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Greater Contribution (greater + contribution)
Selected AbstractsExploring the Frontier of Livelihoods ResearchDEVELOPMENT AND CHANGE, Issue 1 2005Leo De Haan This article discusses the value of livelihoods studies and examines the obstacles which have prevented it from making a greater contribution to understanding the lives of poor people over the past decade. After examining the roots of the livelihoods approach, two major challenges are explored: the conceptualization of the problem of access, and how to achieve a better understanding of the mutual link between livelihood opportunities and decision-making. The article concludes that access to livelihood opportunities is governed by social relations, institutions and organizations, and that power is an important (and sometimes overlooked) explanatory variable. In discussing the issue of access to livelihood opportunities, the authors note the occurrence of both strategic and unintentional behaviour and the importance of structural factors; they discuss concepts of styles and pathways, which try to cater for structural components and regularities; and they propose livelihood trajectories as an appropriate methodology for examining these issues. In this way, the article also sets the agenda for future livelihoods research. [source] Congener-specific toxicokinetics of polychlorinated dibenzo- p -dioxins, polychlorinated dibenzofurans, and coplanar polychlorinated biphenyls in black-eared kites (Milvus migrans): Cytochrome P4501A,dependent hepatic sequestrationENVIRONMENTAL TOXICOLOGY & CHEMISTRY, Issue 4 2006Akira Kubota Abstract Concentrations of dioxins and related compounds (DRCs), such as polychlorinated dibenzo- p -dioxins (PCDDs), polychlorinated dibenzofurans (PCDFs), and coplanar polychlorinated biphenyls (Co-PCBs), were determined in black-eared kites (BEKs; Milvus migrans) collected from the Kanto district in Japan. Total 2,3,7,8-tetra-CDD toxic equivalents (TEQs) were in the range of 99 to 3,800 pg/g lipid weight in the liver and 42 to 760 pg/g lipid weight in the pectoral muscle. Three congeners, including PCB 126, 2,3,4,7,8-penta-CDF, and 1,2,3,7,8-penta-CDD, made a greater contribution to total TEQs in both tissues. Levels of ethoxy-resorufin- O -deethylase activity and a cross-reactive protein with anti-rat cytochrome P4501A (CYP1A) polyclonal antibodies showed no significant correlation with hepatic TEQs. This may be attributed to low sensitivity and insufficient TEQ levels to cause CYP1A induction, high metabolic potential of a series of congeners, and influence of CYP1A inducers other than DRCs. Most of the PCDD/Fs and non- ortho Co-PCBs exhibited a total TEQ- and CYP1A-dependent increase in the liver to muscle concentration ratios, implying their concentration-dependent hepatic sequestration in which CYP1A was involved. Comparison of the toxicokinetics in avian species revealed that BEKs possibly have higher potentials than common cormorants for metabolizing and sequestering certain congeners in the liver in terms of hepatic concentration profiles and liver:muscle concentration ratios, respectively. These results clearly indicate that the toxicokinetics of DRCs is congener-, tissue-, and species-specific as well as concentration-dependent. Therefore, CYP1A expression is one of the critical factors that determine the toxicokinetics in wild avian species. [source] Individual Differences in the Contribution of Maternal Soothing to Infant Distress ReductionINFANCY, Issue 3 2007Laudan B. Jahromi This study investigates individual differences in the contribution of specific maternal regulatory behaviors to the mother-infant dyad's regulation of infant distress response. Additionally, we examined the stability of infants' stress responses and the stability of specific maternal soothing behaviors. The sample included 128 mother-infant dyads that were observed during an inoculation at 2 and 6 months. The average intensity of infant cry response showed modest stability across age only before controlling for the infant's general state of irritability, and the duration of crying was not stable. Of the 8 specific maternal regulatory behaviors studied, affection, touching, and vocalizing showed the strongest stability across infant age. Finally, an index of the contingency between maternal soothing and infant cry reduction at 2 months predicted shorter cry duration but not cry intensity at 6 months. The results of this study indicate that infants whose mothers showed a greater contribution to reducing their distress at 2 months showed a shorter duration of crying 4 months later. This suggests a possible longitudinal influence of maternal regulation on infants' distress responses. [source] Comparison of the contractile properties, oxidative capacities and fibre type profiles of the voluntary sphincters of continence in the ratJOURNAL OF ANATOMY, Issue 3 2010Maria Buffini Abstract The external urethral sphincter (EUS) and external anal sphincter (EAS) are the principal voluntary striated muscles that sustain continence of urine and faeces. In light of their common embryological origin, shared tonic sphincteric action and synchronized electrical activity in vivo, it was