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Flow Requirements (flow + requirement)
Selected AbstractsMyocardial Perfusion As Assessed by Positron Emission Tomography During Long-Term Mechanical Circulatory SupportCONGESTIVE HEART FAILURE, Issue 2 2006George V. Letsou MD Although mechanical circulatory support (MCS) can improve myocardial function in patients with advanced heart failure, its effects on relative myocardial perfusion are unclear. Using positron emission tomographic imaging techniques, the authors assessed relative myocardial perfusion in patients with ischemic or idiopathic cardiomyopathy who were receiving chronic MCS with a left ventricular assist device (pulsatile HeartMate [n=2] [Thoratec Corporation, Pleasanton, CA] or nonpulsatile Jarvik 2000 [n=4] [Jarvik Heart, Inc., New York, NY]). Relative myocardial perfusion was compared at lower and higher levels of MCS (50 vs. 100,110 ejections/min for the HeartMate and 8000 vs. 12,000 rpm for the Jarvik 2000). The size and severity of perfusion defects at rest and after dipyridamole stress were measured objectively and subjectively by computer algorithms and visual inspection, respectively. Relative myocardial perfusion increased >5% from baseline in only one of six patients when MCS was increased. No change in relative myocardial perfusion of >5% was seen in any of the other five patients, even after subsequent dipyridamole stress positron emission tomographic imaging. These pilot study findings suggest that the decreased metabolic requirements induced by ventricular unloading correspondingly decreased blood flow requirements to physiologically inactive myocardium. [source] Adaptive management of an environmental watering event to enhance native fish spawning and recruitmentFRESHWATER BIOLOGY, Issue 1 2010A. J. KING Summary 1. A common goal of many environmental flow regimes is to maintain and/or enhance the river's native fish community by increasing the occurrence of successful spawning and recruitment events. However, our understanding of the flow requirements of the early life history of fish is often limited, and hence predicting their response to specific managed flow events is difficult. To overcome this uncertainty requires the use of adaptive management principles in the design, implementation, monitoring and adjustment of environmental flow regimes. 2. The Barmah-Millewa Forest, a large river red gum forest on the Murray River floodplain, south-east Australia, contains a wide variety of ephemeral and permanent aquatic habitats suitable for fish. Flow regulation of the Murray River has significantly altered the natural flood regime of the Forest. In an attempt to alleviate some of the effects of river regulation, the Forest's water regime is highly managed using a variety of flow control structures and also receives targeted Environmental Water Allocations (EWA). In 2005, the largest environmental flow allocated to date in Australia was delivered at the Forest. 3. This study describes the adaptive management approach employed during the delivery of the 2005 EWA, which successfully achieved multiple ecological goals including enhanced native fish spawning and recruitment. Intensive monitoring of fish spawning and recruitment provided invaluable real-time and ongoing management input for optimising the delivery of environmental water to maximise ecological benefits at Barmah-Millewa Forest and other similar wetlands in the Murray-Darling Basin. 4. We discuss possible scenarios for the future application of environmental water and the need for environmental flow events and regimes to be conducted as rigorous, large-scale experiments within an adaptive management framework. [source] Climatic influences and anthropogenic stressors: an integrated framework for streamflow management in Mediterranean-climate California, U.S.A.FRESHWATER BIOLOGY, Issue 2010THEODORE E. GRANTHAM Summary 1. In Mediterranean and other water-stressed climates, water management is critical to the conservation of freshwater ecosystems. To secure and maintain water allocations for the environment, integrated water management approaches are needed that consider ecosystem flow requirements, patterns of human water demands and the temporal and spatial dynamics of water availability. 2. Human settlements in Mediterranean climates have constructed water storage and conveyance projects at a scale and level of complexity far exceeding those in other, less seasonal climates. As a result, multiple ecological stressors associated with natural periods of flooding and drying are compounded by anthropogenic impacts resulting from water infrastructure development. 3. Despite substantial investments in freshwater ecosystem conservation, particularly in California, U.S.A., success has been limited because the scales at which river management and restoration are implemented are often discordant with the temporal and spatial scales at which ecosystem processes operate. Often, there is also strong social and political resistance to restricting water allocation to existing consumptive uses for environmental protection purposes. Furthermore, institutions rarely have the capacity to develop and implement integrated management programmes needed for freshwater ecosystem conservation. 4. We propose an integrated framework for streamflow management that explicitly considers the temporal and spatial dynamics of water supply and needs of both human and natural systems. This approach makes it possible to assess the effects of alternative management strategies to human water security and ecosystem conditions and facilitates integrated decision-making by water management institutions. 