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Good Functional (good + functional)

Distribution by Scientific Domains

Medical Sciences	83%

Terms modified by Good Functional

good functional outcome

good functional property

good functional result

Selected Abstracts

Peripheral nerve regeneration in cell adhesive peptide incorporated collagen tubes in rat sciatic nerve , early and better functional regain

JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM, Issue 4 2005
Mohamed Rafiuddin Ahmed
[source]

Replantation of amputated finger composite tissues with microvascular anastomosis

MICROSURGERY, Issue 5 2008
Yimin Chai M.D.
Replantation of the partial amputated finger or the composite tissue in finger would achieve better functional and esthetical results than any reconstructive procedure. In this article, we report the results of microsurgical partial finger or composite tissue replantation at different anatomic sites of 24 fingers in 21 patients. Microvascular anastomosis was performed in all cases of replantation. For the digital palmar and lateral composite tissue defects, the proper palmar digital artery and volar or dorsal subcutaneous veins were repaired by end-to-end anastomoses. For the digital dorsal defects, the blood supply was reestablished by arterialization of a dorsal central vein in the replanted part with one of the proper palmar digital arteries. The average follow-up period was 12.3 months. Twenty-two of 24 fingers survived completely with good functional and esthetic results. Two replantations failed because of vascular complications. In conclusion, if the vascular vessels in amputations of partial finger and composite tissue of finger are suitable for anastomosis, a successful replantation of these parts with excellent functional and esthetical recovery can be achieved. © 2008 Wiley-Liss, Inc. Microsurgery, 2008. [source]

Treatment of Widespread Segmental Nevus Spilus by Q-Switched Alexandrite Laser (755 nm, 100 nsec)

DERMATOLOGIC SURGERY, Issue 9 2001
G.A. Moreno-Arias MD
Background. Widespread unilateral nevus spilus causes important cosmetic and psychological disturbances, and only a few therapeutic options can guarantee good functional and cosmetic results. Objective. To evaluate the clinical response of a patient with widespread segmental nevus spilus to Q-switched (QS) alexandrite laser. Methods. The treatment was QS alexandrite laser (755 nm, 100 nsec) with a mean fluence of 7.28 ± 0.37 J/cm2 using a single-impact technique at 10 ± 8.47-week intervals. Results. Fifty percent clearance of the facial portion of the lesion was observed after 16 treatment sessions with QS alexandrite laser. Conclusion. QS alexandrite laser is suitable for removal of widespread segmental nevus spilus. [source]

Rheological and Functional Properties of Catfish Skin Protein Hydrolysates

JOURNAL OF FOOD SCIENCE, Issue 1 2010
Huaixia Yin
ABSTRACT:, Catfish skin is an abundant and underutilized resource that can be used as a unique protein source to make fish skin protein hydrolysates. The objectives of this study were to isolate soluble and insoluble proteins from hydrolyzed catfish skin, study the rheological and functional properties of the protein hydrolysates, and evaluate the properties of emulsions made from the protein powders. Freeze-dried catfish skin soluble (CSSH) and insoluble hydrolysate (CSISH) powders were analyzed for proximate analysis, emulsion stability, fat absorption, amino acids, color, and rheological properties. CSSH had significantly (P,< 0.05) higher protein, ash, and moisture content but lower fat content than that of CSISH. The yield of CSSH (21.5%± 2.2%) was higher than that of CSISH (3%± 0.3%). CSISH had higher emulsion stability than CSSH. CSSH was light yellow in color and CSISH was darker. The mean flow index values for emulsion containing CSSH (ECSSH) and CSISH (ECSISH) were both less than 1, indicating that they were both pseudoplastic fluid. The G, and G, values for the ECSISH were higher than that of ECSSH, indicating that the viscoelastic characteristic of the emulsion containing CSISH was greater than that of the emulsion containing CSSH. The study demonstrated the CSSH and CSISH had good functional and rheological properties. They have potential uses as functional food ingredients. [source]

Scrotal reconstruction with a free greater omental flap: A case report

MICROSURGERY, Issue 5 2010
Darren Ng M.B.B.S., M.R.C.S.
We report a case of Fournier's gangrene, where we used the greater omentum as a free flap for scrotal reconstruction and outline the advantages over previously described methods. The greater omentum was harvested using a standard open technique. The deep inferior epigastric vessels were passed through the inguinal canal into the scrotal area as recipient vessels. The detached greater omental flap was prefabricated into a three-dimensional sac prior to inset and microvascular anastomoses. The flap was then covered by skin graft. The reconstruction had shown good early results with complete survival of the flap, as well as good functional and esthetic outcome at six months. The greater omentum can therefore be used as a free flap for scrotal reconstruction. It allows easy prefabrication and flap inset. The deep inferior epigastric vessels are also suitable recipient vessels. © 2010 Wiley-Liss, Inc. Microsurgery 30:410,413, 2010. [source]

