Final Section (final + section)

Distribution by Scientific Domains
Distribution within Humanities and Social Sciences


Selected Abstracts


Free will in context: a contemporary philosophical perspective

BEHAVIORAL SCIENCES & THE LAW, Issue 2 2007
Patrick Grim B.Phil., Ph.D.
Philosophical work on free will is inevitably framed by the problem of free will and determinism. This paper offers an overview of the current state of the philosophical art. Early sections focus on quantum indeterminism, an outline of the most influential logical argument for incompatibilism between free will and determinism, and telling problems that face incompatibilism. A major portion of the paper focuses on the compatiblist alternative, favored by many working philosophers. The conditional account of free will offered by classical compatibilism can be shown to be inadequate. A number of compatibilist options remain open, however, and seem promising for future research. These include ,hierarchical' or ,mesh' accounts of free will, normative perspectives and an approach to free will in terms of an emphasis on context. Final sections draw out the implications of contemporary compatibilism for the brain and behavioral sciences and for the law. Copyright © 2007 John Wiley & Sons, Ltd. [source]


A strategy to communicate corporate social responsibility: cause related marketing and its dark side

CORPORATE SOCIAL RESPONSIBILITY AND ENVIRONMENTAL MANAGEMENT, Issue 1 2009
Ilaria Baghi
Abstract Cause related marketing (CRM) is a strategy that aims to communicate a company's striving for corporate social responsibility and to improve brand image. A strategy to increase consumers' emotional involvement toward a product,cause association is to describe the cause in vivid terms. In two experiments we investigated how vivid messages might increase the effectiveness of CRM strategy. We sought to demonstrate that a vivid description of the cause could influence consumers' preferences and trust in the effective use of money collected by selling the product. Experiment 1 results showed that individuals prefer products associated with a vivid message of the social cause rather than products associated with a pallid message. Experiment 2 results suggested that vivid messages induce more positive affective reactions and a higher trust in the effective use of money than pallid ones. In the final section, the implications of CRM for corporate social responsibility are discussed. Copyright © 2008 John Wiley & Sons, Ltd and ERP Environment. [source]


Why are Europeans so tough on migrants?

ECONOMIC POLICY, Issue 44 2005
Tito Boeri
SUMMARY European migration International migration can significantly increase income per capita in Europe. We estimate that at the given wage and productivity gap between Western and Eastern Europe, migration of 3% of the Eastern population to the West could increase total EU GDP by up to 0.5%. Yet on 1 May 2004, 14 EU countries out of 15 adopted transitional arrangements vis-à-vis the new member states and national migration restrictions vis-à-vis third country nationals are getting stricter and stricter. In this paper we offer two explanations for this paradox and document their empirical relevance in the case of the EU enlargement. The first explanation is that immigration to rigid labour markets involves a number of negative externalities on the native population. The second explanation is that there are important cross-country spillovers in the effects of migration policies, inducing a race-to-the top in border restrictions with high costs in terms of foregone European output. In light of our results, we discuss, in the final section, the key features of a desirable migration policy to be coordinated at the EU level. ,Tito Boeri and Herbert Brücker [source]


The Rift: Explaining Europe's Divergent Iraq Policies in the Run-Up of the American-Led War on Iraq

FOREIGN POLICY ANALYSIS, Issue 3 2006
JÜRGEN SCHUSTER
America's plan to attack Iraq split Europe down the middle. Why did European countries take such different stances toward the Bush administration's policy? This article examines three different approaches, each rooted in one of international relations (IRs) prominent schools of thought, with regard to their explanatory power in this specific puzzle. Firstly, it shows that public opinion (utilitarian,liberal approach) cannot account for whether a state joined the "coalition of the willing" or not. Secondly, it demonstrates that in Eastern Europe systemic forces of power relations (neorealist approach) are suitable for explaining state behavior, but not in Western Europe. Thirdly, it shows that the ideological orientations of governments (liberal,constructivist approach) were the decisive factor in determining whether a state supported the United States in Western Europe, but not in Eastern Europe. These results offer some interesting insights for the theoretical debate in IRs theory and foreign policy analysis, which are discussed in the final section of the article. In regard to foreign policy analysis, for example, the results of this study propose to "bring political parties in." [source]


