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High Interest (high + interest)
Selected AbstractsWhen being disadvantaged grows into vengeance: The effects of asymmetry of interest and social rejection in social dilemmasEUROPEAN JOURNAL OF SOCIAL PSYCHOLOGY, Issue 4 2009Jeroen Stouten In public good dilemmas, group members often differ in the extent to which they benefit from provision of the public good (asymmetry of interest). In the current paper, we argue that people may readily accept such financial differences in interest when their social needs are met by being accepted by the others. When people are socially rejected, however, members having a low rather than a high interest in the public good may display negative emotional and retributive reactions. This reasoning was supported by the findings of a first experimental study in which we manipulated people's interest in the public good and social rejection. These effects were replicated in a second experimental study and it was further shown that this two-way interaction between social rejection and interest in the public good was moderated by people's social value orientation. The negative reactions to low interest (vs. high interest) in the public good when being socially rejected were especially prominent among group members with a proself orientation. Taken together, the current studies illustrate the importance of studying how financial and social needs interact to determine emotional and retributive actions in social dilemmas. Copyright © 2008 John Wiley & Sons, Ltd. [source] Rainfall-induced landslides and debris flowsHYDROLOGICAL PROCESSES, Issue 4 2008Giovanni B. Crosta Abstract In this preface we introduce the special issue on rainfall-induced landslides and debris flows. The topic is of high interest for many practical and scientific reasons. In fact, rainfall is the most relevant factor for the triggering of both shallow and deep-seated landslides, and rainfall analysis is the most frequently adopted approach for forecasting the occurrence of such phenomena. The six papers of the special issue cover most of the key issues relative to rainfall-induced landslides. Starting from the analysis of these contributions, we identify and discuss, in this paper, several main topics that deserve further research in the field of rainfall-induced landslide, such as the uncertainty of the data, the quality of geotechnical analysis, the validation of the models, and the applicability of results in the framework of natural hazards. Copyright © 2007 John Wiley & Sons, Ltd. [source] Application of the TLM technique to integrated optic component modellingINTERNATIONAL JOURNAL OF NUMERICAL MODELLING: ELECTRONIC NETWORKS, DEVICES AND FIELDS, Issue 2 2001O. Jacquin The TLM algorithm is of high interest to simulate new integrated optical devices as a ,photonic band gap' (PBG) structures. These components are realized with semiconductor material and constituted by a set of abrupt optical discontinuities. The electromagnetic behaviour of these structures does not allow the use of usual simulation methods of integrated optics. Indeed, their validity conditions are not satisfied. Then, we have to use unusual simulation method for integrated optics as TLM software which allows the visualization and understanding of the behaviour of electromagnetic field in the PBG structures. In this paper, the simulation results of different optical devices made from the TLM method are presented. Copyright © 2001 John Wiley & Sons, Ltd. [source] A new source of aging?JOURNAL OF COSMETIC DERMATOLOGY, Issue 2 2009Helen Knaggs MD Summary There has been a considerable increase in understanding how skin ages, along with significant progress toward the correction and prevention of the visible signs of aging. However, there are still many unknown factors regarding why we age , and why we all seem to age differently. An area of high interest is the biological or intrinsic processes that affect our appearance over time. This article describes a recent discovery of a membrane bound enzyme proven to be present in skin and increases its activity as biological age increases. The enzyme is located on the external surface of both fibroblast and keratinocytes, and generates free radicals. Therefore, as we age there appears to be a biological mechanism that further increases the production of free radicals. Additionally, there appears to be a relationship between activity of the enzyme and appearance. Data showed that subjects who look younger than their biological age had lower enzyme activity and conversely, subjects who looked older than their biological age had higher enzyme activity. Free radicals are believed to be a major contributing factor in the production of fine lines and wrinkles by destroying the collagen and elastin network keeping skin supple and firm. [source] Metabolomic fingerprinting of plant extracts,JOURNAL OF MASS SPECTROMETRY (INCORP BIOLOGICAL MASS SPECTROMETRY), Issue 12 2006L. Mattoli Abstract The standardization and quality control of plant extracts is an important topic, in particular, when such extracts are used for medicinal purposes. Consequently, the development of fast and effective analytical methods for metabolomic fingerprinting of plant extracts is of high interest. In this investigation, electrospray mass spectrometry (ESI-MS) and 1H NMR techniques were employed with further statistical analyses of the acquired data. The results showed that negative ion mode ESI-MS is particularly effective for characterization of plant extracts. Different samples of the same species appear well-clustered and separated from the other species. To verify the effectiveness of the method, two other batches of extracts from a species, in which the principal components were already identified (Cynara scolymus), were analyzed, and the components that were verified by the principal component analysis (PCA) were found to be within the region identified as characteristic of Cynara Scolymus extracts. The data from extracts of the other species were well separated from those pertaining to the species previously characterized. Only the case of a species that was strictly correlated from a botanical point of view, with extracts that were previously analyzed, showed overlapping. Copyright © 2006 John Wiley & Sons, Ltd. [source] The emerging role of epigenetic modifications and chromatin remodeling in spinal muscular atrophyJOURNAL OF NEUROCHEMISTRY, Issue 6 2009Sebastian Lunke Abstract As the leading genetic cause for infantile death, Spinal Muscular Atrophy (SMA) has been extensively studied since its first description in the early 1890s. Though today much is known about the cause of the disease, a cure or effective treatment is not currently available. Recently the short chain fatty acid valproic acid, a drug used for decades in