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Selected AbstractsA case study of shell at Sakhalin: having a whale of a time?CORPORATE SOCIAL RESPONSIBILITY AND ENVIRONMENTAL MANAGEMENT, Issue 3 2008Subhasis Ray Abstract This is a case study on the world's largest oil and gas project, at the Sakhalin Islands, Russia. Shell is the key promoter of this project. The case highlights the sustainability challenges that Shell faced when working on the mega-project. By their very nature, all such projects involve disruptions in the environmental and social fabric of the project site. NGOs often take up these issues and create international headlines, bringing pressure on the management team. The Russian government also changed its stand over a period of time. While many of these issues are valid in their own way, they often create managerial dilemmas. Traditional management approaches to community development and environmental conservation fell short of stakeholder expectations at Sakhalin. The issue of saving around 100 endangered whales put a cloud of doubt over this $20 billion project. The case highlights strategic issues involved in crafting sustainability strategies at mega-projects, possible pitfalls and the challenge of balancing project execution and stakeholder commitments against an unstable political backdrop. As Shell plans to start many exploration projects in bio-diversity rich parts of the world, the Sakhalin project acts as a pilot to and reminder of social responsibility challenges to big multi-nationals. Copyright © 2007 John Wiley & Sons, Ltd and ERP Environment. [source] Assessing the habitat quality of oil mallees and other planted farmland vegetation with reference to natural woodlandECOLOGICAL MANAGEMENT & RESTORATION, Issue 3 2009F. Patrick Smith Summary, Much of the tree and shrub planting that has been conducted on farms in Western Australia over the past three decades has not been done with the specific intention of creating habitat or conserving biodiversity, particularly commercially oriented monocultures like oil mallee plantings. However, such plantings may nonetheless provide some habitat resources for native plants and animals. This study assessed the habitat quality of farm plantings (most of which were not planted with the primary intention of biodiversity conservation) at 72 sites across a study region in the central wheatbelt of Western Australia. Widely accepted habitat metrics were used to compare the habitat resources provided by planted farmland vegetation with those provided by remnant woodland on the same farms. The impact of adjacency of plantings to woodland and, in the case of oil mallees, the planting configuration on predicted habitat quality is assessed. Condition Benchmarks for five local native vegetation communities are proposed. Farmland plantings achieved an average Vegetation Condition Score (VCS) of 46 out of a possible 100, while remnant woodland on the same farms scored an average 72. The average scores for farm plantings ranged from 38,59 depending on which of five natural vegetation communities was used as its benchmark, but farm plantings always scored significantly less than remnant woodland (P < 0.001). Mixed species plantings on average were rated more highly than oil mallees (e.g. scores of 42 and 36 respectively using the Wandoo benchmark) and adjacency to remnant woodland improved the score for mixed plantings, but not for oil mallees. Configuration of oil mallees as blocks or belts (i.e. as an alley farming system) had no impact on the VCS. Planted farmland vegetation fell short of remnant woodland in both floristic richness (51 planted native species in total compared with a total of more than 166 naturally occurring plant species in woodland) and structural diversity (with height, multiple vegetation strata, tree hollows and woody debris all absent in the relatively young 7,15-year-old farm plantings). Nonetheless farmland plantings do have measurable habitat values and recruitment and apparent recolonization of plantings with native plant species was observed. Habitat values might be expected to increase as the plantings age. The VCS approach, including the application of locally relevant Benchmarks is considered to be valuable for assessing potential habitat quality in farmland vegetation, particularly as a tool for engaging landholders and natural resource management practitioners. [source] Psychotherapy as a Rite of PassageFAMILY PROCESS, Issue 4 2007C. CHRISTIAN BEELS M.D. Some psychotherapies may work because they resemble rites of passage. To explore this idea, this article describes an "individual" case of depression in which drug, cognitive, and narrative approaches fell short of effectiveness, and change occurred in a series of experiences that resemble a rite of passage. This resemblance is illuminated by examining two apparently quite different healing processes,Alcoholics Anonymous and multifamily group therapy in schizophrenia,to explore the elements they have in common with the case described: the acceptance of what Victor Turner called a liminal experience, and the importance of witnesses to the ritual support for that acceptance. The discussion contributes to a loosening of the distinctions between the processes of individual, family, group, and other social therapies and leads to questions