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Great Expectations (great + expectation)
Selected AbstractsThe superego, narcissism and Great ExpectationsTHE INTERNATIONAL JOURNAL OF PSYCHOANALYSIS, Issue 3 2007Graham Ingham The author notes that the concepts of the superego and narcissism were linked at conception and that superego pathology may be seen as a determining factor in the formation of a narcissistic disorder; thus an examination of the superego can function as a ,biopsy', indicating the condition of the personality as a whole. Charles Dickens's novel Great Expectations is presented as a penetrating exploration of these themes and it is argued that in Pip, the central character, Dickens provides a perceptive study of the history of a narcissistic condition. Other key figures in the book are understood as superego representations and, as such, integral to the vicissitudes of Pip's development. In particular, the lawyer Jaggers is considered as an illustration of Bion's notion of the ,ego-destructive superego'. In the course of the paper, the author suggests that Great Expectations affirms the psychoanalytic understanding that emotional growth and some recovery from narcissistic difficulties necessarily take place alongside modification of the superego, allowing for responsible knowledge of the state of the object and the possibility of realistic reparation. [source] The Ancillary-Care Responsibilities of Researchers: Reasonable But Not Great ExpectationsTHE JOURNAL OF LAW, MEDICINE & ETHICS, Issue 4 2007Roger Brownsword This paper argues that, in a community of rights, the prima facie responsibilities of researchers to attend to the ancillary-care needs of their participants would be determined by a four-stage test (relating to placement, capacity, reasonable imposition, and fair demand). This test, it is suggested, sets a standard (and an example) for common law courts that are invited to recognize the ancillary-care responsibilities of researchers, whether as a matter of contract or tort law. [source] Great Expectations: Strategy as Creative FictionBUSINESS STRATEGY REVIEW, Issue 3 2005Peter Brews First page of article [source] Renin-angiotensin system revisitedJOURNAL OF INTERNAL MEDICINE, Issue 3 2008F. Fyhrquist Abstract. New components and functions of the renin-angiotensin system (RAS) are still being unravelled. The classical RAS as it looked in the middle 1970s consisted of circulating renin, acting on angiotensinogen to produce angiotensin I, which in turn was converted into angiotensin II (Ang II) by angiotensin-converting enzyme (ACE). Ang II, still considered the main effector of RAS was believed to act only as a circulating hormone via angiotensin receptors, AT1 and AT2. Since then, an expanded view of RAS has gradually emerged. Local tissue RAS systems have been identified in most organs. Recently, evidence for an intracellular RAS has been reported. The new expanded view of RAS therefore covers both endocrine, paracrine and intracrine functions. Other peptides of RAS have been shown to have biological actions; angiotensin 2,8 heptapeptide (Ang III) has actions similar to those of Ang II. Further, the angiotensin 3,8 hexapeptide (Ang IV) exerts its actions via insulin-regulated amino peptidase receptors. Finally, angiotensin 1,7 (Ang 1,7) acts via mas receptors. The discovery of another ACE2 was an important complement to this picture. The recent discovery of renin receptors has made our view of RAS unexpectedly complex and multilayered. The importance of RAS in cardiovascular disease has been demonstrated by the clinical benefits of ACE inhibitors and AT1 receptor blockers. Great expectations are now generated by the introduction of renin inhibitors. Indeed, RAS regulates much more and diverse physiological functions than previously believed. [source] Sharing the Vision: Healthy, Achieving Students What Can Schools Do?JOURNAL OF SCHOOL HEALTH, Issue 5 2000James M. Caccamo It was a beautiful spring day. The sky was a deep azure with not a cloud in sight. The cool breeze was gently flowing over two friends who were wading into the stream for a relaxing morning of trout fishing. Calmly and with rhythmic grace, the two cast their flies with great expectation. Suddenly, one of the fishermen spotted a baby floating down the stream. He threw his rod on the bank and ran to pull the baby out of the stream. Placing the baby on the bank, he noticed another floating down the stream. In a panic, he rushed back into the water to retrieve that baby. When he had placed the second baby safely on the bank, he noticed a third and a fourth floating in the stream. His friend, who was still fishing, quietly walked out of the water, gently placed his rod on the bank and began walking upstream. The fisherman who was frantically trying to save the babies yelled, "Where are you going? I need your help to save these babies." His buddy turned and said, "I am going upstream to stop the person who is putting the babies in the water." [source] The Water Framework Directive and agricultural nitrate pollution: will great expectations in Brussels be dashed in Lower Saxony?ENVIRONMENTAL POLICY AND GOVERNANCE, Issue 4 2007Britta Kastens Abstract This paper discusses the opportunities and constraints regarding the effective implementation of the European Water Framework Directive (WFD) in the area of diffuse nitrate pollution. Owing to the subsidiarity principle and a new procedural mode of governance, the WFD only sets distinct environmental targets, leaving most decisions on how to operationalize and institutionalize the reduction of diffuse nitrate pollution to the member states. This is a particular challenge for Germany, where lower scale regions have become the main implementers of European water policy. Successful implementation of the WFD, i.e. the actual improvement of water quality, depends