The Christian Religion in Modern European and World History: A Review of The Cambridge History of Christianity, 1815,2000

HISTORY COMPASS (ELECTRONIC), Issue 6 2008
David Lindenfeld
Volumes 8 and 9 of the Cambridge History, representing the work of 72 scholars, reflect two major recent historiographical trends: 1) the increased attention paid to religion in modern European history, and 2) the increasing importance of Christianity in as a topic in world history. While these volumes serve to summarize the work already done in the first field, with articles on a wide variety of European countries, they should significantly move the second field forward by bringing together the work of specialists on many different parts of the world in a single place. Volume 8 summarizes scholarship on the Western religious revivals of the nineteenth century, both Catholic and Protestant. By integrating religion and politics, it also presents a more complex picture of the formation of European national identities than Benedict Anderson's Imagined Communities suggests. One third of the volume is devoted to the spread of Christianity to the non-Western world. In Volume 9, the European and world history perspectives are more evenly interspersed. Major themes include the papacy, ecumenism, colonialism, Pentecostalism, and the independent churches of Africa and Asia. The 1960s emerge as a turning point, if for different reasons in different parts of the world. This was the decisive period of secularization in Europe, and the final section documents the social and cultural impact of that shift, particularly on the arts. Although there are inevitable gaps in coverage, these volumes will serve as an invaluable research tool for years to come. [source]


Non-isothermal plasticity model for cyclic behaviour of soils

INTERNATIONAL JOURNAL FOR NUMERICAL AND ANALYTICAL METHODS IN GEOMECHANICS, Issue 5 2008
L. Laloui
Abstract On the one hand, it has been observed that liquefaction-induced shear deformation of soils accumulates in a cycle-by-cycle pattern. On the other hand, it is known that heating could induce plastic hardening. This study deals with the constitutive modelling of the effect that heat may have on the cyclic mechanical properties of cohesive soils, a relatively new area of interest in soil mechanics. In this paper, after a presentation of the thermo-mechanical framework, a non-isothermal plasticity cyclic model formulation is presented and discussed. The model calibration is described based on data from laboratory sample tests. It includes numerical simulations of triaxial shear tests at various constant temperatures. Then, the model predictions are compared with experimental results and discussed in the final section. Both drained and undrained loading conditions are considered. The proposed constitutive model shows good ability to capture the characteristic features of behaviour. Copyright © 2007 John Wiley & Sons, Ltd. [source]


Pedagogy Against the State

INTERNATIONAL JOURNAL OF ART & DESIGN EDUCATION, Issue 3 2008
Dennis Atkinson
The text of this article was originally presented in a public lecture in February 2008. It presents a description of earlier research on children's drawing practices which considers the ingenuity of learning and meaning-making through drawing. Then the focus moves to the language of assess-mentto consider how, art practices, such as drawing, as well as learner and teacher identities, are constructed and regulated within such linguistic practices (discourses). Bearing in mind the regulatory effect of such practices (and that all discourses are in some way regulatory) the final section introduces the idea of pedagogy against the state in order to think again an ethics of pedagogy concerned with becoming; an ethical imperative for pedagogy concerned with expanding our grasp of what learning is. [source]


The Antinomies of the Postpolitical City: In Search of a Democratic Politics of Environmental Production

