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Ganglia Lesions (ganglia + lesion)

Distribution by Scientific Domains
Medical Sciences100%

Kinds of Ganglia Lesions

  • basal ganglia lesion
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    Selected Abstracts

    The pedunculopontine nucleus in developmental disorders of the basal ganglia

    NEUROPATHOLOGY, Issue 3 2008
    Yuki Anzai
    The pedunculopontine nucleus (PPN), which is located in the upper brainstem, contains cholinergic and non-cholinergic neurons, and has afferent and efferent connections to the basal ganglia and spinal cord. The PPN is known to be affected in adult-onset basal ganglia diseases, and we speculated that the PPN might be similarly insulted in developmental basal ganglia disorders. We immunohistochemically examined the expression patterns of acetylcholine esterase and tyrosine hydroxylase, markers of acetylcholinergic and catecholaminergic neurons, respectively, in the PPN pars dissipata (PPNd) of controls and patients with bilirubin encephalopathy (BE) and perinatal hypoxic ischemic encephalopathy with localized basal ganglia lesion (HIEbg). Controls showed an age-dependent change in the percentages of acetylcholinergic and catecholaminergic neurons. Three out of six BE cases and three out of six HIEbg cases showed a reduction in the percentage of acetylcholinergic neurons in the PPNd. Additionally, three BE cases demonstrated an increase in the percentage of catecholaminergic neurons. It is likely that the relative proportions of acetylcholinergic and catecholaminergic neurons in the PPN can be altered in developmental basal ganglia disorders. [source]

    Magnetic Resonance Imaging and Diffusion-Weighted Imaging Changes After Hypoglycemic Coma

    JOURNAL OF NEUROIMAGING, Issue 2 2005
    S. L. Jung
    ABSTRACT The authors report a case of severe hypoglycemic encephalopathy in an elderly patient. The magnetic resonance images showed bilateral cortical signal changes and basal ganglia lesions, which spared the thalami. The lesions were bright on fluid-attenuated inversion recovery and diffusion-weighted images and dark on the apparent diffusion coefficient map, being more conspicuous on the diffusion-weighted images than on the fluid-attenuated inversion recovery images. A literature review of the imaging features and pathophysiological mechanism in comparison with those of hypoxic ischemic injury is discussed. [source]

    Hypoglycemia-induced choreoathetosis associated with hyperintense basal ganglia lesions in T1-weighted brain MRI,

    MOVEMENT DISORDERS, Issue 7 2010
    Martin Wolz PhD
    No abstract is available for this article. [source]

    Dystonia associated with hyperintense basal ganglia lesions on T1-weighted brain MRI

    MOVEMENT DISORDERS, Issue 11 2008
    Martin Wolz MD
    [source]

    A new case of pyruvate dehydrogenase deficiency due to a novel mutation in the pdx1 gene

    ANNALS OF NEUROLOGY, Issue 2 2003
    Runu Dey PhD
    We report a case of neonatal congenital lactic acidosis associated with pyruvate dehydrogenase E3-binding protein deficiency in a newborn girl. She had a severe encephalopathy, and magnetic resonance imaging of the brain showed large subependymal cysts and no basal ganglia lesions. She died 35 days after birth. We detected a novel homozygous deletion (620delC) in the PDX1 gene, which encodes for the E3BP subunit of the pyruvate dehydrogenase complex. [source]