5. We illustrate the framework by applying a GIS-based hydrologic model in a Mediterranean-climate watershed in Sonoma County, California, U.S.A. The model is designed to assess the hydrologic impacts of multiple water users distributed throughout a stream network. We analyse the effects of vineyard water management on environmental flows to (i) evaluate streamflow impacts from small storage ponds designed to meet human water demands and reduce summer diversions, (ii) prioritise the placement of storage ponds to meet human water needs while optimising environmental flow benefits and (iii) examine the environmental and social consequences of flow management policies designed to regulate the timing of diversions to protect ecosystem functions. 6. Thematic implications: spatially explicit models that represent anthropogenic stressors (e.g. water diversions) and environmental flow needs are required to address persistent and growing threats to freshwater biodiversity. A coupled human,natural system approach to water management is particularly useful in Mediterranean climates, characterised by severe competition for water resources and high spatial and temporal variability in flow regimes. However, lessons learned from our analyses are applicable to other highly seasonal systems and those that are expected to have increased precipitation variability resulting from climate change. [source] Architecture for dynamic and fair distribution of bandwidthINTERNATIONAL JOURNAL OF NETWORK MANAGEMENT, Issue 5 2006Vasil Hnatyshin The problem of fair distribution of available bandwidth among traffic flows or aggregates remains an essential issue in computer networks. This paper introduces a novel approach, called the Exact Bandwidth Distribution Scheme (X-BDS), for dynamic and fair distribution of available bandwidth among individual flows. In this approach, the edge routers keep per-flow information, while the core routers maintain the aggregate flow requirements. The X-BDS approach employs a distributed message exchange protocol for providing network feedback and for distributing aggregate flow requirements among the nodes in the network. Based on the obtained feedback, the edge routers employ the X-BDS resource management unit to dynamically distribute available bandwidth among individual flows. The X-BDS admission control and resource management units are responsible for fair resource allocation that supports minimum bandwidth guarantees of individual flows. This paper evaluates the Bandwidth Distribution Scheme through simulation and shows that the X-BDS is capable of supporting per-flow bandwidth guarantees in a dynamically changing network environment. Copyright © 2006 John Wiley & Sons, Ltd. [source] Different vasodilator responses of human arms and legsTHE JOURNAL OF PHYSIOLOGY, Issue 3 2004Sean C. Newcomer Forearm vascular responses to intra-arterial infusions of endothelium-dependent and -independent vasodilators have been thoroughly characterized in humans. While the forearm is a well-established experimental model for studying human vascular function, it is of limited consequence to systemic cardiovascular control owing to its small muscle mass and blood flow requirements. In the present study we determined whether these responses could be generalized to the leg. Based upon blood pressure differences between the leg and arm during upright posture, we hypothesized that the responsiveness to endothelium-dependent vasodilators would be greater in the forearm than the leg. Brachial and femoral artery blood flow (Q, ultrasound Doppler) at rest and during intra-arterial infusions of endothelium-dependent (acetylcholine and substance P) and -independent (sodium nitroprusside) vasodilators were measured in eight healthy men (22,27 years old). Resting blood flows in the forearm before infusion of acetylcholine, substance P or sodium nitroprusside were 25 ± 4, 30 ± 7 and 29 ± 5 ml min,1, respectively, and in the leg were 370 ± 32, 409 ± 62 and 330 ± 30 ml min,1, respectively. At the highest infusion rate of acetylcholine (16 ,g (100 ml tissue),1 min,1) there was a greater (P < 0.05) increase in Q to the forearm (1864 ± 476%) than to the leg (569 ± 86%). Similarly, at the highest infusion rate of substance P (125 pg (100 ml tissue),1 min,1) there was a greater (P < 0.05) increase in Q to the forearm (911 ± 286%) than to the leg (243 ± 58%). The responses to sodium nitroprusside (1 ,g (100 ml tissue),1 min,1) were also greater (P < 0.05) in the forearm (925 ± 164%) than in the leg (326 ± 65%). These data indicate that vascular responses to both endothelium-dependent and -independent vasodilator agents are blunted in the leg compared to the forearm. [source] Data analytics and stochastic modeling in a semiconductor fabAPPLIED STOCHASTIC MODELS IN BUSINESS AND INDUSTRY, Issue 1 2010Sugato Bagchi Abstract The scale, scope and complexity of the manufacturing operations in a semiconductor fab lead to some unique challenges in ensuring product quality and production efficiency. We describe the use of various analytical techniques, based on data mining, process trace data analysis, stochastic simulation and production optimization, to address these manufacturing issues, motivated by the following two objectives. The first objective is to identify the sub-optimal process conditions or tool settings that potentially affect the process performance and product quality. The second objective is to improve the overall production efficiency through better planning and resource scheduling, in an environment where the product mix and process flow requirements are complex and constantly changing. Copyright © 2010 John Wiley & Sons, Ltd. 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