One-stage reconstruction of the complex midfoot defect with a multiple osteotomized free fibular osteocutaneous flap: Case report and literature review

MICROSURGERY, Issue 1 2010
Efstathios G. Lykoudis M.D., Ph.D.
Complex midfoot defects represent a reconstructive challenge since midfoot plays a key role in standing and gait. We report the case of a 27-year-old patient with a complex midfoot defect due to a high-energy gun shot injury. The defect included the tarsometatarsal complex, all three arches of the foot, and the overlying dorsal skin of the foot. Reconstruction was achieved in a single stage with a free fibular osteocutaneous flap. The fibula was osteotomized into three segments, which were used to reconstruct the bone defects, while the skin paddle of the flap was used for stable soft tissue coverage of the reconstructed bony skeleton. Early and late postoperative periods were uneventful. Bone incorporation was radiographically evident at 12 weeks, and full weight bearing was possible at 6 months postop. Final follow up, at 2 years postop, showed a very good functional and esthetic outcome. © 2009 Wiley-Liss, Inc. Microsurgery, 2010. [source]

Replantation of amputated finger composite tissues with microvascular anastomosis

Microsurgical reconstruction of brachial artery injuries in displaced supracondylar fracture humerus in children

MICROSURGERY, Issue 7 2006
Hassan H. Noaman M.D.
Between March 2000 and March 2005, 840 children with grade III supracondylar humeral fractures presented for treatment, consecutively at our hospital. One hundred twenty had absent or diminished (detected by Doppler but not palpable) radial pulse on initial examination. Eighty-nine of these 120 children recovered pulse (palpable) after closed reduction and percutaneous pinning of the fracture. The remaining 31 children had persistent absent radial pulse. Twenty-two of the 31 children had median nerve signs. Each of these 31 children was explored. The intraoperative findings were intact median nerve in all cases (neuropraxia), traumatic aneurysm with thrombus formation in 17 cases, complete injury of the brachial artery in 8 cases (loss of continuity), thrombosis in 3 cases, partial tear in 2 cases, and brachial artery entrapment in the fracture site in 1 case. Microsurgical reconstruction of the 31 brachial arteries was done as the following: reversed vein graft for 8 cases, excision and repair in 17 cases, partial repair in 2 cases, thrombectomy in 3 cases, and release of the brachial artery from the fracture site in 1 case. The average follow up was 26 months range (6,60) months. All children had excellent to good functional and cosmetic outcome except one who had Volkman's ischemic contracture, treated later by free functioning gracilis muscle transfer. © 2006 Wiley-Liss, Inc. Microsurgery, 2006. [source]

The good initial response to therapy with a combination of traditional disease-modifying antirheumatic drugs is sustained over time: The eleven-year results of the Finnish rheumatoid arthritis combination therapy trial

ARTHRITIS & RHEUMATISM, Issue 5 2009
Vappu Rantalaiho
Objective To evaluate the evolution of functional and clinical outcomes over 11 years in patients with early rheumatoid arthritis (RA) initially treated with a combination of 3 disease-modifying antirheumatic drugs (DMARDs) or with a single DMARD. Methods A cohort of 199 patients with early active RA were initially randomized to receive treatment with a combination of methotrexate, sulfasalazine, and hydroxychloroquine with prednisolone or treatment with a single DMARD (initially, sulfasalazine) with or without prednisolone. After 2 years, the drug treatment strategy became unrestricted, but still targeted remission. At 11 years, function was assessed with the Health Assessment Questionnaire (HAQ), and clinical outcomes were assessed with the modified Minimal Disease Activity (MDA) measure and the American College of Rheumatology (ACR) criteria for remission. Results At 11 years, 138 patients were assessed (68 in the combination-DMARD group and 70 in the single-DMARD group). The mean ± SD HAQ scores were 0.34 ± 0.54 in the combination-DMARD group and 0.38 ± 0.58 in the single-DMARD group (P = 0.88). Modified MDA was achieved by 63% (95% confidence interval [95% CI] 51, 77) and by 43% (95% CI 32, 55) (P = 0.016) of the combination-DMARD group and the single-DMARD group, respectively, and ACR remission by 37% (95% CI 26, 49) and by 19% (95% CI 11, 29) (P = 0.017), respectively. Conclusion Initial therapy with a combination of DMARDs in early RA results in higher rates of patients achieving modified MDA and strict ACR remission even over the long term than initial single-DMARD therapy. Targeting remission with tight clinical controls results in good functional and clinical outcomes in most RA patients. [source]

