Former

Distribution by Scientific Domains
Distribution within Life Sciences

Kinds of Former

  • stone former

  • Terms modified by Former

  • former approach
  • former arable land
  • former being
  • former case
  • former condition
  • former drinker
  • former editor
  • former group
  • former head
  • former opponent
  • former part
  • former partner
  • former patient
  • former smoker
  • former soviet republic
  • former soviet union
  • former species
  • former studies
  • former study
  • former user
  • former yugoslav republic

  • Selected Abstracts


    Agrifood Sector Liberalisation and the Rise of Supermarkets in Former State-controlled Economies: A Comparative Overview

    DEVELOPMENT POLICY REVIEW, Issue 5 2004
    Thomas Reardon
    Former state-controlled economies (FSCEs) have become the most important destination of global retail chain investments. These economies, which spread from North Africa, across Central and Eastern Europe, to East Asia, include more than one and a half billion consumers and a large share of the world's agricultural area and poor farmers. They have undergone an often radical transformation of their agrifood system over the past decade. The take-off of supermarkets in FSCEs started seriously in the mid-late 1990s, and is now moving fast. This article compares FSCE experience in the supermarket revolution and considers its implications for policy-makers and rural development practitioners. [source]


    Fixed Exchange Rates and Banking Crises: When Does the Former Prevent the Latter?

    ECONOMIC NOTES, Issue 3 2009
    Victoria Miller
    Because monetary policy is constrained in fixed exchange rate regimes, banks should expect fewer money-financed bailouts and therefore manage their risks more carefully when exchange rates are fixed than when they are flexible. It follows that we should observe fewer banking crises in countries with formal currency pegs. The 1990s however are littered with occurrences of banking crises in countries with fixed exchange rates. This paper asks whether banks in those countries could have adopted excess risk expecting money-financed bailouts or whether their pegs discouraged such moral hazard-type risks. [source]


    Girls with anorexia nervosa as young adults: Personality, self-esteem, and life satisfaction

    INTERNATIONAL JOURNAL OF EATING DISORDERS, Issue 4 2006
    Inger Halvorsen MD
    Abstract Objective: The current study evaluated personality, self-esteem, and life satisfaction in former patients with different outcomes of childhood and adolescent-onset anorexia nervosa (AN). Methods: Forty-four female patients with AN were assessed 8.5 ± SD 3.4 years after treatment start with a clinical interview and questionnaires including the Temperament and Character Inventory (TCI) and the Rosenberg Self-Esteem Scale. Self-esteem and general life satisfaction in former patients were compared with women in a large population study. Results: Former AN patients with no eating disorder and normal eating attitudes at follow-up (n = 21 [48%]) had similar TCI profiles and self-esteem as samples from normal populations, whereas participants with poorer outcome had significantly lower TCI Self Directedness, self-esteem, and life satisfaction scores. Life satisfaction was reduced in all outcome groups and was strongly associated with self-esteem. Conclusion: Personality, self-esteem, and life satisfaction varied significantly between outcome groups. The results indicate that young patients with AN with a good outcome may have normal personality and self-esteem features in young adulthood. © 2006 by Wiley Periodicals, Inc., Int J Eat Disord, 2006 [source]


    Antipsychotic drugs and short-term mortality after peptic ulcer perforation: a population-based cohort study

    ALIMENTARY PHARMACOLOGY & THERAPEUTICS, Issue 7 2008
    C. CHRISTIANSEN
    Summary Background, Peptic ulcer perforation is a serious surgical emergency with a substantial short-term mortality, but the influence of antipsychotic drug use on the prognosis remains unknown. Aim, To examine the association between antipsychotic drug use and 30-day mortality following peptic ulcer perforation. Methods, This cohort study comprised 2033 patients with a first-time hospitalization with peptic ulcer perforation, in Northern Denmark, between 1991 and 2004. Data on preadmission use of antipsychotics and other medications, psychiatric disease, other comorbidities and mortality were obtained through population-based medical databases. We used Cox regression analyses to compute adjusted mortality rate ratios (MRRs). Results, One hundred and sixteen (5.7%) patients with peptic ulcer perforation were current users of antipsychotic drugs at the time of hospital admission and 205 (10.1%) were former users. The overall 30-day mortality was 27%. Among current users of antipsychotics 30-day mortality was 39%. The adjusted 30-day MRR for current users of antipsychotic drugs compared with non-users was 1.7 (95% CI: 1.2,2.3). Former use was not a predictor of mortality. The increase in mortality was equal in users of conventional and atypical antipsychotics. Conclusion, Use of antipsychotic drugs is associated with substantially increased mortality following peptic ulcer perforation. [source]


    Oxidation and Volatilization of Silica Formers in Water Vapor

    JOURNAL OF THE AMERICAN CERAMIC SOCIETY, Issue 8 2003
    Elizabeth J. Opila
    At high temperatures, SiC and Si3N4 react with water vapor to form a SiO2 scale. SiO2 scales also react with water vapor to form a volatile Si(OH)4 species. These simultaneous reactions, one forming SiO2 and the other removing SiO2, are described by paralinear kinetics. A steady state, in which these reactions occur at the same rate, is eventually achieved. After steady state is achieved, the oxide found on the surface is a constant thickness, and recession of the underlying material occurs at a linear rate. The steady-state oxide thickness, the time to achieve steady state, and the steady-state recession rate can be described in terms of the rate constants for the oxidation and volatilization reactions. In addition, the oxide thickness, the time to achieve steady state, and the recession rate also can be determined from parameters that describe a water-vapor-containing environment. Accordingly, maps have been developed to show these steady-state conditions as a function of reaction rate constants, pressure, and gas velocity. These maps can be used to predict the behavior of SiO2 formers in water-vapor-containing environments, such as combustion environments. Finally, these maps are used to explore the limits of the paralinear oxidation model for SiC and Si3N4. [source]