expected that they would exhibit similar physiological and structural properties. However, the findings of this study using paired observations of both sphincters isolated from the rat show clearly that this is not the case. The anal sphincter is much more fatigable than the urethral sphincter. On completion of a fatigue protocol, the amplitude of the last twitch of the EAS had declined to 42 ± 3% of the first twitch, whereas the last twitch of the EUS was almost identical to that of the first (95 ± 3%). Immunocytochemical detection of myosin heavy-chain isoforms showed that this difference was not due to the presence of more slow-twitch oxidative type 1 fibres in the EUS compared with the EAS (areal densities 4 ± 1% and 5 ± 1%, respectively; P = 0.35). In addition, the fatigue difference was not explained by a greater contribution to force production by fast oxidative type 2A fibres in the urethral sphincter. In fact, the anal sphincter contained a higher areal density of type 2A fibres (56 ± 5% vs. 37 ± 4% in the EUS, P = 0.017). The higher oxidative capacity of the EUS, measured histochemically, explained its fatigue resistance. These results were surprising because the fatigue-resistant urethral muscle exhibited faster single-twitch contraction times compared with the anal sphincter (56 ± 0.87 ms vs. 72.5 ± 1.16 ms, P < 0.001). Neither sphincter expressed the type 2X myosin isoform but the fast-twitch isoform type 2B was found exclusively in the EUS (areal density 16 ± 2%). The type 2B fibres of the EUS were small (diameter 19.5 ± 0.4 ,m) in comparison to typical type 2B fibres of other muscles. As a whole the EUS is a more oxidative than glycolytic muscle. In conclusion, analysis of the twitch mechanics and fatigue of two sphincters showed that the EUS contained more fatigue-resistant muscle fibres compared with the EAS. [source] Influence of selected factors on the dietary compositions of three targeted and co-occurring temperate species of reef fishes: implications for food partitioningJOURNAL OF FISH BIOLOGY, Issue 6 2010M. E. Platell The dietary compositions of three medium to large targeted fish species, which co-occur over reefs in temperate waters of south-western Australia, were determined. These data were then used to ascertain statistically the extent to which body size, season and habitat influence the diets of these species and the degree to which food resources were partitioned among and within those species, and thus reduced the potential of interspecific and intraspecific competition. On the west coast, Bodianus frenchii (Labridae) and Epinephelides armatus (Serranidae) spent their whole life over prominent limestone reefs, as did Glaucosoma hebraicum (Glaucosomatidae) in all but juvenile life, when it lived over low-relief, limestone substrata. The dietary composition of each species changed with increasing body size, which, in G. hebraicum, was particularly pronounced at c. 300 mm total length (LT) and therefore at the size when this species shifts habitat. When the three species co-occurred over the same reefs, their dietary compositions were significantly different, with that of B. frenchii being by far the most discrete, reflecting a far greater contribution by sedentary taxa. Thus, the diet of B. frenchii was distinguished from those of the other two species in containing substantial volumes of bivalve and gastropod molluscs and echinoid echinoderms and essentially no teleosts. Although the diets of G. hebraicum and particularly E. armatus were dominated by teleosts, and especially for larger individuals, the former species ingested greater volumes of cephalopods and small crustaceans. The pointed jaws of B. frenchii, with their forwardly directed and interlocking anterior incisors, are ideally adapted for biting and retaining their invertebrate prey, which are attached to or reside within reef crevices. In contrast, the mouths of G. hebraicum and E. armatus are broader and rounder and contain numerous small, slender and inward-pointing teeth. These teeth, in conjunction with prominent backward-curved canines in E. armatus, facilitate the capture and retention of fish prey. Observations in situ indicate that G. hebraicum is a suction feeder, while E. armatus is predominantly a ram feeder. Although reef environments on the west and south coasts differ, the diet of B. frenchii on these coasts differed only slightly. Interspecific differences in diet, combined with size-related changes in dietary compositions and the occupation of different habitats by juvenile and adult G. hebraicum, reduce the potential for competition for food resources among and within B. frenchii, G. hebraicum and E. armatus and thus helps facilitate the coexistence of these species which historically have been abundant over reefs in south-western Australia. [source] SOURCE ROCK EVALUATION AND GEOCHEMISTRY OF CONDENSATES AND NATURAL GASES, OFFSHORE NILE DELTA, EGYPTJOURNAL OF PETROLEUM GEOLOGY, Issue 2 2003L. M. Sharaf Geochemical analyses of mudstones from wells in the NE offshore Nile Delta suggest that the Early Miocene Qantara Formation has "good" potential to generate hydrocarbons at the studied locations. Its generating capability and oil-proneness increase northwards, towards