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Follow-up Testing (follow-up + testing)
Selected AbstractsPersonality Trait Profiles of Missionary AdolescentsJOURNAL OF TRAVEL MEDICINE, Issue 6 2000Terry L. Dwelle Background: The study objective was to compare the Taylor-Johnson Temperament Analysis secondary population norms for adolescents, to test results of Assemblies of God missionary adolescents, and determine if the mission's experience had significant impact on personality traits. Methods: A retrospective record review study of Taylor-Johnson Temperament Analysis test results administered to all missionary adolescents aged 13- to 18-years-old, having attended a yearly school of missions from 1986 to 1994, was performed. A two-sample, two-tailed t -test was used for statistical analysis. Test results were compared with standard adolescent and adult norms. Initial, and second test results when available, were compared for significant personality trait changes in adolescents over a 2,3 year interval, while in the mission's program. Subpopulation norms were calculated for the study group. Results: Initial tests from 438 study group adolescents demonstrated significant differences in 7 of 9 personality trait categories for males, and 8 of 9 for females, compared with test adolescent norms. Initial, and second test comparisons were performed in 67 adolescents, and showed no significant changes in the personality trait scores in males and females. Personality trait profiles for females more closely resembled adult than adolescent norms, with 8 of the 9 personality trait categories showing no significant difference between adult female norms and study females. Conclusions: Clinicians and mission's sending agencies should be aware of the unique Taylor-Johnson Temperament Analysis test patterns for missionary adolescents, and that Taylor-Johnson Temperament Analysis norm tables for adolescents seem inadequate in evaluating missionary adolescents. Appropriate subpopulation norms are likely necessary. The impact of missions on personality trait categories of missionary adolescents seems negligible, but needs further research with methods that assure follow-up testing. These considerations could apply to other subpopulations and psychological tests. [source] Integrating Formal and Functional Approaches to Language Teaching in French Immersion: An Experimental StudyLANGUAGE LEARNING, Issue 2001Elaine M. Day This experimental study was designed to evaluate the effect on French language proficiency of an integrated formal, analytic and functional, communicative approach (experiential) to second-language teaching in the immersion classroom. The impetus for the study arises from previous research indicating that immersion children show persistent weaknesses in their grammatical skills despite the fluent, functional proficiency they achieve in their second language. The experimental materials, which were custom-designed for our study, highlight form-function relations, promote noticing, encourage metalin-guistic awareness, and provide opportunities for language practice and thus relate to some of the theoretical issues that Rod Ellis (this volume) has indicated are important in SLA in the 90s. This classroom-based study on the conditional is one of a series of studies undertaken in Canadian French immersion to investigate the effectiveness of form-focused instruction in classrooms (see Swain, 2000). The results of our study, which was conducted in grade 7 early immersion, showed that the Experimental group performed significantly higher in writing than the Control group, in both the post- and the follow-up testing. Although this was not found for speaking, an examination of the individual class data revealed greater and more consistent growth in speaking for the Experimental than for the Control classes, suggesting that they benefited somewhat from the experi- mental treatment in this domain as well. Although Ellis (this volume) notes that research on form-focused instruc- tion in the 90s has tended to split pedagogy from theory, the immersion research in this area does not seem t o reflect this shift. In a recent article, Swain (2000) reviews the French Immersion (FI) studies and summarizes their re- sults as follows: "Overall, the set of experiments conducted in FI classes suggest that there is value in focusing on language form through the use of pre-planned curriculum materials in the context of content-based language learn- ing" (Swain, 2000, p. 205). Her reference to curriculum materials and to the specific context of content-based lan- guage learning should signal to the reader the orientation t