    Automatic muscle generation for character skin deformation

    COMPUTER ANIMATION AND VIRTUAL WORLDS (PREV: JNL OF VISUALISATION & COMPUTER ANIMATION), Issue 3-4 2006
    Xiaosong Yang
    Abstract As skin shape depends on the underlying anatomical structure, the anatomy-based techniques usually afford greater realism than the traditional skeleton-driven approach. On the downside, however, it is against the current animation workflow, as the animator has to model many individual muscles before the final skin layer arrives, resulting in an unintuitive modelling process. In this paper, we present a new anatomy-based technique that allows the animator to start from an already modelled character. Muscles having visible influence on the skin shape at the rest pose are extracted automatically by studying the surface geometry of the skin. The extracted muscles are then used to deform the skin in areas where there exist complex deformations. The remaining skin areas, unaffected or hardly affected by the muscles, are handled by the skeleton-driven technique, allowing both techniques to play their strengths. In order for the extracted muscles to produce realistic local skin deformation during animation, muscle bulging and special movements are both represented. Whereas the former ensues volume preservation, the latter allows a muscle not only to deform along a straight path, but also to slide and bend around joints and bones, resulting in the production of sophisticated muscle movements and deformations. Copyright © 2006 John Wiley & Sons, Ltd. [source]


    Evaluation of Uncertainties Associated with Geocoding Techniques

    COMPUTER-AIDED CIVIL AND INFRASTRUCTURE ENGINEERING, Issue 3 2004
    Hassan A. Karimi
    Geocoded data play a major role in numerous engineering applications such as transportation and environmental studies where geospatial information systems (GIS) are used for spatial modeling and analysis as they contain spatial information (e.g., latitude and longitude) about objects. The information that a GIS produces is impacted by the quality of the geocoded data (e.g., coordinates) stored in its database. To make appropriate and reasonable decisions using geocoded data, it is important to understand the sources of uncertainty in geocoding. There are two major sources of uncertainty in geocoding, one related to the database that is used as a reference data set to geocode objects and one related to the interpolation technique used. Factors such as completeness, correctness, consistency, currency, and accuracy of the data in the reference database contribute to the uncertainty of the former whereas the specific logic and assumptions used in an interpolation technique contribute to the latter. The primary purpose of this article is to understand uncertainties associated with interpolation techniques used for geocoding. In doing so, three geocoding algorithms were used and tested and the results were compared with the data collected by the Global Positioning System (GPS). The result of the overall comparison indicated no significant differences between the three algorithms. [source]


    NMR and the uncertainty principle: How to and how not to interpret homogeneous line broadening and pulse nonselectivity.

    CONCEPTS IN MAGNETIC RESONANCE, Issue 5 2008
    IV. (Un?)certainty
    Abstract Following the treatments presented in Parts I, II, and III, I herein address the popular notion that the frequency of a monochromatic RF pulse as well as that of a monochromatic FID is "in effect" uncertain due to the (Heisenberg) Uncertainty Principle, which also manifests itself in the fact that the FT-spectrum of these temporal entities is spread over a nonzero frequency band. I will show that the frequency spread should not be interpreted as "in effect" meaning a range of physical driving RF fields in the former, and "spin frequencies" in the latter case. The fact that a shorter pulse or a more quickly decaying FID has a wider FT-spectrum is in fact solely due to the Fourier Uncertainty Principle, which is a less well known and easily misunderstood concept. A proper understanding of the Fourier Uncertainty Principle tells us that the FT-spectrum of a monochromatic pulse is not "broad" because of any "uncertainty" in the RF frequency, but because the spectrum profile carries all of the pulse's features (frequency, phase, amplitude, length, temporal location) coded into the complex amplitudes of the FT-spectrum's constituent eternal basis harmonic waves. A monochromatic RF pulse's capability to excite nonresonant magnetizations is in fact a purely classical off-resonance effect that has nothing to do with "uncertainty". Analogously, "Lorentzian lineshape" means exactly the same thing physically as "exponential decay," and all inferences as to the physical reasons for that decay must be based on independent assumptions or observations. © 2008 Wiley Periodicals, Inc. Concepts Magn Reson Part A 32A: 373,404, 2008. [source]


    Vascular endothelial growth factor in edematous mouse embryos induced by retinoic acid in utero

