distinctness and endemicity as well and allows information from diverse taxa to be combined (i.e., different cladograms). The use of complementarity allows for preservation of the maximum quantity of taxa in a minimal number of protected areas. Resumen: Las medidas de diversidad filogenética jerarquiza a las áreas para prioridades de conservación de biodiversidad con base en información codificada en filogenias (cladogramas), La meta de estas categorías de conservación requiere tomar en consideración tantos factores que proporcionan información adicional (riqueza de taxones, patrones de distribución de los taxones, endemicidad del área y complementariedad entre áreas) como sea posible. Actualmente hay muchas medidas que consideran información filogenética (basadas en nodos, distancia genética y basadas en características). Diseñamos un índice filogenético modificado basado en nodos que denominamos "peso estandarizado de endemicidad taxonómica", el cual considera no solo la peculiaridad genética de los taxa que habitan una región determinada sino también su endemicidad. Una vez que el peso estandarizado de endemicidad identifica el área de mayor prioridad, la complementariedad se puede usar para identificar la segunda área y así sucesivamente. Utilizamos este índice basado en nodos para jerarquizar áreas prioritarias para conservación en el sur de América del Sur, y comparamos los resultados de nuestras jerarquizaciones con resultados obtenidos con otros índices basados en nodos. Nuestro índice identificó al distrito de Santiago, en la provincia de Chile Central, como el área de mayor prioridad para conservación, seguido por Maule, Malvinas y distritos de la provincia Subantártica. Sin embargo, Malvinas presenta mayor complementariedad en relación con Santiago que el Maule y, por tanto, Malvinas ocupa la segunda prioridad. Los índices basados en información filogenética miden el componente evolutivo de la biodiversidad y permiten la identificación de áreas que aseguran la preservación de taxones con potencial evolutivo y filogenéticamente peculiares. El índice modificado que proponemos es sensible tanto a la peculiaridad de los taxones como a la endemicidad y permite combinar información de diversos taxones (i.e. cladogramas diferentes). El uso de la complementariedad permite la preservación de la mayor cantidad de taxones en un número mínimo de áreas protegidas. [source]


Haemophilia 2002: emerging risks of treatment

HAEMOPHILIA, Issue 3 2002
B. L. EVATT
Haemophilia care and treatment products have greatly improved over the past 2 decades. Transitions in treatment produced by these changes were accompanied by the emergence of unexpected risks and new complications. In order to provide the best comprehensive care to patients with haemophilia, healthcare providers periodically need to re-evaluate and adjust their management and therapeutic products to prevent or minimize the effects produced by the emerging issues. For example, reducing the effects of infectious agents remains the highest priority for the haemophilia community because of the high level of morbidity and mortality that has resulted from earlier therapeutic agents. In many countries, the goal has been to achieve absolute zero risk for infectious agents. In some instances, the screening procedures to achieve these goals reduced the availability of plasma needed for manufactured derivatives and produced another emerging risk, shortages of clotting factor preparations. Similarly, better diagnostic methods identified other potential agents that were not inactivated by current technology. Likewise, immune tolerance regimens and the prophylactic management of haemophilia introduced different therapeutic delivery systems with their own risks. The drugs used to manage diseases such as human immunodeficiency virus (HIV), which were transmitted by products manufactured before mid-1980, create their own set of risks for this community. Topical emerging risks of treatment, including variant Creutzfeldt,Jakob disease, an assessment of its risks and impact, the complications of using indwelling catheters, and the role of protease inhibitors used to treat HIV may have on bleeding complications of haemophilia are discussed. [source]


Systematic design method of stabilization fuzzy controllers for pendulum systems

INTERNATIONAL JOURNAL OF INTELLIGENT SYSTEMS, Issue 8 2001
Jianqiang Yi
A systematic method to construct stabilization fuzzy controllers for a single pendulum system and a series-type double pendulum system is presented based on the single input rule modules (SIRMs) dynamically connected fuzzy inference model. The angle and angular velocity of each pendulum and the position and velocity of the cart are selected as the input items. Each input item is given with a SIRM and a dynamic importance degree. All the SIRMs have the same rule setting. The dynamic importance degrees use the absolute value(s) of the angle(s) of the pendulum(s) as the antecedent variable(s). The dynamic importance degrees are designed such that the upper pendulum angular control takes the highest priority and the cart position control takes the lowest priority when the upper pendulum is not balanced upright. The control priority orders are automatically adjusted according to control situations. The simulation results show that the proposed fuzzy controllers have high generalization ability to completely stabilize a wide range of single pendulum systems and series-type double pendulum systems in short time. By extending the architecture, a stabilization fuzzy controller for a series-type triple pendulum system is even possible. © 2001 John Wiley & Sons, Inc. [source]