The urethral Kock pouch: long-term functional and oncological results in men

BJU INTERNATIONAL, Issue 4 2003
A.A. Shaaban
The Department of Urology in Mansoura has a well-known experience in, among many things, urinary tract reconstruction in patients with bladder cancer. They review their results in 338 male patients who had a radical cystectomy and Kock pouch. They found good functional and oncological outcomes in properly selected patients. However, they also drew attention to several valve-related complications. OBJECTIVE To evaluate our experience with men who underwent radical cystectomy and urethral Kock pouch construction between January 1986 and January 1996. PATIENTS AND METHODS Complications were classified as early (within the first 3 months after surgery) or late. Continence was assessed by interviewing the patient; they were considered continent if they were completely dry with no need of protection by pads, condom catheter or medication. The patients were followed oncologically and Kaplan-Meier survival curves constructed. Urodynamic studies were used to define the possible causes of enuresis. RESULTS Three patients died after surgery from pulmonary embolism. There were 67 early complications in 63 patients. The mean (sd) follow-up was 87.8 (49.1) months. There were 111 treatment failures from cancer; of these, four men only had an isolated local recurrence in the urethra. Late complications included 72 pouch stones in 55 patients, and 36 deteriorated renal units caused by reflux (17), uretero-ileal stricture (11), nipple valve eversion (four) or stenosis (four). Interestingly, 65 renal units that were dilated before surgery improved significantly afterward. Ileo-urethral strictures occurred in seven men and anterior urethral strictures in six. Nine patients were totally incontinent and two had chronic urinary retention. Daytime continence was complete in 94% of men, with nocturnal enuresis in 55; the latter had significantly more residual urine, and a higher amplitude and duration of phasic contractions. CONCLUSIONS Orthotopic bladder substitution after cystectomy for cancer is feasible, with good functional and oncological outcomes in properly selected patients. Nevertheless, the use of a hemi-Kock pouch is associated with many valve-related complications. [source]

3 Intravitreal ranibizumab injections series for the treatment of neovascular age-related macular degeneration (AMD), 18 months follow-up

ACTA OPHTHALMOLOGICA, Issue 2009
C GONZALEZ
Purpose To evaluate the functional, anatomical, vascular flow effects of intravitreal Ranibizumab injections(IVT) for retrofoveolar neovascular AMD, done with a series of 3 IVT protocol, and the recurrences frequency at 1 ½ year evolution. Methods 227 eyes of 179 patients, 58 men, 121 women, with retrofoveolar neovascularisation complicating AMD. Patients received intravitreous Ranibizumab, 3 times, every 4 weeks in an inductive treatment. The next injections depended on the follow-up results, and were done by series of 3. First and 2 months' interval follow-up exam included ETDRS visual acuity (VA), complete ophthalmic examination, fluorescein and infracyanine (ICG) angiography, and optical coherence tomography (OCT).VA and OCT were done before each IVT. We want to evaluate the incidence of this protocol on the frequency of recurrences so on the number of IVT needed. Results VA improved in 48% cases, more than 10 letters in 25% cases. Angiographic leakage reduced about 70% in 53% cases. At ICG ,vascular flow, vessel's diameter were 2/3 time less in 62% cases. Diffuse edema was 30% reduced in 85% , pigment epithelial detachment was flattened and less dense in all cases, by OCT. Most of patients had good functional, anatomical, vascular flow, results, with less IVT needed. Inductive treatment was sufficient in 113 cases,more series were necessary in 114 cases.Mean stability period was 3 months. Conclusion The results, with generally improved visual function, less and/or stable neovascular activity in FA-ICG-OCT, less recurrences, suggest series of 3 Ranibizumab IVT seem effective, less restrictive,more retinal protective, lastly cheaper. This protocol seems attractive, its indication must be optimized. [source]

Recent Advances in the Recovery and Improvement of Functional Proteins from Fish Processing By-Products: Use of Protein Glycation as an Alternative Method

COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY, Issue 4 2009
Esther Sanmartín
ABSTRACT:, The recovery of proteins from fish by-products for their utilization as food ingredients is becoming of increasing interest in the food industry as they may possess good functional and nutritional properties. This article reviews the main processing methods, such as enzymatic hydrolysis, pH shifting, membrane filtration, and some emerging technologies, used for the recovery of proteins from fish processing by-products. The impact of these methods on the yield and, especially, on the functionality of the recovered proteins is discussed in detail. Considering that there is a huge amount of fish by-products destined for nonfood use, one of the current challenges of the food industry is the development of technologies that allow the recovery of ingredients from the fish processing by-products with potential to provide new and natural sources of high-value functional ingredients for human consumption. In this sense, this review explores the potential use of the glycation reaction to increase the yield of proteins extracted from fish by-products, as well as the effect of this reaction on their functional and biological properties. [source]