    CONGENITAL ANOMALIES, Issue 2 2001
    Yoshiko Yasuda
    ABSTRACT, Vascular endothelial growth factor (VEGF) is induced by hypoxic environment and contributes to vascular formation in both developing embryos and adults. Exogenous retinoic acid (RA) induces avascular yolk sacs with anemic stunted embryos of day 9 and 10 of gestation when RA is given to pregnant mice on day 6, 6.5 or 7 of pregnancy (Yasuda et al., 1996). We undertook the present studies to find out whether VEGF is activated and plays any role in those RA-exposed embryos. Embryos were obtained from dams given 60 mg/kg of RA on day 6 or 7 of pregnancy and sacrificed three days later. Most RA-exposed embryos showed edematous swelling without prominent vascular nets, but had beating heart tubes on day 9 and day 10 of gestation. Microscopic examination of developing tissue components showed various degrees of degeneration, and distension of the dorsal aorta when the body cavity was dosed. Northern blot analysis revealed expression of VEGF mRNA in the RA-exposed and control embryos. The highest expression of VEGF mRNA was seen in the embryos of day 10 exposed to RA on day 7, and these embryos had a significantly lower ATP content than did the controls (p < 0.01). Immunoreactive VEGF was detectable in both experimental and control embryos; in the former it was especially visible in the distended neuroepithelium, endothelium and membranes. These VEGF-immunoreactive regions also expressed another permeability factor, bradykinin. These findings suggest that VEGF upregulated by hypoxic conditions in edematous embryos induced by RA exposure in utero acts as hyperpermeability. [source]


    Eyelid dermatitis caused by an eyelash former

    CONTACT DERMATITIS, Issue 4 2005
    Ulrike Henke
    No abstract is available for this article. [source]


    Behaviour problems in childhood and adolescence in psychotic offenders: an exploratory study

    CRIMINAL BEHAVIOUR AND MENTAL HEALTH, Issue 3 2008
    Kris Goethals
    Background,Several studies have shown that adults who develop schizophrenia and commit a criminal offence may already have shown behaviour problems in childhood or adolescence. It is less clear whether such problems follow a particular pattern in such patients. Aims,To examine the utility of the Child Behavior Checklist (CBCL) among offenders, to test whether externalizing behaviour problems, as measured by the CBCL, are more frequent in psychotic offenders than in non-offenders with psychosis, and to investigate relationships between early behavioural problems and adult personality disorder in psychotic offenders. Methods,Three groups of violent offenders detained under the Dutch Entrustment Act (TBS-detainees)(n = 78) and one group of psychotic patients in general psychiatry (n = 16) were rated from case records on the CBCL. Results,There was a significant difference between psychotic offenders with a personality disorder (n = 25) and the non-offender patients with psychosis (n = 16) on the ,delinquent behavior' scale, but no such difference between psychotic offenders with (n = 25) and without (n = 21) personality disorder. A hierarchic cluster analysis revealed significantly higher scores for externalizing behaviour in all TBS-detainees with a personality disorder. Those starting to offend early had higher scores for externalizing behaviour than late starters. Conclusions,Psychotic and non-psychotic offenders with personality disorder resemble one another in their early childhood behaviour problems; psychotic offenders without a personality disorder differ from these two groups but resemble non-offenders with psychosis. In contrast to findings in non-forensic populations, there were no differences on other problem scales of the CBCL. Given the small sample sizes, replication is needed, but the findings lend weight to treatment models which focus on the psychosis in the latter two groups but extend also to personality disorder in the former. Copyright © 2008 John Wiley & Sons, Ltd. [source]


    Precursors and correlates of criminal behaviour in women

    CRIMINAL BEHAVIOUR AND MENTAL HEALTH, Issue 2 2004
    Dr Julie Messer
    Background The precursors and correlates of criminal behaviour in women were examined in this longitudinal study of women in their late thirties. Methods The sample consisted of a high-risk group of women (n = 86) and a comparison group ( n = 97): the former had been raised in institutional care. Questionnaire measures of childhood behaviour problems and detailed interview data from two time points in adulthood were obtained, along with official records of offending. Results In terms of childhood precursors, antisocial behaviour, institutional rearing, hyperactivity and adolescent conduct disorder were found to be significantly related to offending. Later adolescent factors were also found to be important: mixing with deviant peers and leaving school without any qualifications or plans for work. Correlates of offending in adulthood included difficulties in mental health, drug use, marriage and parenting. Further analysis was undertaken to clarify the associations by using ex-care status and conduct disorder as covariates. Discussion Well-established predictors of offending in male samples seem quite as important for women and girls. The findings also suggested strong links between offending and problems in parenting. Copyright © 2004 Whurr Publishers Ltd. [source]


    THE INTERACTION OF ANTISOCIAL PROPENSITY AND LIFE-COURSE VARYING PREDICTORS OF DELINQUENT BEHAVIOR: DIFFERENCES BY METHOD OF ESTIMATION AND IMPLICATIONS FOR THEORY,

    CRIMINOLOGY, Issue 2 2007
    GRAHAM C. OUSEY
    Recent criminological research has explored the extent to which stable propensity and life-course perspectives may be integrated to provide a more comprehensive explanation of variation in individual criminal offending. One line of these integrative efforts focuses on the ways that stable individual characteristics may interact with, or modify, the effects of life-course varying social factors. Given their consistency with the long-standing view that person,environment interactions contribute to variation in human social behavior, these theoretical integration attempts have great intuitive appeal. However, a review of past criminological research suggests that conceptual and empirical complexities have, so far, somewhat dampened the development of a coherent theoretical understanding of the nature of interaction effects between stable individual antisocial propensity and time-varying social variables. In this study, we outline and empirically assess several of the sometimes conflicting hypotheses regarding the ways that antisocial propensity moderates the influence of time-varying social factors on delinquent offending. Unlike some prior studies, however, we explicitly measure the interactive effects of stable antisocial propensity and time-varying measures of selected social variables on changes in delinquent offending. In addition, drawing on recent research that suggests that the relative ubiquity of interaction effects in past studies may be partly from the poorly suited application of linear statistical models to delinquency data, we alternatively test our interaction hypotheses using least-squares and tobit estimation frameworks. Our findings suggest that method of estimation matters, with interaction effects appearing readily in the former but not in the latter. The implications of these findings for future conceptual and empirical work on stable propensity/time-varying social variable interaction effects are discussed. [source]


