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Selected AbstractsThe "Swimmer's View" as Alternative When Lateral View Is Inadequate During Interlaminar Cervical Epidural Steroid InjectionsPAIN MEDICINE, Issue 5 2010Arjang Abbasi DO Abstract Objective., To present a technique that better visualizes the needle during interlaminar cervical epidural steroid injection (ICESI) in patients where the lateral view is inadequate. Design., Case report. Setting., Private group practice. Subject., A 57-year-old morbidly obese male presenting for ICESI for left neck and upper limb pain after a motor vehicle accident. Magnetic resonance imaging revealed left C6-7 herniated nucleus pulposis and C4-5 osteophytic disc-ridge complex. Electrodiagnostic evaluation revealed activity consistent with a left C7 radiculopathy. Intervention., Left C7-T1 ICESI. Needle was obscured in the lateral view by the patient's shoulders. Needle was made visible by positioning the patient for Swimmer's view. Results., Full resolution of symptoms without associated complications. Conclusions., Grave complications have been associated with ICESI necessitating impeccable and systematic technique with substantial knowledge of anatomy. Although injection at lower levels is advocated for safety concerns, the needle during lateral view may be obscured by the shoulders in some patients. The "Swimmer's View" position may be attempted when lateral view is insufficient to visualize needle during ICESI. [source] Clustering revealed in high-resolution simulations and visualization of multi-resolution features in fluid,particle modelsCONCURRENCY AND COMPUTATION: PRACTICE & EXPERIENCE, Issue 2 2003Krzysztof Boryczko Abstract Simulating natural phenomena at greater accuracy results in an explosive growth of data. Large-scale simulations with particles currently involve ensembles consisting of between 106 and 109 particles, which cover 105,106 time steps. Thus, the data files produced in a single run can reach from tens of gigabytes to hundreds of terabytes. This data bank allows one to reconstruct the spatio-temporal evolution of both the particle system as a whole and each particle separately. Realistically, for one to look at a large data set at full resolution at all times is not possible and, in fact, not necessary. We have developed an agglomerative clustering technique, based on the concept of a mutual nearest neighbor (MNN). This procedure can be easily adapted for efficient visualization of extremely large data sets from simulations with particles at various resolution levels. We present the parallel algorithm for MNN clustering and its timings on the IBM SP and SGI/Origin 3800 multiprocessor systems for up to 16 million fluid particles. The high efficiency obtained is mainly due to the similarity in the algorithmic structure of MNN clustering and particle methods. We show various examples drawn from MNN applications in visualization and analysis of the order of a few hundred gigabytes of data from discrete particle simulations, using dissipative particle dynamics and fluid particle models. Because data clustering is the first step in this concept extraction procedure, we may employ this clustering procedure to many other fields such as data mining, earthquake events and stellar populations in nebula clusters. Copyright © 2003 John Wiley & Sons, Ltd. [source] Two-level multiscale enrichment methodology for modeling of heterogeneous platesINTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN ENGINEERING, Issue 9 2009Caglar OskayArticle first published online: 15 JUN 200 Abstract A new two-level multiscale enrichment methodology for analysis of heterogeneous plates is presented. The enrichments are applied in the displacement and strain levels: the displacement field of a Reissner,Mindlin plate is enriched using the multiscale enrichment functions based on the partition of unity principle; the strain field is enriched using the mathematical homogenization theory. The proposed methodology is implemented for linear and failure analysis of brittle heterogeneous plates. The eigendeformation-based model reduction approach is employed to efficiently evaluate the non-linear processes in case of failure. The capabilities of the proposed methodology are verified against direct three-dimensional finite element models with full resolution of the microstructure. Copyright © 2009 John Wiley & Sons, Ltd. [source] Direct meso-scale simulations of fibres in turbulent liquid flowTHE CANADIAN JOURNAL OF CHEMICAL ENGINEERING, Issue 4 2010J. J. Derksen Abstract A procedure for direct, meso-scale simulations of flexible fibres immersed in liquid flow is introduced. The fibres are composed of chains of spherical particles connected through ball joints with the bending stiffness of the joints as a variable. The motion of the fibres and the liquid is two-way coupled with full resolution of the solid,liquid interface. First the simulation procedure is validated by means of an analytical solution for sphere doublets in zero-Reynolds simple shear flow. Subsequently we use the numerical method to study inertial flows with fibres, more specifically the interaction of a fibre with isotropic turbulence. Une procédure pour des simulations directes à la méso-échelle de fibres souples immergées dans la circulation de liquide est présentée. Les fibres sont composées de chaînes de particules sphériques reliées par des joints à rotule avec la rigidité à la flexion des joints comme variable. Le mouvement des fibres et du liquide est bidirectionnel avec une résolution intégrale de l'interface solide-liquide. D'abord, la procédure de simulation est validée au moyen d'une solution analytique pour les doublets de sphère dans un écoulement de cisaillement simple à nombre de Reynolds nul. Par la suite, nous utilisons la méthode numérique pour étudier les flux inertiels avec les fibres, plus précisément l'interaction d'une fibre avec la turbulence isotrope. [source] BS13 THE EFFECT OF ANTIBIOTIC TREATMENT OF INFLAMMATORY BREAST DISEASE ASSOCIATED WITH THE ISOLATION OF LIPOPHILIC CORYNEBACTERIAANZ JOURNAL OF SURGERY, Issue 2007A. M. Skinner Granulomatous mastitis is a rare benign condition effecting women of reproductive age and is most commonly treated surgically. It is an inflammatory disease of the breast associated with the isolation of intracellular lipophilic corynebacteria and has a course of chronicity with recurrences. Purpose , Our aim was to observe the clinical response and subsequent course of women diagnosed with granulomatous mastitis and treated by a long course of lipophilic antibiotics. We also recorded the concurrent requirement for surgical intervention. Methodology , The clinical course of seventeen women with inflammatory breast disease and microbiologic and histologic evidence of infection with Corynebacterium kroppenstedtii were prospectively followed. 11 received treatment with doxycycline (or clindamycin if breast feeding), 5 women received alternative antibiotics, and one patient received no antibiotics. Results , Among the 11 who received doxycycline, full resolution without surgery of disease was achieved in 9 women while another woman showed improvement at follow up, further surgical management was required by 2. All the five women who received alternative antibiotics also had surgery. They each had full resolution of disease at follow up. Further admissions were required by one woman. Conclusion , Optimal treatment for granulomatous mastitis is yet to be determined. We found promising results with a small group of young women who were treated with the lipophilic antibiotic doxycycline alone. These had resolution of disease without requiring surgical intervention. [source] Clinical diagnosis and treatment of suspected neuropathic pain in three dogsAUSTRALIAN VETERINARY JOURNAL, Issue 1-2 2009RG Cashmore Three dogs were referred to The Queen's Veterinary School Hospital at University of Cambridge for chronic behavioural or locomotor disorders associated with pain. All three had been unsuccessfully treated with conventional analgesics, including non-steroidal anti-inflammatory drugs, glucocorticoids and opiate agonists, prior to referral, with minimal or no response. They were investigated by neurological examination plus conventional ancillary diagnostic tests and therapeutic drug trials. Ruling out other causes of pain and applying previously well-described criteria, each case was diagnosed as consistent with neuropathic pain, a poorly recognised condition in domestic dogs. Treatment with the tricyclic antidepressant drug, amitriptyline, or the antiepileptic drug, gabapentin, resulted in either a dramatic improvement or full resolution of clinical signs in all cases. [source] | ||||||||||