o pedagogical considerations that characterize this research. As Ellis notes, hybrid research using both experimental and qualitative methods is becoming more common in SLA. Recently, the experimental materials in our study were implemented in a grade 8 immersion classroom, and the children's collaborative language activity was observed by a researcher working from a sociocultural theoretical per- spective (Spielman-Davidson, 2000). The uptake of our research by a researcher working in another paradigm introduces another kind of hybridity that we hope will also shed further light on questions in form-focused instruction and lead to appropriate changes in pedagogy and in the design of immersion curricula. [source] Kinetics and sensitivity of ELISA IgG pertussis antitoxin after infection and vaccination with Bordetella pertussis in young childrenAPMIS, Issue 11 2009HANS O. HALLANDER Sera from 96 young children in a vaccine trial were analysed for kinetics of ELISA IgG anti-pertussis toxin (anti-PT) after a laboratory-verified pertussis infection. The antibody decay curves after infection were biphasic and similar in shape to those after vaccination. The change from a rapid to a slower decay after the peak occurred about 4,5 months from the first day of cough. In a group of children given a two- or a five-component acellular pertussis vaccine the proportion of sera above the tentative cut-off values for anti-PT of 20, 50 or 100 EU/ml 12 months after onset of the infection were 19%, 0% and 0% respectively. Corresponding figures for a whole-cell or placebo vaccine group of infected children were significantly higher, 73%, 39% and 30%, i.e. the antibody decay after infection in young children depends on vaccination status as well as on the pertussis vaccine given. In a large group of non-infected children vaccinated with the same five-component acellular vaccine 13%, 0% and 0% had sera above 20, 50 and 100 EU/ml at 12 months after the third vaccine dose and all were below the minimum level of detection 2 years after vaccination. In conclusion, knowledge about anti-PT kinetics is essential for the interpretation of seroepidemiological data but hardly offers the possibility to establish valid cut-off values for anti-PT in single sample serology. An option would be to identify a grey zone between the positive and negative ends of the distribution for follow-up testing by a second serum. [source] Detection of Undiagnosed Diabetes and Prediabetic States in High-risk Emergency Department PatientsACADEMIC EMERGENCY MEDICINE, Issue 5 2009Michelle A. Charfen MD Abstract Background:, Diabetes is often not diagnosed until complications appear, and one-third of those with diabetes may be undiagnosed. Prediabetes and diabetes are conditions in which early detection would be appropriate, because the duration of hyperglycemia is a predictor of adverse outcomes, and there are effective interventions to prevent disease progression and to reduce complications. Objectives:, The objectives were to determine the prevalence of diabetes mellitus and prediabetes in emergency department (ED) patients with an elevated random glucose or risk factors for diabetes but without previously diagnosed diabetes and to identify which at-risk ED patients should be considered for referral for confirmatory diagnostic testing. Methods:, This two-part study was composed of a prospective 2-year cohort study, and a 1-week cross-sectional survey substudy, set in an urban ED in Los Angeles County, California. A convenience sample was enrolled of 528 ED patients without previously diagnosed diabetes with either 1) a random serum glucose , 140 mg/dL regardless of the time of last food intake or a random serum glucose , 126 mg/dL if more than 2 hours since last food intake or 2) at least two predefined diabetes risk factors. Measurements included presence of diabetes risk factors, ED glucose, cortisol, insulin and glycosylated hemoglobin (HbA1c), and 2-hour oral glucose tolerance test results, administered at 6-week follow-up. Results:, Glycemic status was confirmed at follow-up in 256 (48%) of the 528 patients. Twenty-seven (11%) were found to have diabetes, 141 (55%) had prediabetes, and 88 (34%) had normal results. Age, ED glucose, HbA1c, cortisol, and random serum glucose , 140 mg/dL were associated with both diabetes and prediabetes on univariate analysis. A random serum glucose , 126 mg/dL after 2 hours of fasting was associated with diabetes but not prediabetes; ED cortisol, insulin, age , 45 years, race, and calculated body mass index (BMI) were associated with prediabetes but not diabetes. In multivariable models, among factors measurable in