    The ,II isotype of tubulin is present in the cell nuclei of a variety of cancers

    CYTOSKELETON, Issue 2 2004
    I-Tien Yeh
    Abstract Tubulin, the subunit protein of microtubules, has generally been thought to be exclusively a cytoplasmic protein in higher eukaryotes. We have previously shown that cultured rat kidney mesangial cells contain the ,II isotype of tubulin in their nuclei in the form of an ,,II dimer [Walss et al., 1999: Cell Motil. Cytoskeleton 42:274,284, 1999]. More recently, we examined a variety of cancerous and non-cancerous cell lines and found ,II in the nuclei of all of the former and only a few of the latter (Walss-Bass et al., 2002: Cell Tissue Res. 308:215,223]. In order to determine if ,II -tubulin occurs in the nuclei of actual cancers as well as in cancer cell lines, we used the immunoperoxidase method to look for nuclear ,II in a variety of tumors excised from 201 patients. We found that 75% of these tumors contain ,II in their nuclei. Distribution of nuclear ,II was highly dependent on the type of cancer, with 100% of the colon and prostate cancers, but only 19% of the skin tumors, having nuclear ,II. Nuclear ,II was particularly marked in tumors of epithelial origin, of which 83% showed nuclear ,II, in contrast to 54% in tumors of non-epithelial origin. In many cases, ,II staining occurred very strongly in the nuclei and not in the cytoplasm; in other cases, ,II was present in both. In many cases, particularly metastases, otherwise normal cells adjacent to the tumor also showed nuclear ,II, suggesting that cancer cells may influence nearby cells to synthesize ,II and localize it to their nuclei. Our results have implications for the diagnosis, biology, and chemotherapy of cancer. Cell Motil. Cytoskeleton 57:96,106, 2004. © 2004 Wiley-Liss, Inc. [source]


    Rationale for esthetic tissue preservation of a fresh extraction socket by an implant treatment concept simulating a tooth replantation

    DENTAL TRAUMATOLOGY, Issue 1 2010
    Georgia Trimpou
    A soft-tissue recession must be avoided, whether it is due to a compression of the peri-implant soft-tissue caused by an over-dimensioned restoration in the cervical collar of the provisional crown or to a too small dimensioned sulcus former. A simulation of the exact dimension of the lost tooth , especially on the cervical part of the new provisional restoration , is expected to preserve all relevant information and allows the design of a naturally looking emergence profile. Based on theoretical considerations and a case report, the authors intend to demonstrate that a near-naturally dimensioned sealing of the dento-gingival soft-tissue collar may initiate a tissue-maintaining healing process, similar to a tooth replantation. The natural dental crown, connected to an implant instead of the root, is applied for a tight sealing of the wound. If due to traumatic impact the tooth is no longer available, a naturally dimensioned crown restoration will serve as an alternative wound sealant. [source]


    Patterns of Detection of Superficial Spreading and Nodular-Type Melanoma: A Multicenter Italian Study

    DERMATOLOGIC SURGERY, Issue 11 2004
    Paolo Carli
    Background. Nodular histotype represents the condition that is mostly associated with diagnosis of thick melanoma. Objective. The objectives were to evaluate variables associated with and pattern of detection of nodular melanomas and to investigate variables associated with early diagnosis in accordance with histotype (nodular vs. superficial spreading melanomas). Methods. From the original data set of 816 melanomas, all the invasive lesions classified as superficial spreading (n=500) and nodular (n=93) melanomas were considered for the study. A multivariate logistic analysis was performed. Results. Nodular melanomas did not significantly differ from superficial spreading melanomas regarding sex, anatomic site, number of whole-body nevi, and the presence of atypical nevi. As expected, nodular melanomas were represented by a higher percentage of thick (>2 mm) lesions compared to superficial spreading melanomas (64.5% vs. 9.6%, p<0.001). The pattern of detection significantly differed between nodular and superficial spreading melanomas, the former being more frequently self-detected (44.1% vs. 38.0%) or detected by the family doctor (34.4% vs. 11.4%). Female sex, high level of education, and detection made by a dermatologist had an independent, protective effect against late (>1 mm in thickness) diagnosis in superficial spreading melanomas. No protective variable associated with nodular melanomas was found. Conclusion. Patterns of detection for nodular melanomas significantly differ from those for superficial spreading melanomas. For superficial spreading, but not for nodular, melanomas, variables associated with protective effect against late diagnosis can be identified. [source]


    Reproducibility evaluation of gross and net walking efficiency in children with cerebral palsy