Effects of nitrogen supply on water-use efficiency of higher plants

JOURNAL OF PLANT NUTRITION AND SOIL SCIENCE, Issue 2 2008
Holger Brueck
Abstract The worldwide increase of food demand and reduced sweet-water availability in some important food-producing regions raised interest in more efficient water use, which has become one of the central research topics in agriculture. Improved irrigation management and reduced bare-soil evaporation have highest priority to increase agronomic water-use efficiency (WUE). Compared to these technical (irrigation) and basic (crop production) management options, effects of nutrient management on WUE were less frequently considered. Twenty-nine publications on nitrogen (N) effects on biomass WUE of container-grown plants are considered in this review. Most of them indicate positive N effects on WUE, and relevance of N effects on intrinsic WUE and unproductive water and carbon loss is discussed. A plot of 90 published data of percent decreases of WUE and dry mass under variable N supply is presented. Extrapolation of biomass WUE from leaf measurements of intrinsic WUE is critically reviewed. The positive correlation between WUE and dry-mass formation suggests that physiological rather than stomatal effects are more important in order to explain positive N effects on WUE. [source]


Association Between Quality of Cheap and Unrecorded Alcohol Products and Public Health Consequences in Poland

ALCOHOLISM, Issue 10 2009
Dirk W. Lachenmeier
Background:, The research aimed to study the quality of cheap alcohol products in Poland. These included unrecorded alcohols (i.e., home-produced or illegally imported), estimated to constitute more than 25% of total consumption and fruit wines. Methods:, A sample of alcohol products (n = 52) was collected from local markets and chemical analyses were conducted. The parameters studied were alcoholic strength, volatiles (methanol, acetaldehyde, and higher alcohols), ethyl carbamate, inorganic elements, and food additives including preservatives, colors, and sweeteners. The compositions of the beverages were then toxicologically evaluated using international standards. Results:, With the exception of 1 fortified wine, the unrecorded alcohols were home-produced fruit-derived spirits (moonshine) and spirits imported from other countries. We did not detect any nonbeverage surrogate alcohol. The unrecorded spirits contained, on average, 45% vol of alcohol. However, some products with considerably higher alcoholic strengths were found (up to 85% vol) with no labeling of the content on the bottles. These products may cause more pronounced detrimental health effects (e.g., liver cirrhosis, injuries, some forms of malignant neoplasms, alcohol use disorders, and cardiovascular disease) than will commercial beverages, especially as the consumer may be unaware of the alcohol content consumed. Fruit wines containing between 9.5 and 12.2% vol alcohol showed problems in terms of their additive content and their labeling (e.g., sulfites, sorbic acid, saccharin, and artificial colors) and should be subjected to stricter control. Regarding the other components investigated, the suspected human carcinogens, acetaldehyde and ethyl carbamate, were found at levels relevant to public health concerns. While acetaldehyde is a typical constituent of fermented beverages, ethyl carbamate was found only in home-produced unrecorded alcohols derived from stone fruits with levels significantly above international guidelines. Conclusions:, The contamination of unrecorded alcohols with ethyl carbamate should be analyzed in a larger sample that also should include legal alcoholic beverages. Furthermore, the impacts of unrecorded alcohol on the health of people with lower socioeconomic status should be studied in detail. Overall, given the extent of the alcohol-attributable disease burden in Poland, the highest priority should be given to the problem of ethanol and its very high content in unrecorded alcohol products. [source]


Stakeholder appraisal of policy options for responding to obesity in Italy

OBESITY REVIEWS, Issue 2007
B. De Marchi
Summary This article deals with the phenomenon of obesity in contemporary Italian society. It is based on the fieldwork carried out during the year 2005 within the European Union-funded project ,PorGrow: policy options for responding to obesity' (see: http://www.sussex.ac.uk/spru/PorGrow). The most recent statistical data on the spread of overweight and obesity in Italian society reveal that the phenomenon has reached a dimension that, albeit not as serious as in other Western countries, constitutes a serious threat to public health and to the national budget. The panel of stakeholders interviewed for this research showed awareness of this issue and generally agreed on the necessity to adopt a very multifaceted portfolio of policy measures to address the problem. Participants frequently regarded educational policies as the highest priority, followed by informational measures and infrastructural actions. Fiscal policy options were widely considered ineffective and unacceptable, and little enthusiasm was shown for technological innovations. In sum, while interviewees saw a real need for improved food habits on the part of Italian citizens, nonetheless in a country affected by many criticalities, the weakness of political will and the pressure of fast food culture remain severe obstacles in the fight against overweight and obesity. [source]


