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Functional Measurements (functional + measurement)
Selected AbstractsProfessional Basketball's Unsportsmanlike Fouls in the Eyes of the BeholdersAPPLIED PSYCHOLOGY, Issue 3 2010Michael Bar-Eli A series of three experiments, based on the method of Functional Measurement, has explored the importance assigned by professional basketball players to relevant dispositions of defense and offense players, as determinants of unsportsmanlike fouls. The 106 participants were leading male players in the premier basketball league in Israel. Experiment 1 was based on a 16 (24)-cell model. In an individual meeting, each participant estimated the likelihood that a defense player would commit an unsportsmanlike foul on an offense player. In each of the 16 to-be-judged incidents, specific information on a specific combination of aggressiveness and susceptibility to victimisation of two imaginary protagonists in an offense,defense on-the-court incident was given to the participant. Experiment 2 was a replication of Experiment 1. There, however, names of 16 well-known players were mentioned, the aggressiveness and susceptibility to victimisation of each fitting the model requirements. In Experiment 3, a partial replication of Experiment 2, likelihood estimations were made from two perspectives,potential perpetrator and potential victim. Overall, meaningful importance was assigned especially to the dispositions of the perpetrator, not the victim. The findings are conceived as reflections of players' cognitive schemata of on-the-court violence. Basée sur la méthode de la mesure fonctionnelle, une série de 3 expérimentations a exploré l'importance que des joueurs de basket professionnels attribuent aux dispositions de joueurs attaquant ou défenseur à commettre des fautes anti sportives. Les 106 sujets sont des joueurs de sexe masculin de la ligue 1 de basket israélienne. L'expérience 1 est basée sur un modèle à 16 (24) cases. Lors de passation individuelle, chaque participant estime la probabilité qu'un joueur arrière commette une faute anti sportive sur un joueur avant. Pour chacun des 16 incidents à juger, une information spécifique a été donnée aux participants. Il s'agissait d'une combinaison particulière de l'agressivité et de la propension à la victimisation des deux protagonistes imaginaires dans une situation d'incident soit offensif soit défensif sur le terrain. L'expérimentation 2 est une réplique de la première. Cependant, les noms de 16 joueurs connus sont mentionnés, l'agressivité et la propension à la victimisation étaient appropriées aux exigences du modèle. Dans l'expérience 3, réplique partielle de la deuxième, la probabilité des estimations a été faite selon deux perspectives: auteur potentiel et victime potentielle. Globalement, une importance significative a été assignée aux dispositions de l'auteur et non de la victime. Les résultats sont conçus comme reflétant le schéma cognitif des joueurs lors de violence sur le terrain. [source] Visualization of therapeutic arteriogenesis by MR angiography: Functional measurements are superior to surrogate parametersJOURNAL OF MAGNETIC RESONANCE IMAGING, Issue 1 2007Anja Bondke M.D. [source] Assessment and prevention of gastrointestinal toxicity of non-steroidal anti-inflammatory drugsJOURNAL OF PHARMACY AND PHARMACOLOGY: AN INTERNATI ONAL JOURNAL OF PHARMACEUTICAL SCIENCE, Issue 10 2006Majella E. Lane Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used for analgesic, anti-inflammatory and, in the case of aspirin, for anti-thrombotic actions. The serious gastrointestinal side-effects associated with these drugs are of concern and pose a significant obstacle to their use. This review discusses the pathogenic mechanisms by which the conventional acidic NSAIDs induce gastrointestinal toxicity, with particular emphasis on non-prostaglandin effects. Methods of assessment of NSAID-induced enteropathy are reviewed, with particular emphasis on the use of functional measurement of NSAID-induced changes in the gastrointestinal tract. The advances in our knowledge of the pathogenesis of these effects have resulted in the development of a range of novel NSAIDs. Where functional assessment of the effects of NSAIDs has been employed, it appears to be more useful as an indicator of early-stage changes rather than a predictor of the effects of long-term NSAID exposure. Successful pharmaceutical strategies now offer considerable promise for reducing the severity of NSAID damage to the gastrointestinal tract. The utility of intestinal permeability measurements for selection and assessment of these strategies is discussed. [source] The different fates of mitochondria and chloroplasts during dark-induced senescence in Arabidopsis leavesPLANT CELL & ENVIRONMENT, Issue 12 2007OLIVIER KEECH ABSTRACT Senescence is an active process allowing the reallocation of valuable nutrients from the senescing organ towards storage and/or growing tissues. Using Arabidopsis thaliana leaves from both whole darkened plants (DPs) and individually darkened leaves (IDLs), we investigated the fate of mitochondria and chloroplasts during dark-induced leaf senescence. Combining in vivo visualization of fates of the two organelles by three-dimensional reconstructions of abaxial parts of leaves with functional measurements of photosynthesis and respiration, we showed that the two experimental systems displayed major differences during 6 d of dark treatment. In whole DPs, organelles were largely retained in both epidermal and mesophyll cells. However, while the photosynthetic capacity was maintained, the capacity of mitochondrial respiration decreased. In contrast, IDLs showed a rapid decline in photosynthetic capacity while maintaining a high capacity for mitochondrial respiration throughout the treatment. In addition, we noticed an unequal degradation of organelles in the different cell types of the senescing leaf. From these data, we suggest that metabolism in leaves of the whole DPs enters a ,stand-by mode' to preserve the photosynthetic machinery for as long as possible. However, in IDLs, mitochondria actively provide energy and carbon skeletons for the degradation of cell constituents, facilitating the retrieval of nutrients. Finally, the heterogeneity of the degradation processes involved during senescence is discussed with regard to the fate of mitochondria and chloroplasts in the different cell types. [source] Monitoring of Cochlear Function During Cochlear ImplantationTHE LARYNGOSCOPE, Issue 6 2006Oliver Adunka MD Abstract Objective: To report the feasibility of monitoring cochlear function during cochlear implantation. Study Design: Case report. Setting: Tertiary care referral center. Methods: A child with audiologic features typical of bilateral auditory neuropathy underwent cochlear implantation. The scala tympani was entered inferior and slightly anterior to the round window membrane margin and smooth electrode insertion was achieved. Using single polarity click stimuli, the cochlear microphonic was measured at several steps during surgery. Results: Cochlear microphonics were present at all stages during the implantation process and were clearly distinguished from neural responses by stimulus polarity inversion and constant latencies, despite changes in stimulus level. With the electrode in situ, amplitudes were smaller but persisted until the final measurement at 10 minutes after insertion. At follow-up 2 weeks after surgery, behavioral audiometry results indicated profound hearing loss in the operated ear. Conclusions: This paper demonstrates the feasibility of monitoring cochlear function during cochlear implantation. The routine surgical approach did not appear to adversely affect the functional measurements. Standard size, full electrode insertion did diminish the amplitude of the cochlear microphonics, possibly as a result of intracochlear mechanical impairment. Ultimately, profound hearing loss was documented, indicating that factors other than immediate changes induced by electrode insertion were likely responsible for the loss of cochlear function. [source] | ||||||||||