    DEVELOPMENTAL MEDICINE & CHILD NEUROLOGY, Issue 1 2007
    Merel-Anne Brehm MSc
    In evaluating energy cost (EC) of walking, referred to as walking efficiency, the use of net measurement protocols (i.e. net=gross-resting) has recently been recommended. However, nothing is known about the comparative reproducibility of net protocols and the commonly used gross protocols. Ten minutes of resting and 5 minutes of walking at a self-selected speed were used to determine gross and net EC in 13 children with spastic cerebral palsy (CP; seven males, six females; mean age 8y 7mo [SD 3y 4mo], range 4y 1mo,13y) and in 10 children (three males, seven females) with typical development. In the former, their Gross Motor Function Classification System levels ranged from Level I to Level III; and seven had hemiplegia and six diplegia. There were four repeated sessions on different days, with periods of 1 week between sessions. Reproducibility was assessed for speed, and gross and net EC, by using the standard error of measurement. The results of this preliminary study showed that EC measurements were more variable for children with CP than for children with typical development. Furthermore, in both groups there was considerably more variability in the net measurements than in the gross measurements. We conclude that, on the basis of the methodology used, the use of gross EC, rather than net EC, seems a more sensitive measure of walking efficiency to detect clinically relevant changes in an individual child with CP. [source]


    Developmental profiles for multiple object tracking and spatial memory: typically developing preschoolers and people with Williams syndrome

    DEVELOPMENTAL SCIENCE, Issue 3 2010
    Kirsten O'Hearn
    The ability to track moving objects, a crucial skill for mature performance on everyday spatial tasks, has been hypothesized to require a specialized mechanism that may be available in infancy (i.e. indexes). Consistent with the idea of specialization, our previous work showed that object tracking was more impaired than a matched spatial memory task in individuals with Williams syndrome (WS), a genetic disorder characterized by severe visuo-spatial impairment. We now ask whether this unusual pattern of performance is a reflection of general immaturity or of true abnormality, possibly reflecting the atypical brain development in WS. To examine these two possibilities, we tested typically developing 3- and 4-year-olds and people with WS on multiple object tracking (MOT) and memory for static spatial location. The maximum number of objects that could be correctly tracked or remembered (estimated from the k -statistic) showed similar developmental profiles in typically developing 3- and 4-year-old children, but the WS profile differed from either age group. People with WS could track more objects than 3-year-olds, and the same number as 4-year-olds, but they could remember the locations of more static objects than both 3- and 4-year-olds. Combining these data with those from our previous studies, we found that typically developing children show increases in the number of objects they can track or remember between the ages of 3 and 6, and these increases grow in parallel across the two tasks. In contrast, object tracking in older children and adults with WS remains at the level of 4-year-olds, whereas the ability to remember multiple locations of static objects develops further. As a whole, the evidence suggests that MOT and memory for static location develop in tandem typically, but not in WS. Atypical development of the parietal lobe in people with WS could play a causal role in the abnormal, uneven pattern of performance in WS. This interpretation is consistent with the idea that multiple object tracking engages different mechanisms from those involved in memory for static object location, and that the former can be particularly disrupted by atypical development. [source]


    Diabetic neuropathy and oxidative stress

    DIABETES/METABOLISM: RESEARCH AND REVIEWS, Issue 4 2006
    Rodica Pop-Busui
    Abstract This review will focus on the impact of hyperglycemia-induced oxidative stress in the development of diabetes-related neural dysfunction. Oxidative stress occurs when the balance between the production of reactive oxygen species (ROS) and the ability of cells or tissues to detoxify the free radicals produced during metabolic activity is tilted in the favor of the former. Although hyperglycemia plays a key role in inducing oxidative stress in the diabetic nerve, the contribution of other factors, such as endoneurial hypoxia, transition metal imbalances, and hyperlipidemia have been also suggested. The possible sources for the overproduction of ROS in diabetes are widespread and include enzymatic pathways, auto-oxidation of glucose, and mitochondrial superoxide production. Increase in oxidative stress has clearly been shown to contribute to the pathology of neural and vascular dysfunction in diabetes. Potential therapies for preventing increased oxidative stress in diabetic nerve dysfunction will be discussed. Copyright © 2006 John Wiley & Sons, Ltd. [source]


    The value of the Rydel-Seiffer tuning fork as a predictor of diabetic polyneuropathy compared with a neurothesiometer

    DIABETIC MEDICINE, Issue 6 2004
    T. Kästenbauer
    Abstract Aims The aim of the study was to investigate the predictive value of the Rydel-Seiffer tuning fork for detecting diabetic neuropathy and to compare it with an electronic neurothesiometer. Methods In 2022 consecutive diabetic subjects, peripheral polyneuropathy was diagnosed by vibration perception threshold (VPT) at the tip of both great toes using a 128-Hz tuning fork and a neurothesiometer, by simple bedside tests and by the presence of neuropathic symptoms. These evaluations were further combined to diagnose peripheral nerve dysfunction (abnormal bedside tests) and symptomatic neuropathy. VPT was also measured in 175 non-diabetic control subjects to define normal values. Results VPT was normal in 1917 subjects and abnormal in 105 (5.2%) patients when measured by the tuning fork. Patients with an abnormal vibration test were significantly (P < 0.0001) older than subjects with a normal vibration sense, while diabetes duration and HbA1c of the former were also significantly elevated. The same was true for the percentages of an abnormal 10-g monofilament test (66.7% vs. 7.2%, P < 0.0001) and a missing Achilles' tendon reflex (68.6% vs. 24.8%, P < 0.0001). Finally, the VPT measured by the neurothesiometer was 2.5 times higher in patients with an abnormal tuning fork test (32.0 ± 9.8 vs. 12.5 ± 6.4 V, P < 0.0001). The plot of the difference of both methods against their mean yielded a good agreement of the two VPT measurements, and the tuning fork had a high sensitivity and positive predictive value for the diagnosis of abnormal bedside tests and for symptomatic neuropathy. Conclusion The tuning fork reliably detected peripheral neuropathy in comparison with the neurothesiometer. A tuning fork is a useful screening test for diabetic neuropathy. [source]