areas where better organic-matter preservation and a greater contribution from marine source material can be expected. By contrast, the Middle Miocene Sidi Salem Formation has "poor to fair" potential to generate mixed gas and oil, while the overlying Wakar and Kafr El Sheikh Formations have "poor" capability to generate gas with minor oil. Based on pyrolysis Tmax and thermal alteration index assessments, the Wakar and Kafr El Sheikh Formations are immature in the study area. The Sidi Salem and Qantara Formations are immature in the southern part of the study area, but are within the oil window in the north, around well Temsah-4. Biomarker distributions based on GC-MS analyses of two condensate samples from the Wakar and Sidi Salem Formations indicate that hydrocarbons are derived from siliciclastic source rocks containing significant terrestrial material and limited marine organic matter. The condensates were generated during early maturation of Type III kerogen from deeper and more mature source rocks than those encountered in the drilled wells. Geochemical and isotopic data from natural gas produced from the Kafr El Sheikh Formation suggest mixed biogenic and thermogenic sources. [source] Content specificity: is it the full story?MEDICAL EDUCATION, Issue 6 2008Statistical modelling of a clinical skills examination Objective, This study sought to determine the relative contributions made by transferable skills and content-specific skills to Year 2 medical student performance in a clinical skills examination. Methods, Correlated trait-correlated method models were constructed to describe the performance of 2 year groups of students in examinations held in the summers of 2004 and 2005 at Peninsula Medical School in the UK. The transferable skills components of the models were then removed to indicate the contribution made to the fit of the models to the data. Results, Although content-specific skills made the greater contribution to the 2 models of student performance (accounting for averages of 54% and 43% of the variance, respectively), transferable skills did make an important but smaller contribution (averages of 13% and 16%, respectively). When the transferable skills components of the models were removed, the fit was not as good. Conclusions, Both content-specific skills and transferable skills contributed to performance in the clinical skills examination. This challenges current thinking and has important implications, not just for those involved in clinical skills examinations, but for all medical educators. [source] M2 mediated contractions of human bladder from organ donors is associated with an increase in urothelial muscarinic receptors,NEUROUROLOGY AND URODYNAMICS, Issue 1 2007Alan S. Braverman Abstract Aims Previous studies have shown increased density of M2 receptors in hypertrophied rat bladders that possess an M2 contractile phenotype. The aim of the current study is to determine whether human bladders with an M2 contractile phenotype also have a greater density of bladder M2 receptors. Materials and Methods Human bladders were obtained from 24 different organ transplant donors. Darifenacin and methoctramine affinity was determined by the rightward shift of cumulative carbachol concentration contractile response curves for each bladder. Radioligand binding and immunoprecipitation was used to quantify M2 and M3 subtypes in isolated detrusor muscle and urothelium. In addition, pig bladder muscle and urothelial receptors were quantified for comparison. Results In the human urothelium total, M2 and M3 muscarinic receptor density is significantly negatively correlated with the affinity of darifenacin for inhibition of contraction of the detrusor muscle. In the detrusor muscle there is no correlation between receptor density and darifenacin affinity for inhibition of contraction. Muscarinic receptor density is greater in the muscle than in the urothelium in human bladders whereas in the pig bladder the density is greater in the urothelium than in the muscle. Conclusions The greater density of urothelial muscarinic receptors in human bladders with lower darifenacin affinity, indicative of a greater contribution of M2 receptors to the contractile response, points towards a possible role of the urothelium in controlling M2 mediated contractile phenotype. In comparison between human and pig bladders, the distribution of muscarinic receptor subtypes in the muscle and urothelium are quite different. Neurourol. Urodynam. © 2006 Wiley-Liss, Inc. [source] Information transmission in electronic versus open-outcry trading systems: An analysis of U.S. equity index futures marketsTHE JOURNAL OF FUTURES MARKETS, Issue 7 2005Aysegul Ates In this article the intraday price discovery process between regular index futures (floor trading) and E-mini index futures (electronic trading) in the S&P 500 and Nasdaq 100 index futures markets is examined, using intraday data from the introduction of the E-mini index futures to 2001. Using both information shares (Hasbrouck, J., 1995) and common long-memory factor weights (Gonzalo, J., & Granger, C. W. J., 1995) techniques, we find that both E-mini index futures and regular index futures contribute to the price discovery process. However, since