about the expert knowledge the therapist provides. [source] Mortality after care among young adult foster children in SwedenINTERNATIONAL JOURNAL OF SOCIAL WELFARE, Issue 3 2001Bo Vinnerljung This exploratory study looks at mortality after care among 13,100 former Swedish foster children, placed before their teens. Sources used are two national databases, on child welfare interventions and causes of death. Risk ratios of death for foster children are compared with those of their peers in the general population and with a comparison group, consisting of 10,668 young adults from adverse home backgrounds, who never entered foster family care before their teens. Both ex-foster children and the comparison group were young adults (19,26 years old) at time of follow-up. Results show a moderately elevated risk ratio for both groups compared with peers in the general population, mainly due to more frequent unnatural deaths, especially suicides. Time at first placement was not related to mortality among men, but there was a weak tendency of a higher risk ratio for girls placed at age 7,12. Information on time spent in care is used with caution, due to possible problems with reliability. Almost all comparisons between the foster care and the comparison group fell short of statistical significance. For foster children who had spent more than five years in care, the risk ratio tended to be higher than for foster children with shorter care experience, and similar to that of the comparison group. Foster children who had been in care for less then six years thus tended to have a lower risk ratio than the comparison group. [source] Performance evaluation of the New Connecticut Leading Employment Index using lead profiles and BVAR modelsJOURNAL OF FORECASTING, Issue 6 2006Anirvan Banerji Abstract The leading and coincident employment indexes for the state of Connecticut developed following the recession of the early 1990s fell short of expectations. This paper performs two tasks. First, it describes the process of revising the Connecticut Coincident and Leading Employment Indexes. Second, it analyzes the statistical properties and performance of the new indexes by comparing the lead profiles of the new and old indexes as well as their out-of-sample forecasting performance, using the Bayesian Vector Autoregressive (BVAR) method. The new coincident index shows improved performance in dating employment cycle chronologies. The lead profile test demonstrates that superiority in a rigorous, non-parametric statistic fashion. The mixed evidence on the BVAR forecasting experiments illustrates that leading indexes properly predict cycle turning points and do not necessarily provide accurate forecasts except at turning points, a view that our results support.,,Copyright © 2006 John Wiley & Sons, Ltd. [source] The World Development Report: concepts, content and a Chapter 12,JOURNAL OF INTERNATIONAL DEVELOPMENT, Issue 3 2001Robert Chambers The World Development Report (WDR) process set new standards for openness and consultation. Its concepts and content are a major advance on its 1990 predecessor. The intention that its concepts and content should be influenced by voices of the poor was partly fulfilled. Conceptually, the VOP findings support the multidimensional view of poverty as ,pronounced deprivation of wellbeing', and the use of income-poverty to describe what is only one dimension of poverty (though this welcome usage is not consistent throughout in the WDR). Two concepts or analytical orientations were not adopted: powerlessness and disadvantage seen as a multidimensional interlinked web; and livelihoods. On content, three areas where the influence fell short were: how the police persecute and impoverish poor people; the diversity of the poorest people; and the significance of the body as the main but vulnerable and indivisible asset of many poor people. A weakness of the WDR is its lack of critical self-awareness. Chapter 11 is self-serving for the International Financial Institutions: it lumps loans with grants as concessional finance; it makes liberal use of the term donor, but never lender; and it does not consider debt avoidance as a strategy. The Report ends abruptly, a body without a head. Its multidimensional view of poverty is not matched by a multidimensional view of power and responsibility. A Chapter 12 is crying out to be written. This would confront issues of professional, institutional and personal commitment and change. It would stress critical reflection as a professional norm, disempowerment for democratic diversity as institutional practice, and personal values, attitudes and courageous behaviour as primary and crucial if development is to be change that is good for poor people. A new conclusion is suggested for the WDR, and a title for the World Development Report 2010. Copyright © 2001 John Wiley & Sons, Ltd. [source] The efficacy of orally dosed ketamine and ketamine/medetomidine compared with intramuscular ketamine in rhesus macaques (Macaca mulatta) and the effects of dosing route on haematological stress markersJOURNAL OF MEDICAL PRIMATOLOGY, Issue 3 2008Andrew N Winterborn Abstract Background, This study compared the efficacy of two orally-dosed (PO) anaesthetic regimens for chemical immobilization in rhesus macaques (Macaca mulatta), versus the standard protocol