INTERNATIONAL JOURNAL OF URBAN AND REGIONAL RESEARCH, Issue 3 2009
ERIK SWYNGEDOUW
Abstract In recent years, urban research has become increasingly concerned with the social, political and economic implications of the techno-political and socio-scientific consensus that the present unsustainable and unjust environmental conditions require a transformation of the way urban life is organized. In the article, I shall argue that the present consensual vision of the urban environment presenting a clear and present danger annuls the properly political moment and contributes to what a number of authors have defined as the emergence and consolidation of a postpolitical and postdemocratic condition. This will be the key theme developed in this contribution. First, I shall attempt to theorize and re-centre the political as a pivotal moment in urban political-ecological processes. Second, I shall argue that the particular staging of the environmental problem and its modes of management signals and helps to consolidate a postpolitical condition, one that evacuates the properly political from the plane of immanence that underpins any political intervention. The consolidation of an urban postpolitical condition runs, so I argue, parallel to the formation of a postdemocratic arrangement that has replaced debate, disagreement and dissensus with a series of technologies of governing that fuse around consensus, agreement, accountancy metrics and technocratic environmental management. In the third part, I maintain that this postpolitical consensual police order revolves decidedly around embracing a populist gesture. However, the disappearance of the political in a postpolitical arrangement leaves all manner of traces that allow for the resurfacing of the properly political. This will be the theme of the final section. I shall conclude that re-centring the political is a necessary condition for tackling questions of urban environmental justice and for creating egalibertarian socio-ecological urban assemblages. Résumé Récemment, la recherche urbaine a montré un intérêt croissant pour les implications sociales, politiques et économiques du consensus techno-politique et socio-scientifique selon lequel les conditions environnementales actuelles, non viables et injustes, exigent que soit transformé le mode d'organisation de la vie urbaine. Or, cette perspective consensuelle de l'environnement urbain soumis à un danger manifeste et réel annihile le moment véritablement politique et contribue à ce que de nombreux auteurs ont défini comme l'apparition et la consolidation d'une situation post-politique et post-démocratique. Traitant ce thème essentiel, l'article tente d'abord de conceptualiser et de recentrer le politique en tant que moment critique dans les processus politico-écologiques urbains. Ensuite, il montrera que la mise en scène particulière du problème environnemental et de ses modes de gestion indique, et aide à consolider, un état post-politique, dans lequel le véritablement politique est évacué du plan de l'immanence sous-jacent à toute intervention politique. La consolidation d'une situation post-politique urbaine se fait en parallèle à la formation d'un dispositif post-démocratique qui a remplacé débat, désaccord et dissension par une panoplie de technologies gouvernementales gravitant autour de mesures de consensus, d'accord et de responsabilité, associées à une gestion technocratique de l'environnement. Une troisième partie soutient que cet ordre policé consensuel post-politique se rapproche nettement du geste populiste. Toutefois, la disparition du politique d'un dispositif post-politique laisse toutes sortes de traces permettant la réémergence du véritablement politique. Cet aspect est au c,ur de la dernière partie. Pour conclure, le recentrage du politique est un préalable au traitement des questions de justice en matière d'environnement urbain et à la création d'assemblages urbains socio-écologiques d'égaliberté. [source]


Message in a Metro: Building Urban Rail Infrastructure and Image in Delhi, India

INTERNATIONAL JOURNAL OF URBAN AND REGIONAL RESEARCH, Issue 2 2006
MATTI SIEMIATYCKI
The world over, infrastructure mega projects have become more prevalent, even as evidence suggests that such projects often experience significant cost overruns while failing to fully deliver on their projected benefits. In this light, this article will argue that continued support for infrastructure mega projects stems from the way that such projects are presented to the public. Using the case of the development of a metro railway in Delhi, India, it shows that galvanizing public support and attracting patrons to a public transit system stems from creating an all-round positive image that combines tangible variables with an intangible set of symbolic meanings. Of course, image is only an impression, and does not necessarily reflect reality. In this light, the final section of this article examines the broad physical and societal implications of the metro development in Delhi, and uncovers the driving forces behind the project. The article concludes that, in spite of the cultivation of a positive image, the specific metro form that was developed in Delhi to satisfy each of the special interest groups involved in its production might be specifically one that fails to suit the transportation needs of the city. [source]


The figure of the righteous individual in Rwanda

INTERNATIONAL SOCIAL SCIENCE JOURNAL, Issue 189 2006
Valérie Rosoux
This article examines the scope and limits of the figure of the righteous individual in Rwanda. To what extent does reference to such a figure promote national reconstruction? My reflections on this question are divided into three parts. The first examines the role played by the international community (non-governmental organisations, journalists, overseas academics) in the emergence of this figure. The second section attempts to delineate the figure's social depth, in its contradictory representations. What is the relationship between the public representation and living memory of the phenomenon? How do survivors, in particular, perceive this "figure of reconciliation"? The third and final section identifies a number of political uses for this figure. How do Rwanda's official representatives refer to those who perhaps personified Rwanda at the moment of its conflagration? My analysis shows that, far from eliciting even the slightest consensus from the population, this type of commemoration reveals the enduring rifts. Twelve years after the genocide, references to the past, whatever their nature, continue to cause divisions. [source]