September 1998, the contribution made by E-mini index futures has been greater than that provided by regular index futures. Based on regression analysis, we have also found direct empirical evidence to support the hypothesis that the joint effects of operational efficiency and relative liquidity determine the greater contribution made towards price discovery by electronic trading relative to open-outcry trading over time. © 2005 Wiley Periodicals, Inc. Jrl Fut Mark 25: 679,715, 2005 [source] 18F-fluorodeoxyglucose,positron emission tomography scanning is more useful in followup than in the initial assessment of patients with Erdheim-Chester diseaseARTHRITIS & RHEUMATISM, Issue 10 2009Laurent Arnaud Objective Erdheim-Chester disease (ECD) is a rare form of non,Langerhans' cell histiocytosis. The aim of this study was to assess the value of whole-body scanning with 18F-fluorodeoxyglucose,positron emission tomography (FDG-PET) in a large cohort of ECD patients from a single center. Methods We retrospectively reviewed all PET scans performed on 31 patients with ECD who were referred to our department between 2005 and 2008. PET images were reviewed by 2 independent nuclear medicine specialist physicians and were compared with other imaging modalities performed within 15 days of each PET scan. Results Thirty-one patients (10 women and 21 men; median age 59.5 years) underwent a total of 65 PET scans. Twenty-three patients (74%) were untreated at the time of the initial PET scan, whereas 30 of the 34 followup PET scans (88%) were performed in patients who were undergoing immunomodulatory therapy. Comparison of the initial and followup PET scans with other imaging modalities revealed that the sensitivity of PET scanning varied greatly among the different organs studied (range 4.3,100%), while the specificity remained high (range 69.2,100%). Followup PET scans were particularly helpful in assessing central nervous system (CNS) involvement, since the PET scan was able to detect an early therapeutic response of CNS lesions, even before magnetic resonance imaging showed a decrease in their size. PET scanning was also very helpful in evaluating the cardiovascular system, which is a major prognostic factor in ECD, by assessing the heart and the entire vascular tree during a single session. Conclusion The results of our large, single-center, retrospective study suggest that the findings of a FDG-PET scan may be interesting in the initial assessment of patients with ECD, but its greater contribution is in followup of these patients. [source] Green light for greener supplyBUSINESS ETHICS: A EUROPEAN REVIEW, Issue 4 2002Lutz Preuss The supply chain management function is currently undergoing a dramatic change: it is adopting an increasingly strategic role. However, this growing financial importance is matched in only a handful of exemplary companies by a greater contribution to environmental protection initiatives in the supply chain. This paper explores some of the obstacles to greater supply chain management involvement in environmental protection and offers suggestions for greener supply. At a personal level, the gap between public opinion on the environment and managerial values needs to be closed, and the support offered by management education and by professional bodies needs to be improved. Within the organisation, the reward structure for supply chain managers needs to move away from narrow economic criteria. Greener supply would also benefit from a larger supply chain management role in corporate strategy making; the function could even be offered a seat on the Board of Management. Changes to the mode of supply chain management, including improvements to the information flow on environmental issues, the decision,making tools used in the face of complex environmental challenges and novel approaches to supply chain management need to receive urgent attention. [source] Agricultural and Rural Development in China: Achievements and Challenges Entwicklung der Landwirtschaft und des ländlichen Raums in China: Erfolge und Herausforderungen Le développement agricole et rural en Chine : résultats et défisEUROCHOICES, Issue 2 2009Chen Xiaohua Summary Agricultural and Rural Development in China: Achievements and Challenges China has made great advances in its agricultural and rural development since the reforms and opening-up that began in 1978. It has not only fed its population of 1.3 billion, but has also contributed to international agricultural development and food security. Agricultural production registered great development, providing sufficient food and clothes for 21 per cent of the world's population with 9 per cent of the arable land. In the process farmers' living standards improved remarkably and rural public utilities and services were greatly enhanced. China is now in a key transition period of accelerating the transformation and modernisation of traditional agriculture and rural society. It is facing significant challenges. Agriculture is still one of the weakest industries in China and it is proving difficult to sustain increases in grain output and farmers' incomes. The problems of uneven development in rural areas have become increasingly prominent and the gap between