of intramuscular (TM) ketamine. In addition, the effects of dosing route on haematological stress markers were evaluated. Methods, Testing was conducted on 18 chronically housed animals. Animals were trained to accept oral dosing and then randomly assigned to one of three drug regimens: (1) ketamine IM, (2) ketamine PO, (3) Ketamine/medetomidine PO. Sedation levels for each regimen were evaluated. Results, Oral dosing alone was not sufficient to achieve a plane of sedation that allowed for safe handling. Serum cortisol and glucose levels were unchanged across groups, although differences were observed in the leukogram profiles. Conclusion, The oral dosages used in this study fell short in providing adequate sedation for safe handling for routine veterinary procedures. Leukogram profiles indicated that orally dosed animals experienced a higher level of stress. [source] Impact of Age at First Drink on Stress-Reactive DrinkingALCOHOLISM, Issue 1 2007Deborah A. Dawson Background: Although recent data from animal models indicate that adolescent ethanol exposure increases self-administered ethanol intake in adult rats, the impact of age at first drink on the association between stress and drinking has not been studied in humans. Methods: Data collected in the 2001 to 2002 National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) were used to estimate the extent to which age at first drink modified the association between stress and average daily volume (ADV) of ethanol intake in a sample of 26,946 past-year drinkers. Successive models estimated the magnitude and significance of the interaction between age at first drink (ages 14 or younger, 15,17, and 18 or older) and number of stressors (out of 12 past-year negative life events) after (1) adjusting for sociodemographic characteristics, (2) additionally adjusting for family history of alcoholism, comorbid psychopathology, adolescent, and past-year tobacco and illicit drug use, and (3) additionally adjusting for all other significant interactions with number of stressors. Results: Even after adjusting for a wide range of confounders and their interactions with stress, initiation of drinking at ages 14 and younger increased the association between the number of stressors and ADV of ethanol consumption by 8% (p=0.014), when considering the full range of 12 potential stressors. In fact, the positive association between stress and consumption was significant only for this group of drinkers with early adolescent exposure to ethanol. Within this group, ADV of consumption increased by an average of 7% with each additional stressor experienced, although the exact percentage increase varied as a function of other covariates that had significant interactions with stress. When a reduced set of 4 stressors was considered, the magnitudes of the associations were mostly unchanged, but the modifying effect of age at first drink fell short of statistical significance (p=0.309) in the fully adjusted model. Conclusions: The findings of this study are consistent with the argument that early-onset drinking may increase stress-reactive ethanol consumption; however, these findings need to be replicated in an experimental human study in order to control fully the direction of the relationship between stress and consumption. [source] Environmental temperature stress on drugs in prehospital emergency medical serviceACTA ANAESTHESIOLOGICA SCANDINAVICA, Issue 4 2003M. Helm Background: Drugs used in prehospital emergency medical service (EMS) in principle are subject to the same storage restrictions as hospital-based medications. The prehospital emergency environment however, often exceeds these storage recommendations. Main stress factors are sunlight, vibration and extreme temperature, which may lead to alteration in chemical and physical stability of stored pharmaceuticals, as well as microbiological contamination and concentration enhancement of pharmacological inserts. Methods: The purpose of this study was to determine the environmental temperature stress upon drugs used in the prehospital EMS under real mission conditions within different types of rescue vehicles (rescue helicopter [HEMS], ambulance [AMB] and emergency physician transport vehicle [EPTV]) during a ,summer' and ,winter' monitoring period (2 months duration each/location: southern Germany). Results: Recorded temperatures varied from ,13.2°C to +50.6°C. The recommended maximum storage temperature (+25°C) was exceeded in all rescue vehicles (33,45% of total exposure time), whereas the recommended minimum storage temperature (0°C) only fell short in the EPTV (19% of total exposure time). The daily maximum temperature variations ranged from 19.0°C (winter) to 32.9°C (summer). Conclusions: These results show that even in a moderate climatic zone, drugs used in prehospital EMS are significantly influenced by temperature stress; furthermore, these results recommend the usage of temperature-controlled drug boxes. [source] Dysautonomia rating scales in Parkinson's disease: Sialorrhea, dysphagia, and constipation,Critique and recommendations by movement disorders task force on rating scales for Parkinson's disease,MOVEMENT DISORDERS, Issue 5 2009Marian L. Evatt MD Abstract Upper and lower gastrointestinal dysautonomia symptoms (GIDS),sialorrhea, dysphagia, and constipation are common in