Health Institutes (health + institute)

Distribution by Scientific Domains


Selected Abstracts


Chlamydia pneumoniae and luminal narrowing after coronary angioplasty

JOURNAL OF INTERNAL MEDICINE, Issue 1 2001
K. J. Mattila
Mattila KJ, Juvonen JT, Kotamäki MK, Saikku PA (Helsinki University Hospital, Helsinki; Kainuu Central Hospital, Kajaani, and National Public Health Institute, Oulu, Finland). Chlamydia pneumoniae and luminal narrowing after coronary angioplasty. J Intern Med 2001; 250: 67,71. Objectives.,Numerous studies have linked Chlamydia pneumoniae with atherosclerotic vessel disease and a trend for an association of the bacteria with restenosis after percutaneous transluminae coronary angioplasty (PTCA) has also been observed. The aim of this study was to assess the role of Chlamydia pneumoniae in the luminal narrowing taking place after PTCA. Design.,A noninterventional 6-month follow-up study. Setting.,A university hospital. Subjects.,A total of 122 patients with angiographically proven coronary heart disease (CHD) referred for PTCA. Interventions.,None. Main outcome measures.,The degree of luminal narrowing in the coronary arteries following coronary angioplasty. Results.,The levels of C. pneumoniae antibodies (IgG, IgA and IgM classes) and immune complexes were not associated with luminal narrowing after PTCA in multivariate analyses whilst smoking, plasma endothelin levels and diabetes were. The serologic parameters did not change during the follow up either. Conclusions.,These results do not support a role for C. pneumoniae in luminal narrowing following PTCA. [source]


Chlamydia pneumoniae in atherosclerosis

JOURNAL OF INTERNAL MEDICINE, Issue 3 2000
P. Saikku
Abstract. Saikku P (National Public Health Institute, Oulu, Finland). Chlamydia pneumoniae in atherosclerosis (Minisymposium). J Intern Med 2000; 247: 391,396. Chlamydia pneumoniae is currently the infectious agent most often associated with the inflammation found in atherosclerosis. The seroepidemiological association and the actual presence of pathogen in lesions has been confirmed in numerous studies, in which technical difficulties seem to be the only limitation. Besides animal experiments and intervention trials, we need information of possible pathogenic mechanisms. Recently, several studies have suggested mechanisms by which C. pneumoniae infection could participate in the development of atherosclerosis. [source]


Social Influence in Personally Relevant Contexts: The Respect Attributed to the Source as a Factor Increasing Smokers' Intention to Quit Smoking,

JOURNAL OF APPLIED SOCIAL PSYCHOLOGY, Issue 9 2003
Federica Invernizzi
The study examined the effects of the status of the source in personally relevant persuasion contexts. Smokers (N= 117) with either weak or strong identity as smokers were exposed to an anti-smoking message, targeting either the tobacco industry or smokers, and attributed either to a health institute or a neighborhood association. The main dependent variable was the change in intention to quit smoking. As expected, the neighborhood association was considered more respectful of the freedom of choice of the target than was the health institute. In high personal relevance conditions (i.e., participants with strong identities as smokers and message explicitly targeting smokers), smokers strengthened their intention to quit smoking when the source was the neighborhood association, but decreased it when the source was the health institute. Implications for health campaign implementation are discussed. [source]


Psychological mindedness in relation to personality and coping in a sample of young adult psychiatric patients

JOURNAL OF CLINICAL PSYCHOLOGY, Issue 1 2010
Ivan Nyklí
Abstract Psychological mindedness (PM) is a relevant but rarely studied construct in clinical psychology. The aim was to examine the relationships among PM, personality, and coping in young adults with psychological difficulties. Sixty-three young women and 32 young men who were admitted for intake at a Dutch mental health institute completed relevant questionnaires. PM showed positive associations with the putatively adaptive personality characteristics of extraversion, openness, agreeableness, and conscientiousness and a negative correlation with neuroticism. In addition, PM was associated with problem-focused coping independently of the effect of personality characteristics. PM seems to be related to adaptive person characteristics in young adults with psychological difficulties. Longitudinal studies are needed to examine the issue of causality. © 2009 Wiley Periodicals, Inc. J Clin Psychol 66:1,12, 2010. [source]