urban and rural development is tending to widen. The Chinese government will respond strategically to these challenges and will firmly pursue the construction of a new efficient and sustainable socialist countryside, along the path of modernisation with Chinese characteristics. It will also make greater contributions to world agriculture and rural development. Les progrès de la Chine en termes de développement agricole et rural depuis le début des réformes et l'ouverture en 1978 ont été considérables. Non seulement le pays a nourrit une population de 1.3 millions d'habitants mais il a contribué au développement et à la sécurité alimentaire au niveau international. La production agricole a fortement augmenté et a fournit suffisamment de nourriture et de vêtements à 21 pour cent de la population du monde avec 9 pour cent des terres cultivables. Ce processus s'est accompagné d'une hausse considérable du niveau de vie des agriculteurs et d'une grande amélioration des services publics dans les zones rurales. La Chine est maintenant à un moment clé de sa période de transition, caractérisé par une accélération de la transformation et de la modernisation de l'agriculture et de la société rurale traditionnelles. Des défis importants se présentent à elle. L'agriculture reste une des industries chinoises les plus fragiles et il se révèle difficile de continuer à augmenter la production céréalière et les revenus des agriculteurs. Les problèmes d'inégalité de développement dans les zones rurales deviennent de plus en plus visibles et l'écart de développement entre les zones urbaines et les zones rurale tend à s'accroître. Les pouvoirs publics chinois vont apporter une réponse stratégique à ces défis et vont poursuivre fermement la construction d'une nouvelle campagne socialiste efficace et durable, en suivant une voie de modernisation typiquement chinoise. Ils vont aussi accroître les contributions de la Chine au développement agricole et rural mondial. Seit Beginn der Reformen und der Öffnungspolitik 1978 hat sich Chinas Landwirtschaft und ländlicher Raum enorm weiterentwickelt. China hat seitdem nicht nur seine 1.3 Milliarden Einwohner ernährt, sondern auch zur internationalen Agrarentwicklung und Ernährungssicherung beigetragen. Die Agrarproduktion wurde erheblich ausgeweitet und deckt nun 21 Prozent des weltweiten Bedarfs an Lebensmitteln und Kleidung bei gerade einmal 9 Prozent der Weltackerfläche. Dabei haben sich die Lebensbedingungen für die Landwirte sowie das Angebot an öffentlichen Einrichtungen und Dienstleistungen im ländlichen Raum deutlich verbessert. China durchläuft gerade eine wichtige Übergangsphase, in der sich der Wandel und die Modernisierung der traditionellen Landwirtschaft und der Landbevölkerung noch schneller vollziehen, und steht großen Herausforderungen gegenüber. Die Landwirtschaft ist nach wie vor einer der schwächsten Sektoren in China, und es erweist sich als schwierig, die Steigerungsraten bei der Getreideerzeugung und den Einkommen in der Landwirtschaft aufrecht zu erhalten. Die Probleme der ungleichmäßigen Entwicklung in ländlichen Gebieten werden immer offensichtlicher, und die Kluft zwischen städtischer und ländlicher Entwicklung droht sich auszuweiten. Die chinesische Regierung wird diesen Herausforderungen strategisch begegnen und , ganz im Sinne einer Modernisierung mit chinesischen Merkmalen , daran festhalten, einen neuen sozialistischen ländlichen Raum effizient und nachhaltig zu gestalten. Sie wird ebenfalls einen noch größeren Beitrag zur Weltlandwirtschaft und zur Entwicklung des ländlichen Raums leisten. [source] Temperature responses are a window to the physiology of dark respiration: differences between CO2 release and O2 reduction shed light on energy conservationPLANT CELL & ENVIRONMENT, Issue 7 2008JÖRG KRUSE ABSTRACT We showed that temperature responses of dark respiration for foliage of Pinus radiata could be approximated by Arrhenius kinetics, whereby E0 determines shape of the exponential response and denotes overall activation energy of respiratory metabolism. Reproducible and predictable deviation from strict Arrhenius kinetics depended on foliage age, and differed between RCO2 and RO2. Inhibition of oxygen reduction (RO2) by cyanide (inhibiting COX) or SHAM (inhibiting AOX) resulted in reproducible changes of the temperature sensitivity for RO2, but did not affect RCO2. Enthalpic growth , preservation of electrons in anabolic products , could be approximated with knowledge of four variables: activation energies (E0) for both RCO2 and RO2, and basal rates of respiration at a low reference temperature (RREF). Rates of enthalpic growth by P. radiata needles were large in spring due to differences between RREF of oxidative decarboxylation and that of oxygen reduction, while overall activation energies for the two processes were similar. Later during needle development, enthalpic growth was dependent on differences between E0 for RCO2 as compared with RO2, and increased E0(RO2) indicated greater contributions of cytochrome oxidase to accompany the switch from carbohydrate sink to source. Temperature-dependent increments in stored energy can be calculated as the difference between RCO2,HCO2 and RO2,HO2. [source] | |||||||||||||||||||