    Truth, Authenticity, and Rationality

    DIALECTICA, Issue 3 2007
    Ronald De Sousa
    Emotions are Janus-faced. They tell us something about the world, and they tell us something about ourselves. This suggests that we might speak of a truth, or perhaps two kinds of truths of emotions, one of which is about self and the other about conditions in the world. On some views, the latter comes by means of the former. Insofar as emotions manifest our inner life, however, we are more inclined to speak of authenticity rather than truth. What is the difference? We need to distinguish the criteria of correspondence or appropriateness suitable for authenticity from those that embody the criterion of truth. Furthermore there is also a question about the transitions , among states of mind, and between states of mind and behaviour , that emotions encourage. This realm of transitions concerns rationality. After sketching the relevant distinctions, I will endeavour to justify the view that emotions should be appraised in terms of all three terms. [source]


    Occurrence and distribution of sesamoid bones in squamates: a comparative approach

    ACTA ZOOLOGICA, Issue 3 2010
    Adriana Jerez
    Abstract Jerez, A., Mangione, S. and Abdala, V. 2010. Occurrence and distribution of sesamoid bones in squamates: a comparative approach.,Acta Zoologica (Stockholm) 91: 295,305 Sesamoids are defined as skeletal elements that develop within a continuous band of regular dense connective tissue (tendon or ligament) adjacent to an articulation or joint. In this work, we discuss developmental data on two squamate species, provide data on the onset of the squamate sesamoids and the muscles they are associated to. Our results show that Mabuya mabouya and Liolaemus albiceps exhibited rather similar ontogenetic patterns and that the first sesamoids appear in embryos. The ossifying sesamoid timing is different between M. mabouya and L. albiceps, being faster in the former. In adults, we found 41 sesamoids, considering both fore and hindlimbs. We did not find any intrataxonomic differences, or any differences between the right and left side of the specimens in relation to the sesamoid presence. We recognize four types of sesamoids: (1) embedded sesamoids; (2) interosseus sesamoids; (3) glide sesamoids; and (4) supporting sesamoids. A table is included with a preliminary survey of the sesamoid distribution pattern in 10 Squamate clades. [source]


    Esophageal motility changes after endoscopic intravariceal sclerotherapy with absolute alcohol

    DISEASES OF THE ESOPHAGUS, Issue 2 2000
    Ghoshal
    Endoscopic sclerotherapy (EST) leads to structural and motility changes in the esophagus; the former are thought to be commoner after EST with absolute alcohol (AA), which is a commonly used sclerosant in India as it is cheap and effective. There are no previous studies on changes in esophageal motility after EST with AA. Accordingly, we studied patients with portal hypertension before (n = 24) and after (n = 22) variceal obliteration by EST with AA using a water perfusion esophageal manometry system. Contraction amplitude in the distal esophagus was reduced in the post-EST group compared with the pre-EST group (63.4 ± 24.9 vs. 18.2 ± 14.3 mmHg, p < 0.01). Duration of esophageal contraction in both the proximal and distal esophagus became prolonged in the post-EST compared with the pre-EST group (3.3 ± 0.8 vs. 5.4 ± 2.6 and 4.3 ± 1.1 vs. 6.6 ± 2.3 s, p < 0.001 for both). Lower esophageal sphincter (LES) pressure was reduced in the post-EST compared with the pre-EST group, although the difference was not significant statistically. Abnormal contraction waveforms were more frequent in the post-EST group. One patient in the post-EST group had persistent dysphagia in the absence of endoscopically documented stricture at the time of manometric study. This study shows frequent occurrence of esophageal dysmotility after EST with AA; however, esophageal dysmotility after EST was infrequently associated with motor dysphagia. [source]


    Changes of traditional agrarian landscapes and their conservation implications: a case study of butterflies in Romania

    DIVERSITY AND DISTRIBUTIONS, Issue 6 2007
    Thomas Schmitt
    ABSTRACT Global biodiversity is decreasing as a result of human activities. In many parts of the world, this decrease is due to the destruction of natural habitats. The European perspective is different. Here, traditional agricultural landscapes developed into species-rich habitats. However, the European biodiversity heritage is strongly endangered. One of the countries where this biodiversity is best preserved is Romania. We analyse the possible changes in Romania's land-use patterns and their possible benefits and hazards with respect to biodiversity. As model group, we used butterflies, whose habitat requirements are well understood. We determined the ecological importance of different land-use types for the conservation of butterflies, underlining the special importance of Romania's semi-natural grasslands for nature conservation. We found that increasing modern agriculture and abandonment of less productive sites both affect biodiversity negatively , the former immediately and the latter after a lag phase of several years. These perspectives are discussed in the light of the integration of Romania into the European Union. [source]


    The role of mineralogy, geochemistry and grain size in badland development in Pisticci (Basilicata, southern Italy)