the management of epilepsy and migraine therapy, has been shown to elevate the levels of the essential survival motor neuron protein in cultured cells. In SMA mice, valproic acid diminished the severity of the disease phenotype. This effect was linked to the ability of the short chain fatty acid to suppress histone deacetylase activity and activate gene transcription. Since then, the study of different histone deacetylase inhibitors and their epigenetic modifying capabilities has been of high interest in an attempt to find potential candidates for effective treatment of SMA. In this review, we summarize the current knowledge about use of histone deacetylase inhibitors in SMA as well as their proposed effects on chromatin structure and discuss further implications for possible treatments of SMA arising from research examining epigenetic change. [source] Fischer-Tropsch synthesis product grade optimization in a fluidized bed reactorAICHE JOURNAL, Issue 8 2006Fabiano A. N. Fernandes Abstract Fischer-Tropsch synthesis is an important chemical process for the production of liquid fuels and olefins. In recent years, the abundant availability of natural gas and the increasing demand of olefins, gasoline, diesel and waxes have led to a high interest in further developing this process. A mathematical model of a fluidized-bed reactor used for syngas polymerization was developed and the carbon monoxide polymerization was studied from a modeling point of view. Simulation results show that several parameters affect syngas conversion and carbon product distribution, such as operating pressure, superficial gas velocity, bed porosity, and syngas composition. Optimization of liquid hydrocarbon products was done and the best operating conditions for their production were found for an iron catalyst that produces hydrocarbon chains according to a dual mechanism theory. © 2006 American Institute of Chemical Engineers AIChE J, 2006 [source] Shotgun proteomic analysis of the microsomal fraction of eukaryotic cells using a two-dimensional reversed-phase×ion-pair reversed-phase HPLC setupJOURNAL OF SEPARATION SCIENCE, JSS, Issue 8 2009Martin Wörner Abstract A RP×IP-RP HPLC separation scheme was combined with on-line ESI-IT tandem MS or off-line MALDI tandem TOF MS and applied to the analysis of eukaryotic subcellular proteomes. Previous proteomic studies [1] were complemented by the approval of the approach to eukaryotic proteomes using the fission yeast Schizosaccharomyces pombe. The major focus was set to the analysis of primary human hepatocyte microsomes, representing a compartment of high interest due to its involvement in xenobiotic detoxification and cholesterol homeostasis. Of the 588 proteins identified from two donors, 24% are involved in cholesterol homeostasis or xenobiotic/lipid metabolism. Up to 50% of the identified proteins belong to the group of membrane proteins, difficult to investigate using gel-based proteomic approaches. We further demonstrated the reproducibility and comparability of the approach and reduced the amount of sample load by almost 70% with only minor loss of information about the proteins identified in the samples. The presented study clearly demonstrates the good applicability of the experimental setup to the analysis of subcellular proteomes including large membrane fractions, where only low amounts of sample material are available. [source] Analytical methodologies for quantification of ferulic acid and its oligomersJOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, Issue 9 2008Hélène Barberousse Abstract Ferulic acid (4-hydroxy-3-methoxycinnamic acid) is the most widespread hydroxycinnamic acid in the plant world, where it is a key molecule in cell wall architecture. Owing to its high antioxidant properties, ferulic acid shows large potential applications in food industry as well as in the health and cosmetic markets. There is thus a high interest in extracting this high-value compound from waste materials of the agricultural industry, which requires the selection of an appropriate quantification method. This paper therefore gives an overview of analytical methodologies developed over past decades for quantification of ferulic acid and its oligomers. Copyright © 2008 Society of Chemical Industry [source] Synthesis and thermal degradation kinetics of cellulose estersPOLYMERS FOR ADVANCED TECHNOLOGIES, Issue 7 2003M. Sairam Abstract Polymers that are biodegradable currently achieve high interest in material science since they offer reductions of landfill space during waste management as well as new end-user benefits in various fields of applications. In this work, cellulose esters such as cellulose benzoate, cellulose succinate and cellulose cinnamate were prepared using dimethylaminopyridine along with dimethylaminopyridine-p-toluene sulfonic acid catalyst. Films of cellulose esters were cast from solution. Cellulose esters were characterized by spectral methods such as infrared, nuclear magnetic resonance, thermal method such as thermogravimetric analysis. Various methods of kinetic analysis were compared in the case of thermal degradation of the cellulose and cellulose esters. Copyright© 2003 John Wiley & Sons, Ltd. [source] Spatial representation of odorant structure in the moth antennal lobe: A study of structure,response relationships at low dosesTHE JOURNAL OF COMPARATIVE NEUROLOGY, Issue 1 2003Jocelijn Meijerink Abstract How odorant structure and concentration are spatially represented within the primary olfactory integration center, the antennal lobe (AL) or olfactory bulb (OB) in invertebrates and vertebrates, respectively, is currently a topic of high interest. Here, we show the spatial representation of odorant structure in the antennal lobe of the moth Spodoptera littoralis by imaging calcium activity evoked by straight chain aliphatic alcohols and aldehydes at low doses. Activity patterns of a given odor were most similar to compounds with the same functional group, differing in chain length by only one carbon atom. A chain length dependency was present as the most activated glomerulus in the lobe shifted from a medial to a lateral position with increasing chain length of the molecule. Statistical analysis revealed that in both classes of chemicals the chain length of the molecule was represented in a similar way. No topographically fixed domains were observed for any of the classes. However, activity patterns evoked by lower chain length molecules were spatially more distinct than patterns evoked by higher chain length molecules. The number of activated glomeruli for both classes of chemicals increased with increasing chain length to reach a maximum at eight or nine C atoms followed by a decrease as the chain length further increased. J. Comp. Neurol. 467:11,21, 2003. © 2003 Wiley-Liss, Inc. [source] | ||||||||||||||||