the ED, the only independent predictor of diabetes was ED glucose, while ED glucose, age , 45 years, and symptoms of polyuria and polydipsia were independent predictors of prediabetes. All at-risk subjects with a random ED blood glucose > 155 mg/dL had either prediabetes or diabetes on follow-up testing. Conclusions:, A substantial fraction of this urban ED study population was at risk for undiagnosed diabetes and prediabetes, and among the at-risk patients referred for follow-up, the majority demonstrated diabetes or prediabetes. Notably, all patients with two risk factors and a random serum glucose > 155 mg/dL were later diagnosed with prediabetes or diabetes. Consideration should be given to referring ED patients with risk factors and a random glucose > 155 mg/dL for follow-up testing. [source] Postnatal testing for diabetes in Australian women following gestational diabetes mellitusAUSTRALIAN AND NEW ZEALAND JOURNAL OF OBSTETRICS AND GYNAECOLOGY, Issue 5 2009Melinda K. MORRISON Background:, Postnatal blood glucose testing is recommended for reclassification of glucose tolerance following a pregnancy affected by gestational diabetes mellitus (GDM); however, there are limited data on the postnatal follow-up sought by Australian women. Aims:, To describe postnatal diabetes testing patterns in Australian women following a pregnancy affected by GDM and identify factors associated with return for follow-up testing in accordance with the Australasian Diabetes in Pregnancy Society (ADIPS) guidelines. Methods:, A cross-sectional self-administered survey of 1372 women diagnosed with GDM between 2003 and 2005, sampled from the National Diabetes Services Scheme database. Results:, Postnatal diabetes testing was reported by 73.2% of survey respondents with 27.4% returning for an oral glucose test tolerance at six to eight weeks post-GDM pregnancy. Using logistic regression analysis, factors associated with appropriate postnatal testing were receiving individualised risk reduction advice (odds ratio (OR) 1.41 (1.08,1.84)) or written information (OR 1.35 (1.03,1.76)) and in two-way interactions, being under the care of an endocrinologist and not tertiary educated (OR 2.09 (1.49,2.93)) as well as seeing an obstetrician and diabetes educator during pregnancy (OR 1.72 (1.19,2.48)). Every five years increase in age reduced the likelihood of a woman returning for testing by 17%. Conclusions:, Specialist diabetes care in non-tertiary educated women, or a team approach to management with diabetes education and obstetric care may act to reinforce the need for postnatal diabetes testing in accordance with the ADIPS guidelines. Individualised follow up from a health professional and provision of written information following a GDM pregnancy may also encourage return for postnatal testing in this high-risk group. [source] An artificial neural network for five different assay systems of prostate-specific antigen in prostate cancer diagnosticsBJU INTERNATIONAL, Issue 7 2008Carsten Stephan OBJECTIVE To compare separate prostate-specific antigen (PSA) assay-specific artificial neural networks (ANN) for discrimination between patients with prostate cancer (PCa) and no evidence of malignancy (NEM). PATIENTS AND METHODS In 780 patients (455 with PCa, 325 with NEM) we measured total PSA (tPSA) and free PSA (fPSA) with five different assays: from Abbott (AxSYM), Beckman Coulter (Access), DPC (Immulite 2000), and Roche (Elecsys 2010) and with tPSA and complexed PSA (cPSA) assays from Bayer (ADVIA Centaur). ANN models were developed with five input factors: tPSA, percentage free/total PSA (%fPSA), age, prostate volume and digital rectal examination status for each assay separately to examine two tPSA ranges of 0,10 and 10,27 ng/mL. RESULTS Compared with the median tPSA concentrations (range from 4.9 [Bayer] to 6.11 ng/mL [DPC]) and especially the median %fPSA values (range from 11.2 [DPC] to 17.4%[Abbott], for tPSA 0,10 ng/mL), the areas under the receiver operating characteristic curves (AUC) for all calculated ANN models did not significantly differ from each other. The AUC were: 0.894 (Abbott), 0.89 (Bayer), 0.895 (Beckman), 0.882 (DPC) and 0.892 (Roche). At 95% sensitivity the specificities were without significant differences, whereas the individual absolute ANN outputs differed markedly. CONCLUSIONS Despite only slight differences, PSA assay-specific ANN models should be used to optimize the ANN outcome to reduce the number of unnecessary prostate biopsies. We further developed the ANN named ,ProstataClass' to provide clinicians with an easy to use tool in making their decision about follow-up testing. [source] | ||||||||||