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Four-Component Reaction (four-component + reaction)

Distribution by Scientific Domains
Chemistry100%

Selected Abstracts

One-Pot Synthesis of Tetraalkyl Benzene-1,2,3,5-tetracarboxylates from a Four-Component Reaction of Alkyl Propiolates and Alkyl 2-Nitroethanoates Promoted by Ph3P

HELVETICA CHIMICA ACTA, Issue 12 2006
Issa Yavari
Abstract Alkyl 2-nitroethanoates react with alkyl propiolates in the presence of triphenylphosphine (Ph3P) in a mechanistically unprecedented reaction to afford tetraalkyl benzene-1,2,3,5-tetracarboxylates in moderate yields (36,42%). [source]

ChemInform Abstract: A Facile Route to ,-Nitro Imidates via Four-Component Reaction of Alkynes with Sulfonyl Azides, Alcohols, and Nitroolefins.

CHEMINFORM, Issue 38 2010
Wangze Song
No abstract is available for this article. [source]

ChemInform Abstract: Multicatalytic Synthesis of 1,2-Dihydroisoquinolin-1-ylphosphonates via a Tandem Four-Component Reaction.

CHEMINFORM, Issue 47 2009
Haibo Zhou
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

ChemInform Abstract: Four-Component Reaction of Isocyanides, Acetylenic Esters, and Carboxylic Acids for the Synthesis of Functionalized 2,5-Diaminofurans.

CHEMINFORM, Issue 44 2009
Mohammad Anary-Abbasinejad
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

ChemInform Abstract: Synthesis of Fully Substituted Pyrazolo[3,4-b]pyridine-5-carboxamide Derivatives via a One-Pot Four-Component Reaction.

CHEMINFORM, Issue 39 2009
Ahmad Shaabani
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

ChemInform Abstract: Novel Isocyanide-Based Four-Component Reaction: A Facile Synthesis of Fully Substituted 3,4-Dihydrocoumarin Derivatives.

CHEMINFORM, Issue 45 2008
Ahmad Shaabani
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

ChemInform Abstract: Diastereoselective Synthesis of ,-Lactams by a One-Pot, Four-Component Reaction.

CHEMINFORM, Issue 13 2008
Jingqiang Wei
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a "Full Text" option. The original article is trackable via the "References" option. [source]

One-Pot Synthesis of Functionalized Hydantoin Derivatives via a Four-Component Reaction Between an Amine, an Arylsulfonyl Isocyanate and an Alkyl Propiolate or Dialkyl Acetylenedicarboxylate in the Presence of Triphenylphosphine.

CHEMINFORM, Issue 42 2007
Abdolali Alizadeh
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]

Rapid Access to Oxindoles by the Combined Use of an Ugi Four-Component Reaction and a Microwave-Assisted Intramolecular Buchwald,Hartwig Amidation Reaction.

CHEMINFORM, Issue 4 2007
Florence Bonnaterre
Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF. [source]

A Novel Pseudo Four-Component Reaction: Unexpected Formation of Densely Functionalized Pyrroles.

CHEMINFORM, Issue 7 2005
Ahmad Shaabani
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

Liquid-Phase Combinatorial Synthesis of Alicyclic ,-Lactams via Ugi Four-Component Reaction.

CHEMINFORM, Issue 42 2002
Szilvia Gedey
Abstract For Abstract see ChemInform Abstract in Full Text. [source]

Byproduct-Catalyzed Four-Component Reactions of Aldehydes with Hexamethyldisilazane, Chloroformates, and Nucleophiles in Acetonitrile Leading to Protected Primary Amines, ,-Amino Esters, and ,-Amino Ketones

CHEMISTRY - A EUROPEAN JOURNAL, Issue 2 2010
Bai-Ling Yang
Abstract Multicomponent reactions are a very powerful tool for the construction of complex organic molecules by using readily available starting materials. While most of the multicomponent reactions discovered so far consist of three components, the reactions with four or more components remain sparse. We have successfully developed several four-component reactions using a catalytic amount of water as a hydrolyzing agent to decompose byproduct chlorotrimethylsilane (TMSCl) to yield secondary byproduct HCl that serves as a catalyst. In the presence of 40,mol,% of water, the four-component reaction of aldehydes with hexamethyldisilazane (HMDS), chloroformates, and silylated nucleophiles proceeds smoothly at room temperature to give a range of protected primary amines in moderate to excellent yields. Importantly, a wide variety of protic carbon nucleophiles, such as ,-keto esters, ,-diketones, and ketones, have further been explored as suitable substrates for the synthesis of protected ,-amino esters and ,-amino ketones that are useful building blocks for various pharmaceuticals and natural products. These four-component reactions proceed through a pathway of tandem nitrogen protection/imine formation/imine addition, and the decomposition of byproduct TMSCl, generated in the first step of nitrogen protection, with water results in the formation of secondary byproduct HCl, a strong Brønsted acid that catalyzes the following imine formation/imine addition. Taking advantage of the fact that alcohols or phenols are also able to decompose byproduct TMSCl to yield secondary byproduct HCl, no catalyst is needed at all for the four-component reactions with aldehydes bearing hydroxy groups. [source]