Parkinson's disease (PD) and often socially as well as physically disabling for patients. Available invasive quantitative measures for assessing these symptoms and their response to therapy are time-consuming, require specialized equipment, can cause patient discomfort and present patients with risk. The Movement Disorders Society commissioned a task force to assess available clinical rating scales, critique their clinimetric properties, and make recommendations regarding their clinical utility. Six clinical researchers and a biostatistician systematically searched the literature for scales of sialorrhea, dysphagia, and constipation, evaluated the scales' previous use, performance parameters, and quality of validation data (if available). A scale was designated "Recommended" if the scale was used in clinical studies beyond the group that developed it, has been specifically used in PD reports, and clinimetric studies have established that it is a valid, reliable, and sensitive. "Suggested" scales met at least part of the above criteria, but fell short of meeting all. Based on the systematic review, scales for individual symptoms of sialorrhea, dysphagia, and constipation were identified along with three global scales that include these symptoms in the context of assessing dysautonomia or nonmotor symptoms. Three sialorrhea scales met criteria for Suggested: Drooling Severity and Frequency Scale (DSFS), Drooling Rating Scale, and Sialorrhea Clinical Scale for PD (SCS-PD). Two dysphagia scales, the Swallowing Disturbance Questionnaire (SDQ) and Dysphagia-Specific Quality of Life (SWAL-QOL), met criteria for Suggested. Although Rome III constipation module is widely accepted in the gastroenterology community, and the earlier version from the Rome II criteria has been used in a single study of PD patients, neither met criteria for Suggested or Recommended. Among the global scales, the Scales for Outcomes in PD-Autonomic (SCOPA-AUT) and Nonmotor Symptoms Questionnaire for PD (NMSQuest) both met criteria for Recommended, and the Nonmotor Symptoms Scale (NMSS) met criteria for Suggested; however, none specifically focuses on the target gastrointestinal symptoms (sialorrhea, dysphagia, and constipation) of this report. A very small number of rating scales have been applied to studies of gastrointestinal-related dysautonomia in PD. Only two scales met "Recommended" criteria and neither focuses specifically on the symptoms of sialorrhea, dysphagia, and constipation. Further scale testing in PD among the scales that focus on these symptoms is warranted, and no new scales are needed until the available scales are fully tested clinimetrically. © 2009 Movement Disorder Society [source] Deficiencies in nutritional intake in patients admitted with diabetes-related foot complicationsNUTRITION & DIETETICS, Issue 3 2007Sarah PITT Abstract Aim:, Adequate nutritional intake is an essential component for timely wound healing. The present research aimed to identify the frequency of inadequate dietary intake, including the specific nutritional elements most frequently lacking, in a group of patients admitted with diabetes-related foot complications. Methods:, Consecutive patients admitted to a diabetic foot unit underwent a dietary assessment, which included the retrospective collection of a seven-day food history for the period just prior to admission. The collected data were entered into FoodWorks, and comparisons were made with recommendations made by national guidelines. Results:, Thirty-five patients underwent nutritional assessment, 74% male and 26% having impaired renal function. Protein consumption was in excess of daily recommended intake, and although the overall fat intake as a percentage of total calories consumed was in keeping with national guidelines, the intake of saturated fat was inappropriately high. Of the 12 micronutrients assessed, niacin and vitamin C were appropriately consumed by all; average intake of potassium, phosphorus and thiamine approached recommended levels, while the intake of magnesium, calcium, zinc, riboflavin, folate and vitamin A all fell short of recommended daily requirements. No dietary differences were identified between individuals with normal and abnormal renal function, but deficiencies in calcium and iron were identified only in women. Conclusion:, Dietary deficiencies of macronutrients were not identified in individuals admitted with diabetes-related foot complications, but many patients were found to be consuming well below the daily recommended daily intake of one or more of the micronutrients deemed necessary for normal wound healing. [source] Physical growth in schoolchildren from Argentina: Comparison with Argentinean and CDC/NCHs growth referencesAMERICAN JOURNAL OF HUMAN BIOLOGY, Issue 3 2009Alicia B. Orden The aim of this study was to assess the physical growth of schoolchildren from Argentina by comparison with the CDC/NCHS and Argentinean growth references (AGR), to contribute to the discussion about the use of local or international references for the assessment of growth in developing countries. Weight and height were measured in 3,411 schoolchildren aged 5,14 years. Data were log-transformed and compared with both references by paired samples t -test (CI = 0.95; , = 0.005). The boys' weights were greater than CDC/NCHS (up to 10, and at 