    EARTH SURFACE PROCESSES AND LANDFORMS, Issue 7 2007
    V. Summa
    Abstract Mineralogical, geochemical and grain-size composition of soil and pore-water chemistry parameters were characterized on both eroded (south-facing) and non-eroded (north-facing) clayey-silt slopes in the Basilicata region (southern Italy). Only a few grain-size parameters and clay mineralogy discriminate eroded from non-eroded substrates. Compared with the latter, the former have fractions of over 63 µm and 1,4 µm lower and fractions 4,63 µm higher. Grain-size characters of crusts did not discriminate with respect to substrate. Bulk rock mineralogy was not distinctive, but the clay mineral assemblage shows that the eroded slope is enriched in kaolinite, mixed layers (illite,smectite) and chlorite, whereas illite decreases, although overlaps are common. Chemical data enable discrimination between eroded and non-eroded slopes. pH, SAR (sodium adsorption ratio), TDS (total dissolved salts) and PS (percentage of sodium) are distinctive parameters for both eroded and non-eroded slopes. TDS increases in depth in the non-eroded slope, whereas the maximum TDS is just below the crust in the eroded one. On average, eroded substrates are higher in pH, SAR and PS than non-eroded ones. The ESP (exchangeable sodium percentage) of the eroded slope has a higher value than the non-eroded one. Crusts are less dispersive than eroded substrates, and non-eroded substrates behave as crusts. This suggests that the portion of the slope most severely exposed to weathering tends to stabilize, due to strong decreases in SAR, PS and ESP. Several diagrams reported in the literature show similarly anomalous crust samples on eroded slopes, compared with other samples coming from greater depths on eroded slopes. In the present case study, the exchangeable form of Na characterizes crusts more than the soluble form. This study describes the erosional mechanism, which involves morphological and geographic exposure and climatic elements, as well as grain size, mineralogy, chemistry and exchangeable processes of soils. Copyright © 2006 John Wiley & Sons, Ltd. [source]


    Testing bedload transport formulae using morphologic transport estimates and field data: lower Fraser River, British Columbia

    EARTH SURFACE PROCESSES AND LANDFORMS, Issue 10 2005
    Yvonne Martin
    Abstract Morphologic transport estimates available for a 65-km stretch of Fraser River over the period 1952,1999 provide a unique opportunity to evaluate the performance of bedload transport formulae for a large river over decadal time scales. Formulae tested in this paper include the original and rational versions of the Bagnold formula, the Meyer-Peter and Muller formula and a stream power correlation. The generalized approach adopted herein does not account for spatial variability in flow, bed structure and channel morphology. However, river managers and engineers, as well as those studying rivers within the context of long-term landscape change, may find this approach satisfactory as it has minimal data requirements and provides a level of process specification that may be commensurable with longer time scales. Hydraulic geometry equations for width and depth are defined using morphologic maps based on aerial photography and bathymetric survey data. Comparison of transport predictions with bedload transport measurements completed at Mission indicates that the original Bagnold formula most closely approximates the main trends in the field data. Sensitivity analyses are conducted to evaluate the impact of inaccuracies in input variables width, depth, slope and grain size on transport predictions. The formulae differ in their sensitivity to input variables and between reaches. Average annual bedload transport predictions for the four formulae show that they vary between each other as well as from the morphologic transport estimates. The original Bagnold and Meyer-Peter and Muller formulae provide the best transport predictions, although the former underestimates while the latter overestimates transport rates. Based on our findings, an error margin of up to an order of magnitude can be expected when adopting generalized approaches for the prediction of bedload transport. Copyright © 2005 John Wiley & Sons, Ltd. [source]


    The influence of parent material on topsoil geochemistry in eastern England

    EARTH SURFACE PROCESSES AND LANDFORMS, Issue 13 2003
    B. G. Rawlins
    Abstract The topsoil of around 10 000 km2 in eastern England has recently been sampled intensely at 4609 sites to characterize its geochemistry. The parent materials, which include both solid geology and Quaternary sediments, range in age from Permian to Holocene. The distributions of the concentrations of major and trace elements have been characterized geostatistically, and the role of parent material on their spatial structure (anisotropy) and their spatial relationships (coregionalization) have been investigated. Analysis of variance with the sites grouped by major parent material type showed that this classi,cation accounted for 14 to 48 per cent of the variance for the various elements. Global variograms of 13 elements (Al, As, Ca, Cr, Cu, Fe, Mg, Mo, Ni, P, Pb, Ti, and U) have been computed and modelled. Eleven of the variograms seem to comprise two structures, both of which we modelled with spherical functions, one of short range, 3·5 to 9 km, and the other with a range of 15 to 23 km. The models included a nugget variance, which varied from 27 per cent (for As, Fe, and Mg) to 63 per cent (for P) of the total. The long-range structures are related to the separations of the major parent materials. The variograms of several elements showed appreciable anisotropy, most notably that of Mg. Anisotropy is evident at short ranges of less than 5 km. This accords with the geological structure of the beds which dip from west to east so that their outcrops are elongated from north to south. A linear model of coregionalization ,tted to the data emphasized several important geochemical associations, which we interpret. Elements commonly associated with clay minerals (Mg, Al) and the clay size fraction (Ti) are dominated by the long-range structure of the coregionalization, whilst several trace elements (As, Cr, Ni and U) are spatially correlated with Fe over short distances, through adsorption of the former on the surfaces of Fe oxyhydroxides. The topsoil around large urban areas is enriched in lead, but it is not clear whether anthropogenic sources are responsible for this metal's anomalous spatial relationships with other elements. Crown copyright © 2003. Reproduced with the permission of Her Majesty's Stationery Of,ce. Published by John Wiley & Sons, Ltd. [source]