Why ,Health' is not a Central Category for Public Health Policy

JOURNAL OF APPLIED PHILOSOPHY, Issue 2 2009
STEPHEN JOHN
abstract We normally think that public health policy is an important political activity. In turn, we normally understand the value of public health policy in terms of the promotion of health or some health-related good (such as opportunity for health), on the basis of the assumption that health is an important constituent or determinant of wellbeing. In this paper, I argue that the assumption that the value of public health policy should be understood in terms of health leads us to overlook important benefits generated by such policy. To capture these benefits we need to understand the ends of public health policy in terms of the promotion of ,physical safety'. I then go on to argue that the idea that ,health' is an important category for evaluating or estimating individuals' wellbeing in the normative context of social policy is confused. I then clarify the relationship between my arguments and QALY-based accounts of health assessment. In the final section of the paper, I defend this surprising conclusion against various attacks. [source]


Toward a Geography of the Globalization of Architecture Office Networks

JOURNAL OF ARCHITECTURAL EDUCATION, Issue 3 2005
PAUL L. KNOX
This paper examines the globalization of architectural practice, focusing on the global strategies of architectural firms in relation to those of advanced business services and to the evolving network of world cities that provides the spatial framework for economic globalization. A basic geography of global architecture office networks is identified, and multivariate statistical analysis is used to identify four distinctive global arenas in which architectural firms are involved. In a final section, the implications of these findings for architectural education are discussed. [source]


High-resolution millimeter-wave radar systems for visualization of unstructured outdoor environments

JOURNAL OF FIELD ROBOTICS (FORMERLY JOURNAL OF ROBOTIC SYSTEMS), Issue 10 2006
Graham Brooker
This paper examines the use of millimeter-wave radar systems for visualization and navigation in unstructured outdoor environments. Three types of radar systems are described. The first is a long range, 94 GHz, frequency modulated interrupted continuous wave radar which is capable of producing two-dimensional (2D) reflectivity images to a range of more than 3 km. This is intended for use in long-range path planning. The second is a class of medium range 77 GHz frequency modulated continuous wave (FMCW) radar with two axis mirror scanners which is capable of producing high resolution threedimensional (3D) imagery out to 500 m at a reasonably slow frame rate. The final class also operates using the FMCW principle, but at 94 GHz, to produce high resolution 2D and 3D images out to about 50 m at a much higher update rate. These shorter range sensors may be used to determine the traversability of the local terrain. The outputs produced by the different classes of radar are examined and the paper considers their advantages when compared to other sensors such as vision and scanning laser. Using radar images, the final section compiles rules for interpreting radar reflectivity images from a path-planning perspective. © 2006 Wiley Periodicals, Inc. [source]


Growth dynamics of dairy processing firms in the European Union

AGRICULTURAL ECONOMICS, Issue 3-4 2010
Cornelis Gardebroek
EU dairy processing industry; Dynamic panel data; Firm growth Abstract The structure of the dairy processing industry in the European Union has changed enormously in recent decades. In many countries, the industry is characterized by a few large companies with a big market share accompanied by many small processors that often produce for niche markets. This article investigates which factors relate to growth of dairy processing firms. Using a unique 10-year panel data set and recently developed dynamic panel data estimators, the growth process of dairy processors is investigated for six rather diverse European countries. The data structure and the estimation method allow for dealing with endogeneity issues in an appropriate way. Firm size growth measured in total assets is found to be affected by firm size, firm age, and financial variables. Growth in number of employees is only affected by firm age and lagged labor productivity. Implications for these results are given in the final section of the article. [source]


Recent developments in the high-performance chelation ion chromatography of trace metals

JOURNAL OF SEPARATION SCIENCE, JSS, Issue 11 2007
Pavel N. Nesterenko
Abstract There have been a number of significant developments in the high-performance chelation ion chromatography (HPCIC) of trace metals in recent years. This review focuses on these developments, while giving important information on the fundamental parameters controlling the chelation sorption mechanism, including type of chelating group, stability constants, kinetics, and column temperature. The discussion pays particular attention to the types and properties of efficient chelating stationary phases which have been fabricated for certain groups of metals. The review also describes a number of major improvements in postcolumn reaction detection including the use of the latest reagents and noise reduction strategies to improve sensitivity and reduce LOD. In the final section, an indication of the applicability of HPCIC to a range of complex sample types is given with some key examples and chromatograms using the latest high-efficiency chelating phases. [source]