14 years old) and the national reference at all ages (P < 0.005). The girls also were heavier than CDC/NCHS (at 7 and 12 years old, P < 0.005) and AGR, except at age 11 and 14 years. In boys, height was lower than CDC/NCHS at 9 and 14 years of age, and higher than AGR at all ages (P < 0.005). The girls were also shorter than CDC/NCHS at 7, 13, and 14 years old (P < 0.005), and,except at age 14,taller than AGR. The weight was higher than both of the references. Height showed a clear dissociation from the national reference and minor differences from CDC/NCHS. Nevertheless, around puberty, the children's height fell short of CDC/NCHS, especially the girls, whose values approached those of their Argentinean peers. This divergence could be associated with cohort effects or population variations in adolescent growth spurt. The use of a single growth reference for preadolescent may be appropriate. The height decrease in adolescents suggests the usefulness of local standards at this period. Am. J. Hum. Biol. 2009. © 2008 Wiley-Liss, Inc. [source] SEXUAL MEDICINE HISTORY: Satyriasis: The Antiquity Term for Vulvodynia?THE JOURNAL OF SEXUAL MEDICINE, Issue 1 2006Janice McElhiney EdM ABSTRACT From ancient times, through the Middle Ages, and well into the 19th century, physicians concentrated on catastrophic medical conditions and illnesses rather than on quality of life issues. Wars, plagues, and pestilence left little time, energy, or concern for "discomfort" problems. Therefore, it is not surprising that women's conditions that caused distressing symptoms but fell short of major morbidity and mortality were not given a prominent position in medicine until relatively recently. This is especially the case with vulvodynia, a condition that has been reported to affect approximately 15% (and in some studies up to 27%) of the female population at some point in their lives. Despite its high prevalence, this condition was not discussed or reported in traditional medical textbooks until the end of the 1800s. Now, we propose another viewpoint on when the first description of vulvodynia appeared; that is, that vulvodynia was described as far back as the 1st century CE. From our review of the ancient medical literature, we believe that the condition described by Soranus as "satyriasis in females" was actually vulvodynia. McElhiney J, Kelly S, Rosen R, and Bachmann G. Satyriasis: the antiquity term for vulvodynia? J Sex Med 2006;3:161,163. [source] Tasmania's Tamar Valley Pulp Mill: A Comparison of Planning Processes Using a Good Environmental Governance FrameworkAUSTRALIAN JOURNAL OF PUBLIC ADMINISTRATION, Issue 3 2008Fred Gale In November 2004, the Tasmanian government requested the state's planning body, the Resource Planning and Development Commission (RPDC), to undertake an evaluation of a proposal to establish a pulp mill at Long Reach near Bell Bay on Tasmania's Tamar Estuary. In early 2007, Gunns Limited, the project's proponent, pulled out of the RPDC process and the government established an alternative, ,fast-track' process under the Pulp Mill Assessment Act (PMAA). This article evaluates the RPDC and the PMAA assessment processes using a ,good environmental governance' framework composed of eight criteria , transparency, accountability, openness, balance, deliberation, efficiency, science and risk. The comparison reveals that although the RPDC process fell short of the ideal, it was markedly superior to the PMAA process that replaced it. The case highlights how political economic power can be used to the detriment of public planning and the communities and environment that rely on it. [source] Optimal nitrogen supply as a key to increased and sustained production of a monoclonal full-size antibody in BY-2 suspension culture,BIOTECHNOLOGY & BIOENGINEERING, Issue 2 2010T. Holland Abstract Plant cell cultures have been used as expression hosts for recombinant proteins for over two decades. The quality of plant cell culture-produced proteins such as full-size monoclonal antibodies has been shown to be excellent in terms of protein folding and binding activity, but the productivity and yield fell short of what was achieved using mammalian cell culture, in which the key to gram-per-liter expression levels was strain selection and medium/process optimization. We carried out an extensive media analysis and optimization for the production of the full-size human anti-HIV antibody 2G12 in N. tabacum cv. BY-2. Nitrogen source and availability was found to be one key factor for the volumetric productivity of plant cell cultures. Increased amounts of nitrate in the culture medium had a dramatic impact on protein yields, resulting in a 10,20-fold increase in product accumulation through a combination of enhanced secretion and higher stability. The results were scalable from shake flasks to stirred-tank bioreactors, where the maximum yield per cultivation volume was 8,mg,L,1 over 7 days. During the stationary phase, antibody levels were 150-fold higher in nitrogen-enriched medium compared to standard medium. The enhanced medium appeared not to affect antibody quality and activity, as determined by Western blots, surface plasmon resonance binding assays and N -glycan analysis. Biotechnol. Bioeng. 2010;107: 278,289. © 2010 Wiley Periodicals, Inc. 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