    In-situ gamma-ray spectrometric study of weathered volcanic rocks in Hong Kong

    EARTH SURFACE PROCESSES AND LANDFORMS, Issue 6 2002
    Margie Q. F. Chen
    Abstract In-situ gamma-ray spectrometry (GRS) measurements were conducted at 35 sites in Hong Kong where volcanic rocks with varying extent of weathering were exposed. Elemental analyses using X-ray fluorescence spectrometry and inductively coupled plasma,mass spectrometry were carried out on samples collected from these 35 plus 22 other locations to assess the feasibility of using the GRS method to quantify the extent of weathering. The Parker weathering index, varying within a range of 0·0,0·8 for the samples studied, was used as a geochemically based reference scheme for correlating the gamma-ray spectrometric results with the extent of weathering. For the former 35 sites, the concentrations of the three major radioelements, K, U and Th, determined by in-situ GRS were compared to laboratory-determined values from the samples. The study reveals that no significant change occurs to the contents of the three radioelements during the initial state of weathering. But once the rocks become highly weathered, further progression of weathering is accompanied by a systematic removal of K and an increased dispersion of U and Th. The results show that K content, which is indicative of the extent of weathering, can be retrieved reliably with the gamma-ray spectrometry technique. The study has given support to the potential use of the downhole spectral gamma method for evaluation of weathering grade and the detection of subsurface clay-rich levels. Copyright © 2002 John Wiley & Sons, Ltd. [source]


    Gully-head erosion processes on a semi-arid valley floor in Kenya: a case study into temporal variation and sediment budgeting

    EARTH SURFACE PROCESSES AND LANDFORMS, Issue 9 2001
    D. J. Oostwoud Wijdenes
    Abstract A three year monitoring programme of gully-head retreat was established to assess the significance of sediment production in a drainage network that expanded rapidly by gully-head erosion on the low-angled alluvio-lacustrine Njemps Flats in semi-arid Baringo District, Kenya. This paper discusses the factors controlling the large observed spatial and temporal variation in gully-head retreat rates, ranging from 0 to 15 m a,1. The selected gullies differed in planform and in runoff-contributing catchment area but soil material and land use were similar. The data were analysed at event and annual timescales. The results show that at annual timescale rainfall amount appears to be a good indicator of gully-head retreat, while at storm-event timescale rainfall distribution has to be taken into account. A model is proposed, including only rainfall (P) and the number of dry days (DD) between storms: which explains 56 per cent of the variation in retreat rate of the single-headed gully of Lam1. A detailed sediment budget has been established for Lam1 and its runoff-contributing area (RCA). By measuring sediment input from the RCA, the sediment output by channelized flow and linear retreat of the gully head for nine storms, it can be seen that erosion shifts between different components of the budget depending on the duration of the dry period (DD) between storms. Sediment input from the RCA was usually the largest component for the smaller storms. The erosion of the gully head occurred as a direct effect of runoff falling over the edge (GHwaterfall) and of the indirect destabilization of the adjacent walls by the waterfall erosion and by saturation (GHmass/storage). The latter component (GHmass/storage) was usually much larger that the former (GHwaterfall). The sediment output from the gully was strongly related to the runoff volume while the linear retreat, because of its complex behaviour, was not. Overall, the results show that the annual retreat is the optimal timescale to predict retreat patterns. More detailed knowledge about relevant processes and interactions is necessary if gully-head erosion is to be included in event-based soil erosion models. Copyright © 2001 John Wiley & Sons, Ltd. [source]


    Estimation of seismic drift and ductility demands in planar regular X-braced steel frames

    EARTHQUAKE ENGINEERING AND STRUCTURAL DYNAMICS, Issue 15 2007
    Theodore L. Karavasilis
    Abstract This paper summarizes the results of an extensive study on the inelastic seismic response of X-braced steel buildings. More than 100 regular multi-storey tension-compression X-braced steel frames are subjected to an ensemble of 30 ordinary (i.e. without near fault effects) ground motions. The records are scaled to different intensities in order to drive the structures to different levels of inelastic deformation. The statistical analysis of the created response databank indicates that the number of stories, period of vibration, brace slenderness ratio and column stiffness strongly influence the amplitude and heightwise distribution of inelastic deformation. Nonlinear regression analysis is employed in order to derive simple formulae which reflect the aforementioned influences and offer a direct estimation of drift and ductility demands. The uncertainty of this estimation due to the record-to-record variability is discussed in detail. More specifically, given the strength (or behaviour) reduction factor, the proposed formulae provide reliable estimates of the maximum roof displacement, the maximum interstorey drift ratio and the maximum cyclic ductility of the diagonals along the height of the structure. The strength reduction factor refers to the point of the first buckling of the diagonals in the building and thus, pushover analysis and estimation of the overstrength factor are not required. This design-oriented feature enables both the rapid seismic assessment of existing structures and the direct deformation-controlled seismic design of new ones. A comparison of the proposed method with the procedures adopted in current seismic design codes reveals the accuracy and efficiency of the former. Copyright © 2007 John Wiley & Sons, Ltd. [source]