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High Total (high + total)
Selected AbstractsProspective Association Between Low and High Total and Low-Density Lipoprotein Cholesterol and Coronary Heart Disease in Elderly MenJOURNAL OF AMERICAN GERIATRICS SOCIETY, Issue 12 2004J. David Curb MD Objectives: To examine the relationship between total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and the incidence of coronary heart disease (CHD) in elderly men. Design: Prospective. Setting: Population based. Participants: A sample of 2,424, Japanese-American men aged 71 to 93 was used. Measurements: Six years of data on incident fatal plus nonfatal CHD were examined. Results: Analysis revealed a significant U-shaped relationship between age-adjusted CHD rates and both TC and LDL-C. The ranges of TC and LDL-C with the lowest risk of CHD were 200 to 219 mg/dL and 120 to 139 mg/dL, respectively. As cholesterol concentrations declined and increased beyond these ranges, the risk of CHD increased. These U-shaped relationships remained significant after adjusting for age and other risk factors. Conclusion: The U-shaped associations between TC and LDL-C and CHD imply a complex relationship between lipids and CHD in late life. The results indicate that elevated lipid levels should continue to be treated in healthy elderly individuals, as they are in those who are younger, although pharmacologically lowering lipids to excessively low levels in the elderly may warrant further study, as does the contribution of subclinical frailty to the relationship of lipids to CHD risk. [source] Substrate incorporation patterns of bacterioplankton populations in stratified and mixed waters of a humic lakeENVIRONMENTAL MICROBIOLOGY, Issue 7 2009Ulrike Buck Summary Bacterial incorporation of glucose, leucine, acetate and 4-hydroxybenzoic acid (HBA) was investigated in an artificially divided humic lake (Grosse Fuchskuhle, Germany). Two basins with contrasting influx of allochthonous organic carbon were sampled during late summer stratification (oxic and anoxic layers) and after autumn mixing. High total and cell-specific incorporation rates were observed for glucose and HBA in stratified and mixed waters respectively, but only a small fraction of bacteria visibly incorporated HBA. The oxic layer of the more humic-rich basin featured a significantly lower fraction of glucose incorporating cells and substantially higher proportions of acetate assimilating bacteria. Niche differentiation was observed in two betaproteobacterial populations: cells affiliated with the Polynucleobacter C subcluster efficiently incorporated acetate but little glucose, whereas the opposite was found for members of the R-BT065 clade. By contrast, leucine incorporation was variable in both taxa. Considering the high concentrations and rapid photochemical generation of organic acids in humic waters our results may help to explain the success of the Polynucleobacter C lineage in such habitats. Specific substrate or habitat preferences were also present in three subgroups of the actinobacterial acI lineage: The numerically dominant clade in oxic waters (acI-840-1) was absent in the anoxic zone and did not incorporate acetate. A second group (acI-840-2) was found both in the epi- and hypolimnion, whereas the third one (acI-840-3) only occurred in anoxic waters. Altogether our results suggest a constitutive preference for some substrates versus an adaptive utilization of others in the studied microbial groups. [source] Quality Characteristics of Sea Bass Intensively Reared and from Lagoon as Affected by Growth Conditions and the Aquatic EnvironmentJOURNAL OF FOOD SCIENCE, Issue 2 2002E. Orban ABSTRACT: Sea bass (Dicentrarchus labrax) of commercial size free-living in the lagoon of Orbetello (Tuscany, Italy) and from intensive rearing were compared for proximate composition, essential and toxic metals, unsaponifiable lipids, and for the fatty acid profile of total, neutral, and polar lipids. Farmed sea bass had a total lipid content (10.57 ± 0.17g/100g) significantly higher (P , 0.001) than fish in the wild (1.78 ± 0.01 g/100g). Fish from either productive systems showed comparably high total polyunsaturated fatty acid levels and n-3/n-6 ratio values. Differences in the mineral content occurred among fish, particularly in the levels of mercury and selenium, significantly higher in those from the lagoon. [source] Separation of benzene and deuterated benzenes by reversed-phase and recycle liquid chromatography using monolithic capillary columnsJOURNAL OF SEPARATION SCIENCE, JSS, Issue 15-16 2004Lee Wah Lim Abstract An alternate pumping-recycle system utilizing a commercially available low dead-volume switching valve was developed for microcolumn LC. The recycle system had two separation columns, and the dead volume of the recycling lines was kept to a minimum by avoiding passage of the sample through the pump chamber, sample injector, and the normal path length of a conventional UV detector. The drawback of the high total back pressure caused by the second column that is placed after the detector was overcome by on-column detection, and this eliminated the need for a high pressure flow cell. The system was used for the separation of an authentic mixture of benzene, benzene-1,3,5-d3, and benzene-d6. Baseline separation was accomplished after six cycles and the calculated theoretical plate number for benzene was 230,000. It was observed that the theoretical plate number (N) increased linearly with increasing number of cycles, and the N per unit time increased with increasing inlet pressure. The separation conditions were optimized and the separation of benzene and benzene-d6 was accomplished within 75 min at 2.5 MPa inlet pressure. [source] Thermochemical Sulfate Reduction in the Tazhong District, Tarim Basin, Northeast China: Evidence from Formation Water and Natural Gas GeochemistryACTA GEOLOGICA SINICA (ENGLISH EDITION), Issue 2 2010Caifu XIANG Abstract: Systematic analyses of the formation water and natural gas geochemistry in the Central Uplift of the Tarim Basin (CUTB) show that gas invasion at the late stage is accompanied by an increase of the contents of H2S and CO2 in natural gas, by the forming of the high total dissolved solids formation water, by an increase of the content of HCO,3, relative to Cl,, by an increase of the 2nd family ions (Ca2+, Mg2+, Sr2+ and Ba2+) and by a decrease of the content of SO2,4, relative to Cl,. The above phenomena can be explained only by way of thermochemical sulfate reduction (TSR). TSR often occurs in the transition zone of oil and water and is often described in the following reaction formula: ,CH+CaSO4+H- 2O,H2S+CO2+CaCO3. (1) Dissolved SO2,4 in the formation water is consumed in the above reaction, when H2S and CO2 are generated, resulting in a decrease of SO2,4 in the formation water and an increase of both H2S and CO2 in the natural gas. If formation water exists, the generated CO2 will go on reacting with the carbonate to form bicarbonate, which can be dissolved in the formation water, thus resulting in the enrichment of Ca2+ and HCO,3. The above reaction can be described by the following equation: CO2+H2O+CaCO3,Ca2++2HCO,3. The stratigraphic temperatures of the Cambrian and lower Ordovician in CUTB exceeded 120°C, which is the minimum for TSR to occur. At the same time, dolomitization, which might be a direct result of TSR, has been found in both the Cambrian and the lower Ordovician. The above evidence indicates that TSR is in an active reaction, providing a novel way to reevaluate the exploration potentials of natural gas in this district. [source] | ||||||||||