Systems for accreditation in blood transfusion services

ISBT SCIENCE SERIES: THE INTERNATIONAL JOURNAL OF INTRACELLULAR TRANSPORT, Issue 1 2009
S. Hindawi
Accreditation is a non-governmental, voluntary process that evaluates institutions, agencies, and educational programs. It is defined as the process whereby an agency or association grants public recognition to Institutes or Blood Banks for having met certain established standards as determined through initial and periodic evaluations that usually involve submitting a self-evaluation report, site inspection by a team of experts, and evaluation by an independent board or commission. To be accredited Institution and or Blood Transfusion Services should establish and maintain quality systems involving all activities that determine the quality policy objectives & responsibilities taking into account the principles of good manufacturing practice (GMP). There are many Established systems for accreditation which can help any institution to know its strengths, weaknesses and opportunities through an informed review process. Any assessment and subsequent accreditation is made with reference to a set of standards so that the standing of an institution can be compared with that of other similar institutions. In summery the accreditation is a continuous process for improvement of quality and safety of participating institutes or facilities and we should encourage all health institutes to be involved in one or another system for accreditation. There is a need for a local or regional accreditation system for health institutes especially for blood transfusion services to help in the development and improvement of the quality of their services. [source]


Professional Development of Nursing in Saudi Arabia

JOURNAL OF NURSING SCHOLARSHIP, Issue 3 2001
Gail Tumulty
Purpose: To describe the development of nursing in Saudi Arabia and to recommend further directions for development of professional nursing in that country. Organizing Construct: A comprehensive needs assessment was performed in 1996 by an onsite consultant to: (a) evaluate the existing nursing system at the ministry, regional, and hospital levels, (b) describe the functional interrelationships of a nursing division within the Ministry of Health, and (c) prepare a work plan outlining the program elements that a nursing division could address to foster high-quality health care in the public sector. Methods: The needs assessment was conducted through direct observation, interviews, and review of existing documents in the Ministry of Health and representative hospitals, health centers, and health institutes. Data were collected about six factors as they pertained to the Ministry of Health Nursing Services: (a) key organizational and managerial activities, (b) the external environment, (c) the social system, (d) employees, (e) nursing services and research, and (f) formal organizational arrangements. Findings and Conclusions: The data showed a young country and an equally young nursing profession struggling to meet the needs of a growing population. The highest priority for the advancement of nursing in Saudi Arabia is the creation of a kingdom-wide system of nurse regulation. Pressing needs include regulation of professional standards, licensure of all nurses practicing in the Kingdom, accreditation of educational programs, and formation of a national nurses association. [source]


Quality of different chondroitin sulfate preparations in relation to their therapeutic activity

JOURNAL OF PHARMACY AND PHARMACOLOGY: AN INTERNATI ONAL JOURNAL OF PHARMACEUTICAL SCIENCE, Issue 10 2009
Prof. Nicola Volpi
Abstract Objectives Chondroitin sulfate is currently recommended by the European League Against Rheumatism (EULAR) as a SYSADOA (symptomatic slow acting drug for osteoarthritis) in Europe in the treatment of knee and hand osteoarthritis based on research evidence and meta-analysis of numerous clinical studies. Furthermore, recent clinical trials demonstrated its possible structure-modifying effects. Chondroitin sulfate, alone or in combination with glucosamine or other ingredients, is also utilized as a nutraceutical in dietary supplements in Europe and the USA. However, it is derived from animal sources by extraction and purification processes. As a consequence, source material, manufacturing processes, the presence of contaminants and many other factors contribute to the overall biological and pharmacological actions of these agents. We aim to review the quality control of chondroitin sulfate in pharmaceutical-grade preparations and nutraceuticals. Key findings Pharmaceutical-grade formulations of chondroitin sulfate are of high and standardized quality, purity and properties, due to the stricter regulations to which this drug is subjected by local national health institutes as regards production and characteristics. On the contrary, as several published studies available in literature indicate, the chondroitin sulfate quality of several nutraceuticals is poor. Additionally, there are no definite regulations governing the origin of the ingredients in these nutraceuticals and the origin of the ingredients in natural products is the most important factor ensuring quality, and thus safety and efficacy, in particular for chondroitin sulfate, due to its extraction from different sources. Conclusions Due to the poor chondroitin sulfate quality of some nutraceuticals, we conclude that stricter regulations regarding their quality control should be introduced to guarantee the manufacture of high quality products for nutraceutical utilization and to protect customers from low-quality, ineffective and potentially dangerous products. There is a need for specific and accurate analytical procedures, which should be enforced to confirm purity and label claims both for raw materials and finished chondroitin sulfate products, and also to govern the origin of ingredients. Until these stricter regulations are in place, then it is strongly recommended that pharmaceutical-grade chondroitin sulfate is used rather than food supplements. [source]