on a series of key contextual and contingent factors, operating at a regional scale. In a Northwest German region with intensive agriculture and severe nitrate pollution, we analyse the historical and economic context and actor network of the region as well as the influence of environmental groups on public participation, the potential of biogas technology and new financial options. Besides the specific influence of these factors on the implementation process, we explore the uncertainties and difficulties surrounding European legislation and its operationalization in Germany and on a regional scale. Copyright © 2007 John Wiley & Sons, Ltd and ERP Environment. [source] Adult stem cell plasticity: will engineered tissues be rejected?INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY, Issue 3 2004Te-Chao Fang Summary The dogma that adult tissue-specific stem cells remain committed to supporting only their own tissue has been challenged; a new hypothesis, that adult stem cells demonstrate plasticity in their repertoires, is being tested. This is important because it seems possible that haematopoietic stem cells, for example, could be exploited to generate and perhaps deliver cell-based therapies deep within existing nonhaematopoietic organs. Much of the evidence for plasticity derives from histological studies of tissues from patients or animals that have received grafts of cells or whole organs, from a donor bearing (or lacking) a definitive marker. Detection in the recipient of appropriately differentiated cells bearing the donor marker is indicative of a switch in phenotype of a stem cell or a member of a transit amplifying population or of a differentiated cell. In this review, we discuss evidence for these changes occurring but do not consider the molecular basis of cell commitment. In general, the extent of engraftment is low but may be increased if tissues are damaged. In model systems of liver regeneration, the repeated application of a selection pressure increases levels of engraftment considerably; how this occurs is unclear. Cell fusion plays a part in regeneration and remodelling of the liver, skeletal muscle and even regions of the brain. Genetic disease may be amenable to some forms of cell therapy, yet immune rejection will present challenges. Graft- vs. -host disease will continue to present problems, although this may be avoided if the cells were derived from the recipient or they were tolerized. Despite great expectations for cellular therapies, there are indications that attempts to replace missing proteins could be confounded simply by the development of specific immunity that rejects the new phenotype. [source] Tourism in Dubai: overcoming barriers to destination developmentINTERNATIONAL JOURNAL OF TOURISM RESEARCH, Issue 2 2006Joan C. Henderson Abstract The Middle East as a whole attracts comparatively few visitors, and political events in the current century have generated new uncertainties and tensions which seem likely to further discourage tourists and investors. Additional barriers relate to poor accessibility, a perceived lack of conventional attractions and limited promotion. Despite these apparently unfavourable circumstances, international tourism has been adopted by the Dubai authorities as a core element in a programme of economic diversification. They have invested heavily in expensive facilities, as well as undertaken extensive marketing, and the outcome has been strong growth in tourism. There are great expectations of the future, reflected in the setting of very high arrival targets. However, there are also several constraints that might inhibit progress, with a need to review strategies. The experience of Dubai thus serves to illustrate factors that are critical to destination development, major impediments and approaches to overcoming these. Copyright © 2006 John Wiley &Sons, Ltd. [source] Asthma management in rural New South Wales: Perceptions of health care professionals and people with asthmaAUSTRALIAN JOURNAL OF RURAL HEALTH, Issue 4 2009Biljana Cvetkovski Abstract Objective:,To investigate the perceptions and attitudes towards asthma management of general practitioners, pharmacists and people with asthma in a rural area. Design:,Qualitative semistructured interviews. Setting:,Small rural centre in New South Wales. Participants:,General practitioners, pharmacists and people with asthma in a rural area. Results:,General practitioners perceived that the patient provided a barrier to the implementation of optimal asthma services. They were aware that other health care professionals had a role in asthma management but were not aware of the details, particularly in relation to that of the pharmacist and would like to improve communication methods. Pharmacists also perceived the patient to be a barrier to the delivery of optimal asthma management services and would like to improve communication with the general practitioner. The impact of the rural environment for the health care professionals included workforce shortages, availability of support services and access to continuing education. People with asthma were satisfied with their asthma management and the service provided by the health care professionals and described the involvement of family members and ambulance officers in their overall asthma management. The rural environment was an issue with regards to distance to the hospital during an emergency. Conclusions:,General practitioners and pharmacists confirmed their existing roles in asthma management while expressing a desire to improve communication between the two professions to help overcome barriers and optimise the asthma service delivered to the patient. The patient described minimal barriers to optimising asthma management, which might suggest that they might not have great expectations of asthma care. [source] | |||||||||||||