Sentimental Visions of Empire in Eighteenth-Century Studies

LITERATURE COMPASS (ELECTRONIC), Issue 1 2009
Lynn Festa
This survey of recent critical work on the role played by the sentimental in eighteenth-century representations of empire is organized around four central issues. The first addresses the double-edged use of sentimental writing as a form of ideological mystification , the palliating representation of scenes of colonial violence and imperial exploitation as moments of benevolence or sentimental exchange , and as a form of critique , as a means of representing the causes and consequences of remote actions as an incitement to proper action. The second takes up the way sentimentality is entwined with questions of commerce as a means of thinking about relations across the vast distances of empire, focusing in particular on the way sentimental tropes enabled thinking about the emergence of the global. The third turns to the utility of sentimental language for forging bonds of sympathetic identification with broader communities of nation and of empire, with particular attention to the way the extension of sympathy to another imperils the sanctity of the feeling self, while the final section addresses the way sentimental tropes police the circulation of sympathetic feeling as the means of monitoring the very boundaries of the human in the context of eighteenth-century empire. Throughout I stress the need for more comparative work on the role played by the sentimental not only within different domains of imperial activity but also across periods, disciplines, and national discourses. The essay includes an extensive bibliography of recent studies of eighteenth-century sentimentality in relation to empire. [source]


New Expression Profiles of Voltage-gated Ion Channels in Arteries Exposed to High Blood Pressure

MICROCIRCULATION, Issue 4 2002
Robert H. Cox
The diameters of small arteries and arterioles are tightly regulated by the dynamic interaction between Ca2+ and K+ channels in the vascular smooth muscle cells. Calcium influx through voltage-gated Ca2+ channels induces vasoconstriction, whereas the opening of K+ channels mediates hyperpolarization, inactivation of voltage-gated Ca2+ channels, and vasodilation. Three types of voltage-sensitive ion channels have been highly implicated in the regulation of resting vascular tone. These include the L-type Ca2+ (CaL) channels, voltage-gated K+ (KV) channels, and high-conductance voltage- and Ca2+ -sensitive K+ (BKCa) channels. Recently, abnormal expression profiles of these ion channels have been identified as part of the pathogenesis of arterial hypertension and other vasospastic diseases. An increasing number of studies suggest that high blood pressure may trigger cellular signaling cascades that dynamically alter the expression profile of arterial ion channels to further modify vascular tone. This article will briefly review the properties of CaL, KV, and BKCa channels, present evidence that their expression profile is altered during systemic hypertension, and suggest potential mechanisms by which the signal of elevated blood pressure may result in altered ion channel expression. A final section will discuss emerging concepts and opportunities for the development of new vasoactive drugs, which may rely on targeting disease-specific changes in ion channel expression as a mechanism to lower vascular tone during hypertensive diseases. [source]


Bringing the Moral Economy back in , to the Study of 21st-Century Transnational Peasant Movements

AMERICAN ANTHROPOLOGIST, Issue 3 2005
MARC EDELMAN
James Scott's The Moral Economy of the Peasant (1976) appeared at a time when "peasant studies" had begun to occupy an important place in the social sciences. The book's focus on Vietnam, as well as its novel argument about the causes of rural rebellion, attracted widespread attention and unleashed acerbic debates about peasants' "rationality" and the applicability of concepts from neoclassical economics to smallholding agriculturalists. In this article, I analyze E. P. Thompson's notion of "moral economy" and Scott's use of it to develop an experiential theory of exploitation. I then discuss other influences on Scott, including Karl Polanyi, A. V. Chayanov, and the Annales historians. "Moral economy" and "subsistence crisis" are concepts that Scott elaborated mainly in relation to village or national politics. In the final section of the article, I outline changes affecting peasantries in the globalization era and the continuing relevance of moral economic discourses in agriculturalists' transnational campaigns against the WTO. [source]