Understanding the Impacts of the Medicare Modernization Act: Concerns of Congressional Staff

THE JOURNAL OF RURAL HEALTH, Issue 3 2005
Keith J. Mueller PhD
ABSTRACT: Sweeping changes to the Medicare program embodied in the Medicare Prescription Drug, Improvement, and Modernization Act of 2003 (MMA), including a new prescription drug benefit, changes in payment policies, and reform of the Medicare managed-care program, have major implications for rural health care. The most efficient mechanism for research to affect policy is to provide policy makers with information on issues about which they have voiced concern. The Rural Policy Research Institute's Health Panel conducted 2 focus groups with 16 congressional staff in September 2004 to identify a set of researchable questions concerning the impact of the MMA on rural health care. This paper presents research questions in the following areas that staff identified as having the highest priority: access to health plans and pharmacy services, beneficiary outreach and enrollment, technology capacity, provider payment policy, and demonstration projects. [source]


Facial transplantation as an option in reconstructive surgery: no mountains too high?

ANZ JOURNAL OF SURGERY, Issue 12 2009
Wojciech B, ogowski
Abstract Background:, Human facial allotransplantation (FA) is a testament to the impressive progress, which was and is still happening in the field of transplantation medicine and reconstructive surgery. Like every pioneering treatment option, FA faces both the clinicians' and public opinion with a huge amount of medical and psychosocial dilemmas, which, in order to introduce FA as a scientifically and socially accepted procedure into clinical practice, need to be discussed, answered and solved. Methods:, This review is based on a detailed literature research in all relevant databases (MEDLINE, PubMed, Cochrane Library, specialist textbooks), however, recent papers (published between 2006 and 2008) were given highest priority for inclusion. Results:, In this review, two main limitations associated with facial tissue allotransplantation, that is, shortage of donations and life-long need for immunosuppressive treatment, are discussed and presented in both psychosocial and medical terms. Conclusion:, Although both of these limitations potentially could successfully inhibit the transformation of FA from an experimental therapy to the treatment of choice for patients with severe functional facial impairment, recent literature suggest that FA will find a meaningful place in facial reconstructive surgery. [source]


Diversity, conservation status and threats to native oysters (Ostreidae) around the Atlantic and Caribbean coasts of South America

AQUATIC CONSERVATION: MARINE AND FRESHWATER ECOSYSTEMS, Issue 3 2009
Alvar Carranza
Abstract 1.Despite the extensive literature on the ecology, systematics and culture of oysters worldwide, an assessment of their diversity, distribution and conservation status for the Atlantic and Caribbean coasts (i.e. depth <50 m) of South America is lacking. Such information is crucial because of the increasing coastal development that threatens most nearshore habitats throughout the region. 2.The available information on oysters on Atlantic and Caribbean coasts is reviewed with a focus on identifying regional conservation priorities based on ecological and socio-economic importance, as well as the magnitude of current or potential threats faced by oyster populations. The current status of ,- taxonomy within the Ostreidae was also examined. 3.Ten species of native Ostreidae (plus three introduced species) inhabit the coastal waters of the Atlantic and Caribbean coasts of South America. 4.Oyster species were ranked according to their biological/ecological and socio-economic value and conservation status within 10 distinct ecoregions. Crassostrea gasar in the Eastern Brazil ecoregion, C. rhizophorae in the Central Caribbean ecoregion and Ostrea puelchana in the North Patagonian Gulfs ecoregion should receive the highest priority for immediate conservation action due to extensive loss of mangrove habitat in the two former regions and evidence of decline of one of the most important populations for the latter. The need for a standardized methodology to assess the status of oyster populations throughout the ecoregions is identified. 5.On a local scale, the allocation of territorial use rights for fisheries under a collaborative/voluntary community framework is strongly advocated to fulfil management, conservation and poverty alleviation goals in these developing countries. Copyright © 2008 John Wiley & Sons, Ltd. [source]