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Hard X-ray Microscope (hard + x-ray_microscope)

Distribution by Scientific Domains
Medical Sciences75%

Selected Abstracts

A study of the human hair structure with a Zernike phase contrast X-ray microscope

JOURNAL OF MICROSCOPY, Issue 2 2007
HWA SHIK YOUN
Summary We have observed the internal structure of human hair shafts with a transmission Zernike phase contrast hard X-ray microscope. Due to the high spatial resolution and the high contrast of the microscope, we could image scales, macrofibrils, medulla and melanin without staining. The structure of a black hair shaft is compared with that of a white one. [source]

Zernike-type phase-contrast hard X-ray microscope with a zone plate at the Photon Factory

JOURNAL OF SYNCHROTRON RADIATION, Issue 3 2002
Hiroki Yokosuka
A Zernike-type phase-contrast X-ray microscope with a zone plate and a phase plate was constructed at the Photon Factory BL3C2. Parallel monochromatic X-rays of 8.97,keV were incident on a specimen and a direct beam transmitted through the specimen was focused on the back focal plane of the zone plate, where an aluminium phase plate was placed. Tantalum line patterns as fine as 0.3,µm could be imaged. Phase-contrast images of polypropylene wires and polystyrene latex beads were obtained, which showed better contrast than that of their bright field images. [source]

X-ray imaging of various biological samples using a phase-contrast hard X-ray microscope

MICROSCOPY RESEARCH AND TECHNIQUE, Issue 9 2008
Guk Bae Kim
Abstract In this study, we visualized the internal structures of various bio-samples and found the optimum conditions of test samples for the 7 keV hard X-ray microscope of the Pohang light source. From the captured X-ray images, we could observe the intercellular and intracellular structures of dehydrated human cells and mouse tumor tissues without using any staining materials in a spatial resolution better than 100 nm. The metastasized lung tissue, which was several tens of micrometers in thickness, was found to be very well suited to this hard X-ray microscope system, because it is nearly impossible to observe such a nontransparent and thick sample with a high spatial resolution better than 100 nm using any microscopes such as a soft X-ray microscope, an optical microscope, or an electron microscope. Microsc. Res. Tech., 2008. © 2008 Wiley-Liss, Inc. [source]