The Story of Abraham and Models of Human Identity

NEW BLACKFRIARS, Issue 1021 2008
Dr Mary Mills S.H.C.J
Abstract This paper explores the profiles of the women characters Sarah and Hagar as models of human identity. The two characters can only be explored through reading the over-arching narrative of the story of Abraham. Their profiles and narrated personalities have to be extracted from that narrative, but there is a two-sided nature of this necessity. If Sarah and Hagar cannot be separated from the biblical narrator's engagement with father Abraham, neither can Abraham function as father of the nations except through his interaction with these two women. The reader is thus led towards an understanding of how the stories of Genesis 12,24 deal with the issue of parenthood. The body of the paper consists in a close reading of the biblical material following a method of reading which is rooted in the use of imagination as an exegetical tool , a style adopted by Paul in his allegorical approach to Sarah and Hagar in Galatians 4. This approach opens into narrative criticism with a focus on characterisation and on the interactions of Sarah, Hagar and Abraham, caught up in a Domestic Comedy. The women's characters are explored through the themes of parenthood as other, the other woman and woman as other. A final section explores some of the points of narrative ethics to be extracted from the close textual readings of the paper, with reference to the writings of Paul Ricoeur and Emmanuel Levinas. It is suggested that female as well as male characters may offer fruitful models for human identity. [source]


Concurrent Enrollment in Arizona: Encouraging Success in High School

NEW DIRECTIONS FOR COMMUNITY COLLEGES, Issue 113 2001
Donald Puyear
This chapter presents a brief history of concurrent enrollment initiatives and then gives an overview of activity in Arizona, including research on student achievement, as well as tracking studies. In spite of growth in the number of programs and successes in student achievement, not everyone in the state understands and appreciates the benefits of the program; the final section of this chapter describes some of the realities of politics and necessary compromises. [source]


Traces of the secondary Geography curriculum

NEW ZEALAND GEOGRAPHER, Issue 2 2005
Lex Chalmers
Abstract:, Expressions of dissatisfaction about the post-compulsory Geography curriculum in the early 1970s were unusually concerted, leading to the creation of a National Geography Curriculum Committee. This essay reviews this history and the resulting Syllabus for Schools: Geography Forms 5,7 as a prelude to a discussion of contemporary curriculum development. The essay argues that curriculum development from 1975 and the ,education reforms' of the late 1980s failed to produce conditions in which satisfactory outcomes for a Geography curriculum can be assured in 2005, and that a new and concerted period of participation in curriculum discussion is required. Some goals for this process are outlined in the final section of the paper. [source]


Taking Animals Seriously: William Wordsworth and the Claims of Ecological Romanticism

ORBIS LITERARUM, Issue 4 2000
Peter Mortensen
Critics have long been aware that William Wordsworth borrowed from the German balladist Gottfried August Bürger in composing Lyrical Ballads (1798/1800). Wordsworth was both attracted and repulsed by Bürger's sensational and sensationally popular verse, yet the reason for this ambiguity has continued to baffle scholars. In this essay I turn to ecological criticism to cast a new light on the intertextual and cross-cultural exchange between Bürger's "Der Wilde Jäger" and Wordsworth's "Hart-Leap Well". Wordsworth, I claim, was intrigued by Bürger's attempt to write a poem about hunting, yet in rewriting the German ballad Wordsworth also seeks to shift the emphasis somewhat, in such a way as to focus more explicitly on what he believed to be the main issue at stake: man's shockingly cruel treatment of animals. In thus reconceptualising Bürger's poem, Wordsworth inaugurates a new kind of Romantic nature poetry, which brings animals into the foreground and takes their suffering seriously. In the essay's final section, I defend Wordsworth's proto-ecological vision against critics who believe that Wordsworth's love of nature caused him to lose interest in mankind. Far from leading necessarily to misanthropy or disillusionment, I argue, the vision propounded in ,Hart-Leap Well' invites us to speculate how we can combine concern for the environment with a concern for our fellow men. [source]


Cystic fibrosis lung disease starts in the small airways: Can we treat it more effectively?

