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Fibreoptic Bronchoscopy (fibreoptic + bronchoscopy)
Selected AbstractsAwake nasal intubation using a combination of the EndoFlex® tube and fibreoptic bronchoscopy in patients with difficult airwaysACTA ANAESTHESIOLOGICA SCANDINAVICA, Issue 1 2010J. H. Liu No abstract is available for this article. [source] Difficult paediatric intubation when fibreoptic laryngoscopy failsPEDIATRIC ANESTHESIA, Issue 9 2002Agnes Ng Summary We report an unusual problem with fibreoptic bronchoscopy in an 8-year-old girl with Negar syndrome. She had a history of difficult airway since birth, and had undergone mandibular distraction for severe obstructive sleep apnoea when she was aged 2 years. Nagar syndrome is a Treacher,Collins like syndrome with normal intelligence, conductive bone deafness and problems with articulation. The patients have malar hypoplasia with down slanting palpebral fissures, high nasal bridge, micrognathia, absence of lower eyelashes, low set posteriorly rotated ears, preauricular tags, atresia of external ear canal, cleft palate, hypoplasia of thumb, with or without radius, and limited elbow extension. Protracted attempts with a fibreoptic bronchoscope failed to visualize the glottis, and this was only possible when the tube was guided to the larynx by blind nasal intubation. Apparently, the healing of the wounds for the mandibular distraction in the mandibular space on the inside of the rami of the mandible had caused differential fibrosis on either side of the hyoid, leading to a triplane distortion of the larynx with a left shift, clockwise rotation to a 2,8 o'clock direction and a slight tilt towards the left pharyngeal wall. The large epiglottis overlying this had precluded a view of the larynx. Finally, the older technique of breathguided intubation facilitated fibreoptic bronchoscopy to achieve tracheal intubation. [source] Multiple tracheobronchial mucosal lesions in two cases of Churg,Strauss syndromeRESPIROLOGY, Issue 1 2006Hidekazu MATSUSHIMA Abstract: Churg,Strauss syndrome (CSS) is characterized by hypereosinophilia and a systemic necrotizing vasculitis seen almost exclusively in patients with asthma. The most common pathological findings in the chest in CSS are eosinophilic pneumonia, necrotizing vasculitis and granulomatous inflammation (extravascular granuloma). However, tracheobronchial mucosal lesions have rarely been reported in CSS. The authors report two patients with CSS who had multiple tracheobronchial mucosal lesions that were found by fibreoptic bronchoscopy. They were tiny nodular lesions and necrotizing bronchial inflammation with many eosinophils was observed upon pathological examination. The authors concluded that tracheobronchial mucosal lesions may be one of the manifestations of vasculitis seen in CSS. [source] Is quantitative PCR for the pneumolysin (ply) gene useful for detection of pneumococcal lower respiratory tract infection?CLINICAL MICROBIOLOGY AND INFECTION, Issue 6 2009G. Abdeldaim Abstract The pneumolysin (ply) gene is widely used as a target in PCR assays for Streptococcus pneumoniae in respiratory secretions. However, false-positive results with conventional ply -based PCR have been reported. The aim here was to study the performance of a quantitative ply -based PCR for the identification of pneumococcal lower respiratory tract infection (LRTI). In a prospective study, fibreoptic bronchoscopy was performed in 156 hospitalized adult patients with LRTI and 31 controls who underwent bronchoscopy because of suspicion of malignancy. Among the LRTI patients and controls, the quantitative ply -based PCR applied to bronchoalveolar lavage (BAL) fluid was positive at ,103 genome copies/mL in 61% and 71% of the subjects, at ,105 genome copies/mL in 40% and 58% of the subjects, and at ,107 genome copies/mL in 15% and 3.2% of the subjects, respectively. Using BAL fluid culture, blood culture, and/or a urinary antigen test, S. pneumoniae was identified in 19 LRTI patients. As compared with these diagnostic methods used in combination, quantitative ply -based PCR showed sensitivities and specificities of 89% and 43% at a cut-off of 103 genome copies/mL, of 84% and 66% at a cut-off of 105 genome copies/mL, and of 53% and 90% at a cut-off of 107 genome copies/mL, respectively. In conclusion, a high cut-off with the quantitative ply -based PCR was required to reach acceptable specificity. However, as a high cut-off resulted in low sensitivity, quantitative ply -based PCR does not appear to be clinically useful. Quantitative PCR methods for S. pneumoniae using alternative gene targets should be evaluated. [source] |