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Helicobacter Pylori Seropositivity (helicobacter + pylori_seropositivity)

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Medical Sciences	100%

Selected Abstracts

Tooth Loss and Helicobacter pylori Seropositivity: the Newcastle Thousand Families Cohort Study at Age 49,51 Years

HELICOBACTER, Issue 1 2005
Mark S. Pearce
ABSTRACT Background.,Helicobacter pylori, one of the commonest chronic bacterial infections of humankind, is an important risk factor for gastric carcinoma. It has also been suggested to be present in dental plaque. This study investigated the potential link between the number of teeth lost and H. pylori seropositivity at age 50 years. Methods.,H. pylori seropositivity at age 50 years was investigated among 334 individuals born in Newcastle upon Tyne, United Kingdom, in May and June 1947 and related to the number of teeth lost, after adjusting for socioeconomic status. Results., The unadjusted risk of being seropositive for H. pylori increased with increasing number of teeth lost (odds ratio per tooth 1.03, 95% confidence interval 1.01,1.06, p = .019). However, after adjustment for socioeconomic status at birth and at age 50 years, the relationship was no longer significant (p = .36). Conclusions., Our results, obtained using prospectively collected data, suggest that any relationship between poor oral health and seropositivity to H. pylori may be due to both tooth loss and H. pylori colonization being associated with socioeconomic status and related factors. [source]

Helicobacter pylori Seropositivity among 963 Japanese Brazilians According to Sex, Age, Generation, and Lifestyle Factors

CANCER SCIENCE, Issue 11 2001
Lucy S. Ito
Seropositivity of anti,Helicobacter pylori antibody (HP+) was examined among Japanese Brazilians. The study was announced through 18 Japanese community culture associations in São Paulo, Curitiba, Mogi das Cruzes, and Mirandopolis in 2001. Among 969 participants, 963 individuals aged 33,69 years were analyzed. The overall HP+% was 48.1% (95% confidence interval, 44.9,51.3%). There was no difference in HP+% between 399 males and 564 females (49.6% and 47.0%, respectively). The HP+% increased with age; 35.3% for those aged 33,39 years, 46.2% for those aged 40,49 years, 46.5% for those aged 50,59 years, and 56.9% for those aged 60,69 years, but no differences were observed among the generations (Issei, Nisei, and Sansei) for each 10,year age group. Mogi das Cruzes, a rural area, showed a higher HP+%. Length of education was inversely associated with the positivity; the odds ratio (OR) relative to those with eight years or less of schooling was 0.61 (0.42,0.89) for those with 12 years or more. The associations with smoking and alcohol drinking were not significant. Fruit intake was associated with the HP+%; the OR relative to everyday intake was 1.38 (1.05,1.83) for less frequent intake, while intake frequencies of green tea, miso soup, and pickled vegetables (tsukemono) were not. Multivariate analysis including sex, 10,year age group, residence, education, and fruit intake showed that all factors except sex were significant. This is the largest study of HP infection among Japanese Brazilians, and the results indicated a similar pattern of age,specific infection rate to that for Japanese in Japan. [source]

Epidemiology of Helicobacter pylori infection in children: A serologic study of the Kyushu region in Japan

PEDIATRICS INTERNATIONAL, Issue 1 2001
Yasuhiro Yamashita
Background: The prevalence of Helicobacter pylori infection in children varies as a function of socioeconomic development, with low rates in developed countries and high rates in developing countries. The prevalence of H. pylori infection in Japanese children is unknown. Methods: The present study examined the effect of living conditions on the prevalence of H. pylori infection in children. We determined the prevalence of H. pylori infection in healthy children of the Kyushu region in Japan and compared it with the prevalence in institutionalized children with severe neurologic illness. Serum concentrations of anti- H. pylori IgG antibody were measured by an enzyme-linked immunosorbent assay in 336 healthy children and 56 patients with severe neurologic impairment. An antibody concentration >50 units/mL was taken as evidence of infection. Results: The prevalence of H. pylori seropositivity in healthy children increased with age (P<0.0001) and was 29% in children 15,19 years of age. This value is slightly higher than prevalences reported in developed countries (5,15%), but is lower than in developing countries (30,60%). Seropositivity did not vary with respect to gender, water supply or location of housing. Helicobacter pylori seropositivity was more prevalent among institutionalized children aged 5,19 years than their healthy counterparts (P<0.005). Conclusions: The intermediate prevalence of H. pylori seropositivity in healthy children between that measured in developed and developing countries is consistent with the socioeconomic ,westernization' of Japan. [source]

Helicobacter pylori infection in children: population-based age-specific prevalence and risk factors in a developing country

ACTA PAEDIATRICA, Issue 2 2010
W Jafri
Abstract Aim:, We estimated the prevalence, age of acquisition and risk factors for Helicobacter pylori (H. pylori) seroprevalence in children aged 1,15 years. Methods:, Exposure was assessed using ELISA. Parents responded to a questionnaire regarding number of individuals sharing house, rooms, water source, latrines, housing and assessment of socioeconomic status (SES) by Hollingshead Index. Results:, Serum of 1976 children was tested. Helicobacter pylori seropositivity in children aged 11,15 years was 53.5% (OR: 2.0, 95% CI: 1.58,2.5). It increased with moderate crowding index (CRI) of 2,4 to 45.9% (OR: 1.23, 95% CI: 0.92,1.63) and to 51.2% with CRI >4 (OR: 1.52, 95% CI: 1.12,2.06). In middle SES, seropositivity was 50.5% (331/655) (OR: 1.7, 95% CI: 1.29,2.35), whereas in lower SES, it was 47.1% (500/1062) (OR: 1.5, 95% CI: 1.1,2.0). Multivariate analysis showed that Helicobacter pylori seroprevalence was high in children aged 6,10 and 11,15 years (OR: 1.5, 95% CI: 1.2,1.9 and OR: 1.9, 95% CI: 1.56,2.47 respectively), in lower-middle SES (OR: 1.6, 95% CI: 1.2,2.1 and OR: 1.5, 95% CI: 1.10,2.0 respectively) and in uneducated fathers (OR: 1.58, 95% CI: 1.27,1.95). Conclusion:,Helicobacter pylori seropositivity increases with age, in low-middle SES and is related to father's educational status. Reducing H. pylori seroprevalence will require improvement in sanitary conditions and educational status of the population. [source]