PEDIATRIC PULMONOLOGY, Issue 2 2010
Harm A.W.M. Tiddens MD
Abstract The aims of this article are to summarize existing knowledge regarding the pathophysiology of small airways disease in cystic fibrosis (CF), to speculate about additional mechanisms that might play a role, and to consider the available or potential options to treat it. In the first section, we review the evidence provided by pathologic, physiologic, and imaging studies suggesting that obstruction of small airways begins early in life and is progressive. In the second section we discuss how the relationships between CF transmembrane conductance regulator (CFTR), ion transport, the volume of the periciliary liquid layer and airway mucus might lead to defective mucociliary clearance in small airways. In addition, we discuss how chronic endobronchial bacterial infection and a chronic neutrophilic inflammatory response increase the viscosity of CF secretions and exacerbate the clearance problem. Next, we discuss how the mechanical properties of small airways could be altered early in the disease process and how remodeling can contribute to small airways disease. In the final section, we discuss how established therapies impact small airways disease and new directions that may lead to improvement in the treatment of small airways disease. We conclude that there are many reasons to believe that small airways play an important role in the pathophysiology of (early) CF lung disease. Therapy should be aimed to target the small airways more efficiently, especially with drugs that can correct the basic defect at an early stage of disease. Pediatr Pulmonol. 2010; 45:107,117. © 2010 Wiley-Liss, Inc. [source]


Tom Morawetz's "Robust Enterprise": Jurisprudence after Wittgenstein

PHILOSOPHICAL INVESTIGATIONS, Issue 2 2006
Thomas D. Eisele
I examine one theme within Tom Morawetz's complex jurisprudential work (stemming from Wittgenstein): the concept of a practice. After considering this theme in some detail, I then sketch a different jurisprudential approach that still proceeds within the inspiration of Wittgenstein's later philosophy. Here, I summarise Stanley Cavell's elaborate recounting of Wittgenstein's twin concepts, "criteria" and "grammar." In a third and final section, I employ this alternative method to provide a brief example of how a Wittgensteinian approach might be made towards explicating and understanding Holmes' classic claim regarding the need in jurisprudence to separate legal and moral concepts. [source]


Time-resolved synchrotron diffraction and theoretical studies of very short-lived photo-induced molecular species

ACTA CRYSTALLOGRAPHICA SECTION A, Issue 2 2010
Philip Coppens
Definitive experimental results on the geometry of fleeting species are at the time of writing still limited to monochromatic data collection, but methods for modifications of the polychromatic Laue data to increase their accuracy and their suitability for pump,probe experiments have been implemented and are reviewed. In the monochromatic experiments summarized, excited-state conversion percentages are small when neat crystals are used, but are higher when photoactive species are embedded in an inert framework in supramolecular crystals. With polychromatic techniques and increasing source brightness, smaller samples down to tenths of a micrometre or less can be used, increasing homogeneity of exposure and the fractional population of the excited species. Experiments described include a series of transition metal complexes and a fully organic example involving excimer formation. In the final section, experimental findings are compared with those from theoretical calculations on the isolated species. Qualitative agreement is generally obtained, but the theoretical results are strongly dependent on the details of the calculation, indicating the need for further systematic analysis. [source]


The Politics of Perception: Use and Abuse of Transparency International's Approach to Measuring Corruption

POLITICAL STUDIES, Issue 4 2009
Staffan Andersson
The annual Corruption Perceptions Index (CPI), published by Transparency International (TI), has had a pivotal role in focusing attention on corruption. Despite recent critiques of the CPI, it remains highly influential on research into the causes of corruption and is also extensively used to galvanise support for measures to fight corruption. In this article we explore the CPI in more depth in order to highlight how the index has been used for political ends which may not always turn out to be supportive of anti-corruption efforts. The argument is developed in four sections: in the first, we focus on Transparency International's definition of corruption, highlighting some conceptual difficulties with the approach adopted and its relationship to the promotion of ,good governance' as the principal means of combating corruption. In the second section, we outline some methodological difficulties in the design of the Corruption Perceptions Index. Although the CPI has been much criticised, we demonstrate in the third section that the index continues to exercise great influence both in academic research and in the politics of anti-corruption efforts, particularly as exercised by Transparency International itself. In the final section we argue that the CPI contributes to the risk of creating a ,corruption trap' in countries where corruption is deeply embedded, as development aid is increasingly made conditional on the implementation of reforms which are impossible to achieve without that aid. [source]


