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Group Sample (group + sample)

Distribution by Scientific Domains

Medical Sciences	50%

Selected Abstracts

Parent-Identified Barriers to Pediatric Health Care: A Process-Oriented Model

HEALTH SERVICES RESEARCH, Issue 1 2006
Elisa J. Sobo
Objective. To further understand barriers to care as experienced by health care consumers, and to demonstrate the importance of conjoining qualitative and quantitative health services research. Data Sources. Transcripts from focus groups conducted in San Diego with English- and Spanish-speaking parents of children with special health care needs. Study Design. Participants were asked about the barriers to care they had experienced or perceived, and their strategies for overcoming these barriers. Using elementary anthropological discourse analysis techniques, a process-based conceptual model of the parent experience was devised. Principal Findings. The analysis revealed a parent-motivated model of barriers to care that enriched our understanding of quantitative findings regarding the population from which the focus group sample was drawn. Parent-identified barriers were grouped into the following six temporally and spatially sequenced categories: necessary skills and prerequisites for gaining access to the system; realizing access once it is gained; front office experiences; interactions with physicians; system arbitrariness and fragmentation; outcomes that affect future interaction with the system. Key to the successful navigation of the system was parents' functional biomedical acculturation; this construct likens the biomedical health services system to a cultural system within which all parents/patients must learn to function competently. Conclusions. Qualitative analysis of focus group data enabled a deeper understanding of barriers to care,one that went beyond the traditional association of marker variables with poor outcomes ("what") to reveal an understanding of the processes by which parents experience the health care system ("how,""why") and by which disparities may arise. Development of such process-oriented models furthers the provision of patient-centered care and the creation of interventions, programs, and curricula to enhance such care. Qualitative discourse analysis, for example using this project's widely applicable protocol for generating experientially based models, can enhance our knowledge of the parent/patient experience and aid in the development of more powerful conceptualizations of key health care constructs. [source]

Evolution in the discs and bulges of group galaxies since z= 0.4

MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY, Issue 4 2008
Sean L. McGee
ABSTRACT We present quantitative morphology measurements of a sample of optically selected group galaxies at 0.3 < z < 0.55 using the Hubble Space Telescope (HST) Advanced Camera for Surveys (ACS) and the gim2d surface brightness fitting software package. The group sample is derived from the Canadian Network for Observational Cosmology Field Galaxy Redshift Survey (CNOC2) and follow-up Magellan spectroscopy. We compare these measurements to a similarly selected group sample from the Millennium Galaxy Catalogue (MGC) at 0.05 < z < 0.12. We find that, at both epochs, the group and field fractional bulge luminosity (B/T) distributions differ significantly, with the dominant difference being a deficit of disc-dominated (B/T < 0.2) galaxies in the group samples. At fixed luminosity, z= 0.4 groups have ,5.5 ± 2 per cent fewer disc-dominated galaxies than the field, while by z= 0.1 this difference has increased to ,19 ± 6 per cent. Despite the morphological evolution we see no evidence that the group environment is actively perturbing or otherwise affecting the entire existing disc population. At both redshifts, the discs of group galaxies have similar scaling relations and show similar median asymmetries as the discs of field galaxies. We do find evidence that the fraction of highly asymmetric, bulge-dominated galaxies is 6 ± 3 per cent higher in groups than in the field, suggesting there may be enhanced merging in group environments. We replicate our group samples at z= 0.4 and 0 using the semi-analytic galaxy catalogues of Bower et al. This model accurately reproduces the B/T distributions of the group and field at z= 0.1. However, the model does not reproduce our finding that the deficit of discs in groups has increased significantly since z= 0.4. [source]

Surface-enhanced laser desorption/ionization-time of flight-mass spectrometry (SELDI-TOF-MS): A new proteomic urinary test for patients with urolithiasis

JOURNAL OF CLINICAL LABORATORY ANALYSIS, Issue 3 2004
Peter A. Cadieux
Abstract SELDI-TOF-MS is a highly sensitive protein-analysis tool capable of detecting minute protein profile differences between biological samples. As proteins have been associated with urinary tract calculi, protein-based urinalysis may offer insights into their diagnosis. The purpose of this study was to evaluate SELDI-TOF-MS as a potential method for identifying urinary biomarkers of urolithiasis. Midstream sterile urine samples were obtained from 25 male patients with a confirmed diagnosis of urolithiasis (test group) and 25 male subjects with no known history of the disease (controls). Urinary levels of oxalate, total protein, albumin, and osteopontin were determined. Protein profiles were generated using SELDI-TOF-MS. SELDI-TOF-MS profiling revealed a relationship between protein peak intensities at 67 and 24 kDa that differed between the two groups. The ratio of p67:p24 was found to be less than 1.0 in all of the control samples (mean 0.26), while 18 out of 25 (72%) of the test group samples displayed a ratio greater than 1.0 (total group mean 4.75, P<0.001). Albumin, total protein, and oxalate levels were higher in the test group than the controls. Although SELDI-TOF-MS is not yet in widespread use in hospital and diagnostic laboratories, this system represents a promising new method for rapidly identifying patients with urolithiasis. J. Clin. Lab. Anal. 18:170,175, 2004. © 2004 Wiley-Liss, Inc. [source]