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Functional Group Transformation (functional + group_transformation)

Distribution by Scientific Domains
Chemistry100%

Selected Abstracts

Functional Group Transformation of Perfluoroadamantane Derivatives.

CHEMINFORM, Issue 49 2006
Koichi Murata
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]

Realization of the Synthesis of ,,,-Disubstituted Carbamylacetates and Cyanoacetates by Either Enzymatic or Chemical Functional Group Transformation, Depending upon the Substrate Specificity of Rhodococcus Amidase.

CHEMINFORM, Issue 9 2005
Masahiro Yokoyama
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

Biotransformation of benzaldehyde to L -phenylacetylcarbinol (L -PAC) by Torulaspora delbrueckii and conversion to ephedrine by microwave radiation

JOURNAL OF CHEMICAL TECHNOLOGY & BIOTECHNOLOGY, Issue 2 2002
Vilas B Shukla
Abstract In a 5,dm3 stirred tank reactor, bioconversion of 30,g benzaldehyde by cells of Torulaspora delbrueckii yielded 22.9,g of pure L -phenylacetylcarbinol (L -PAC). Facile functional group transformation of 4.5,g of L -PAC to 2-(methylimino)-1-phenyl-1-propanol by exposure to microwave irradiation for 9,min resulted in 2.48,g of product. Conversion of 4.8,g of 2-(methylimino)-1-phenyl-1-propanol to 3.11,g of ephedrine was achieved by exposure to microwaves in a reaction time of 10,min. The identity of all the products was confirmed by 1H NMR and FT-IR analysis. © 2002 Society of Chemical Industry [source]

Stereoselective Construction of a Highly Functionalized Taxoid ABC-Ring System: the C2,C9 Oxa-Bridge Approach

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, Issue 19 2005
Sylvain Hamon
Abstract The goal of this investigation is to assemble the 20-carbon unit 1 of the taxoid diterpene skeleton with a high level of stereocontrol by means of a three-reaction sequence developed in this laboratory. The strategy involves seven C,C bond-forming operations together with eighteen functional group transformations, circumventing the stereoselectivity issue altogether. Furthermore, there is no isomer formation and hence no need for chromatographic separation. A temporary oxa-bridge (C2/C9) was used as a problem-solving approach. The key step in the planned sequence was based on achieving the last C,C bonding between C11 and C12, following a successful C11 functionalization. X-ray analyses of 8b, 17, 18, 19, 20, and 21, together with extensive use of 800 MHz 1H (200 MHz 13C) NMR spectra, support the suggested structures. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005) [source]