Polymers with benzofuro-benzofuran structures,

POLYMER INTERNATIONAL, Issue 10 2002
Behzad Pourabas
Abstract Several kinds of molecules and also polymers are going to be discussed in the present article. Common feature in these molecules and polymers is the possessing of a specific structural part, namely benzofuro,benzofuran. This structure will appear in several molecules and kinds of polymers in the text. A condensation reaction between glyoxal and phenols is the reaction needed to produce the mentioned structural part, ie benzofuro,benzofuran. Because of the importance of this reaction, a brief historical background in the initial section of the article, and some discussion on the structural assignment of the reaction product and the reaction mechanism is also given in sections later on. Types of polymers, which are discussed in this article, are mainly heat stable polymers including polyamide, poly(ether ketone sulfone), polybenzimidazole, poly(amide-benzimidazole) and polyarylates. Polyester, polyhaydrezide and polymers with NLO property are the other kinds of the discussed polymers in the text with the benzofuro,benzofuran structure in their main chain. There is not any detailed procedure provided in the text about the synthesis of the molecules or even the polymers and the general procedures provided follow only the methodological purposes of the authors. Thermal properties of the polymers are discussed in the final section of the article with an attempt to provide a comparative argument in order to reach a relationship between structure and thermal properties. © 2001 Society of Chemical Industry. [source]


How to bring about change in the Bangladesh civil service?

PUBLIC ADMINISTRATION & DEVELOPMENT, Issue 3 2009
Attempts to change mindsets, behaviours, practice
Abstract This article addresses three critical questions central to many donor funded programmes which seek to enable pro-poor reform and growth. In the context of Bangladesh, the research asks first, does the civil service has a role in promoting change of this kind? Second, can a senior civil service development programme succeed in creating reform minded civil servants? And, third, if so how might the contribution be made both more substantive and of value? These questions are addressed systematically through a literature review and evidence drawn from Managing at the Top (MATT 2),a DFID funded programme. Some tentative conclusions are drawn in the final section. Copyright © 2009 John Wiley & Sons, Ltd. [source]


Classical and contemporary Italy in Roger Ascham's The Scholemaster (1570)

RENAISSANCE STUDIES, Issue 2 2002
Melanie Ord
This article seeks to show that a consideration of the use of Italy in Roger Ascham's The Scholemaster (1570) is illuminated by a study of the structural progression of book 1 (from educational methodologies, to a declamation against courtly vices, to an objection to travel to Italy). Specifically, it argues that the final section on Italy is conceived as a threat to those pedagogical and moral ideals of order, discipline and discrimination outlined in earlier sections; and that this closing statement forcibly demonstrates, and gives particular expression to, Ascham's humanist commitment to maintaining such well-schooled qualities against pernicious contemporary influences. Attention directed to the range of concerns addressed in the text also points to Ascham's conflicted use of Italy. For whilst his humanist educative project accompanies a concern to privilege the moral and cultural influences of classical over contemporary Italy, his national project of literary acculturation (witnessed in such things as his objection to courtly versifying) involves an attempt to conflate, rather than to distinguish, specific Italian identities. [source]


Heterogeneity in dynamic discrete choice models

THE ECONOMETRICS JOURNAL, Issue 1 2010
Martin Browning
Summary, We consider dynamic discrete choice models with heterogeneity in both the levels parameter and the state dependence parameter. We first present an empirical analysis that motivates the theoretical analysis which follows. The theoretical analysis considers a simple two-state, first-order Markov chain model without covariates in which both transition probabilities are heterogeneous. Using such a model we are able to derive exact small sample results for bias and mean squared error (MSE). We discuss the maximum likelihood approach and derive two novel estimators. The first is a bias corrected version of the Maximum Likelihood Estimator (MLE) although the second, which we term MIMSE, minimizes the integrated mean square error. The MIMSE estimator is always well defined, has a closed-form expression and inherits the desirable large sample properties of the MLE. Our main finding is that in almost all short panel contexts the MIMSE significantly outperforms the other two estimators in terms of MSE. A final section extends the MIMSE estimator to allow for exogenous covariates. [source]